DK252282A - Fremgangsmaade til fremstilling af 1,3-bis-(1,2,4-triazol-1-yl)-2-(2,4-difluorphenyl)propan-2-ol eller far aceutisk acceptable salte deraf - Google Patents

Fremgangsmaade til fremstilling af 1,3-bis-(1,2,4-triazol-1-yl)-2-(2,4-difluorphenyl)propan-2-ol eller far aceutisk acceptable salte deraf Download PDF

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Publication number
DK252282A
DK252282A DK252282A DK252282A DK252282A DK 252282 A DK252282 A DK 252282A DK 252282 A DK252282 A DK 252282A DK 252282 A DK252282 A DK 252282A DK 252282 A DK252282 A DK 252282A
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DK
Denmark
Prior art keywords
aceutic
difluorphenyl
triazol
propan
hazardous
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DK252282A
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English (en)
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DK149849C (da
DK149849B (da
Inventor
K Richardson
Original Assignee
Pfizer
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Application filed by Pfizer filed Critical Pfizer
Publication of DK252282A publication Critical patent/DK252282A/da
Publication of DK149849B publication Critical patent/DK149849B/da
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK252282A 1981-06-06 1982-06-04 Analogifremgangsmaade til fremstilling af 1,3-bis-(1,2,4-triazol-1-yl)-2-(2,4-difluorphenyl)-propan-2-ol eller farmaceutisk acceptable salte deraf DK149849C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8117379 1981-06-06
GB8117379 1981-06-06
GB8131370 1981-10-17
GB8131370 1981-10-17
GB8206329 1982-03-04
GB8206329 1982-03-04

Publications (3)

Publication Number Publication Date
DK252282A true DK252282A (da) 1982-12-07
DK149849B DK149849B (da) 1986-10-13
DK149849C DK149849C (da) 1987-04-27

Family

ID=27261198

Family Applications (1)

Application Number Title Priority Date Filing Date
DK252282A DK149849C (da) 1981-06-06 1982-06-04 Analogifremgangsmaade til fremstilling af 1,3-bis-(1,2,4-triazol-1-yl)-2-(2,4-difluorphenyl)-propan-2-ol eller farmaceutisk acceptable salte deraf

Country Status (27)

Country Link
US (1) US4404216A (da)
EP (1) EP0069442B1 (da)
KR (1) KR850001132B1 (da)
AU (1) AU529987B2 (da)
CA (1) CA1181076A (da)
DE (1) DE3262386D1 (da)
DK (1) DK149849C (da)
EG (1) EG17222A (da)
ES (2) ES8307794A1 (da)
FI (1) FI71134C (da)
GR (1) GR76491B (da)
HK (1) HK8488A (da)
HU (1) HU189143B (da)
IE (1) IE53144B1 (da)
IL (1) IL65963A (da)
IN (1) IN158113B (da)
LU (1) LU88329I2 (da)
MX (1) MX7119E (da)
MY (1) MY8800094A (da)
NL (1) NL930061I2 (da)
NO (2) NO156128C (da)
NZ (1) NZ200864A (da)
PH (1) PH18015A (da)
PL (1) PL130909B1 (da)
PT (1) PT75017B (da)
SG (1) SG80887G (da)
YU (1) YU42770B (da)

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Also Published As

Publication number Publication date
NL930061I2 (nl) 1993-10-01
NO156128C (no) 1987-07-29
KR850001132B1 (ko) 1985-08-09
DK149849C (da) 1987-04-27
GR76491B (da) 1984-08-10
ES512882A0 (es) 1983-08-01
IE821285L (en) 1982-12-06
NZ200864A (en) 1985-07-12
FI71134C (fi) 1986-11-24
ES520794A0 (es) 1984-05-01
IL65963A (en) 1985-02-28
PL236740A1 (en) 1983-04-25
IN158113B (da) 1986-09-06
MY8800094A (en) 1988-12-31
EP0069442B1 (en) 1985-02-20
FI822005A0 (fi) 1982-06-04
EG17222A (en) 1991-03-30
NO821886L (no) 1982-12-07
HK8488A (en) 1988-02-05
PH18015A (en) 1985-02-28
AU8448482A (en) 1982-12-23
EP0069442A1 (en) 1983-01-12
IL65963A0 (en) 1982-09-30
FI71134B (fi) 1986-08-14
CA1181076A (en) 1985-01-15
HU189143B (en) 1986-06-30
DK149849B (da) 1986-10-13
DE3262386D1 (en) 1985-03-28
NL930061I1 (nl) 1993-09-01
ES8307794A1 (es) 1983-08-01
SG80887G (en) 1988-09-16
LU88329I2 (fr) 1994-05-04
FI822005L (fi) 1982-12-07
PL130909B1 (en) 1984-09-29
IE53144B1 (en) 1988-07-20
NO156128B (no) 1987-04-21
PT75017A (en) 1982-07-01
MX7119E (es) 1987-06-29
US4404216A (en) 1983-09-13
YU119582A (en) 1984-12-31
NO1994019I1 (no) 1994-11-02
AU529987B2 (en) 1983-06-30
PT75017B (en) 1985-01-07
KR840000528A (ko) 1984-02-25
YU42770B (en) 1988-12-31
ES8404348A1 (es) 1984-05-01

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