HK1041294A1 - 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 - Google Patents

从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 Download PDF

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Publication number
HK1041294A1
HK1041294A1 HK02103004.6A HK02103004A HK1041294A1 HK 1041294 A1 HK1041294 A1 HK 1041294A1 HK 02103004 A HK02103004 A HK 02103004A HK 1041294 A1 HK1041294 A1 HK 1041294A1
Authority
HK
Hong Kong
Prior art keywords
pseudomonic acid
aqueous
extract
isobutyl acetate
culture broth
Prior art date
Application number
HK02103004.6A
Other languages
English (en)
Chinese (zh)
Inventor
Barta Istvan
Tegdes Aniko
Szell Valeria
Szabo Csaba
Nagy Nee Arvai Edit
Keri Vilmos
Leonov David
Lang Ildiko
Bidlo Nee Igloy Margit
Jerkovich Gyula
Salat Janos
Original Assignee
Biogal Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt. filed Critical Biogal Gyogyszergyar Rt.
Publication of HK1041294A1 publication Critical patent/HK1041294A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK02103004.6A 1999-02-03 2000-02-03 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 HK1041294A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11844799P 1999-02-03 1999-02-03
US60/118,447 1999-02-03
PCT/US2000/002824 WO2000046388A1 (en) 1999-02-03 2000-02-03 Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth

Publications (1)

Publication Number Publication Date
HK1041294A1 true HK1041294A1 (zh) 2002-07-05

Family

ID=22378653

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103004.6A HK1041294A1 (zh) 1999-02-03 2000-02-03 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法

Country Status (23)

Country Link
US (1) US6245921B1 (https=)
EP (1) EP1147210A4 (https=)
JP (1) JP2002535996A (https=)
KR (1) KR20010112258A (https=)
CN (1) CN1345377A (https=)
AU (1) AU771214B2 (https=)
BG (1) BG105775A (https=)
BR (1) BR0009178A (https=)
CA (1) CA2360840A1 (https=)
CZ (1) CZ20012725A3 (https=)
HK (1) HK1041294A1 (https=)
HR (1) HRP20010570A2 (https=)
HU (1) HUP0105286A3 (https=)
IL (1) IL144678A0 (https=)
IS (1) IS6034A (https=)
MX (1) MXPA01007805A (https=)
NO (1) NO20013790L (https=)
PL (1) PL349153A1 (https=)
SK (1) SK10902001A3 (https=)
TR (1) TR200102232T2 (https=)
WO (1) WO2000046388A1 (https=)
YU (1) YU55501A (https=)
ZA (1) ZA200106057B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2360865A1 (en) 1999-02-03 2000-08-10 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid a antibiotic by microbiological method
CZ200467A3 (cs) * 2001-06-21 2004-10-13 Biogalágyogyszergyarárt Metabolicky řízený způsob fermentace pro výrobu pseudomonové kyseliny
PL371263A1 (en) 2001-12-28 2005-06-13 Biogal Gyogyszergyar Rt Processes for preparing crystalline and amorphous mupirocin calcium
IL150907A (en) * 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
CA2560984A1 (en) * 2004-06-01 2005-12-15 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for preparation of amorphous form of a drug
CN101124221B (zh) * 2005-02-21 2012-05-23 克利亚制药股份公司 莫匹罗星的提纯方法
GB2441328A (en) * 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
CN104370896A (zh) * 2013-11-29 2015-02-25 江苏汉邦科技有限公司 一种纯化假单孢菌素的方法
CN103820369B (zh) * 2014-03-07 2015-11-18 浙江瑞邦药业有限公司 一种萤光假单胞菌及其应用
CN109053707B (zh) * 2018-09-19 2021-08-17 福建康鸿生物科技有限公司 一种莫匹罗星的提纯方法
CN110823649A (zh) * 2019-10-21 2020-02-21 河南中烟工业有限责任公司 一种卷烟主流烟气中有机酸的收集方法和检测方法
EP4190780A4 (en) * 2020-08-25 2024-03-20 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. MUPIROCIN EXTRACTION PROCESS
US20240043888A1 (en) * 2021-02-07 2024-02-08 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Fermentation method for mupirocin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1395907A (en) 1971-06-12 1975-05-29 Beecham Group Ltd Antibiotics
JPS5270083A (en) 1975-12-04 1977-06-10 Yoshitomi Pharmaceut Ind Ltd Manufacture of an antibiotics, trans-pseudomonic acid
CA1103264A (en) * 1977-09-30 1981-06-16 Norman H. Rogers Purification of pseudomonic acid
CA1115699A (en) 1978-05-20 1982-01-05 Alan D. Curzons Lithium pseudomonate and its preparation
ZA923242B (en) * 1991-05-07 1993-01-27 Sankyo Co Novel anti-bacterial compound

Also Published As

Publication number Publication date
AU771214B2 (en) 2004-03-18
HUP0105286A3 (en) 2003-03-28
NO20013790L (no) 2001-10-02
BG105775A (bg) 2002-03-29
BR0009178A (pt) 2001-11-20
HRP20010570A2 (en) 2002-08-31
IL144678A0 (en) 2002-06-30
CZ20012725A3 (cs) 2002-03-13
IS6034A (is) 2001-08-01
YU55501A (sh) 2003-07-07
AU2980200A (en) 2000-08-25
KR20010112258A (ko) 2001-12-20
SK10902001A3 (sk) 2002-04-04
HUP0105286A2 (hu) 2002-05-29
EP1147210A4 (en) 2004-06-02
MXPA01007805A (es) 2003-06-04
CN1345377A (zh) 2002-04-17
US6245921B1 (en) 2001-06-12
WO2000046388A1 (en) 2000-08-10
EP1147210A1 (en) 2001-10-24
TR200102232T2 (tr) 2002-02-21
CA2360840A1 (en) 2000-08-10
JP2002535996A (ja) 2002-10-29
ZA200106057B (en) 2002-07-24
PL349153A1 (en) 2002-07-01
NO20013790D0 (no) 2001-08-02

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