GB2199829B - Peptide derivatives - Google Patents

Peptide derivatives

Info

Publication number
GB2199829B
GB2199829B GB8723737A GB8723737A GB2199829B GB 2199829 B GB2199829 B GB 2199829B GB 8723737 A GB8723737 A GB 8723737A GB 8723737 A GB8723737 A GB 8723737A GB 2199829 B GB2199829 B GB 2199829B
Authority
GB
United Kingdom
Prior art keywords
peptide derivatives
peptide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8723737A
Other languages
English (en)
Other versions
GB2199829A (en
GB8723737D0 (en
Inventor
Rainer Albert
Wilfired Bauer
Francois Cardinaux
Monika Mergler
Janos Pless
Walter Prikoszovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8723737D0 publication Critical patent/GB8723737D0/en
Publication of GB2199829A publication Critical patent/GB2199829A/en
Priority to GB9011637A priority Critical patent/GB2233652B/en
Application granted granted Critical
Publication of GB2199829B publication Critical patent/GB2199829B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
GB8723737A 1986-10-13 1987-10-09 Peptide derivatives Expired - Lifetime GB2199829B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9011637A GB2233652B (en) 1986-10-13 1990-05-24 Solid phase synthesis of peptide alcohols

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE3634826 1986-10-13
DE3634797 1986-10-13
DE3634825 1986-10-13
DE3712626 1987-04-14
CH315387 1987-08-17

Publications (3)

Publication Number Publication Date
GB8723737D0 GB8723737D0 (en) 1987-11-11
GB2199829A GB2199829A (en) 1988-07-20
GB2199829B true GB2199829B (en) 1991-04-17

Family

ID=27509117

Family Applications (2)

Application Number Title Priority Date Filing Date
GB8723737A Expired - Lifetime GB2199829B (en) 1986-10-13 1987-10-09 Peptide derivatives
GB8800537A Expired - Lifetime GB2199831B (en) 1986-10-13 1988-01-12 Peptide derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8800537A Expired - Lifetime GB2199831B (en) 1986-10-13 1988-01-12 Peptide derivatives

Country Status (23)

Country Link
US (1) US5656721A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPH0645639B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR960016861B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU617986B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE1003752A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1340985C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH680512A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3790635T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK174337B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2007418A6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI874495A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2609991A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB2199829B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR871567B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (3) HU906341D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE912442A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU87014A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL194729C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ222133A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL157156B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT85904B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (2) SE8703938L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1988002756A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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DE3845000C2 (de) * 1987-07-10 1998-11-19 Novartis Ag Anwendung von Octreotid zur Behandlung von Brustkrebs
AU632468B2 (en) * 1988-02-01 1993-01-07 Upjohn Company, The Renin inhibiting peptides with polar end groups
GB2218102B (en) * 1988-04-08 1992-09-16 Sandoz Ltd Calcitonin peptide derivatives
DE3910667A1 (de) * 1988-04-11 1989-10-19 Sandoz Ag Peptidderivate
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
FR2638968B1 (fr) * 1988-11-11 1994-10-07 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
US5753627A (en) * 1988-12-05 1998-05-19 Novartis Ag Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis
US5776894A (en) * 1988-12-05 1998-07-07 Novartis Ag Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors
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JP3896430B2 (ja) * 1996-07-15 2007-03-22 アークレイ株式会社 糖化アミノ化合物の製造方法
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Citations (1)

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Publication number Priority date Publication date Assignee Title
US4280953A (en) * 1979-11-08 1981-07-28 The Salk Institute For Biological Studies Glycosylated analogs of somatostatin

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US4254023A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Synthesis of peptide alcohols by the solid phase method
ATE2512T1 (de) * 1979-11-27 1983-03-15 Sandoz Ag Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung.
FR2522967B1 (fr) * 1982-03-15 1986-03-07 Anvar Conjugues d'haptenes et de muramyl-peptides, doues d'activite immunogene et compositions les contenant
US4444683A (en) * 1982-11-17 1984-04-24 University Of Utah Glycosylated insulin derivatives
US4483792A (en) * 1982-11-17 1984-11-20 Kim Wan S Glycosylated insulin derivatives
FR2546163B1 (fr) * 1983-05-16 1987-10-09 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
FR2548673B1 (fr) * 1983-07-05 1985-10-04 Essilor Int Polymeres supports de produits actifs relargables et leur procede de preparation
LU85269A1 (fr) * 1984-03-26 1985-10-14 Techland S A Composes nouveaux de somatostatine,procede pour leur synthese,preparation a usage veterinaire contenant lesdits composes et procede pour le traitement d'animaux
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US4280953A (en) * 1979-11-08 1981-07-28 The Salk Institute For Biological Studies Glycosylated analogs of somatostatin

Also Published As

Publication number Publication date
KR880005153A (ko) 1988-06-28
HU906341D0 (en) 1991-04-29
CA1340985C (en) 2000-05-09
SE9301172L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1900-01-01
KR960016861B1 (ko) 1996-12-23
DK174337B1 (da) 2002-12-16
GB2199829A (en) 1988-07-20
DK532787A (da) 1988-04-14
DE3790635T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-10-06
WO1988002756A3 (en) 1988-07-14
AU7956487A (en) 1988-04-14
HU906340D0 (en) 1991-04-29
GR871567B (en) 1988-02-16
ES2007418A6 (es) 1989-06-16
CH680512A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-09-15
GB2199831B (en) 1991-04-17
PT85904B (pt) 1990-08-31
NL194729C (nl) 2003-01-07
NL8702345A (nl) 1988-05-02
PT85904A (en) 1987-11-01
GB2199831A (en) 1988-07-20
PL268173A1 (en) 1988-09-01
FI874495A0 (fi) 1987-10-12
DK532787D0 (da) 1987-10-12
NZ222133A (en) 1993-02-25
SE9301172D0 (sv) 1993-04-07
US5656721A (en) 1997-08-12
AU8015091A (en) 1991-10-31
AU617986B2 (en) 1991-12-12
WO1988002756A2 (en) 1988-04-21
BE1003752A4 (fr) 1992-06-09
FI874495L (fi) 1988-04-14
SE8703938L (sv) 1988-04-14
JPS63101399A (ja) 1988-05-06
PL157156B1 (pl) 1992-05-29
HUT46710A (en) 1988-11-28
FI874495A7 (fi) 1988-04-14
FR2609991B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1995-03-10
GB8723737D0 (en) 1987-11-11
CH682632A5 (de) 1993-10-29
SE518630C2 (sv) 2002-11-05
JP2744910B2 (ja) 1998-04-28
IE912442L (en) 1988-04-13
IE912442A1 (en) 1992-02-12
AU634664B2 (en) 1993-02-25
SE8703938D0 (sv) 1987-10-12
FR2609991A1 (fr) 1988-07-29
JPH0645639B2 (ja) 1994-06-15
LU87014A1 (fr) 1988-05-03
NL194729B (nl) 2002-09-02
GB8800537D0 (en) 1988-02-10
JPH0314599A (ja) 1991-01-23
HU206890B (en) 1993-01-28

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