GB8927255D0 - Peptide derivatives - Google Patents

Peptide derivatives

Info

Publication number
GB8927255D0
GB8927255D0 GB898927255A GB8927255A GB8927255D0 GB 8927255 D0 GB8927255 D0 GB 8927255D0 GB 898927255 A GB898927255 A GB 898927255A GB 8927255 A GB8927255 A GB 8927255A GB 8927255 D0 GB8927255 D0 GB 8927255D0
Authority
GB
United Kingdom
Prior art keywords
peptide derivatives
peptide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB898927255A
Other versions
GB2225579B (en
GB2225579A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8927255D0 publication Critical patent/GB8927255D0/en
Publication of GB2225579A publication Critical patent/GB2225579A/en
Application granted granted Critical
Publication of GB2225579B publication Critical patent/GB2225579B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB8927255A 1988-12-05 1989-12-01 Detectable somatostatin analogues containing a chelating group Expired - Lifetime GB2225579B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
GB8927255D0 true GB8927255D0 (en) 1990-01-31
GB2225579A GB2225579A (en) 1990-06-06
GB2225579B GB2225579B (en) 1993-03-17

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8927255A Expired - Lifetime GB2225579B (en) 1988-12-05 1989-12-01 Detectable somatostatin analogues containing a chelating group

Country Status (24)

Country Link
JP (2) JP2726320B2 (en)
KR (1) KR0156541B1 (en)
AT (1) AT403476B (en)
AU (1) AU633859B2 (en)
BE (1) BE1002296A5 (en)
CA (1) CA2004532C (en)
CH (1) CH678329A5 (en)
DE (1) DE3991505B4 (en)
DK (1) DK175338B1 (en)
ES (1) ES2023533A6 (en)
FI (1) FI102540B1 (en)
FR (1) FR2639947B1 (en)
GB (1) GB2225579B (en)
HK (1) HK189995A (en)
HU (2) HUT53375A (en)
IE (1) IE62091B1 (en)
IL (1) IL92534A (en)
LU (1) LU87633A1 (en)
MY (1) MY106120A (en)
NL (1) NL194828C (en)
PT (1) PT92487B (en)
SA (1) SA96160495B1 (en)
SE (1) SE508799C2 (en)
WO (1) WO1990006949A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5833942A (en) 1992-06-23 1998-11-10 Diatide, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging and therapeutic uses
US5981477A (en) 1991-11-27 1999-11-09 Diatide, Inc. Peptide-metal chelate conjugates
US6017512A (en) 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
DE3845000C2 (en) * 1987-07-10 1998-11-19 Novartis Ag Compsn. contg. somatostatin analogues for treating breast cancer
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
ATE181240T1 (en) * 1991-02-08 1999-07-15 Biomeasure Inc USE OF SOMATOSTATIN ANALOGUE FOR THE TREATMENT OF MELANOMA
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
CA2102633A1 (en) * 1991-06-03 1992-12-04 Peter H. Cox Radiolabelled somatostatin derivatives, their preparation and use
ES2150916T3 (en) * 1991-08-29 2000-12-16 Mallinckrodt Medical Inc USE OF GENISTIC ACID OR GENTISILIC ALCOHOL TO STABILIZE RADIO-MARKED PEPTIDES AND PROTEINS.
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
ES2155447T3 (en) * 1992-01-03 2001-05-16 Rhomed Inc PHARMACEUTICAL APPLICATIONS OF METAL PEPTIDES-IONS.
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
ATE203417T1 (en) * 1992-02-05 2001-08-15 Mallinckrodt Inc RADIOACTIVE LABELED SOMATOSTATIN
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
EP0636032A1 (en) * 1992-03-25 1995-02-01 Mallinckrodt Medical, Inc. Method of intraoperatively detecting and locating tumoral tissues
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0683676A4 (en) * 1993-02-02 1998-09-30 Neorx Corp Directed biodistribution of small molecules.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
EP1099707A3 (en) * 1993-06-23 2002-01-09 Diatide, Inc. Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (en) 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalcohol peptide derivatives
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
DE19917713A1 (en) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Short-chain peptide-dye conjugates as contrast agents for optical diagnostics
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
CA2443273C (en) * 2001-04-23 2011-09-27 Mallinckrodt Inc. Tc and re labeled radioactive glycosylated octreotide derivatives
WO2005018682A2 (en) 2003-08-20 2005-03-03 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
BRPI0414512B8 (en) * 2003-09-17 2021-05-25 Board Of Regentes The Univ Of Texas System composition to reproduce images of a pancreas and use of this
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
WO2014081655A1 (en) 2012-11-21 2014-05-30 Serene Oncology, Llc Tin-1 17m comprising somatostatin receptor binding compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
DE3511206A1 (en) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Polypeptide derivatives, their preparation and pharmaceutical products which contain these polypeptide derivatives
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3522638A1 (en) * 1985-06-25 1987-01-08 Diamalt Ag NEW SOMATOSTATIN DERIVATIVES
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
AU593611B2 (en) * 1986-02-14 1990-02-15 Nihon Medi-Physics Co., Ltd. High molecular compounds having amino groups, and their utilization
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU206890B (en) * 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
CH679045A5 (en) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
FR2638968B1 (en) * 1988-11-11 1994-10-07 Sandoz Sa NEW THERAPEUTIC USE OF SOMATOSTATIN AND ITS ANALOGS AND DERIVATIVES

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981477A (en) 1991-11-27 1999-11-09 Diatide, Inc. Peptide-metal chelate conjugates
US5985241A (en) 1991-11-27 1999-11-16 Diatide, Inc. Peptide-metal chelate conjugate complexes
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5833942A (en) 1992-06-23 1998-11-10 Diatide, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US6241965B1 (en) 1993-07-21 2001-06-05 Diatide, Inc. Somatostatin derivatives and their radiolabelled products

Also Published As

Publication number Publication date
FR2639947B1 (en) 1995-04-21
KR0156541B1 (en) 1998-10-15
NL194828B (en) 2002-12-02
DK612689A (en) 1990-06-06
GB2225579B (en) 1993-03-17
GB2225579A (en) 1990-06-06
WO1990006949A2 (en) 1990-06-28
MY106120A (en) 1995-03-31
SE8904087D0 (en) 1989-12-04
FR2639947A1 (en) 1990-06-08
HU211468A9 (en) 1995-11-28
AT403476B (en) 1998-02-25
DE3991505B4 (en) 2006-04-20
IL92534A (en) 1994-06-24
HK189995A (en) 1995-12-29
KR900009697A (en) 1990-07-05
SE508799C2 (en) 1998-11-09
AU4587189A (en) 1990-06-14
JP2726320B2 (en) 1998-03-11
CA2004532C (en) 2000-02-22
CH678329A5 (en) 1991-08-30
BE1002296A5 (en) 1990-11-20
IE62091B1 (en) 1994-12-14
DK612689D0 (en) 1989-12-05
JPH02184698A (en) 1990-07-19
ES2023533A6 (en) 1992-01-16
ATA901789A (en) 1997-07-15
PT92487A (en) 1990-06-29
WO1990006949A3 (en) 1990-07-26
NL194828C (en) 2003-04-03
HU896359D0 (en) 1990-02-28
FI102540B (en) 1998-12-31
FI102540B1 (en) 1998-12-31
SE8904087L (en) 1991-06-05
JPH1095737A (en) 1998-04-14
FI895809A0 (en) 1989-12-04
HUT53375A (en) 1990-10-28
AU633859B2 (en) 1993-02-11
JP3686503B2 (en) 2005-08-24
NL8902981A (en) 1990-07-02
IE893866L (en) 1990-06-05
SA96160495B1 (en) 2006-08-23
DK175338B1 (en) 2004-08-30
CA2004532A1 (en) 1990-06-05
LU87633A1 (en) 1991-09-18
PT92487B (en) 1996-01-31

Similar Documents

Publication Publication Date Title
GB8927255D0 (en) Peptide derivatives
GB8907652D0 (en) Peptide derivatives
GB2199831B (en) Peptide derivatives
EG19385A (en) N-phenylpyrazol -4-yl-ether derivatives
ZA892269B (en) Peptides
GB8821077D0 (en) Peptides
ZA899167B (en) Peptides
GB8828098D0 (en) Peptides
GB8826452D0 (en) Peptide derivatives
GB8907902D0 (en) Peptide derivatives
ZA899285B (en) Peptide derivatives
GB8808442D0 (en) Peptide derivatives
GB8808277D0 (en) Peptide derivatives
GB8808441D0 (en) Peptide derivatives
GB8808444D0 (en) Peptide derivatives
GB8808528D0 (en) Peptide derivatives
GB9118452D0 (en) Peptide derivatives
ZA892570B (en) Peptides derivatives
GB9011637D0 (en) Peptide derivatives
IE892472L (en) Peptide derivatives
GB8906638D0 (en) Peptide derivatives
IE891038L (en) Peptide derivatives
IE891120L (en) Peptide derivatives
GB8803479D0 (en) Polypeptide derivatives
GB8701077D0 (en) Peptide derivatives

Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20091130