HRP20010570A2 - Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth - Google Patents

Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth Download PDF

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Publication number
HRP20010570A2
HRP20010570A2 HR20010570A HRP20010570A HRP20010570A2 HR P20010570 A2 HRP20010570 A2 HR P20010570A2 HR 20010570 A HR20010570 A HR 20010570A HR P20010570 A HRP20010570 A HR P20010570A HR P20010570 A2 HRP20010570 A2 HR P20010570A2
Authority
HR
Croatia
Prior art keywords
pseudomonic acid
extract
solution
acid
isobutyl acetate
Prior art date
Application number
HR20010570A
Other languages
English (en)
Croatian (hr)
Inventor
Istvan Barta
Gyula Jerkovich
Ildiko Lang
Margit Bidlo
Vilmos Keri
David Leonov
Edit Nagy
Csaba Szabo
Aniko Tegdes
Janos Salat
Valeria Szell
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of HRP20010570A2 publication Critical patent/HRP20010570A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HR20010570A 1999-02-03 2000-02-03 Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth HRP20010570A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11844799P 1999-02-03 1999-02-03
PCT/US2000/002824 WO2000046388A1 (en) 1999-02-03 2000-02-03 Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth

Publications (1)

Publication Number Publication Date
HRP20010570A2 true HRP20010570A2 (en) 2002-08-31

Family

ID=22378653

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010570A HRP20010570A2 (en) 1999-02-03 2000-02-03 Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth

Country Status (23)

Country Link
US (1) US6245921B1 (https=)
EP (1) EP1147210A4 (https=)
JP (1) JP2002535996A (https=)
KR (1) KR20010112258A (https=)
CN (1) CN1345377A (https=)
AU (1) AU771214B2 (https=)
BG (1) BG105775A (https=)
BR (1) BR0009178A (https=)
CA (1) CA2360840A1 (https=)
CZ (1) CZ20012725A3 (https=)
HK (1) HK1041294A1 (https=)
HR (1) HRP20010570A2 (https=)
HU (1) HUP0105286A3 (https=)
IL (1) IL144678A0 (https=)
IS (1) IS6034A (https=)
MX (1) MXPA01007805A (https=)
NO (1) NO20013790L (https=)
PL (1) PL349153A1 (https=)
SK (1) SK10902001A3 (https=)
TR (1) TR200102232T2 (https=)
WO (1) WO2000046388A1 (https=)
YU (1) YU55501A (https=)
ZA (1) ZA200106057B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2360865A1 (en) 1999-02-03 2000-08-10 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid a antibiotic by microbiological method
CZ200467A3 (cs) * 2001-06-21 2004-10-13 Biogalágyogyszergyarárt Metabolicky řízený způsob fermentace pro výrobu pseudomonové kyseliny
PL371263A1 (en) 2001-12-28 2005-06-13 Biogal Gyogyszergyar Rt Processes for preparing crystalline and amorphous mupirocin calcium
IL150907A (en) * 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
CA2560984A1 (en) * 2004-06-01 2005-12-15 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for preparation of amorphous form of a drug
CN101124221B (zh) * 2005-02-21 2012-05-23 克利亚制药股份公司 莫匹罗星的提纯方法
GB2441328A (en) * 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
CN104370896A (zh) * 2013-11-29 2015-02-25 江苏汉邦科技有限公司 一种纯化假单孢菌素的方法
CN103820369B (zh) * 2014-03-07 2015-11-18 浙江瑞邦药业有限公司 一种萤光假单胞菌及其应用
CN109053707B (zh) * 2018-09-19 2021-08-17 福建康鸿生物科技有限公司 一种莫匹罗星的提纯方法
CN110823649A (zh) * 2019-10-21 2020-02-21 河南中烟工业有限责任公司 一种卷烟主流烟气中有机酸的收集方法和检测方法
EP4190780A4 (en) * 2020-08-25 2024-03-20 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. MUPIROCIN EXTRACTION PROCESS
US20240043888A1 (en) * 2021-02-07 2024-02-08 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Fermentation method for mupirocin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1395907A (en) 1971-06-12 1975-05-29 Beecham Group Ltd Antibiotics
JPS5270083A (en) 1975-12-04 1977-06-10 Yoshitomi Pharmaceut Ind Ltd Manufacture of an antibiotics, trans-pseudomonic acid
CA1103264A (en) * 1977-09-30 1981-06-16 Norman H. Rogers Purification of pseudomonic acid
CA1115699A (en) 1978-05-20 1982-01-05 Alan D. Curzons Lithium pseudomonate and its preparation
ZA923242B (en) * 1991-05-07 1993-01-27 Sankyo Co Novel anti-bacterial compound

Also Published As

Publication number Publication date
AU771214B2 (en) 2004-03-18
HUP0105286A3 (en) 2003-03-28
NO20013790L (no) 2001-10-02
BG105775A (bg) 2002-03-29
BR0009178A (pt) 2001-11-20
IL144678A0 (en) 2002-06-30
CZ20012725A3 (cs) 2002-03-13
IS6034A (is) 2001-08-01
HK1041294A1 (zh) 2002-07-05
YU55501A (sh) 2003-07-07
AU2980200A (en) 2000-08-25
KR20010112258A (ko) 2001-12-20
SK10902001A3 (sk) 2002-04-04
HUP0105286A2 (hu) 2002-05-29
EP1147210A4 (en) 2004-06-02
MXPA01007805A (es) 2003-06-04
CN1345377A (zh) 2002-04-17
US6245921B1 (en) 2001-06-12
WO2000046388A1 (en) 2000-08-10
EP1147210A1 (en) 2001-10-24
TR200102232T2 (tr) 2002-02-21
CA2360840A1 (en) 2000-08-10
JP2002535996A (ja) 2002-10-29
ZA200106057B (en) 2002-07-24
PL349153A1 (en) 2002-07-01
NO20013790D0 (no) 2001-08-02

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20050125

Year of fee payment: 6

PNAN Change of the applicant name, address/residence

Owner name: TEVA GYOGYSZERGYAR RESZVENYTARSASAG, HU

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