FI71134C - Foerfarande foer framstaellning av antifungicid 2-(2,4-difluorfenyl)-1,3-bis-(1h-1,2,4-triatsol-1-yl)-propan-2-ol - Google Patents

Foerfarande foer framstaellning av antifungicid 2-(2,4-difluorfenyl)-1,3-bis-(1h-1,2,4-triatsol-1-yl)-propan-2-ol Download PDF

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Publication number
FI71134C
FI71134C FI822005A FI822005A FI71134C FI 71134 C FI71134 C FI 71134C FI 822005 A FI822005 A FI 822005A FI 822005 A FI822005 A FI 822005A FI 71134 C FI71134 C FI 71134C
Authority
FI
Finland
Prior art keywords
compound
formula
triazole
bis
propan
Prior art date
Application number
FI822005A
Other languages
English (en)
Finnish (fi)
Other versions
FI71134B (fi
FI822005A0 (fi
FI822005L (fi
Inventor
Kenneth Richardson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27261198&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI71134(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of FI822005A0 publication Critical patent/FI822005A0/fi
Publication of FI822005L publication Critical patent/FI822005L/fi
Publication of FI71134B publication Critical patent/FI71134B/fi
Application granted granted Critical
Publication of FI71134C publication Critical patent/FI71134C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI822005A 1981-06-06 1982-06-04 Foerfarande foer framstaellning av antifungicid 2-(2,4-difluorfenyl)-1,3-bis-(1h-1,2,4-triatsol-1-yl)-propan-2-ol FI71134C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8117379 1981-06-06
GB8117379 1981-06-06
GB8131370 1981-10-17
GB8131370 1981-10-17
GB8206329 1982-03-04
GB8206329 1982-03-04

Publications (4)

Publication Number Publication Date
FI822005A0 FI822005A0 (fi) 1982-06-04
FI822005L FI822005L (fi) 1982-12-07
FI71134B FI71134B (fi) 1986-08-14
FI71134C true FI71134C (fi) 1986-11-24

Family

ID=27261198

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822005A FI71134C (fi) 1981-06-06 1982-06-04 Foerfarande foer framstaellning av antifungicid 2-(2,4-difluorfenyl)-1,3-bis-(1h-1,2,4-triatsol-1-yl)-propan-2-ol

Country Status (27)

Country Link
US (1) US4404216A (el)
EP (1) EP0069442B1 (el)
KR (1) KR850001132B1 (el)
AU (1) AU529987B2 (el)
CA (1) CA1181076A (el)
DE (1) DE3262386D1 (el)
DK (1) DK149849C (el)
EG (1) EG17222A (el)
ES (2) ES8307794A1 (el)
FI (1) FI71134C (el)
GR (1) GR76491B (el)
HK (1) HK8488A (el)
HU (1) HU189143B (el)
IE (1) IE53144B1 (el)
IL (1) IL65963A (el)
IN (1) IN158113B (el)
LU (1) LU88329I2 (el)
MX (1) MX7119E (el)
MY (1) MY8800094A (el)
NL (1) NL930061I2 (el)
NO (2) NO156128C (el)
NZ (1) NZ200864A (el)
PH (1) PH18015A (el)
PL (1) PL130909B1 (el)
PT (1) PT75017B (el)
SG (1) SG80887G (el)
YU (1) YU42770B (el)

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EP0548553A1 (en) * 1991-11-25 1993-06-30 Takeda Chemical Industries, Ltd. Optically active azole compounds, their production and use
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IL105200A (en) * 1993-03-29 1997-03-18 Teva Pharma Regiospecific processes for the preparation of 1, 3-bis (1, 2, 4-triazol-1-yl)-propan- 2-ol derivatives
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US6043064A (en) * 1993-10-22 2000-03-28 Bristol-Myers Squibb Company Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
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KR100194945B1 (ko) * 1997-01-29 1999-06-15 서치영 플루코나졸의 제조방법
GR980100028A (el) * 1998-01-15 1999-09-30 Drug Research Hellas ����� Φαρμακευτικα προιοντα για τοπικη χρηση που περιεχουν φλουκοναζολη σε συγκεντρωσεις μεταξυ 0,2% και 5%
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Also Published As

Publication number Publication date
FI71134B (fi) 1986-08-14
NO156128C (no) 1987-07-29
PT75017B (en) 1985-01-07
MY8800094A (en) 1988-12-31
NL930061I2 (nl) 1993-10-01
AU8448482A (en) 1982-12-23
EG17222A (en) 1991-03-30
ES512882A0 (es) 1983-08-01
DK252282A (da) 1982-12-07
PH18015A (en) 1985-02-28
KR850001132B1 (ko) 1985-08-09
NZ200864A (en) 1985-07-12
DK149849C (da) 1987-04-27
DE3262386D1 (en) 1985-03-28
LU88329I2 (fr) 1994-05-04
IE53144B1 (en) 1988-07-20
IL65963A (en) 1985-02-28
ES8307794A1 (es) 1983-08-01
US4404216A (en) 1983-09-13
FI822005A0 (fi) 1982-06-04
YU119582A (en) 1984-12-31
NO1994019I1 (no) 1994-11-02
PL236740A1 (en) 1983-04-25
GR76491B (el) 1984-08-10
HU189143B (en) 1986-06-30
IN158113B (el) 1986-09-06
AU529987B2 (en) 1983-06-30
NO821886L (no) 1982-12-07
SG80887G (en) 1988-09-16
CA1181076A (en) 1985-01-15
HK8488A (en) 1988-02-05
PT75017A (en) 1982-07-01
NO156128B (no) 1987-04-21
NL930061I1 (nl) 1993-09-01
IL65963A0 (en) 1982-09-30
ES520794A0 (es) 1984-05-01
EP0069442A1 (en) 1983-01-12
EP0069442B1 (en) 1985-02-20
ES8404348A1 (es) 1984-05-01
IE821285L (en) 1982-12-06
MX7119E (es) 1987-06-29
KR840000528A (ko) 1984-02-25
YU42770B (en) 1988-12-31
PL130909B1 (en) 1984-09-29
FI822005L (fi) 1982-12-07
DK149849B (da) 1986-10-13

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