HK1223508A1 - 用於調節 甲基化的組合物和方法用於調節 甲基化的組合物和方法 - Google Patents
用於調節 甲基化的組合物和方法用於調節 甲基化的組合物和方法Info
- Publication number
- HK1223508A1 HK1223508A1 HK16111814.3A HK16111814A HK1223508A1 HK 1223508 A1 HK1223508 A1 HK 1223508A1 HK 16111814 A HK16111814 A HK 16111814A HK 1223508 A1 HK1223508 A1 HK 1223508A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dna
- compositions
- methods
- modulating
- methylation
- Prior art date
Links
- 230000007067 DNA methylation Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361867000P | 2013-08-16 | 2013-08-16 | |
PCT/US2014/051317 WO2015023967A2 (en) | 2013-08-16 | 2014-08-15 | Compositions and methods for modulating dna methylation |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1223508A1 true HK1223508A1 (zh) | 2017-08-04 |
Family
ID=52468818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16111814.3A HK1223508A1 (zh) | 2013-08-16 | 2016-10-13 | 用於調節 甲基化的組合物和方法用於調節 甲基化的組合物和方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20160199434A1 (zh) |
EP (1) | EP3032953A4 (zh) |
JP (1) | JP2016529257A (zh) |
KR (1) | KR20160046832A (zh) |
CN (1) | CN105979779A (zh) |
AU (1) | AU2014306496A1 (zh) |
CA (1) | CA2921005A1 (zh) |
HK (1) | HK1223508A1 (zh) |
IL (1) | IL244082A0 (zh) |
MX (1) | MX2016002014A (zh) |
RU (1) | RU2016109125A (zh) |
WO (1) | WO2015023967A2 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO2686520T3 (zh) | 2011-06-06 | 2018-03-17 | ||
DK3007695T3 (da) | 2013-06-13 | 2024-03-18 | Akebia Therapeutics Inc | Sammensætninger og fremgangsmåder til behandling af anæmi |
BR112017015852A2 (pt) | 2015-01-23 | 2018-03-27 | Akebia Therapeutics Inc | forma de cristal, sal hemicálcico, sal hemicálcico di-hidratado, sal monossódico hidratado, sal bissódico monoidratado, sal monossódico anidro e método para preparar o composto 1 |
EP3265582B1 (en) * | 2015-03-06 | 2021-07-28 | Vib Vzw | Markers for determining tumor hypoxia |
HRP20211862T1 (hr) | 2015-04-01 | 2022-03-04 | Akebia Therapeutics, Inc. | Pripravci za i postupci liječenja anemije |
CN108048529B (zh) * | 2017-12-28 | 2021-01-19 | 广州市金圻睿生物科技有限责任公司 | 一种可稳定保存的肺癌甲基化基因检测试剂盒的质控品及应用 |
JPWO2019182037A1 (ja) * | 2018-03-20 | 2021-03-11 | 国立大学法人東京工業大学 | 毒性が低減されたアンチセンスオリゴヌクレオチド |
CN108441561A (zh) * | 2018-04-19 | 2018-08-24 | 安徽达健医学科技有限公司 | 一种双重甲基化荧光定量pcr法用于膀胱癌早期筛查检测的试剂盒 |
AR114886A1 (es) | 2018-05-09 | 2020-10-28 | Akebia Therapeutics Inc | Proceso para preparar ácido 2-[[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino]acético |
CN116113421A (zh) * | 2020-05-14 | 2023-05-12 | 阿莱兹精准医疗公司 | 使用siRNA调节PRDM2/RIZ蛋白表达的癌症治疗 |
CN117965739A (zh) * | 2024-02-21 | 2024-05-03 | 中山大学附属第一医院 | 用于宫颈癌相关基因甲基化检测的标志物、引物组合及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL3026044T3 (pl) * | 2006-06-26 | 2019-04-30 | Akebia Therapeutics Inc | Inhibitory prolilo-hydroksylazy i sposoby ich użycia |
JP2014522410A (ja) * | 2011-06-06 | 2014-09-04 | アケビア セラピューティクス インコーポレイテッド | がん治療のための方法として低酸素誘導因子−2αを安定化するための、化合物および組成物 |
JP6050337B2 (ja) * | 2011-06-06 | 2016-12-21 | ネイションワイド チルドレンズ ホスピタル, インコーポレイテッド | プロテオミクスに基づく、慢性副鼻腔炎の診断用検出方法 |
US20130022974A1 (en) * | 2011-06-17 | 2013-01-24 | The Regents Of The University Of Michigan | Dna methylation profiles in cancer |
-
2014
- 2014-08-15 WO PCT/US2014/051317 patent/WO2015023967A2/en active Application Filing
- 2014-08-15 US US14/911,380 patent/US20160199434A1/en not_active Abandoned
- 2014-08-15 JP JP2016534872A patent/JP2016529257A/ja active Pending
- 2014-08-15 EP EP14835786.6A patent/EP3032953A4/en not_active Withdrawn
- 2014-08-15 RU RU2016109125A patent/RU2016109125A/ru not_active Application Discontinuation
- 2014-08-15 AU AU2014306496A patent/AU2014306496A1/en not_active Abandoned
- 2014-08-15 KR KR1020167006500A patent/KR20160046832A/ko not_active Application Discontinuation
- 2014-08-15 MX MX2016002014A patent/MX2016002014A/es unknown
- 2014-08-15 CN CN201480057009.4A patent/CN105979779A/zh active Pending
- 2014-08-15 CA CA2921005A patent/CA2921005A1/en not_active Abandoned
-
2016
- 2016-02-11 IL IL244082A patent/IL244082A0/en unknown
- 2016-10-13 HK HK16111814.3A patent/HK1223508A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
IL244082A0 (en) | 2016-04-21 |
US20160199434A1 (en) | 2016-07-14 |
CA2921005A1 (en) | 2015-02-19 |
MX2016002014A (es) | 2016-07-21 |
JP2016529257A (ja) | 2016-09-23 |
RU2016109125A3 (zh) | 2018-07-30 |
WO2015023967A2 (en) | 2015-02-19 |
WO2015023967A3 (en) | 2015-04-09 |
AU2014306496A1 (en) | 2016-03-03 |
RU2016109125A (ru) | 2017-09-22 |
KR20160046832A (ko) | 2016-04-29 |
CN105979779A (zh) | 2016-09-28 |
EP3032953A2 (en) | 2016-06-22 |
EP3032953A4 (en) | 2017-02-08 |
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