FI63744C - Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat - Google Patents
Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat Download PDFInfo
- Publication number
- FI63744C FI63744C FI750256A FI750256A FI63744C FI 63744 C FI63744 C FI 63744C FI 750256 A FI750256 A FI 750256A FI 750256 A FI750256 A FI 750256A FI 63744 C FI63744 C FI 63744C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- cbz
- group
- give
- alk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT67286/74A IT1062206B (it) | 1974-02-01 | 1974-02-01 | Derivati della tirosina attivi sulla muscolatura liscia |
| IT6728674 | 1974-02-01 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI750256A FI750256A (no) | 1975-08-02 |
| FI63744B FI63744B (fi) | 1983-04-29 |
| FI63744C true FI63744C (fi) | 1983-08-10 |
Family
ID=11301149
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI750255A FI61479C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat |
| FI750256A FI63744C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI750255A FI61479C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4004008A (no) |
| JP (2) | JPS5417728B2 (no) |
| AT (2) | AT343632B (no) |
| BE (1) | BE824995A (no) |
| CA (2) | CA1047498A (no) |
| CH (2) | CH605658A5 (no) |
| DE (1) | DE2503992C2 (no) |
| ES (1) | ES434323A1 (no) |
| FI (2) | FI61479C (no) |
| FR (1) | FR2259592B1 (no) |
| GB (1) | GB1467927A (no) |
| HK (1) | HK38979A (no) |
| HU (2) | HU174825B (no) |
| IN (1) | IN139364B (no) |
| IT (1) | IT1062206B (no) |
| NL (1) | NL167683C (no) |
| NO (2) | NO144211C (no) |
| SE (2) | SE413094B (no) |
| ZA (1) | ZA75530B (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5225243A (en) * | 1975-08-20 | 1977-02-25 | Toshiba Electric Equip Corp | Distributing panel |
| US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
| US5198458A (en) * | 1986-02-04 | 1993-03-30 | Suntory Limited | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same |
| CA1320734C (en) * | 1986-02-04 | 1993-07-27 | Suntory Limited | Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same |
| NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
| IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical preparations containing them |
| US5258407A (en) * | 1991-12-31 | 1993-11-02 | Sterling Winthrop Inc. | 3,4-disubstituted phenols-immunomodulating agents |
| US5206373A (en) * | 1992-02-28 | 1993-04-27 | Merck & Co., Inc. | Process for preparing fibrinogen receptor antagonists |
| DE10204951A1 (de) * | 2002-02-06 | 2003-08-14 | Basf Ag | Phenylalaninderivate als Herbizide |
| EA200601105A1 (ru) * | 2003-12-19 | 2006-12-29 | Басф Акциенгезельшафт | Замещённые бензоилом фенилаланин-амиды |
| WO2007010885A1 (ja) | 2005-07-19 | 2007-01-25 | Daiichi Sankyo Company, Limited | 置換プロパンアミド誘導体及びそれを含む医薬組成物 |
| WO2011094890A1 (en) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators |
| WO2011156655A2 (en) * | 2010-06-09 | 2011-12-15 | Receptos, Inc. | Novel glp-1 receptor stabilizers and modulators |
| PT2713722T (pt) | 2011-05-31 | 2017-06-27 | Receptos Llc | Novos estabilizadores e moduladores do receptor glp-1 |
| AU2012352349B2 (en) | 2011-12-12 | 2017-08-17 | Receptos Llc | Carboxylic acid derivatives comprising four cycles acting as GLP-1 receptor modulators for therapy of diseases such as diabetes |
| CN102659619A (zh) * | 2012-04-18 | 2012-09-12 | 上海骏捷生化科技有限公司 | 一种合成酪氨酸衍生物的方法 |
| CN103508921B (zh) * | 2012-06-21 | 2015-09-30 | 贵州百灵企业集团制药股份有限公司 | 一种苯丙氨醇化合物的制备方法 |
| CN103508920B (zh) * | 2012-06-21 | 2016-03-02 | 贵州百灵企业集团制药股份有限公司 | 一种苯丙氨醇化合物的光学异构体的制备方法及其用途 |
| EP3008056B8 (en) | 2013-06-11 | 2021-03-03 | Receptos Llc | Novel glp-1 receptor modulators |
| CN112457301A (zh) | 2014-07-25 | 2021-03-09 | 赛尔基因第二国际有限公司 | 新的glp-1受体调节剂 |
| WO2016094729A1 (en) | 2014-12-10 | 2016-06-16 | Celgene International Ii Sarl | Glp-1 receptor modulators |
| CN107417560B (zh) * | 2017-03-30 | 2020-05-22 | 上海常丰生物医药科技有限公司 | 一种合成盐酸替罗酰胺的方法 |
| CN110015978B (zh) * | 2019-04-29 | 2021-03-19 | 康化（上海）新药研发有限公司 | O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法 |
| CN115850107A (zh) * | 2022-11-30 | 2023-03-28 | 苏州诚和医药化学有限公司 | 一种工业化合成盐酸替罗酰胺的方法 |
-
1974
- 1974-02-01 IT IT67286/74A patent/IT1062206B/it active Protection Beyond IP Right Term
-
1975
- 1975-01-22 GB GB287875A patent/GB1467927A/en not_active Expired
- 1975-01-24 ZA ZA00750530A patent/ZA75530B/xx unknown
- 1975-01-29 IN IN179/CAL/75A patent/IN139364B/en unknown
- 1975-01-30 CA CA219,027A patent/CA1047498A/en not_active Expired
- 1975-01-30 BE BE152889A patent/BE824995A/xx not_active IP Right Cessation
- 1975-01-30 CH CH110975A patent/CH605658A5/xx not_active IP Right Cessation
- 1975-01-30 FI FI750255A patent/FI61479C/fi not_active IP Right Cessation
- 1975-01-30 NO NO750288A patent/NO144211C/no unknown
- 1975-01-30 FI FI750256A patent/FI63744C/fi not_active IP Right Cessation
- 1975-01-30 CA CA75219028A patent/CA1048503A/en not_active Expired
- 1975-01-30 CH CH110875A patent/CH605657A5/xx not_active IP Right Cessation
- 1975-01-30 NO NO750287A patent/NO144210C/no unknown
- 1975-01-31 DE DE2503992A patent/DE2503992C2/de not_active Expired
- 1975-01-31 SE SE7501115A patent/SE413094B/xx unknown
- 1975-01-31 HU HU75RO820A patent/HU174825B/hu unknown
- 1975-01-31 AT AT74675A patent/AT343632B/de not_active IP Right Cessation
- 1975-01-31 HU HU75RO821A patent/HU175156B/hu unknown
- 1975-01-31 NL NL7501193A patent/NL167683C/xx not_active IP Right Cessation
- 1975-01-31 JP JP1326675A patent/JPS5417728B2/ja not_active Expired
- 1975-01-31 SE SE7501114A patent/SE410850B/xx not_active IP Right Cessation
- 1975-01-31 ES ES434323A patent/ES434323A1/es not_active Expired
- 1975-01-31 AT AT74575A patent/AT342026B/de not_active IP Right Cessation
- 1975-01-31 JP JP1328575A patent/JPS5417729B2/ja not_active Expired
- 1975-01-31 FR FR7503079A patent/FR2259592B1/fr not_active Expired
- 1975-02-03 US US05/546,481 patent/US4004008A/en not_active Expired - Lifetime
-
1979
- 1979-06-14 HK HK389/79A patent/HK38979A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: ROTTA RESEARCH LABORATORIUM S.P.A. |