PT92607A - Processo para a producao de compostos macrolidos - Google Patents

Processo para a producao de compostos macrolidos

Info

Publication number
PT92607A
PT92607A PT92607A PT9260789A PT92607A PT 92607 A PT92607 A PT 92607A PT 92607 A PT92607 A PT 92607A PT 9260789 A PT9260789 A PT 9260789A PT 92607 A PT92607 A PT 92607A
Authority
PT
Portugal
Prior art keywords
compounds
chem
components
macrolidate
production
Prior art date
Application number
PT92607A
Other languages
English (en)
Other versions
PT92607B (pt
Inventor
Laverne Dwaine Boeck
Hang Chio
Tom Edward Eaton
Otis Webster Godfrey Jr
Karl Heinz Michel
Walter Mitsuo Nakatsukasa
Raymond Che-Fong Yao
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT92607A publication Critical patent/PT92607A/pt
Publication of PT92607B publication Critical patent/PT92607B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Electrotherapy Devices (AREA)
PT92607A 1988-12-19 1989-12-18 Processo para a producao de compostos macrolidos PT92607B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28659188A 1988-12-19 1988-12-19
US42944189A 1989-10-30 1989-10-30

Publications (2)

Publication Number Publication Date
PT92607A true PT92607A (pt) 1990-06-29
PT92607B PT92607B (pt) 1995-09-12

Family

ID=26963932

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92607A PT92607B (pt) 1988-12-19 1989-12-18 Processo para a producao de compostos macrolidos

Country Status (32)

Country Link
US (2) US5496931A (pt)
EP (1) EP0375316B1 (pt)
JP (1) JP2535080B2 (pt)
KR (1) KR0143566B1 (pt)
CN (1) CN1035391C (pt)
AT (1) ATE116325T1 (pt)
AU (1) AU624458B2 (pt)
BG (1) BG60520B1 (pt)
BR (1) BR8906547A (pt)
CA (1) CA2005784C (pt)
CZ (1) CZ285992B6 (pt)
DE (2) DE122007000053I2 (pt)
DK (1) DK174489B1 (pt)
DZ (1) DZ1375A1 (pt)
EG (1) EG19191A (pt)
ES (1) ES2065398T3 (pt)
FI (2) FI95601C (pt)
GR (1) GR3015598T3 (pt)
HU (1) HU208998B (pt)
IE (1) IE65919B1 (pt)
IL (1) IL92743A (pt)
IN (1) IN169756B (pt)
MA (1) MA21697A1 (pt)
MY (1) MY111148A (pt)
NL (1) NL350009I2 (pt)
NO (1) NO176914C (pt)
NZ (1) NZ231831A (pt)
OA (1) OA09249A (pt)
PE (1) PE5591A1 (pt)
PL (1) PL161476B1 (pt)
PT (1) PT92607B (pt)
YU (1) YU47099B (pt)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
US5539089A (en) * 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
TR28273A (tr) * 1992-12-09 1996-04-25 Dowelanco Yeni a83543 bilesikleri ve bunlari üretmeye mahsus yöntem.
CA2156194C (en) * 1993-03-12 2008-01-08 Jon S. Mynderse New a83543 compounds and process for production thereof
CN1130369C (zh) * 1995-06-14 2003-12-10 道农业科学公司 对刺糖多孢菌素化合物的合成修饰
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
GB9624501D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Insecticial compositions and method
CN100527958C (zh) * 1997-12-23 2009-08-19 辛根塔参与股份公司 大环内酯在害虫防治中的应用
DE19823397B4 (de) * 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
DE19823396A1 (de) * 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
UA65624C2 (uk) * 1998-07-02 2004-04-15 Елі Ліллі Енд Компані Препарат для догляду за волоссям (варіанти) та спосіб боротьби з педикульозним ураженням людини із застосуванням спінозину (варіанти)
DE19857967A1 (de) * 1998-12-16 2000-06-21 Bayer Ag Wirkstoffkombinationen
MXPA02001504A (es) * 1999-08-12 2002-07-02 Lilly Co Eli Formulaciones de spinosyns de suspensiones acuosas edtoparasiticidas.
IL147828A0 (en) 1999-08-12 2002-08-14 Lilly Co Eli Oral treatment of companion animals with ectoparasiticidal spinosyns
US6933318B1 (en) 1999-08-12 2005-08-23 Eli Lilly And Company Topical organic ectoparasiticidal formulations
US6927210B1 (en) 1999-08-12 2005-08-09 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
AU6606400A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Topical treatment for insect pests in companion animals
AU6605300A (en) * 1999-08-12 2001-03-13 Eli Lilly And Company Control of ectoparasites using spinosyns
DE60015161T2 (de) * 1999-09-13 2006-02-02 Dow Agrosciences Llc, Indianapolis Pestizide makrolide
AUPQ441699A0 (en) 1999-12-02 2000-01-06 Eli Lilly And Company Pour-on formulations
AUPQ634300A0 (en) * 2000-03-20 2000-04-15 Eli Lilly And Company Synergistic formulations
DE10013914A1 (de) 2000-03-21 2001-09-27 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6682925B1 (en) * 2000-04-13 2004-01-27 Agraquest, Inc. Streptomyces strain with insecticidal activity and method of using as an insecticide
DE10055941A1 (de) 2000-11-10 2002-05-23 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6585990B1 (en) 2001-03-05 2003-07-01 Dow Agrosciences, Llc Compositions and devices using a spinosyn compound for control of insects
DK1373290T3 (da) * 2001-03-21 2014-12-01 Dow Agrosciences Llc Pesticidale spinosynderivater
TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
JP2004526742A (ja) * 2001-03-29 2004-09-02 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト スピノシン類を製造するための中間体
US6727228B2 (en) * 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
DE10135550A1 (de) * 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
US20090227452A1 (en) * 2001-09-14 2009-09-10 Birthisel Timothy D Spent fermented grain soil additive
DK1435786T3 (da) * 2001-09-17 2011-10-03 Lilly Co Eli Pesticide formuleringer
JP2005504832A (ja) * 2001-10-08 2005-02-17 イーライ・リリー・アンド・カンパニー 甲虫を防除する方法
TWI330183B (pt) * 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
MXPA04008071A (es) 2002-02-19 2004-11-26 Dow Agrosciences Llc Nuevas sintasas de poliquetida que producen espinosina.
DE10248257A1 (de) * 2002-10-16 2004-04-29 Bayer Cropscience Ag Wirkstoffkombinationen im insektiziden und akariziden Eigenschaften
DE10320505A1 (de) 2003-05-08 2004-11-25 Bayer Healthcare Ag Mittel zum Bekämpfen von Parasiten an Tieren
DE10333371A1 (de) * 2003-07-23 2005-02-10 Bayer Ag Fungizide Wirkstoffkombinationen
EP1682118B1 (en) * 2003-11-04 2008-10-22 Intervet International BV Ectoparasiticidal formulations of spinosyns and azole pesticides
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
WO2006127322A2 (en) * 2005-05-26 2006-11-30 Eli Lilly And Company Improved fish production
EP1849363A1 (en) * 2006-03-09 2007-10-31 Cheminova A/S Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin
AU2007267952B2 (en) * 2006-05-25 2012-04-19 Corteva Agriscience Llc Spinosyn fumigants
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2070416A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Verwendung von Wirkstoffkombinationen zur Bekämpfung von tierischen Schädlingen
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
KR20110069118A (ko) * 2008-09-22 2011-06-22 크리스틴 크리티코우 스피노신 방오 조성물, 이의 사용 방법 및 생물 오손 유기체의 부착으로부터 보호된 물품
EP2227951A1 (de) 2009-01-23 2010-09-15 Bayer CropScience AG Verwendung von Enaminocarbonylverbindungen zur Bekämpfung von durch Insekten übertragenen Viren
TW201041507A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity and methods for preparing same
TW201041508A (en) * 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041510A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
TW201041509A (en) 2009-04-30 2010-12-01 Dow Agrosciences Llc Pesticide compositions exhibiting enhanced activity
EP2445506B1 (en) 2009-06-24 2014-12-31 Entarco SA The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
JP2013509865A (ja) * 2009-11-06 2013-03-21 アグラクエスト インコーポレイテッド 放線菌由来の殺虫性発酵ブロス
EP2528587B1 (en) * 2010-01-25 2015-03-18 Eli Lilly and Company Spinosyns for use in internally controlling or treating equine bot larvae
TWI513407B (zh) * 2010-02-19 2015-12-21 Sumitomo Chemical Co 害蟲控制組成物
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
BR112012028860A2 (pt) 2010-05-11 2020-09-01 Dow Agrosciences Llc cepas spnk.
WO2012043372A1 (ja) 2010-09-29 2012-04-05 東海ゴム工業株式会社 水系ホース用ゴム組成物およびそれを用いて得られる水系ホース
EP2635122A1 (en) 2010-11-05 2013-09-11 Eli Lilly and Company Methods for inhibiting insect infestations
US20160184340A1 (en) 2010-12-22 2016-06-30 Christine Kritikou The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
WO2012141754A2 (en) 2010-12-29 2012-10-18 Dow Agrosciences Llc Methods of controlling insects
ES2625504T3 (es) 2011-05-03 2017-07-19 Dow Agrosciences Llc Integración de genes en el cromosoma de Saccharopolyspora spinosa
JP5760781B2 (ja) 2011-07-13 2015-08-12 住友化学株式会社 有害節足動物防除組成物及び有害節足動物の防除方法
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
EP3216448B8 (en) 2012-02-06 2019-06-05 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
US9895388B1 (en) * 2012-07-27 2018-02-20 ParaPRO Methods and compositions useful for controlling cutaneous mites
WO2014031790A1 (en) 2012-08-23 2014-02-27 Allylix, Inc. Nootkatone as an insecticide and insect repellent
WO2014099821A2 (en) 2012-12-18 2014-06-26 Allylix, Inc. Solavetivone and 5-epi-beta-vertivone as pest repellants and pesticides
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
CA2952857A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
US10306887B2 (en) 2014-08-05 2019-06-04 The Board Of Regents Of The University Of Texas Systems Composition and methods for modulation of the octopamine receptor and its homologs
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
ES2916216T3 (es) 2015-05-20 2022-06-29 Boehringer Ingelheim Animal Health Usa Inc Compuestos de depsipéptidos antihelmínticos
CN106188184B (zh) * 2015-06-01 2021-01-05 中南大学 多杀菌素衍生物在制备抗肿瘤药物和抗kshv病毒药物方面的应用
EP3411395B1 (en) 2016-02-01 2020-04-15 Bayer Animal Health GmbH Rhipicephalus nicotinic acetylcholine receptor and pest control acting thereon
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2018226893A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa
US10494760B2 (en) 2017-12-12 2019-12-03 EctoGuard, LLC Methods and formulations for controlling human lice infestations
EP3820870A1 (en) 2018-07-09 2021-05-19 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
CA3107590A1 (en) 2018-07-27 2020-01-30 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020150032A1 (en) 2019-01-16 2020-07-23 Boehringer Ingelheim Animal Health USA Inc. Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
US20220183291A1 (en) * 2019-04-17 2022-06-16 Boyce Thompson Institute For Plant Research, Inc. Compositions and methods for modulating immunity in plants
JP2023528822A (ja) 2020-05-29 2023-07-06 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性複素環式化合物
CN113461757B (zh) * 2021-06-25 2023-08-22 湖州师范学院 新型十六元大环内酯的制备方法及用途
CN115785180A (zh) * 2022-12-19 2023-03-14 利民化学有限责任公司 作为杀虫剂的多杀菌素衍生物及其制备方法和应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881162A (en) * 1953-11-16 1959-04-07 Abbott Lab Recovery process
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US4206206A (en) * 1977-03-24 1980-06-03 Kowa Company, Ltd. Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4148883A (en) * 1977-08-18 1979-04-10 Pfizer Inc. Antibiotics produced by new species of nocardia
US4224314A (en) * 1979-03-02 1980-09-23 Pfizer Inc. Antibiotics produced by species of Nocardia
JPS5943929B2 (ja) * 1979-08-13 1984-10-25 サッポロビール株式会社 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
RO86519B (ro) * 1979-09-12 1985-03-31 Eli Lilly And Company Dispozitiv pentru rumegatoare
US4251511A (en) * 1979-10-02 1981-02-17 The Upjohn Company Antibiotic and fermentation process of preparing
US4293651A (en) * 1979-10-02 1981-10-06 The Upjohn Company Process for producing antibiotic using saccharopolyspora
US4321329A (en) * 1979-10-02 1982-03-23 The Upjohn Company Saccharopolyspora culture
EP0043197A1 (en) * 1980-07-02 1982-01-06 Beecham Group Plc Beta-Lactam antibiotic, its preparation and use
EP0044477B1 (en) * 1980-07-15 1984-02-08 Kowa Company, Ltd. Process for production of antibiotics, and novel antibiotics produced thereby
US4448970A (en) * 1981-02-19 1984-05-15 The Upjohn Company Nargenicin derivatives
IT1195299B (it) * 1981-11-27 1988-10-12 Pierrel Spa Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici
CH656622A5 (de) * 1981-12-08 1986-07-15 Toyo Jozo Kk Aminoglycosid-antibiotika saccharocine und deren herstellung.
JPS58189114A (ja) * 1982-04-30 1983-11-04 Ss Pharmaceut Co Ltd 抗潰瘍剤
US4508647A (en) * 1982-07-26 1985-04-02 Bristol-Myers Company Antitumor antibiotics BBM-2040A and BBM-2040B
IT1194181B (it) * 1983-03-30 1988-09-14 Erba Farmitalia Procedimento migliorato per la purificazione della tilosina
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production
US4560509A (en) * 1983-11-16 1985-12-24 Eli Lilly And Company Antibiotic A39079 factor S-1
JPS625990A (ja) * 1985-06-20 1987-01-12 Sumitomo Chem Co Ltd 抗生物質およびその製造方法
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5003056A (en) * 1987-12-24 1991-03-26 Nippon Kayaku Kabushiki Kaisha Antibiotic NK86-0279, process for production of the same and application of the same
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
MA21697A1 (fr) * 1988-12-19 1990-07-01 Dow Agrosciences Llc Composes de macrolides.
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
AU631693B2 (en) * 1989-10-30 1992-12-03 Eli Lilly And Company A83543 recovery process
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法

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DE122007000053I2 (de) 2009-09-17
BR8906547A (pt) 1990-09-04
DE68920301D1 (de) 1995-02-09
KR900009681A (ko) 1990-07-05
OA09249A (fr) 1992-06-30
EP0375316A1 (en) 1990-06-27
KR0143566B1 (ko) 1998-07-15
PT92607B (pt) 1995-09-12
CN1035391C (zh) 1997-07-09
PL161476B1 (pl) 1993-06-30
IL92743A0 (en) 1990-09-17
CZ717089A3 (cs) 1999-08-11
HU896661D0 (pt) 1990-03-28
HU208998B (en) 1994-02-28
FI95601B (fi) 1995-11-15
NO895096L (no) 1990-06-20
CZ285992B6 (cs) 1999-12-15
FI95601C (fi) 1996-02-26
DK174489B1 (da) 2003-04-14
NO176914C (no) 1995-06-21
IL92743A (en) 1994-10-21
PE5591A1 (es) 1991-02-15
DK642089D0 (da) 1989-12-18
FI950946A (fi) 1995-03-01
EG19191A (en) 1994-09-29
CA2005784C (en) 1999-02-02
HUT52562A (en) 1990-07-28
US5496931A (en) 1996-03-05
US5571901A (en) 1996-11-05
BG60520B1 (bg) 1995-07-28
IE65919B1 (en) 1995-11-29
NO895096D0 (no) 1989-12-18
FI950946A0 (fi) 1995-03-01
NL350009I2 (nl) 2003-08-01
DZ1375A1 (fr) 2004-09-13
FI96224C (fi) 1996-05-27
DE68920301T2 (de) 1995-07-06
AU624458B2 (en) 1992-06-11
CA2005784A1 (en) 1990-06-19
ATE116325T1 (de) 1995-01-15
NO176914B (no) 1995-03-13
FI96224B (fi) 1996-02-15
BG90678A (bg) 1993-12-24
ES2065398T3 (es) 1995-02-16
EP0375316B1 (en) 1994-12-28
IN169756B (pt) 1991-12-21
YU239389A (en) 1991-04-30
IE894068L (en) 1990-06-19
DK642089A (da) 1990-06-20
MA21697A1 (fr) 1990-07-01
FI896053A0 (fi) 1989-12-18
JPH02223589A (ja) 1990-09-05
NZ231831A (en) 1994-10-26
GR3015598T3 (en) 1995-06-30
CN1043742A (zh) 1990-07-11
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YU47099B (sh) 1994-12-28
AU4689189A (en) 1990-06-21

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