DK612689D0 - PEPTIDE DERIVATIVES - Google Patents

PEPTIDE DERIVATIVES

Info

Publication number
DK612689D0
DK612689D0 DK612689A DK612689A DK612689D0 DK 612689 D0 DK612689 D0 DK 612689D0 DK 612689 A DK612689 A DK 612689A DK 612689 A DK612689 A DK 612689A DK 612689 D0 DK612689 D0 DK 612689D0
Authority
DK
Denmark
Prior art keywords
peptide derivatives
peptide
derivatives
Prior art date
Application number
DK612689A
Other languages
Danish (da)
Other versions
DK612689A (en
DK175338B1 (en
Inventor
Rainer Albert
Eric P Krenning
Steven W J Lamberts
Janos Pless
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK612689D0 publication Critical patent/DK612689D0/en
Publication of DK612689A publication Critical patent/DK612689A/en
Application granted granted Critical
Publication of DK175338B1 publication Critical patent/DK175338B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198906126A 1988-12-05 1989-12-05 Somatostatin octapeptide, process for its preparation, pharmaceutical composition and package containing it DK175338B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB8828364 1988-12-05
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB8916115 1989-07-13
GB8916761 1989-07-21
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
DK612689D0 true DK612689D0 (en) 1989-12-05
DK612689A DK612689A (en) 1990-06-06
DK175338B1 DK175338B1 (en) 2004-08-30

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906126A DK175338B1 (en) 1988-12-05 1989-12-05 Somatostatin octapeptide, process for its preparation, pharmaceutical composition and package containing it

Country Status (24)

Country Link
JP (2) JP2726320B2 (en)
KR (1) KR0156541B1 (en)
AT (1) AT403476B (en)
AU (1) AU633859B2 (en)
BE (1) BE1002296A5 (en)
CA (1) CA2004532C (en)
CH (1) CH678329A5 (en)
DE (1) DE3991505B4 (en)
DK (1) DK175338B1 (en)
ES (1) ES2023533A6 (en)
FI (1) FI102540B1 (en)
FR (1) FR2639947B1 (en)
GB (1) GB2225579B (en)
HK (1) HK189995A (en)
HU (2) HUT53375A (en)
IE (1) IE62091B1 (en)
IL (1) IL92534A (en)
LU (1) LU87633A1 (en)
MY (1) MY106120A (en)
NL (1) NL194828C (en)
PT (1) PT92487B (en)
SA (1) SA96160495B1 (en)
SE (1) SE508799C2 (en)
WO (1) WO1990006949A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
DE3845000C2 (en) * 1987-07-10 1998-11-19 Novartis Ag Compsn. contg. somatostatin analogues for treating breast cancer
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
ATE181240T1 (en) * 1991-02-08 1999-07-15 Biomeasure Inc USE OF SOMATOSTATIN ANALOGUE FOR THE TREATMENT OF MELANOMA
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
CA2102633A1 (en) * 1991-06-03 1992-12-04 Peter H. Cox Radiolabelled somatostatin derivatives, their preparation and use
EP0600992B1 (en) * 1991-08-29 2000-09-20 Mallinckrodt Medical, Inc. Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
DE69231586T2 (en) * 1992-01-03 2001-07-19 Rhomed Inc PHARMACEUTICAL APPLICATIONS BASED ON PEPTIDE METAL IONS
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
CA2129033A1 (en) * 1992-02-05 1993-08-19 Leon Lyle Radiolabelled peptide compounds
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
CA2131315A1 (en) * 1992-03-25 1993-09-30 Geert J. Ensing Method of intraoperatively detecting and locating tumoral tissues
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
CA2113121A1 (en) * 1993-01-12 1994-07-13 Rainer Albert Peptides
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0683676A4 (en) * 1993-02-02 1998-09-30 Neorx Corp Directed biodistribution of small molecules.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
DE69426673T2 (en) * 1993-06-23 2001-09-20 Diatide Inc RADIO-MARKED SOMATOSTATIN DERIVATIVES FOR IMAGING AND THERAPEUTIC USE
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (en) * 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalcohol peptide derivatives
DE19917713A1 (en) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Short-chain peptide-dye conjugates as contrast agents for optical diagnostics
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
EP1381396B1 (en) * 2001-04-23 2009-04-01 Mallinckrodt Inc. Tc and re labeled radioactive glycosylated octreotide derivatives
WO2005018682A2 (en) 2003-08-20 2005-03-03 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
CN1867363B (en) * 2003-09-17 2010-05-12 得克萨斯大学体系董事会 Mechanism-based targeted pancreatic beta cell imaging and therapy
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
WO2014081655A1 (en) 2012-11-21 2014-05-30 Serene Oncology, Llc Tin-1 17m comprising somatostatin receptor binding compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3511206A1 (en) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Polypeptide derivatives, their preparation and pharmaceutical products which contain these polypeptide derivatives
DE3522638A1 (en) * 1985-06-25 1987-01-08 Diamalt Ag NEW SOMATOSTATIN DERIVATIVES
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
DK172629B1 (en) * 1986-02-14 1999-03-22 Nihon Mediphysics Co Ltd Reactive high molecular weight compounds with at least one free amino group, high molecular weight compounds combined with a physiological
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
CH679045A5 (en) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
FR2638968B1 (en) * 1988-11-11 1994-10-07 Sandoz Sa NEW THERAPEUTIC USE OF SOMATOSTATIN AND ITS ANALOGS AND DERIVATIVES

Also Published As

Publication number Publication date
SE508799C2 (en) 1998-11-09
HUT53375A (en) 1990-10-28
NL194828C (en) 2003-04-03
CH678329A5 (en) 1991-08-30
KR0156541B1 (en) 1998-10-15
KR900009697A (en) 1990-07-05
DK612689A (en) 1990-06-06
PT92487B (en) 1996-01-31
WO1990006949A2 (en) 1990-06-28
JP2726320B2 (en) 1998-03-11
FI102540B (en) 1998-12-31
IE893866L (en) 1990-06-05
GB2225579B (en) 1993-03-17
FI102540B1 (en) 1998-12-31
HU896359D0 (en) 1990-02-28
ES2023533A6 (en) 1992-01-16
JP3686503B2 (en) 2005-08-24
NL194828B (en) 2002-12-02
LU87633A1 (en) 1991-09-18
PT92487A (en) 1990-06-29
DE3991505B4 (en) 2006-04-20
AU4587189A (en) 1990-06-14
FI895809A0 (en) 1989-12-04
WO1990006949A3 (en) 1990-07-26
BE1002296A5 (en) 1990-11-20
ATA901789A (en) 1997-07-15
HU211468A9 (en) 1995-11-28
IE62091B1 (en) 1994-12-14
CA2004532A1 (en) 1990-06-05
HK189995A (en) 1995-12-29
GB8927255D0 (en) 1990-01-31
SE8904087D0 (en) 1989-12-04
AT403476B (en) 1998-02-25
FR2639947A1 (en) 1990-06-08
NL8902981A (en) 1990-07-02
AU633859B2 (en) 1993-02-11
MY106120A (en) 1995-03-31
IL92534A (en) 1994-06-24
DK175338B1 (en) 2004-08-30
JPH02184698A (en) 1990-07-19
SE8904087L (en) 1991-06-05
SA96160495B1 (en) 2006-08-23
JPH1095737A (en) 1998-04-14
FR2639947B1 (en) 1995-04-21
GB2225579A (en) 1990-06-06
CA2004532C (en) 2000-02-22

Similar Documents

Publication Publication Date Title
DK612689A (en) PEPTIDE DERIVATIVES
DK163689A (en) PEPTIDE DERIVATIVES
DK22588D0 (en) PEPTIDE DERIVATIVES
DK532787D0 (en) PEPTIDE DERIVATIVES
DK540289A (en) PROTEIN
DK149889A (en) sweetener
DE68925161D1 (en) Alkylavermectin derivatives
DE68927948D1 (en) Trehalos derivatives
DK375789D0 (en) PEPTIDE DERIVATIVES
DK19789A (en) DEHYDROCHOLCALCIFEROL DERIVATIVES
DK197989A (en) peptide
DE68927657D1 (en) Butynylamine derivatives
DK486089D0 (en) PYRANOBENZOXADIAZOLE DERIVATIVES
DK301889D0 (en) PEPTIDE DERIVATIVES
DK395288D0 (en) PROTEINS
DK177789A (en) PEPTIDE DERIVATIVES
FI91488B (en) Term
KR900700503A (en) Peptide
DK4390A (en) PEPTIDE DERIVATIVES
DE3824433A1 (en) FLUORCYCLOPROPYL DERIVATIVES
DK160389A (en) ARYLDION DERIVATIVES
DK657189A (en) PEPTIDE DERIVATIVES
ATA155589A (en) MITOMYCINPHOSPHATE DERIVATIVES
DK679488D0 (en) PEPTIDE DERIVATIVES
DK171489D0 (en) PEPTIDE DERIVATIVES

Legal Events

Date Code Title Description
PUP Patent expired