YU47099B - Postupak za dobijanje makrolidnih jedinjenja - Google Patents

Postupak za dobijanje makrolidnih jedinjenja

Info

Publication number
YU47099B
YU47099B YU239389A YU239389A YU47099B YU 47099 B YU47099 B YU 47099B YU 239389 A YU239389 A YU 239389A YU 239389 A YU239389 A YU 239389A YU 47099 B YU47099 B YU 47099B
Authority
YU
Yugoslavia
Prior art keywords
chem
compounds
procedure
preparation
components
Prior art date
Application number
YU239389A
Other languages
English (en)
Other versions
YU239389A (en
Inventor
L.D. Boeck
H. Chio
T.E. Eaton
Jr.O.W. Godfrey
K.H. Michel
W.M. Nakatsukasa
R.C.F. Yao
Original Assignee
Eli Lilly And Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co. filed Critical Eli Lilly And Co.
Publication of YU239389A publication Critical patent/YU239389A/xx
Publication of YU47099B publication Critical patent/YU47099B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Abstract

POSTUPAK ZA DOBIJANJE MAKROLIDNIH JEDINJENJA, insekticidna ili maticidna kompozicija, naznačena time, što obuhvata kao aktivan sastojak od 1 do 90% po masi A83543 jedinjenja formule 1: u kojoj R je H ili grupa odabrana od R2 je R1, R3, R5 i R6 su vodonik ili metil; R4 je metil ili etil; ili njihova fitološki prihvatljiva so kada se R razlikuje od vodonika; zajedno sa jednim ili više fitološki prihvatljivh nosača ili razblaživača. Prijava sadrži još 2 nezavisna i 5 zavisnih zahteva.
YU239389A 1988-12-19 1989-12-18 Postupak za dobijanje makrolidnih jedinjenja YU47099B (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28659188A 1988-12-19 1988-12-19
US42944189A 1989-10-30 1989-10-30

Publications (2)

Publication Number Publication Date
YU239389A YU239389A (en) 1991-04-30
YU47099B true YU47099B (sh) 1994-12-28

Family

ID=26963932

Family Applications (1)

Application Number Title Priority Date Filing Date
YU239389A YU47099B (sh) 1988-12-19 1989-12-18 Postupak za dobijanje makrolidnih jedinjenja

Country Status (32)

Country Link
US (2) US5496931A (sh)
EP (1) EP0375316B1 (sh)
JP (1) JP2535080B2 (sh)
KR (1) KR0143566B1 (sh)
CN (1) CN1035391C (sh)
AT (1) ATE116325T1 (sh)
AU (1) AU624458B2 (sh)
BG (1) BG60520B1 (sh)
BR (1) BR8906547A (sh)
CA (1) CA2005784C (sh)
CZ (1) CZ285992B6 (sh)
DE (2) DE68920301T2 (sh)
DK (1) DK174489B1 (sh)
DZ (1) DZ1375A1 (sh)
EG (1) EG19191A (sh)
ES (1) ES2065398T3 (sh)
FI (2) FI95601C (sh)
GR (1) GR3015598T3 (sh)
HU (1) HU208998B (sh)
IE (1) IE65919B1 (sh)
IL (1) IL92743A (sh)
IN (1) IN169756B (sh)
MA (1) MA21697A1 (sh)
MY (1) MY111148A (sh)
NL (1) NL350009I2 (sh)
NO (1) NO176914C (sh)
NZ (1) NZ231831A (sh)
OA (1) OA09249A (sh)
PE (1) PE5591A1 (sh)
PL (1) PL161476B1 (sh)
PT (1) PT92607B (sh)
YU (1) YU47099B (sh)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5539089A (en) * 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
TR28273A (tr) * 1992-12-09 1996-04-25 Dowelanco Yeni a83543 bilesikleri ve bunlari üretmeye mahsus yöntem.
AU685107B2 (en) * 1993-03-12 1998-01-15 Dow Agrosciences Llc New A83543 compounds and process for production thereof
BR9608380A (pt) * 1995-06-14 1999-01-05 Dowelanco Modificações sintéticas para os compostos de espinosina
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
GB9624501D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Insecticial compositions and method
NZ525907A (en) * 1997-12-23 2004-10-29 Syngenta Participations Ag Use of the macrolides abamectin, ememectin or spinosad for contolling molluscs
DE19823397B4 (de) * 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
DE19823396A1 (de) * 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
WO2000001347A2 (en) * 1998-07-02 2000-01-13 Eli Lilly And Company Formulations for controlling human lice
DE19857967A1 (de) * 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
NZ516787A (en) * 1999-08-12 2003-10-31 Lilly Co Eli Ectoparasiticidal aqueous suspension formulations of spinosyns
US6927210B1 (en) 1999-08-12 2005-08-09 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
US6933318B1 (en) 1999-08-12 2005-08-23 Eli Lilly And Company Topical organic ectoparasiticidal formulations
WO2001011961A1 (en) * 1999-08-12 2001-02-22 Eli Lilly And Company Control of ectoparasites using spinosyns
AU6606400A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Topical treatment for insect pests in companion animals
DE122011100022I1 (de) * 1999-08-12 2011-10-20 Lilly Co Eli Verwendung von Spinosad oder einer Zusammensetzungenthaltend spinosad.
CN1173988C (zh) * 1999-09-13 2004-11-03 道农业科学公司 杀虫剂大环内酯
AUPQ441699A0 (en) 1999-12-02 2000-01-06 Eli Lilly And Company Pour-on formulations
AUPQ634300A0 (en) * 2000-03-20 2000-04-15 Eli Lilly And Company Synergistic formulations
DE10013914A1 (de) 2000-03-21 2001-09-27 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6682925B1 (en) * 2000-04-13 2004-01-27 Agraquest, Inc. Streptomyces strain with insecticidal activity and method of using as an insecticide
DE10055941A1 (de) * 2000-11-10 2002-05-23 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6585990B1 (en) 2001-03-05 2003-07-01 Dow Agrosciences, Llc Compositions and devices using a spinosyn compound for control of insects
CN1310935C (zh) * 2001-03-21 2007-04-18 道农业科学公司 杀虫性多杀菌素衍生物
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
WO2002079184A1 (de) * 2001-03-29 2002-10-10 Bayer Cropscience Ag Zwischenverbindungen zur herstellung von spinosynen
US6727228B2 (en) * 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
US20090227452A1 (en) * 2001-09-14 2009-09-10 Birthisel Timothy D Spent fermented grain soil additive
KR20040045440A (ko) 2001-09-17 2004-06-01 일라이 릴리 앤드 캄파니 농약 배합물
US20040248824A1 (en) * 2001-10-08 2004-12-09 Snyder Daniel Earl Method for controlling beetles
TWI330183B (sh) * 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
MXPA04008071A (es) 2002-02-19 2004-11-26 Dow Agrosciences Llc Nuevas sintasas de poliquetida que producen espinosina.
DE10248257A1 (de) * 2002-10-16 2004-04-29 Bayer Cropscience Ag Wirkstoffkombinationen im insektiziden und akariziden Eigenschaften
DE10320505A1 (de) 2003-05-08 2004-11-25 Bayer Healthcare Ag Mittel zum Bekämpfen von Parasiten an Tieren
DE10333371A1 (de) * 2003-07-23 2005-02-10 Bayer Ag Fungizide Wirkstoffkombinationen
DE602004017347D1 (de) * 2003-11-04 2008-12-04 Intervet Int Bv Azol-pestiziden
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
US7879809B2 (en) * 2005-05-26 2011-02-01 Eli Lilly And Company Fish production
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
KR101404913B1 (ko) * 2006-05-25 2014-06-09 다우 아그로사이언시즈 엘엘씨 스피노신 훈증제
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2070416A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Verwendung von Wirkstoffkombinationen zur Bekämpfung von tierischen Schädlingen
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
PL2343975T3 (pl) 2008-09-22 2013-02-28 Entarco Sa Przeciwporostowe kompozycje spinozynu, metody ich stosowania i wyroby chronione przed przywieraniem bioorganizmów porostowych
EP2227951A1 (de) 2009-01-23 2010-09-15 Bayer CropScience AG Verwendung von Enaminocarbonylverbindungen zur Bekämpfung von durch Insekten übertragenen Viren
TW201041507A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041508A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041509A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041510A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
WO2010150100A1 (en) 2009-06-24 2010-12-29 Entarco Sa The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
KR20120090079A (ko) * 2009-11-06 2012-08-16 아그라퀘스트 인코퍼레이티드 방선균으로부터의 살충 발효 배지
NZ601290A (en) 2010-01-25 2014-04-30 Lilly Co Eli Methods for internally controlling or treating equine bot larvae
WO2011102550A1 (en) * 2010-02-19 2011-08-25 Sumitomo Chemical Company, Limited Pest control composition
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
CN103119152B (zh) 2010-05-11 2015-05-20 陶氏益农公司 Spnk菌株
CN102858870B (zh) 2010-09-29 2014-01-08 东海橡塑工业株式会社 水系软管用橡胶组合物和使用其得到的水系软管
BR112013010846A2 (pt) 2010-11-05 2016-07-12 Lilly Co Eli processos para inibir infestações de insetos
EP2654757A1 (en) 2010-12-22 2013-10-30 Entarco SA The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
CN103402357B (zh) 2010-12-29 2016-12-07 陶氏益农公司 防治昆虫的方法
EP2998399A1 (en) 2011-05-03 2016-03-23 Dow AgroSciences LLC Enhancing spinosyn production with oxygen binding proteins
JP5760781B2 (ja) 2011-07-13 2015-08-12 住友化学株式会社 有害節足動物防除組成物及び有害節足動物の防除方法
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
CN104168900A (zh) 2012-02-06 2014-11-26 梅里亚有限公司 包含全身性地起作用的活性剂的杀寄生虫口服兽用组合物、方法及其用途
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
US9895388B1 (en) * 2012-07-27 2018-02-20 ParaPRO Methods and compositions useful for controlling cutaneous mites
US20150250166A1 (en) 2012-08-23 2015-09-10 Allylix, Inc. Nootkatone as an insecticide and insect repellent
US9839214B2 (en) 2012-12-18 2017-12-12 Evolva, Inc. Solavetivone and 5-epi-beta-vertivone as pest repellants and pesticides
US10857121B2 (en) 2014-04-17 2020-12-08 Merial Inc. Use of malononitrile compounds for protecting animals from parasites
CN106536518B (zh) 2014-05-19 2020-05-12 勃林格殷格翰动物保健美国公司 驱蠕虫化合物
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10306887B2 (en) 2014-08-05 2019-06-04 The Board Of Regents Of The University Of Texas Systems Composition and methods for modulation of the octopamine receptor and its homologs
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
LT3298027T (lt) 2015-05-20 2021-08-10 Boehringer Ingelheim Animal Health USA Inc. Antihelmintiniai depsipeptido junginiai
CN106188184B (zh) * 2015-06-01 2021-01-05 中南大学 多杀菌素衍生物在制备抗肿瘤药物和抗kshv病毒药物方面的应用
ES2796379T3 (es) 2016-02-01 2020-11-26 Bayer Animal Health Gmbh Receptor nicotínico de acetilcolina de Rhipicephalus y plaguicida que actúa sobre el mismo
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
JP7350659B2 (ja) 2017-06-06 2023-09-26 ザイマージェン インコーポレイテッド Ｓａｃｃｈａｒｏｐｏｌｙｓｐｏｒａ ｓｐｉｎｏｓａの改良のためのハイスループット（ＨＴＰ）ゲノム操作プラットフォーム
US10494760B2 (en) 2017-12-12 2019-12-03 EctoGuard, LLC Methods and formulations for controlling human lice infestations
IL279977B1 (en) 2018-07-09 2024-02-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CA3107590A1 (en) 2018-07-27 2020-01-30 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
AU2020208145B2 (en) 2019-01-16 2023-02-02 Boehringer Ingelheim Vetmedica Gmbh Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
JP2022526901A (ja) 2019-03-19 2022-05-27 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物
US20220183291A1 (en) * 2019-04-17 2022-06-16 Boyce Thompson Institute For Plant Research, Inc. Compositions and methods for modulating immunity in plants
CA3183100A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelmintic heterocyclic compounds
CN113461757B (zh) * 2021-06-25 2023-08-22 湖州师范学院 新型十六元大环内酯的制备方法及用途
CN115785180A (zh) * 2022-12-19 2023-03-14 利民化学有限责任公司 作为杀虫剂的多杀菌素衍生物及其制备方法和应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881162A (en) * 1953-11-16 1959-04-07 Abbott Lab Recovery process
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US4206206A (en) * 1977-03-24 1980-06-03 Kowa Company, Ltd. Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4148883A (en) * 1977-08-18 1979-04-10 Pfizer Inc. Antibiotics produced by new species of nocardia
US4224314A (en) * 1979-03-02 1980-09-23 Pfizer Inc. Antibiotics produced by species of Nocardia
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体ｒｂｓ物質，その製法およびそれを有効成分とする抗腫瘍性剤
MX6021E (es) * 1979-09-12 1984-09-24 Lilly Co Eli Dispositivo para administrar compuestos farmaceuticos de liberacion controlada a los rumiantes cuando es retenido en la porcion reticular del estomago de los mismos
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4251511A (en) * 1979-10-02 1981-02-17 The Upjohn Company Antibiotic and fermentation process of preparing
US4321329A (en) * 1979-10-02 1982-03-23 The Upjohn Company Saccharopolyspora culture
US4293651A (en) * 1979-10-02 1981-10-06 The Upjohn Company Process for producing antibiotic using saccharopolyspora
EP0043197A1 (en) * 1980-07-02 1982-01-06 Beecham Group Plc Beta-Lactam antibiotic, its preparation and use
EP0044477B1 (en) * 1980-07-15 1984-02-08 Kowa Company, Ltd. Process for production of antibiotics, and novel antibiotics produced thereby
US4448970A (en) * 1981-02-19 1984-05-15 The Upjohn Company Nargenicin derivatives
IT1195299B (it) * 1981-11-27 1988-10-12 Pierrel Spa Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici
GB2111495B (en) * 1981-12-08 1985-04-17 Toyo Jozo Kk Aminoglycoside antibiotics
JPS58189114A (ja) * 1982-04-30 1983-11-04 Ss Pharmaceut Co Ltd 抗潰瘍剤
US4508647A (en) * 1982-07-26 1985-04-02 Bristol-Myers Company Antitumor antibiotics BBM-2040A and BBM-2040B
IT1194181B (it) * 1983-03-30 1988-09-14 Erba Farmitalia Procedimento migliorato per la purificazione della tilosina
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production
US4560509A (en) * 1983-11-16 1985-12-24 Eli Lilly And Company Antibiotic A39079 factor S-1
JPS625990A (ja) * 1985-06-20 1987-01-12 Sumitomo Chem Co Ltd 抗生物質およびその製造方法
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5003056A (en) * 1987-12-24 1991-03-26 Nippon Kayaku Kabushiki Kaisha Antibiotic NK86-0279, process for production of the same and application of the same
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
BR9006982A (pt) * 1989-10-30 1991-12-24 Lilly Co Eli Processo de recuperacao de a83543
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法

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IE65919B1 (en) 1995-11-29
DE122007000053I2 (de) 2009-09-17
NO895096L (no) 1990-06-20
NO895096D0 (no) 1989-12-18
FI96224C (fi) 1996-05-27
FI95601B (fi) 1995-11-15
IL92743A0 (en) 1990-09-17
KR900009681A (ko) 1990-07-05
DK642089D0 (da) 1989-12-18
YU239389A (en) 1991-04-30
EP0375316A1 (en) 1990-06-27
JP2535080B2 (ja) 1996-09-18
DE68920301T2 (de) 1995-07-06
CA2005784A1 (en) 1990-06-19
AU4689189A (en) 1990-06-21
BG60520B1 (bg) 1995-07-28
PT92607A (pt) 1990-06-29
BR8906547A (pt) 1990-09-04
MY111148A (en) 1999-09-30
DK642089A (da) 1990-06-20
ES2065398T3 (es) 1995-02-16
US5496931A (en) 1996-03-05
CN1043742A (zh) 1990-07-11
KR0143566B1 (ko) 1998-07-15
PT92607B (pt) 1995-09-12
CN1035391C (zh) 1997-07-09
AU624458B2 (en) 1992-06-11
OA09249A (fr) 1992-06-30
US5571901A (en) 1996-11-05
FI96224B (fi) 1996-02-15
DZ1375A1 (fr) 2004-09-13
CA2005784C (en) 1999-02-02
FI95601C (fi) 1996-02-26
IE894068L (en) 1990-06-19
IN169756B (sh) 1991-12-21
IL92743A (en) 1994-10-21
HU208998B (en) 1994-02-28
NZ231831A (en) 1994-10-26
NO176914B (no) 1995-03-13
FI950946A (fi) 1995-03-01
NL350009I2 (nl) 2003-08-01
NO176914C (no) 1995-06-21
HUT52562A (en) 1990-07-28
PE5591A1 (es) 1991-02-15
DE68920301D1 (de) 1995-02-09
GR3015598T3 (en) 1995-06-30
DK174489B1 (da) 2003-04-14
HU896661D0 (sh) 1990-03-28
FI896053A0 (fi) 1989-12-18
FI950946A0 (fi) 1995-03-01
PL161476B1 (pl) 1993-06-30
EG19191A (en) 1994-09-29
CZ285992B6 (cs) 1999-12-15
CZ717089A3 (cs) 1999-08-11
ATE116325T1 (de) 1995-01-15
MA21697A1 (fr) 1990-07-01
JPH02223589A (ja) 1990-09-05
EP0375316B1 (en) 1994-12-28

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