FI63402C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl 2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl 2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat Download PDF

Info

Publication number
FI63402C
FI63402C FI781612A FI781612A FI63402C FI 63402 C FI63402 C FI 63402C FI 781612 A FI781612 A FI 781612A FI 781612 A FI781612 A FI 781612A FI 63402 C FI63402 C FI 63402C
Authority
FI
Finland
Prior art keywords
formula
trans
compound
hexahydro
choh
Prior art date
Application number
FI781612A
Other languages
English (en)
Finnish (fi)
Other versions
FI781612A (fi
FI63402B (fi
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI781612A publication Critical patent/FI781612A/fi
Priority to FI820468A priority Critical patent/FI68830C/fi
Application granted granted Critical
Publication of FI63402B publication Critical patent/FI63402B/fi
Publication of FI63402C publication Critical patent/FI63402C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI781612A 1977-05-23 1978-05-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl 2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat FI63402C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI820468A FI68830C (fi) 1977-05-23 1982-02-12 Dl- eller d-trans-8-fluor-5-(p-fluorfenyl)-2,3,4,4a,5,9b-heksahydro-1h-pyrido(4,3-b)indol som anvaends som mellanprodukt vid framstaellning av terapeutiskt anvaendbara 2-substituerade dl- och d-trans-8-fluor-5-(p-fluorfenyl)-2,3,4,4a,5,9b-heksahydro-1h-pyrido(4,3-b)indoler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23
US79939277 1977-05-23

Publications (3)

Publication Number Publication Date
FI781612A FI781612A (fi) 1978-11-24
FI63402B FI63402B (fi) 1983-02-28
FI63402C true FI63402C (fi) 1983-06-10

Family

ID=25175793

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781612A FI63402C (fi) 1977-05-23 1978-05-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl 2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat

Country Status (31)

Country Link
JP (1) JPS53144600A (ru)
AR (2) AR217688A1 (ru)
AT (1) AT368995B (ru)
AU (1) AU499618B1 (ru)
BE (1) BE867249A (ru)
CA (1) CA1094071A (ru)
CH (1) CH634321A5 (ru)
CS (1) CS207612B2 (ru)
DD (4) DD146186A5 (ru)
DE (1) DE2822465C2 (ru)
DK (1) DK226678A (ru)
EG (1) EG13590A (ru)
FI (1) FI63402C (ru)
FR (1) FR2392023A1 (ru)
GB (1) GB1586655A (ru)
GR (1) GR69985B (ru)
HU (3) HU187782B (ru)
IE (1) IE46975B1 (ru)
IL (1) IL54755A (ru)
IT (1) IT1096307B (ru)
LU (1) LU79684A1 (ru)
NL (1) NL7804210A (ru)
NO (2) NO150204C (ru)
NZ (1) NZ187333A (ru)
PH (1) PH13756A (ru)
PL (5) PL114541B1 (ru)
PT (1) PT68058B (ru)
SE (2) SE441448B (ru)
SU (4) SU873883A3 (ru)
YU (4) YU91478A (ru)
ZA (1) ZA782918B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (ru) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
IT1096307B (it) 1985-08-26
YU40796B (en) 1986-06-30
CA1094071A (en) 1981-01-20
AR217688A1 (es) 1980-04-15
DD138321A5 (de) 1979-10-24
IE46975B1 (en) 1983-11-16
GR69985B (ru) 1982-07-22
NO151862C (no) 1985-06-19
DD146186A5 (de) 1981-01-28
PL116944B1 (en) 1981-07-31
FR2392023B1 (ru) 1980-11-07
AT368995B (de) 1982-11-25
ATA369678A (de) 1982-04-15
IE781013L (en) 1978-11-23
SE441448B (sv) 1985-10-07
FI781612A (fi) 1978-11-24
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
HU187782B (en) 1986-02-28
HU185009B (en) 1984-11-28
NZ187333A (en) 1984-05-31
SE448459B (sv) 1987-02-23
SU818484A3 (ru) 1981-03-30
YU221882A (en) 1983-01-21
PL117107B1 (en) 1981-07-31
AR221721A1 (es) 1981-03-13
PT68058B (en) 1979-10-24
IL54755A (en) 1981-02-27
DD145537A5 (de) 1980-12-17
YU221682A (en) 1983-01-21
CH634321A5 (en) 1983-01-31
GB1586655A (en) 1981-03-25
DE2822465C2 (de) 1986-08-28
HU188802B (en) 1986-05-28
PT68058A (en) 1978-06-01
NO150204C (no) 1984-09-05
NO831790L (no) 1978-11-24
EG13590A (en) 1982-03-31
SU873883A3 (ru) 1981-10-15
YU91478A (en) 1983-01-21
JPS5711912B2 (ru) 1982-03-08
NL7804210A (nl) 1978-11-27
JPS53144600A (en) 1978-12-15
DD145536A5 (de) 1980-12-17
FR2392023A1 (fr) 1978-12-22
LU79684A1 (fr) 1979-12-06
SE8305917D0 (sv) 1983-10-27
CS207612B2 (en) 1981-08-31
FI63402B (fi) 1983-02-28
ZA782918B (en) 1979-06-27
IT7823673A0 (it) 1978-05-22
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
DK226678A (da) 1978-11-24
PL114547B1 (en) 1981-02-28
IL54755A0 (en) 1978-07-31
NO781770L (no) 1978-11-24
AU499618B1 (en) 1979-04-26
SU841589A3 (ru) 1981-06-23
DE2822465A1 (de) 1978-11-30
BE867249A (fr) 1978-11-20
NO151862B (no) 1985-03-11
PH13756A (en) 1980-09-17
SE8305917L (sv) 1983-10-27
YU221782A (en) 1983-01-21
NO150204B (no) 1984-05-28

Similar Documents

Publication Publication Date Title
EP0170213B1 (en) Glutarimide antianxiety and antihypertensive agents
US5652246A (en) Piperidine compounds
JPH06505715A (ja) 化合物
CS201040B2 (en) Method of producing etherified hydroxy-benzo-diheterocyclic compounds
FR2796644A1 (fr) Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JPH01190680A (ja) インドール誘導体およびその製造方法
FI63402C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d- och d1-trans-5-fenyl 2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)indolderivat
US4224329A (en) 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
FR2797874A1 (fr) Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA1264748A (en) .beta.-carboline-3-oxadiazolyl derivatives, method of preparing the same and_their use
NL193541C (nl) 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
FI71936B (fi) Foerfarande foer framstaellning av neuroleptiskt aktiva 2-substituerade-8-fluor-5-(4-fluorfenyl)-2,3,4,4a 5,9b-hexahydro-4a 9b-trans-1h-pyrido/4,3-b/indolderivat
HU224435B1 (hu) Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
US4612312A (en) Glutarimide antianxiety and antihypertensive agents
IL90533A (en) History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them
CA1273335A (en) Pyrrolo¬1,2-a| ¬4,1|benzoxazepine derivatives
US5071858A (en) Antipsychotic benzothiopyranylamines
US4616011A (en) Novel indole derivatives and pharmaceutical compositions containing same
CA1133483A (en) Hexahydro-trans-pyridoindole neuroleptic agents
EP0041630B1 (en) New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them
JP2744224B2 (ja) ビス−アザ−二環式抗不安薬の製法
US4267331A (en) Process for the production of 2-substituted pyrido[4,3-b]-indoles
US4252812A (en) 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
CZ211196A3 (en) Process for preparing pharmaceutically acceptable salts of naphthyridonecarboxylic acid
KR100382998B1 (ko) 6-메톡시-1h-벤조트리아졸-5-카르복사미드유도체,그제조방법및그것을함유하는의약조성물

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: PFIZER INC.