HK1149765A1 - Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents - Google Patents

Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents

Info

Publication number
HK1149765A1
HK1149765A1 HK11107839.7A HK11107839A HK1149765A1 HK 1149765 A1 HK1149765 A1 HK 1149765A1 HK 11107839 A HK11107839 A HK 11107839A HK 1149765 A1 HK1149765 A1 HK 1149765A1
Authority
HK
Hong Kong
Prior art keywords
maytansinoids
preparation
methods
binding agents
cell binding
Prior art date
Application number
HK11107839.7A
Other languages
English (en)
Chinese (zh)
Inventor
Ravi V J Chari
Wayne C Widdison
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25350107&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1149765(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of HK1149765A1 publication Critical patent/HK1149765A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK11107839.7A 2001-05-31 2004-05-10 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents HK1149765A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/867,598 US6441163B1 (en) 2001-05-31 2001-05-31 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents

Publications (1)

Publication Number Publication Date
HK1149765A1 true HK1149765A1 (en) 2011-10-14

Family

ID=25350107

Family Applications (2)

Application Number Title Priority Date Filing Date
HK04103250.5A HK1060355A1 (zh) 2001-05-31 2004-05-10 美登素類和細胞結合劑的細胞毒性偶聯物的製備方法
HK11107839.7A HK1149765A1 (en) 2001-05-31 2004-05-10 Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK04103250.5A HK1060355A1 (zh) 2001-05-31 2004-05-10 美登素類和細胞結合劑的細胞毒性偶聯物的製備方法

Country Status (12)

Country Link
US (2) US6441163B1 (fr)
EP (2) EP2348024B1 (fr)
JP (2) JP5190170B2 (fr)
AU (1) AU2002251880B2 (fr)
CA (1) CA2417858C (fr)
CY (2) CY1116855T1 (fr)
DK (2) DK1390370T3 (fr)
ES (2) ES2551233T3 (fr)
HK (2) HK1060355A1 (fr)
NZ (1) NZ523655A (fr)
PT (2) PT2348024E (fr)
WO (1) WO2002098883A1 (fr)

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