CN1345377A - 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 - Google Patents

从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 Download PDF

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Publication number
CN1345377A
CN1345377A CN00805537A CN00805537A CN1345377A CN 1345377 A CN1345377 A CN 1345377A CN 00805537 A CN00805537 A CN 00805537A CN 00805537 A CN00805537 A CN 00805537A CN 1345377 A CN1345377 A CN 1345377A
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CN
China
Prior art keywords
pseudomonic acid
extract
acid
isobutyl acetate
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00805537A
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English (en)
Chinese (zh)
Inventor
I·巴塔
A·特德斯
V·塞尔
C·绍博
E·纳吉尼埃阿韦
V·克里
D·列昂诺夫
I·朗
M·比德洛尼埃伊格洛伊
G·杰科维奇
J·萨拉特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt filed Critical Biogal Gyogyszergyar Rt
Publication of CN1345377A publication Critical patent/CN1345377A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN00805537A 1999-02-03 2000-02-03 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法 Pending CN1345377A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11844799P 1999-02-03 1999-02-03
US60/118,447 1999-02-03

Publications (1)

Publication Number Publication Date
CN1345377A true CN1345377A (zh) 2002-04-17

Family

ID=22378653

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00805537A Pending CN1345377A (zh) 1999-02-03 2000-02-03 从含假单胞菌酸复合体的培养液中分离假单胞菌酸a的方法

Country Status (23)

Country Link
US (1) US6245921B1 (https=)
EP (1) EP1147210A4 (https=)
JP (1) JP2002535996A (https=)
KR (1) KR20010112258A (https=)
CN (1) CN1345377A (https=)
AU (1) AU771214B2 (https=)
BG (1) BG105775A (https=)
BR (1) BR0009178A (https=)
CA (1) CA2360840A1 (https=)
CZ (1) CZ20012725A3 (https=)
HK (1) HK1041294A1 (https=)
HR (1) HRP20010570A2 (https=)
HU (1) HUP0105286A3 (https=)
IL (1) IL144678A0 (https=)
IS (1) IS6034A (https=)
MX (1) MXPA01007805A (https=)
NO (1) NO20013790L (https=)
PL (1) PL349153A1 (https=)
SK (1) SK10902001A3 (https=)
TR (1) TR200102232T2 (https=)
WO (1) WO2000046388A1 (https=)
YU (1) YU55501A (https=)
ZA (1) ZA200106057B (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124221B (zh) * 2005-02-21 2012-05-23 克利亚制药股份公司 莫匹罗星的提纯方法
CN103820369A (zh) * 2014-03-07 2014-05-28 浙江瑞邦药业有限公司 一种萤光假单胞菌及其应用
CN104370896A (zh) * 2013-11-29 2015-02-25 江苏汉邦科技有限公司 一种纯化假单孢菌素的方法
CN109053707A (zh) * 2018-09-19 2018-12-21 福建康鸿生物科技有限公司 一种莫匹罗星的提纯方法
CN110823649A (zh) * 2019-10-21 2020-02-21 河南中烟工业有限责任公司 一种卷烟主流烟气中有机酸的收集方法和检测方法
WO2022042299A1 (zh) * 2020-08-25 2022-03-03 杭州中美华东制药有限公司 一种莫匹罗星的提取方法
WO2022166459A1 (zh) * 2021-02-07 2022-08-11 杭州中美华东制药有限公司 一种莫匹罗星的发酵方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2360865A1 (en) 1999-02-03 2000-08-10 Biogal Gyogyszergyar Rt. Process for the preparation of pseudomonic acid a antibiotic by microbiological method
CZ200467A3 (cs) * 2001-06-21 2004-10-13 Biogalágyogyszergyarárt Metabolicky řízený způsob fermentace pro výrobu pseudomonové kyseliny
PL371263A1 (en) 2001-12-28 2005-06-13 Biogal Gyogyszergyar Rt Processes for preparing crystalline and amorphous mupirocin calcium
IL150907A (en) * 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
CA2560984A1 (en) * 2004-06-01 2005-12-15 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Process for preparation of amorphous form of a drug
GB2441328A (en) * 2006-08-30 2008-03-05 Alpharma Aps A method for obtaining mupirocin calcium
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1395907A (en) 1971-06-12 1975-05-29 Beecham Group Ltd Antibiotics
JPS5270083A (en) 1975-12-04 1977-06-10 Yoshitomi Pharmaceut Ind Ltd Manufacture of an antibiotics, trans-pseudomonic acid
CA1103264A (en) * 1977-09-30 1981-06-16 Norman H. Rogers Purification of pseudomonic acid
CA1115699A (en) 1978-05-20 1982-01-05 Alan D. Curzons Lithium pseudomonate and its preparation
ZA923242B (en) * 1991-05-07 1993-01-27 Sankyo Co Novel anti-bacterial compound

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124221B (zh) * 2005-02-21 2012-05-23 克利亚制药股份公司 莫匹罗星的提纯方法
CN104370896A (zh) * 2013-11-29 2015-02-25 江苏汉邦科技有限公司 一种纯化假单孢菌素的方法
CN103820369A (zh) * 2014-03-07 2014-05-28 浙江瑞邦药业有限公司 一种萤光假单胞菌及其应用
CN103820369B (zh) * 2014-03-07 2015-11-18 浙江瑞邦药业有限公司 一种萤光假单胞菌及其应用
CN109053707A (zh) * 2018-09-19 2018-12-21 福建康鸿生物科技有限公司 一种莫匹罗星的提纯方法
CN110823649A (zh) * 2019-10-21 2020-02-21 河南中烟工业有限责任公司 一种卷烟主流烟气中有机酸的收集方法和检测方法
WO2022042299A1 (zh) * 2020-08-25 2022-03-03 杭州中美华东制药有限公司 一种莫匹罗星的提取方法
CN116018342A (zh) * 2020-08-25 2023-04-25 杭州中美华东制药有限公司 一种莫匹罗星的提取方法
US12559482B2 (en) 2020-08-25 2026-02-24 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd Method for extracting mupirocin
WO2022166459A1 (zh) * 2021-02-07 2022-08-11 杭州中美华东制药有限公司 一种莫匹罗星的发酵方法

Also Published As

Publication number Publication date
AU771214B2 (en) 2004-03-18
HUP0105286A3 (en) 2003-03-28
NO20013790L (no) 2001-10-02
BG105775A (bg) 2002-03-29
BR0009178A (pt) 2001-11-20
HRP20010570A2 (en) 2002-08-31
IL144678A0 (en) 2002-06-30
CZ20012725A3 (cs) 2002-03-13
IS6034A (is) 2001-08-01
HK1041294A1 (zh) 2002-07-05
YU55501A (sh) 2003-07-07
AU2980200A (en) 2000-08-25
KR20010112258A (ko) 2001-12-20
SK10902001A3 (sk) 2002-04-04
HUP0105286A2 (hu) 2002-05-29
EP1147210A4 (en) 2004-06-02
MXPA01007805A (es) 2003-06-04
US6245921B1 (en) 2001-06-12
WO2000046388A1 (en) 2000-08-10
EP1147210A1 (en) 2001-10-24
TR200102232T2 (tr) 2002-02-21
CA2360840A1 (en) 2000-08-10
JP2002535996A (ja) 2002-10-29
ZA200106057B (en) 2002-07-24
PL349153A1 (en) 2002-07-01
NO20013790D0 (no) 2001-08-02

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