YU122290A - Jedinjenja indenoindola i - Google Patents

Jedinjenja indenoindola i

Info

Publication number
YU122290A
YU122290A YU122290A YU122290A YU122290A YU 122290 A YU122290 A YU 122290A YU 122290 A YU122290 A YU 122290A YU 122290 A YU122290 A YU 122290A YU 122290 A YU122290 A YU 122290A
Authority
YU
Yugoslavia
Prior art keywords
hydrogen
lower alkyl
alkyl group
compounds
formula
Prior art date
Application number
YU122290A
Other languages
English (en)
Inventor
M. Sainsbury
H.G. Shertzer
Original Assignee
University Of Bath Of School Of Chemistory Claverton Down
University Of Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Bath Of School Of Chemistory Claverton Down, University Of Cincinnati filed Critical University Of Bath Of School Of Chemistory Claverton Down
Publication of YU122290A publication Critical patent/YU122290A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

JEDINJENJA INDENOINDOLA I. Jedinjenja formule gde je R vodonik ili niža alkil grupa, R1 i R2 su nezavisno odabrani od vodonika ili niže alkil grupe, R3, R4 i R6 su nezavisno odabrani od vodonika, halogena ili niže alkil grupe, R5 je vodonik, hidroksi, halogen, niža alkil grupa, niža alkoksi grupa, mono- ili di-niža alkilamino grupa, NH2 ili NR11COR12, R7, R8, R9 i R10 su nezavisno odabrani od vodonika, hidroksi, niže alkil grupe, niže alkoksi grupe, mono- ili di-niže alkil-amino grupe, NH2 ili NR11COR12, R11 je vodonik ili niža alkil grupa, R12 je niža alkil grupa, pod uslovom da kada je R vodonik najmanje jedan od supstituenata R1 do R10 nije vodonik, ili njihova so, su korisna kao antioksidansi, unutar medicinske i ne-medicinske oblasti, i kada je R vodonik, metil ili neopentil u formuli IA, tada najmanje jedan od R1 do R10 nije vodonik. Mnoga jedinjenja formule IA i IB su nova i opisani su mnogi postupci za njihovo dobijanje.
YU122290A 1989-06-22 1990-06-22 Jedinjenja indenoindola i YU122290A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902273A SE8902273D0 (sv) 1989-06-22 1989-06-22 Indenoindole compounds i

Publications (1)

Publication Number Publication Date
YU122290A true YU122290A (sh) 1992-09-07

Family

ID=20376369

Family Applications (1)

Application Number Title Priority Date Filing Date
YU122290A YU122290A (sh) 1989-06-22 1990-06-22 Jedinjenja indenoindola i

Country Status (27)

Country Link
US (1) US5185360A (sh)
EP (1) EP0404536A1 (sh)
JP (1) JPH04506515A (sh)
KR (1) KR920702680A (sh)
CN (1) CN1049156A (sh)
AU (1) AU644082B2 (sh)
BG (1) BG60647B1 (sh)
CA (1) CA2062830A1 (sh)
DD (1) DD298388A5 (sh)
FI (1) FI915998A0 (sh)
HR (1) HRP920897A2 (sh)
HU (1) HUT59096A (sh)
IE (1) IE902246A1 (sh)
IL (1) IL94829A0 (sh)
IS (1) IS3589A7 (sh)
JO (2) JO1622B1 (sh)
LT (1) LTIP911A (sh)
MX (1) MX21243A (sh)
NO (1) NO915050L (sh)
NZ (1) NZ234174A (sh)
PL (1) PL166155B1 (sh)
PT (1) PT94467A (sh)
SE (1) SE8902273D0 (sh)
TW (1) TW198025B (sh)
WO (1) WO1990015800A1 (sh)
YU (1) YU122290A (sh)
ZA (1) ZA904826B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202736D0 (sv) * 1992-09-22 1992-09-22 Asea Brown Boveri Elektrisk ledare med isolering
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
FR2720064B1 (fr) * 1994-05-19 1996-06-28 Adir Thiacycloalkyl [b] indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CA2128283A1 (fr) * 1993-07-20 1995-01-21 Paul Caubere (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6069153A (en) * 1998-05-12 2000-05-30 American Home Products Corporation Indenoindoles and benzocarbazoles as estrogenic agents
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
EP1135393A2 (en) * 1998-12-04 2001-09-26 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10210623A1 (de) 2002-03-11 2003-09-25 Haarmann & Reimer Gmbh Alkoxy-substituierte Indane und deren Herstellung
CA2612442A1 (en) * 2005-07-14 2007-01-18 Irm Llc Heterotetracyclic compounds as tpo mimetics
CN105745301B (zh) * 2013-11-20 2020-04-21 东进世美肯株式会社 新型发光化合物以及包含其的有机发光元件

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3478208A (en) * 1967-01-04 1969-11-11 Atomic Energy Commission 2-aryl indoles and methods for their use
US3714148A (en) * 1968-10-15 1973-01-30 Sumitomo Chemical Co Process for preparing dibenzazocine derivatives and salts thereof
JPS6256471A (ja) * 1985-09-05 1987-03-12 Teikoku Hormone Mfg Co Ltd 含窒素四環式化合物

Also Published As

Publication number Publication date
DD298388A5 (de) 1992-02-20
IL94829A0 (en) 1991-04-15
PL285753A1 (en) 1991-03-25
IS3589A7 (is) 1990-12-23
HUT59096A (en) 1992-04-28
JO1629B1 (en) 1991-11-27
KR920702680A (ko) 1992-10-06
JPH04506515A (ja) 1992-11-12
CN1049156A (zh) 1991-02-13
NO915050D0 (no) 1991-12-20
US5185360A (en) 1993-02-09
MX21243A (es) 1994-01-31
NO915050L (no) 1992-02-21
AU5829990A (en) 1991-01-08
AU644082B2 (en) 1993-12-02
IE902246L (en) 1990-12-22
CA2062830A1 (en) 1990-12-23
HU904780D0 (en) 1992-03-30
FI915998A0 (fi) 1991-12-19
JO1622B1 (en) 1991-11-27
PL166155B1 (pl) 1995-04-28
ZA904826B (en) 1991-04-24
SE8902273D0 (sv) 1989-06-22
HRP920897A2 (hr) 1994-04-30
WO1990015800A1 (en) 1990-12-27
IE902246A1 (en) 1991-01-16
EP0404536A1 (en) 1990-12-27
NZ234174A (en) 1992-12-23
TW198025B (sh) 1993-01-11
LTIP911A (en) 1995-03-27
PT94467A (pt) 1991-02-08
BG60647B1 (bg) 1995-11-30

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