HK1057546A1 - Enantioselective synthesis of azetidinone intermediate compounds. - Google Patents

Enantioselective synthesis of azetidinone intermediate compounds.

Info

Publication number
HK1057546A1
HK1057546A1 HK04100111A HK04100111A HK1057546A1 HK 1057546 A1 HK1057546 A1 HK 1057546A1 HK 04100111 A HK04100111 A HK 04100111A HK 04100111 A HK04100111 A HK 04100111A HK 1057546 A1 HK1057546 A1 HK 1057546A1
Authority
HK
Hong Kong
Prior art keywords
intermediate compounds
enantioselective synthesis
azetidinone intermediate
azetidinone
compound
Prior art date
Application number
HK04100111A
Other languages
English (en)
Inventor
T K Thiruvengadam
Fu Xiaoyoung
Chou-Hon G Tann
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of HK1057546A1 publication Critical patent/HK1057546A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK04100111A 2001-03-28 2004-01-07 Enantioselective synthesis of azetidinone intermediate compounds. HK1057546A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27928801P 2001-03-28 2001-03-28
PCT/US2002/009123 WO2002079174A2 (en) 2001-03-28 2002-03-25 Enantioselective synthesis of azetidinone intermediate compounds

Publications (1)

Publication Number Publication Date
HK1057546A1 true HK1057546A1 (en) 2004-04-08

Family

ID=23068350

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04100111A HK1057546A1 (en) 2001-03-28 2004-01-07 Enantioselective synthesis of azetidinone intermediate compounds.

Country Status (29)

Country Link
US (1) US6627757B2 (sh)
EP (1) EP1373230B1 (sh)
JP (1) JP4145663B2 (sh)
KR (1) KR100590342B1 (sh)
CN (1) CN1275949C (sh)
AT (1) ATE305459T1 (sh)
AU (1) AU2002258605B2 (sh)
BG (1) BG66189B1 (sh)
BR (1) BRPI0208384B1 (sh)
CA (1) CA2442219C (sh)
CZ (1) CZ304929B6 (sh)
DE (1) DE60206365T2 (sh)
DK (1) DK1373230T3 (sh)
EA (1) EA006898B1 (sh)
EE (1) EE05453B1 (sh)
ES (1) ES2245733T3 (sh)
HK (1) HK1057546A1 (sh)
HR (1) HRP20030760B1 (sh)
HU (1) HU230229B1 (sh)
IL (2) IL157552A0 (sh)
MX (1) MXPA03008803A (sh)
NZ (1) NZ527852A (sh)
PL (1) PL205952B1 (sh)
RS (1) RS50386B (sh)
SI (1) SI1373230T1 (sh)
SK (1) SK287408B6 (sh)
UA (1) UA75644C2 (sh)
WO (1) WO2002079174A2 (sh)
ZA (1) ZA200306612B (sh)

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Also Published As

Publication number Publication date
WO2002079174A2 (en) 2002-10-10
ATE305459T1 (de) 2005-10-15
UA75644C2 (en) 2006-05-15
MXPA03008803A (es) 2004-02-18
EA006898B1 (ru) 2006-04-28
IL157552A (en) 2009-08-03
EE05453B1 (et) 2011-08-15
CZ304929B6 (cs) 2015-01-28
US6627757B2 (en) 2003-09-30
JP4145663B2 (ja) 2008-09-03
CN1500083A (zh) 2004-05-26
JP2004532210A (ja) 2004-10-21
CN1275949C (zh) 2006-09-20
CZ20032610A3 (en) 2004-03-17
ZA200306612B (en) 2004-10-12
BRPI0208384B1 (pt) 2016-05-31
DE60206365T2 (de) 2006-07-06
RS50386B (sr) 2009-12-31
BR0208384A (pt) 2004-06-15
EP1373230B1 (en) 2005-09-28
BG108168A (en) 2004-09-30
PL363864A1 (en) 2004-11-29
HU230229B1 (hu) 2015-10-28
PL205952B1 (pl) 2010-06-30
HUP0303526A2 (hu) 2004-01-28
YU74803A (sh) 2006-05-25
IL157552A0 (en) 2004-03-28
KR20030085573A (ko) 2003-11-05
EE200300464A (et) 2003-12-15
HUP0303526A3 (en) 2004-11-29
EA200300970A1 (ru) 2004-04-29
NZ527852A (en) 2005-03-24
HRP20030760B1 (en) 2011-07-31
BG66189B1 (bg) 2011-12-30
CA2442219A1 (en) 2002-10-10
WO2002079174A3 (en) 2003-02-27
DK1373230T3 (da) 2005-11-07
CA2442219C (en) 2007-09-11
SK287408B6 (sk) 2010-09-07
US20020193607A1 (en) 2002-12-19
HRP20030760A2 (en) 2004-08-31
KR100590342B1 (ko) 2006-06-15
DE60206365D1 (de) 2005-11-03
ES2245733T3 (es) 2006-01-16
EP1373230A2 (en) 2004-01-02
AU2002258605B2 (en) 2006-01-12
SK11862003A3 (sk) 2004-04-06
SI1373230T1 (sl) 2005-12-31

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Effective date: 20220324