JPS5270083A - Manufacture of an antibiotics, trans-pseudomonic acid - Google Patents

Manufacture of an antibiotics, trans-pseudomonic acid

Info

Publication number
JPS5270083A
JPS5270083A JP14535875A JP14535875A JPS5270083A JP S5270083 A JPS5270083 A JP S5270083A JP 14535875 A JP14535875 A JP 14535875A JP 14535875 A JP14535875 A JP 14535875A JP S5270083 A JPS5270083 A JP S5270083A
Authority
JP
Japan
Prior art keywords
trans
antibiotics
manufacture
pseudomonic acid
gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14535875A
Other languages
Japanese (ja)
Other versions
JPS5247037B2 (en
Inventor
Katsuyoshi Iimori
Takashi Ikeda
Hideo Matsuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP14535875A priority Critical patent/JPS5270083A/en
Publication of JPS5270083A publication Critical patent/JPS5270083A/en
Publication of JPS5247037B2 publication Critical patent/JPS5247037B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: Trans-Pseudomonic acid, a low toxicity antibiotics having germicidal activity upon gram-positive backteria and certain gram-negative bacteria and free from hemolysis and deactivation by the serum, is obtained by the culture of a specific microorganism in high selectivity.
COPYRIGHT: (C)1977,JPO&Japio
JP14535875A 1975-12-04 1975-12-04 Manufacture of an antibiotics, trans-pseudomonic acid Granted JPS5270083A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14535875A JPS5270083A (en) 1975-12-04 1975-12-04 Manufacture of an antibiotics, trans-pseudomonic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14535875A JPS5270083A (en) 1975-12-04 1975-12-04 Manufacture of an antibiotics, trans-pseudomonic acid

Publications (2)

Publication Number Publication Date
JPS5270083A true JPS5270083A (en) 1977-06-10
JPS5247037B2 JPS5247037B2 (en) 1977-11-29

Family

ID=15383335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14535875A Granted JPS5270083A (en) 1975-12-04 1975-12-04 Manufacture of an antibiotics, trans-pseudomonic acid

Country Status (1)

Country Link
JP (1) JPS5270083A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5352629A (en) * 1976-10-23 1978-05-13 Beecham Group Ltd Treating method of certain microbic infectious disease
JPS5459281A (en) * 1977-09-30 1979-05-12 Beecham Group Ltd Purification of pseudomonic acid
EP0005614A1 (en) * 1978-05-20 1979-11-28 Beecham Group Plc Lithium pseudomonate, process for its isolation and its hydrolysis
WO2000046389A1 (en) * 1999-02-03 2000-08-10 Biogal Gyogyszergyar Rt Process for the preparation of pseudomonic acid a antibiotic by microbiological method
US6245921B1 (en) 1999-02-03 2001-06-12 Biogal Gyogyszergyar Rt. Process for the isolation of pseudomonic acid A from pseudomonic acid complex-containing culture broth
WO2003000910A3 (en) * 2001-06-21 2003-04-24 Biogal Gyogyszergyar Metabolic controlled fermentation process for pseudomonic acid production
US7589128B2 (en) 2004-06-01 2009-09-15 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Process for preparation of amorphous form of a drug
US7737177B2 (en) 2001-12-28 2010-06-15 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság Processes for preparing crystalline and amorphous mupirocin calcium
CN103820369A (en) * 2014-03-07 2014-05-28 浙江瑞邦药业有限公司 Pseudomonas fluorescens and an application thereof
WO2022042299A1 (en) * 2020-08-25 2022-03-03 杭州中美华东制药有限公司 Method for extracting mupirocin

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5352629A (en) * 1976-10-23 1978-05-13 Beecham Group Ltd Treating method of certain microbic infectious disease
JPS6312043B2 (en) * 1976-10-23 1988-03-17 Beecham Group Plc
JPS5459281A (en) * 1977-09-30 1979-05-12 Beecham Group Ltd Purification of pseudomonic acid
JPH032867B2 (en) * 1977-09-30 1991-01-17 Sumisukurain Biichamu Plc
EP0005614A1 (en) * 1978-05-20 1979-11-28 Beecham Group Plc Lithium pseudomonate, process for its isolation and its hydrolysis
US6509177B1 (en) * 1999-02-03 2003-01-21 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid A antibiotic by microbiological method
US6245921B1 (en) 1999-02-03 2001-06-12 Biogal Gyogyszergyar Rt. Process for the isolation of pseudomonic acid A from pseudomonic acid complex-containing culture broth
US6506591B2 (en) * 1999-02-03 2003-01-14 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid a antibiotic by microbiological method
WO2000046389A1 (en) * 1999-02-03 2000-08-10 Biogal Gyogyszergyar Rt Process for the preparation of pseudomonic acid a antibiotic by microbiological method
US7078223B2 (en) 1999-02-03 2006-07-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Process for the preparation of pseudomonic acid a antibiotic by microbiological method
WO2003000910A3 (en) * 2001-06-21 2003-04-24 Biogal Gyogyszergyar Metabolic controlled fermentation process for pseudomonic acid production
US7439045B2 (en) 2001-06-21 2008-10-21 TEVA Gyógyszergyár Zártkörúen Müködö Részvénytársaság pH controlled fermentation process for pseudomonic acid production
US7737177B2 (en) 2001-12-28 2010-06-15 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság Processes for preparing crystalline and amorphous mupirocin calcium
US7589128B2 (en) 2004-06-01 2009-09-15 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Process for preparation of amorphous form of a drug
CN103820369A (en) * 2014-03-07 2014-05-28 浙江瑞邦药业有限公司 Pseudomonas fluorescens and an application thereof
CN103820369B (en) * 2014-03-07 2015-11-18 浙江瑞邦药业有限公司 A kind of pseudomonas fluorescens and application thereof
WO2022042299A1 (en) * 2020-08-25 2022-03-03 杭州中美华东制药有限公司 Method for extracting mupirocin
EP4190780A4 (en) * 2020-08-25 2024-03-20 Hangzhou Zhongmeihuadong Pharmaceutical Co Ltd Method for extracting mupirocin

Also Published As

Publication number Publication date
JPS5247037B2 (en) 1977-11-29

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