CA2099569A1 - New a83543 compounds and process for production thereof - Google Patents
New a83543 compounds and process for production thereofInfo
- Publication number
- CA2099569A1 CA2099569A1 CA002099569A CA2099569A CA2099569A1 CA 2099569 A1 CA2099569 A1 CA 2099569A1 CA 002099569 A CA002099569 A CA 002099569A CA 2099569 A CA2099569 A CA 2099569A CA 2099569 A1 CA2099569 A1 CA 2099569A1
- Authority
- CA
- Canada
- Prior art keywords
- new
- components
- nrrl
- compounds
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Abstract
New A83543 components and salts thereof, and N-demethyl derivatives are useful for the control of insects and mites.
Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18719, NRRL 18720, NRRL
18723 are provided. Insecticidal and ectoparasiticidal compositions containing new A83~43 components are also provided.
Pseudoaglycones of Aare useful for the preparation of A83543 components.
Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18719, NRRL 18720, NRRL
18723 are provided. Insecticidal and ectoparasiticidal compositions containing new A83~43 components are also provided.
Pseudoaglycones of Aare useful for the preparation of A83543 components.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79028291A | 1991-11-08 | 1991-11-08 | |
US79061691A | 1991-11-08 | 1991-11-08 | |
US07/790,616 | 1991-11-08 | ||
US07/790,287 US5202242A (en) | 1991-11-08 | 1991-11-08 | A83543 compounds and processes for production thereof |
US07/790,282 | 1991-11-08 | ||
US07/790,287 | 1991-11-08 | ||
PCT/US1992/009684 WO1993009126A1 (en) | 1991-11-08 | 1992-11-09 | New a83543 compounds and process for production thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2099569A1 true CA2099569A1 (en) | 1993-05-09 |
CA2099569C CA2099569C (en) | 2004-05-11 |
Family
ID=27419873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002099569A Expired - Lifetime CA2099569C (en) | 1991-11-08 | 1992-11-09 | New a83543 compounds and process for production thereof |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0573628B1 (en) |
JP (1) | JP3797386B2 (en) |
CN (1) | CN1073483A (en) |
AU (1) | AU666900B2 (en) |
BR (1) | BR9205458A (en) |
CA (1) | CA2099569C (en) |
DE (1) | DE69228239T2 (en) |
ES (1) | ES2126605T3 (en) |
GR (1) | GR3029614T3 (en) |
MX (1) | MX9206433A (en) |
RU (1) | RU2165704C2 (en) |
WO (1) | WO1993009126A1 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA21697A1 (en) * | 1988-12-19 | 1990-07-01 | Dow Agrosciences Llc | MACROLIDE COMPOUNDS. |
US5591606A (en) * | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
CA2156194C (en) * | 1993-03-12 | 2008-01-08 | Jon S. Mynderse | New a83543 compounds and process for production thereof |
WO1997000265A1 (en) * | 1995-06-14 | 1997-01-03 | Dowelanco | Synthetic modification to spinosyn compounds |
US6001981A (en) * | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
DE19823397B4 (en) * | 1998-05-26 | 2011-07-28 | Bayer CropScience AG, 40789 | Use of spinosyns for use as soil insecticides |
DE19823396A1 (en) | 1998-05-26 | 1999-12-02 | Bayer Ag | Synergistic insecticidal mixtures |
BRPI9911795B8 (en) * | 1998-07-02 | 2021-05-25 | Elanco Us Inc | pediculicidal shampoo formulation for controlling pediculus humanus humanus, pediculus humanus capitas or pthius pubis in a human, pediculicidal hair conditioner formulation, antilouse lotion formulation and use of a spinosyn or salt thereof” |
AU6606400A (en) * | 1999-08-12 | 2001-03-13 | Eli Lilly And Company | Topical treatment for insect pests in companion animals |
DE60015161T2 (en) * | 1999-09-13 | 2006-02-02 | Dow Agrosciences Llc, Indianapolis | PESTICIDE MACROLIDE |
US6585990B1 (en) | 2001-03-05 | 2003-07-01 | Dow Agrosciences, Llc | Compositions and devices using a spinosyn compound for control of insects |
IL157974A0 (en) | 2001-03-21 | 2004-03-28 | Dow Agrosciences Llc | Pesticidal macrolides |
IL160619A0 (en) | 2001-09-17 | 2004-07-25 | Lilly Co Eli | Pesticidal formulations pesticidal formulations |
MXPA04008071A (en) * | 2002-02-19 | 2004-11-26 | Dow Agrosciences Llc | Novel spinosyn-producing polyketide synthases. |
KR101404913B1 (en) * | 2006-05-25 | 2014-06-09 | 다우 아그로사이언시즈 엘엘씨 | Spinosyn fumigants |
JP5315818B2 (en) | 2007-07-12 | 2013-10-16 | 住友化学株式会社 | Pest control composition |
CN101560477B (en) * | 2008-04-16 | 2012-04-25 | 上海医药工业研究院 | Culture medium for fermenting pleocidin producing bacteria |
DK2343975T3 (en) | 2008-09-22 | 2012-12-03 | Entarco Sa | Spinosyn antibacterial compositions, methods for their use, and articles protected from attachment of biofouling organisms |
US8268975B2 (en) | 2009-04-03 | 2012-09-18 | Dow Agrosciences Llc | Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions |
WO2010150100A1 (en) | 2009-06-24 | 2010-12-29 | Entarco Sa | The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer |
WO2011143291A1 (en) | 2010-05-11 | 2011-11-17 | Dow Agrosciences Llc | Spnk strains |
US20160184340A1 (en) | 2010-12-22 | 2016-06-30 | Christine Kritikou | The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents |
EP2520653B1 (en) | 2011-05-03 | 2017-03-29 | Dow AgroSciences LLC | Integration of genes into the chromosome of saccharopolyspora spinosa |
US9404107B2 (en) | 2011-05-03 | 2016-08-02 | Dow Agrosciences Llc | Integration of genes into the chromosome of Saccharopolyspora spinosa |
US8741603B2 (en) * | 2011-05-03 | 2014-06-03 | Agrigenetics Inc. | Enhancing spinosyn production with oxygen binding proteins |
US9631195B2 (en) | 2011-12-28 | 2017-04-25 | Dow Agrosciences Llc | Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa |
JP2014111571A (en) * | 2012-10-29 | 2014-06-19 | Sumitomo Chemical Co Ltd | Agrochemical granule |
CA3107590A1 (en) | 2018-07-27 | 2020-01-30 | Aperta Biosciences, Llc | Spinosyn formulations for treatment of demodex-induced ocular and facial conditions |
CN110734467B (en) * | 2019-09-10 | 2021-08-27 | 北大方正集团有限公司 | Method for extracting and purifying spinosad from fermentation liquor |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA21697A1 (en) * | 1988-12-19 | 1990-07-01 | Dow Agrosciences Llc | MACROLIDE COMPOUNDS. |
-
1992
- 1992-11-07 CN CN92114318A patent/CN1073483A/en active Pending
- 1992-11-09 JP JP50877593A patent/JP3797386B2/en not_active Expired - Lifetime
- 1992-11-09 AU AU31318/93A patent/AU666900B2/en not_active Expired
- 1992-11-09 EP EP92925146A patent/EP0573628B1/en not_active Expired - Lifetime
- 1992-11-09 DE DE69228239T patent/DE69228239T2/en not_active Expired - Lifetime
- 1992-11-09 MX MX9206433A patent/MX9206433A/en unknown
- 1992-11-09 CA CA002099569A patent/CA2099569C/en not_active Expired - Lifetime
- 1992-11-09 BR BR9205458A patent/BR9205458A/en not_active IP Right Cessation
- 1992-11-09 RU RU93058364/13A patent/RU2165704C2/en active
- 1992-11-09 WO PCT/US1992/009684 patent/WO1993009126A1/en active IP Right Grant
- 1992-11-09 ES ES92925146T patent/ES2126605T3/en not_active Expired - Lifetime
-
1999
- 1999-03-08 GR GR990400701T patent/GR3029614T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPH06506477A (en) | 1994-07-21 |
EP0573628B1 (en) | 1999-01-20 |
GR3029614T3 (en) | 1999-06-30 |
AU666900B2 (en) | 1996-02-29 |
CN1073483A (en) | 1993-06-23 |
ES2126605T3 (en) | 1999-04-01 |
JP3797386B2 (en) | 2006-07-19 |
DE69228239D1 (en) | 1999-03-04 |
AU3131893A (en) | 1993-06-07 |
CA2099569C (en) | 2004-05-11 |
MX9206433A (en) | 1993-05-01 |
WO1993009126A1 (en) | 1993-05-13 |
EP0573628A1 (en) | 1993-12-15 |
DE69228239T2 (en) | 1999-05-27 |
RU2165704C2 (en) | 2001-04-27 |
BR9205458A (en) | 1994-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |