HRP20000792B1 - Platinum complex, its preparation and therapeutic application - Google Patents

Platinum complex, its preparation and therapeutic application

Info

Publication number
HRP20000792B1
HRP20000792B1 HR20000792A HRP20000792A HRP20000792B1 HR P20000792 B1 HRP20000792 B1 HR P20000792B1 HR 20000792 A HR20000792 A HR 20000792A HR P20000792 A HRP20000792 A HR P20000792A HR P20000792 B1 HRP20000792 B1 HR P20000792B1
Authority
HR
Croatia
Prior art keywords
platinum complex
preparation
therapeutic application
carbon atoms
group
Prior art date
Application number
HR20000792A
Other languages
English (en)
Inventor
�ak Franti�ek
Mistr Adolf
Poulova Anna
Melka Milan
Turanek Jaroslav
Zaluska Dana
Original Assignee
Pliva-Lachema A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Lachema A.S. filed Critical Pliva-Lachema A.S.
Publication of HRP20000792A2 publication Critical patent/HRP20000792A2/hr
Publication of HRP20000792B1 publication Critical patent/HRP20000792B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Kompleks platine s oksidacijskim brojem II formule (I), naznačen time, da X predstavlja halogeni atom, teA predstavlja -NH2-R skupinu, u kojoj je R triciklična ugljikovodična struktura koja sadržava od 10 do 14 ugljikovih atoma, koja, po izboru, može biti supstituirana s jednom ili dvije alkilne skupine na tricikličnom prstenu, pri čemu svaka skupina ima od 1 do 4 ugljikova atoma. Patent sadrži još 7 patentnih zahtjeva.
HR20000792A 1998-05-27 2000-11-17 Platinum complex, its preparation and therapeutic application HRP20000792B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ19981627A CZ288406B6 (en) 1998-05-27 1998-05-27 Platinum complex of oxidation number II, process for preparing such complex, the complex functioning as medicament and pharmaceutical composition in which the complex is comprised
PCT/CZ1999/000014 WO1999061450A1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application

Publications (2)

Publication Number Publication Date
HRP20000792A2 HRP20000792A2 (en) 2001-02-28
HRP20000792B1 true HRP20000792B1 (en) 2006-07-31

Family

ID=5463561

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000792A HRP20000792B1 (en) 1998-05-27 2000-11-17 Platinum complex, its preparation and therapeutic application

Country Status (21)

Country Link
US (1) US6350737B1 (hr)
EP (1) EP1082329B1 (hr)
JP (1) JP3647748B2 (hr)
CN (1) CN1124278C (hr)
AU (1) AU741381B2 (hr)
BG (1) BG64598B1 (hr)
BR (1) BR9910668A (hr)
CA (1) CA2331464C (hr)
CZ (1) CZ288406B6 (hr)
DE (1) DE69905714T2 (hr)
ES (1) ES2194457T3 (hr)
HR (1) HRP20000792B1 (hr)
HU (1) HU228940B1 (hr)
IL (1) IL139528A (hr)
NO (1) NO328940B1 (hr)
PL (1) PL191131B1 (hr)
RS (1) RS49739B (hr)
RU (1) RU2203901C2 (hr)
SK (1) SK284398B6 (hr)
UA (1) UA56314C2 (hr)
WO (1) WO1999061450A1 (hr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102312A1 (en) * 2004-04-27 2005-11-03 Mayne Pharma Limited Concentrated oxaliplatin solutions
CA2584493A1 (en) 2004-06-18 2006-01-05 Gpc Biotech, Inc. Kinase inhibitors for treating cancers
JP2008506463A (ja) * 2004-07-14 2008-03-06 ゲーペーツェー ビオテック アーゲー 可変投与量パッケージシステム
CZ2004964A3 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
US20120238488A1 (en) 2009-09-08 2012-09-20 Konstantinos Alevizopoulos Compounds and methods for treating neoplasia
PL3127544T3 (pl) * 2014-04-04 2022-01-03 Taiho Pharmaceutical Co., Ltd. Lek przeciwnowotworowy zawierający przeciwnowotworowy kompleks platyny i wzmacniacz działania przeciwnowotworowego
CN104922688A (zh) * 2015-02-10 2015-09-23 昆明贵研药业有限公司 奥沙利铂的环糊精复合物及制备方法
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2060615B (en) * 1979-08-23 1983-06-22 Johnson Matthey Co Ltd Platinum-amine complexes
US4902797A (en) * 1986-12-18 1990-02-20 Shionogi & Co., Ltd. Ammine-alicyclic amine-platinum complexes and antitumor agents
US5225207A (en) * 1989-03-17 1993-07-06 Laboratoire Roger Bellon Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds

Also Published As

Publication number Publication date
CN1124278C (zh) 2003-10-15
HUP0201762A2 (en) 2002-09-28
DE69905714D1 (de) 2003-04-10
HU228940B1 (en) 2013-07-29
EP1082329B1 (en) 2003-03-05
PL191131B1 (pl) 2006-03-31
PL344345A1 (en) 2001-11-05
BR9910668A (pt) 2001-01-30
CA2331464C (en) 2005-10-18
RU2203901C2 (ru) 2003-05-10
YU72000A (sh) 2002-10-18
IL139528A0 (en) 2001-11-25
HRP20000792A2 (en) 2001-02-28
NO20005919D0 (no) 2000-11-23
CA2331464A1 (en) 1999-12-02
RS49739B (sr) 2008-04-04
SK17742000A3 (sk) 2001-05-10
EP1082329A1 (en) 2001-03-14
NO20005919L (no) 2000-11-23
US6350737B1 (en) 2002-02-26
JP3647748B2 (ja) 2005-05-18
JP2002516331A (ja) 2002-06-04
WO1999061450A1 (en) 1999-12-02
HUP0201762A3 (en) 2004-03-01
ES2194457T3 (es) 2003-11-16
AU741381B2 (en) 2001-11-29
SK284398B6 (sk) 2005-03-04
CZ288406B6 (en) 2001-06-13
CZ162798A3 (cs) 1999-12-15
IL139528A (en) 2004-06-20
DE69905714T2 (de) 2003-11-13
CN1303387A (zh) 2001-07-11
BG64598B1 (bg) 2005-08-31
UA56314C2 (uk) 2003-05-15
BG104971A (en) 2001-08-31
NO328940B1 (no) 2010-06-21
AU3809299A (en) 1999-12-13

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Payment date: 20110420

Year of fee payment: 13

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