HK1217117A1 - 用於使 試劑穩定化的製劑和方法 - Google Patents

用於使 試劑穩定化的製劑和方法

Info

Publication number
HK1217117A1
HK1217117A1 HK16104897.8A HK16104897A HK1217117A1 HK 1217117 A1 HK1217117 A1 HK 1217117A1 HK 16104897 A HK16104897 A HK 16104897A HK 1217117 A1 HK1217117 A1 HK 1217117A1
Authority
HK
Hong Kong
Prior art keywords
pcr
formulations
stabilizing
methods
reagents
Prior art date
Application number
HK16104897.8A
Other languages
English (en)
Inventor
Scott E Whitney
Los Rios Stephanie De
Senait Ghirmai
Rolf Muller
Vasco Liberal
Steven P Wilkinson
Original Assignee
Biomatrica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomatrica Inc filed Critical Biomatrica Inc
Publication of HK1217117A1 publication Critical patent/HK1217117A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
HK16104897.8A 2012-12-20 2016-04-28 用於使 試劑穩定化的製劑和方法 HK1217117A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261740356P 2012-12-20 2012-12-20
PCT/US2013/077290 WO2014100755A2 (en) 2012-12-20 2013-12-20 Formulations and methods for stabilizing pcr reagents

Publications (1)

Publication Number Publication Date
HK1217117A1 true HK1217117A1 (zh) 2016-12-23

Family

ID=50979418

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16104897.8A HK1217117A1 (zh) 2012-12-20 2016-04-28 用於使 試劑穩定化的製劑和方法

Country Status (4)

Country Link
US (1) US9725703B2 (zh)
EP (2) EP3249054A1 (zh)
HK (1) HK1217117A1 (zh)
WO (1) WO2014100755A2 (zh)

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US8900856B2 (en) 2004-04-08 2014-12-02 Biomatrica, Inc. Integration of sample storage and sample management for life science
EP2598660B1 (en) 2010-07-26 2017-03-15 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
WO2014100755A2 (en) 2012-12-20 2014-06-26 Biomatrica, Inc. Formulations and methods for stabilizing pcr reagents
EP3154338B1 (en) 2014-06-10 2020-01-29 Biomatrica, INC. Stabilization of thrombocytes at ambient temperatures
CN107075544B (zh) * 2014-07-22 2021-01-29 生物辐射实验室股份有限公司 与聚合酶联用的缓冲液
CN107002063A (zh) * 2014-11-25 2017-08-01 生物辐射实验室股份有限公司 精氨酸提高聚合酶储存稳定性
EP4242628A3 (en) 2015-12-08 2023-11-08 Biomatrica, INC. Reduction of erythrocyte sedimentation rate
US20180363026A1 (en) * 2015-12-08 2018-12-20 Biomatrica, Inc. Stabilization of pcr reagents and assays
WO2019122200A1 (en) * 2017-12-22 2019-06-27 Thermo Fisher Scientific Baltics Uab Polymerase chain reaction composition comprising amines
CN109485915B (zh) * 2018-12-10 2021-03-02 怀化学院 用于聚乙烯醇加工的添加剂及其制备方法
CN109553904B (zh) * 2018-12-10 2021-07-20 怀化学院 具有羟乙基的季铵盐在聚乙烯醇加工中的应用
KR20210060954A (ko) * 2019-11-19 2021-05-27 윤창근 급속 dna 검출 방법

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