FI812980L - Nya kefalosporiner foerfarande foer framstaellning av dessa mellanprodukter daerav samt foerfarande foer framstaellning av mellanprodukter - Google Patents

Nya kefalosporiner foerfarande foer framstaellning av dessa mellanprodukter daerav samt foerfarande foer framstaellning av mellanprodukter

Info

Publication number
FI812980L
FI812980L FI812980A FI812980A FI812980L FI 812980 L FI812980 L FI 812980L FI 812980 A FI812980 A FI 812980A FI 812980 A FI812980 A FI 812980A FI 812980 L FI812980 L FI 812980L
Authority
FI
Finland
Prior art keywords
mellanprodukter
foerfarande foer
foer framstaellning
kefalosporiner
dessa
Prior art date
Application number
FI812980A
Other languages
English (en)
Other versions
FI75575B (fi
FI75575C (fi
Inventor
Hiroshi Sadaki
Hirokazu Narita
Hiroyuki Imaizumi
Yoshinori Konishi
Takihiro Inaba
Tatsuo Hirakawa
Hideo Taki
Masaru Tai
Yasuo Watanabe
Isamu Saikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55132253A external-priority patent/JPS5758689A/ja
Priority claimed from JP55158184A external-priority patent/JPS5782393A/ja
Priority claimed from JP55175263A external-priority patent/JPS6052755B2/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of FI812980L publication Critical patent/FI812980L/fi
Priority to FI870153A priority Critical patent/FI80041C/fi
Publication of FI75575B publication Critical patent/FI75575B/fi
Application granted granted Critical
Publication of FI75575C publication Critical patent/FI75575C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI812980A 1980-09-25 1981-09-24 Foerfarande foer framstaellning av nya cefalosporiner. FI75575C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI870153A FI80041C (fi) 1980-09-25 1987-01-15 Foerfarande foer framstaellning av 7-amino-3-(substituerad metyl)- 3 -cefem-4-karboxylsyror.

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP55132253A JPS5758689A (en) 1980-09-25 1980-09-25 Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids
JP13225380 1980-09-25
JP15818480 1980-11-12
JP55158184A JPS5782393A (en) 1980-11-12 1980-11-12 7-amino-3-(2-(1,2,3,4-tetrazolyl)methyl)cephem-4-carboxylic acid
JP17526380 1980-12-13
JP55175263A JPS6052755B2 (ja) 1980-12-13 1980-12-13 新規セファロスポリン類

Publications (3)

Publication Number Publication Date
FI812980L true FI812980L (fi) 1982-03-26
FI75575B FI75575B (fi) 1988-03-31
FI75575C FI75575C (fi) 1988-07-11

Family

ID=27316463

Family Applications (2)

Application Number Title Priority Date Filing Date
FI812980A FI75575C (fi) 1980-09-25 1981-09-24 Foerfarande foer framstaellning av nya cefalosporiner.
FI870153A FI80041C (fi) 1980-09-25 1987-01-15 Foerfarande foer framstaellning av 7-amino-3-(substituerad metyl)- 3 -cefem-4-karboxylsyror.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI870153A FI80041C (fi) 1980-09-25 1987-01-15 Foerfarande foer framstaellning av 7-amino-3-(substituerad metyl)- 3 -cefem-4-karboxylsyror.

Country Status (27)

Country Link
US (4) US4489072A (fi)
KR (1) KR860000932B1 (fi)
AR (1) AR240645A1 (fi)
AT (4) AT375082B (fi)
AU (3) AU550330B2 (fi)
CA (2) CA1204735A (fi)
CH (4) CH652130A5 (fi)
DD (2) DD208351A5 (fi)
DE (5) DE3152935C2 (fi)
DK (1) DK163877C (fi)
EG (1) EG17373A (fi)
ES (4) ES8301998A1 (fi)
FI (2) FI75575C (fi)
FR (2) FR2509310B1 (fi)
GB (3) GB2089339B (fi)
HU (1) HU185850B (fi)
IN (4) IN155375B (fi)
IT (1) IT1172201B (fi)
LU (1) LU83650A1 (fi)
MX (1) MX155025A (fi)
NL (1) NL8104386A (fi)
NO (1) NO161117C (fi)
NZ (1) NZ198350A (fi)
PH (5) PH18072A (fi)
PT (1) PT73727B (fi)
RO (4) RO82689A (fi)
SE (5) SE453090B (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
EP0061234A3 (en) * 1981-03-05 1983-11-16 Beecham Group Plc Cephalosporin derivatives, process for their preparation and pharmaceutical preparations containing them
EP0081971A3 (en) * 1981-12-08 1984-09-26 Tanabe Seiyaku Co., Ltd. Novel cephalosporin compound and process for preparing the same
DK521883A (da) * 1982-11-17 1984-05-18 Toyama Chemical Co Ltd Cephalosporinderivater, fremgangsmaade til fremstilling heraf og fremgangsmaade til fremstilling af mellemprodukter herfor
US4618606A (en) * 1982-11-17 1986-10-21 Toyama Chemical Co., Ltd. Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
GB8406231D0 (en) * 1984-03-09 1984-04-11 Fujisawa Pharmaceutical Co Cephem compounds
AT397086B (de) * 1984-05-25 1994-01-25 Toyama Chemical Co Ltd Verfahren zur herstellung von neuen 2-(2-aminothiazol-4-4yl)-2-(syn)-alkoxyimino- acetamiden
GB2161476B (en) * 1984-05-25 1988-01-27 Toyama Chemical Co Ltd 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
DE3539901A1 (de) * 1985-11-11 1987-05-14 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
JPH064643B2 (ja) * 1985-12-20 1994-01-19 ファイザー製薬株式会社 セフアロスポリン化合物
US4692517A (en) * 1986-03-20 1987-09-08 American Home Products Corporation C-3' acylaminooxy-7-[(2-aminothiazol-4-yl)-α-(substituted-oximino)acetyl]cephalosporin derivatives
EP0265185A3 (en) * 1986-10-21 1990-03-28 Beecham Group Plc Cephalosporins, processes for their preparation and pharmaceutical compositions containing them
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
EP0269298B1 (en) * 1986-11-21 1994-10-19 Ici Pharma Cephalosporins, process for their preparation and pharmaceutical compositions
DE3750673T2 (de) * 1986-11-21 1995-03-16 Ici Pharma Cephalosporine, Verfahren zu ihrer Herstellung und pharmazeutische Präparate.
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
GB8816519D0 (en) * 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
GB8811056D0 (en) * 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
JPH0699443B2 (ja) * 1989-09-29 1994-12-07 ファイザー製薬株式会社 セファロスポリン化合物
US6800756B2 (en) * 2002-05-03 2004-10-05 Orchid Chemicals And Pharmaceuticals, Ltd. Method for the preparation of ceftiofur sodium and its intermediates
US7847093B2 (en) * 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime
ES2348299T3 (es) * 2003-04-16 2010-12-02 Sandoz Ag Procedimientos para la preparación de cefepime.
JP2007530589A (ja) * 2004-03-26 2007-11-01 アンフォラ ディスカバリー コーポレーション 特定のトリアゾールを基礎とする化合物、組成物、およびそれらの使用
US8198434B2 (en) 2008-05-07 2012-06-12 Idexx Laboratories, Inc. Process for preparing cefsulodin sodium
EP2539348A4 (en) * 2010-02-26 2013-07-24 Gary Igor Dmitrienko CEPHALOSPORIN DERIVATIVES AS BETA LACTAMASE HEMMER AND COMPOSITIONS THEREFOR AND METHOD FOR THEIR USE
CN102351886B (zh) * 2011-09-07 2013-10-16 山东罗欣药业股份有限公司 头孢特仑新戊酯晶体、其制备方法及含有该晶体的组合物片剂
SG10201800325PA (en) 2013-07-17 2018-02-27 Otsuka Pharma Co Ltd Cyanotriazole compounds
CN106046026B (zh) * 2016-06-30 2018-07-06 济南康和医药科技有限公司 一种头孢特仑新戊酯的制备方法
CN112645842B (zh) * 2020-12-25 2022-08-19 复旦大学 一种氰乙酸叔丁酯的连续流制备方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912541A (en) * 1958-03-17 1962-12-12 Nat Res Dev Cephalosporin c compounds
DE1795484U (de) 1959-04-21 1959-09-10 Richard Langer Quertraeger fuer laengsdraehte zum abstuetzen von pflanzen, insbesondere weinreben.
GB1032641A (en) * 1962-02-16 1966-06-15 Edward Penley Abraham Cephalosporins
GB1057883A (en) * 1962-07-11 1967-02-08 Glaxo Lab Ltd Improvements in or relating to antibiotics
US3226384A (en) * 1963-01-25 1965-12-28 Nat Res Dev Cephalosporin ca derivatives
BE634644A (fi) * 1963-07-10
GB1211694A (en) * 1966-12-15 1970-11-11 Glaxo Lab Ltd Derivatives of 7-aminocephalosporanic acid
US3821206A (en) * 1966-12-15 1974-06-28 Glaxo Lab Ltd Cephalosporins having a polyazole substituent
DE2132883A1 (de) * 1970-07-08 1972-01-13 Ciba Geigy Ag Cephemverbindungen
US3932465A (en) * 1970-07-08 1976-01-13 Ciba-Geigy Corporation 3-R-methyl-7-amino-ceph-em-4-carboxylic acid compounds
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4343937A (en) * 1971-06-02 1982-08-10 Merck & Co., Inc. 3-Substituted-7-methoxy-7-amino-3-cephem-4-carboxylic acids
SU589918A3 (ru) * 1971-07-14 1978-01-25 Мерк Энд Ко Инк (Фирма) Способ получени сложного эфира 3-замещенной метил-7-ациломидо-7-метокси-2-цефем -4- карбоноаой кислоты
JPS5653557B2 (fi) * 1973-10-15 1981-12-19
CH605997A5 (fi) * 1974-08-30 1978-10-13 Ciba Geigy Ag
NO760358L (fi) * 1975-02-04 1976-08-05 Fujisawa Pharmaceutical Co
GB1547165A (en) * 1975-08-15 1979-06-06 Beecham Group Ltd 3-carbamoylbenzyl and 3-(carbamoylpyridylmethyl)-cephems
GB1575803A (en) * 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
US4165430A (en) * 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
JPS5946237B2 (ja) * 1976-04-02 1984-11-10 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
DE2710902A1 (de) * 1977-03-12 1978-09-21 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4148997A (en) * 1977-11-07 1979-04-10 Yeda Research And Development Co., Ltd. 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
DE2822861A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法
SE7908896L (sv) * 1978-10-27 1980-04-28 Glaxo Group Ltd Cefalosporinforeningar
IL58717A (en) * 1978-11-15 1983-05-15 Glaxo Group Ltd Derivatives of(6r,7r)-7-((z)-2-(2-aminothiazol-4-yl)-2-(carboxy-(lower alkyl or cycloalkyl)oxyimino)acetamido)-3-(2-alkyl-pyrazolium-1-ylmethyl)ceph-3-em-4-carboxylate,process for their preparation and pharmaceutical compositions comprising them
GB2043641B (en) * 1979-02-23 1983-07-20 Glaxo Group Ltd Cephalosporins
JPS55139387A (en) 1979-04-19 1980-10-31 Yamanouchi Pharmaceut Co Ltd Novel synthetic method of 7-amino-3-heterocyclic thiomethyl-delta3-carboxylic acids
JPS55153790A (en) 1979-05-17 1980-11-29 Yamanouchi Pharmaceut Co Ltd Preparation of 7-amino-3-heterocyclic thiomethyl-delta3- cephem-4-carboxylic acid
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
EP0061234A3 (en) * 1981-03-05 1983-11-16 Beecham Group Plc Cephalosporin derivatives, process for their preparation and pharmaceutical preparations containing them
DK163925C (da) * 1981-09-10 1992-09-14 Takeda Chemical Industries Ltd Fremgangsmaade til fremstilling af cephalosporinforbindelser
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
GB2161476B (en) * 1984-05-25 1988-01-27 Toyama Chemical Co Ltd 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof

Also Published As

Publication number Publication date
FI75575B (fi) 1988-03-31
IN158590B (fi) 1986-12-13
AT378961B (de) 1985-10-25
PT73727B (en) 1982-12-30
SE468476B (sv) 1993-01-25
US5144027A (en) 1992-09-01
ATA55583A (de) 1985-03-15
RO86823A (ro) 1985-05-20
PH20221A (en) 1986-10-23
AT375082B (de) 1984-06-25
DD208351A5 (de) 1984-05-02
FR2511377B1 (fr) 1985-12-13
GB8402250D0 (en) 1984-02-29
IN155375B (fi) 1985-01-19
DK421881A (da) 1982-04-15
CH652130A5 (de) 1985-10-31
NL8104386A (nl) 1982-04-16
IN158589B (fi) 1986-12-13
FI870153A0 (fi) 1987-01-15
GB8402249D0 (en) 1984-02-29
CA1204735A (en) 1986-05-20
FR2509310B1 (fr) 1985-08-02
AT378193B (de) 1985-06-25
SE8600192D0 (sv) 1986-01-16
SE8600193L (sv) 1986-01-16
GB2135304B (en) 1985-03-27
SE453090B (sv) 1988-01-11
SE8600195D0 (sv) 1986-01-16
FI870153A (fi) 1987-01-15
RO82689A (ro) 1983-11-01
CH652128A5 (de) 1985-10-31
PT73727A (en) 1981-10-01
DE3152932C2 (fi) 1990-02-08
IN159126B (fi) 1987-03-28
ES8306157A1 (es) 1983-05-01
RO82689B (ro) 1983-10-30
RO86825B (ro) 1985-05-31
ES505760A0 (es) 1983-01-01
MX155025A (es) 1988-01-20
SE468477B (sv) 1993-01-25
NO161117C (no) 1989-07-05
AU4986285A (en) 1986-04-24
CH652129A5 (de) 1985-10-31
SE8600192L (sv) 1986-01-16
ATA55683A (de) 1984-11-15
AT378962B (de) 1985-10-25
DE3152931C2 (fi) 1989-10-05
SE8600194L (sv) 1986-01-16
CA1200541A (en) 1986-02-11
CH651837A5 (de) 1985-10-15
ES514669A0 (es) 1983-05-01
LU83650A1 (fr) 1982-01-21
US4489072A (en) 1984-12-18
FI80041C (fi) 1990-04-10
RO86825A (ro) 1985-05-20
GB2089339B (en) 1985-04-24
NO813252L (no) 1982-03-26
ATA55483A (de) 1985-03-15
IT8149348A0 (it) 1981-09-23
ES514671A0 (es) 1983-05-01
SE8600193D0 (sv) 1986-01-16
US4879381A (en) 1989-11-07
ES8301998A1 (es) 1983-01-01
SE8105658L (sv) 1982-05-05
AU558649B2 (en) 1987-02-05
FR2511377A1 (fr) 1983-02-18
DE3137854A1 (de) 1982-04-15
RO86824A (ro) 1985-05-20
ATA410981A (de) 1983-11-15
FI80041B (fi) 1989-12-29
US4673738A (en) 1987-06-16
PH18072A (en) 1985-03-18
SE8600195L (sv) 1986-01-16
GB2089339A (en) 1982-06-23
AR240645A1 (es) 1990-07-31
HU185850B (en) 1985-04-28
DE3137854C2 (fi) 1987-06-19
ES8306155A1 (es) 1983-05-01
DE3152935C2 (fi) 1992-07-16
SE468479B (sv) 1993-01-25
SE8600194D0 (sv) 1986-01-16
FR2509310A1 (fr) 1983-01-14
NZ198350A (en) 1985-02-28
GB2136420A (en) 1984-09-19
PH18484A (en) 1985-08-02
EG17373A (en) 1990-12-30
SE468478B (sv) 1993-01-25
AU550330B2 (en) 1986-03-20
NO161117B (no) 1989-03-28
PH19147A (en) 1986-01-15
RO86823B (ro) 1985-05-31
DK163877B (da) 1992-04-13
ES514670A0 (es) 1983-05-01
ES8306156A1 (es) 1983-05-01
PH19251A (en) 1986-02-17
AU7543881A (en) 1982-04-01
RO86824B (ro) 1985-05-31
DD202436A5 (de) 1983-09-14
GB2135304A (en) 1984-08-30
KR860000932B1 (ko) 1986-07-19
DE3152934C2 (fi) 1990-01-18
DK163877C (da) 1992-09-14
IT1172201B (it) 1987-06-18
AU568033B2 (en) 1987-12-10
FI75575C (fi) 1988-07-11
AU4986185A (en) 1986-03-20
GB2136420B (en) 1985-05-01

Similar Documents

Publication Publication Date Title
FI812980L (fi) Nya kefalosporiner foerfarande foer framstaellning av dessa mellanprodukter daerav samt foerfarande foer framstaellning av mellanprodukter
FI814103L (fi) Foerfarande foer framstaellning av fiber- samt granulatmaterial anordning foer genomfoerande av foerfarandet foerfarande foer anvaendning av anordningen samt anvaendningen av fiber- samt granulatmaterialet
FI810287L (fi) Nya antihyperkolesterolemiska foereningar
FI812227L (fi) Rundslinga samt en av denna bildad stropp eller en av denna bildad rundslingematta
FI840667A0 (fi) Foerfarande foer framstaellning av en metallinsats samt metallinsats framstaelld enligt detta foerfarande
FI824540A0 (fi) Foerfarande foer framstaellning av en klubba samt en klubba framstaelld enligt naemnda foerfarande
FI810571L (fi) Tetrazolderivat foerfarande foer deras framstaellning samt dessa innehaollande saor-kompositioner
FI813794L (fi) Nya imidazolylfenylaminer deras framstaellningsfoerfarande ochderas farmaceutiskt anvaendning samt mellanprodukter av f rastaellning
FI811504L (fi) Nya triazolokinoxalin-4-oner
FI821833A0 (fi) Foerfarande foer framstaellning av nya antracykliner
FI811059L (fi) Foerfarande foer framstaellning av nya tricykliska etrar
FI821305A0 (fi) Foerfarande foer framstaellning av nya alifatiska fenylkarboxylsyraderivat
FI813946L (fi) Nya estrar
FI801843A (fi) Nya karbostyrilderivat
FI803435L (fi) Nya kopplingskomponenter foer oxidationshaorfaerger framstaellning daerav samt haorfaergmedel innehaollande dessa
FI810650L (fi) Elastomerkomposition samt daeck innehaollande densamma
FI821797A0 (fi) Foerfarande foer uppfoerande av en byggnad samt byggnadselement foer detta
FI812329L (fi) Foerfarande foer avlaegsnande av ytdefekter samt foer utfoerande av foerfarandet avsedd flerdelad braennare
FI811862L (fi) Foerfarande foer omformning av signalavsnitt foer kodad oeverfoering uppdelade talsignaler samt anordning foer genomfoerande av foerfarandet
FI830941L (fi) Nya 2- -d-ribofuranosylselenazol-4-karboxamidfoereningar samt foerfarande foer deras framstaellnin
FI65338B (fi) Foerfarande foer att skydda hanterbara foeremaol fraon foer krftig lutning samt varningsanordning foer tillaempning av efofarandet
FI822309L (fi) Borrskruv samt foerfarande foer framstaellning av densamma
FI830687A0 (fi) Saett foer automatisk dubbning samt dubbningsautomat foer genomfoerande av saettet
FI812085L (fi) Foerfarande foer avformning av huvudsakligen plattformiga betongelement samt lyftram foer utoevande av foerfarandet
FI813140L (fi) Nya prostaglandiner

Legal Events

Date Code Title Description
MA Patent expired

Owner name: TOYAMA CHEMICAL CO., LTD.