FI60707C - Foerfarande foer framstaellning av 2-(1,8-naftyridin-2-yl)-3-(1-piperazinyl)karbonyloxipyrroler anvaendbara saosom laekemedel - Google Patents
Foerfarande foer framstaellning av 2-(1,8-naftyridin-2-yl)-3-(1-piperazinyl)karbonyloxipyrroler anvaendbara saosom laekemedel Download PDFInfo
- Publication number
- FI60707C FI60707C FI753127A FI753127A FI60707C FI 60707 C FI60707 C FI 60707C FI 753127 A FI753127 A FI 753127A FI 753127 A FI753127 A FI 753127A FI 60707 C FI60707 C FI 60707C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- naphthyridin
- piperazinyl
- chloro
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7436963A FR2313060A1 (fr) | 1974-11-07 | 1974-11-07 | Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent |
FR7436963 | 1974-11-07 | ||
FR7527160A FR2322600A1 (fr) | 1975-09-04 | 1975-09-04 | Nouveaux derives de la pyrrolo (3,4-b) pyrazine, leur preparation et les compositions qui les contiennent |
FR7527161 | 1975-09-04 | ||
FR7527161A FR2322601A1 (fr) | 1975-09-04 | 1975-09-04 | Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent |
FR7527162A FR2322602A1 (fr) | 1975-09-04 | 1975-09-04 | Nouveaux derives de l'oxathiinno- et du dithiinnopyrrole, leur preparation et les compositions qui les contiennent |
FR7527160 | 1975-09-04 | ||
FR7527162 | 1975-09-04 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI753127A FI753127A (es) | 1976-05-08 |
FI60707B FI60707B (fi) | 1981-11-30 |
FI60707C true FI60707C (fi) | 1982-03-10 |
Family
ID=27446274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI753127A FI60707C (fi) | 1974-11-07 | 1975-11-07 | Foerfarande foer framstaellning av 2-(1,8-naftyridin-2-yl)-3-(1-piperazinyl)karbonyloxipyrroler anvaendbara saosom laekemedel |
Country Status (27)
Country | Link |
---|---|
US (1) | US4220646A (es) |
JP (2) | JPS5422996B2 (es) |
AR (2) | AR208414A1 (es) |
AT (2) | AT343123B (es) |
AU (1) | AU503200B2 (es) |
BE (1) | BE835325A (es) |
CA (1) | CA1057755A (es) |
CH (1) | CH609057A5 (es) |
CS (2) | CS231957B2 (es) |
CY (1) | CY1045A (es) |
DD (1) | DD122684A5 (es) |
DE (1) | DE2550111C2 (es) |
DK (1) | DK141098B (es) |
FI (1) | FI60707C (es) |
GB (1) | GB1468497A (es) |
HK (1) | HK19380A (es) |
HU (1) | HU173108B (es) |
IE (1) | IE41928B1 (es) |
IL (1) | IL48423A (es) |
LU (1) | LU73738A1 (es) |
NL (1) | NL177405C (es) |
NO (1) | NO143576C (es) |
OA (1) | OA05162A (es) |
PL (1) | PL101248B1 (es) |
SE (1) | SE407063B (es) |
SU (2) | SU673173A3 (es) |
YU (2) | YU39583B (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2371198A2 (fr) * | 1976-11-22 | 1978-06-16 | Rhone Poulenc Ind | Nouveaux derives du dithiepinno (1,4)(2,3-c) pyrrole, leur preparation et les compositions qui les contiennent |
US4533751A (en) * | 1981-10-09 | 1985-08-06 | Scm Corporation | Preparation of 1,3-dienamines from myrcene and substituted myrcene |
FR2525606A1 (fr) * | 1982-04-22 | 1983-10-28 | Rhone Poulenc Sante | Nouveaux derives du dithiino (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent |
FR2607506B1 (fr) * | 1986-12-02 | 1989-01-06 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2607504B1 (fr) * | 1986-12-02 | 1989-01-27 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2671800B1 (fr) * | 1991-01-17 | 1993-03-12 | Rhone Poulenc Rorer Sa | Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent. |
US5786357A (en) | 1991-12-02 | 1998-07-28 | Sepracor Inc. | Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone |
HU214331B (hu) * | 1992-06-17 | 1998-03-02 | Gyógyszerkutató Intézet Kft. | Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
US5565567A (en) * | 1993-06-04 | 1996-10-15 | Henkel Corporation. | Polymerizable N,N'-substituted piperazine acrylamide compounds |
US5922820A (en) * | 1993-06-04 | 1999-07-13 | Henkel Corporation | Polymerizable compounds |
AU6956394A (en) * | 1993-06-04 | 1995-01-03 | Henkel Corporation | Polymerizable compounds |
CZ87097A3 (en) | 1994-09-23 | 1997-11-12 | Arris Pharm Corp | Preparation for therapy and therapeutical methods for treating inflammations mediated by mast cells |
US5663357A (en) | 1995-11-22 | 1997-09-02 | Allergan | Substituted heteroarylamides having retinoid-like biological activity |
US5756742A (en) * | 1995-12-22 | 1998-05-26 | Henkel Corporation | Polymerizable compounds |
US6339086B1 (en) | 1999-05-14 | 2002-01-15 | Swpracor, Inc. | Methods of making and using N-desmethylzopiclone |
EP1396493A4 (en) * | 2001-04-26 | 2005-08-03 | Ajinomoto Kk | HETEROCYCLIC COMPOUNDS |
NZ535685A (en) * | 2002-03-29 | 2007-04-27 | Indevus Pharmaceuticals Inc | Preparation of 2-(7-chloro-1,8-napthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isindolinone, or pagoclone - a GABA receptor ligand |
WO2004037212A2 (en) * | 2002-10-24 | 2004-05-06 | Sepracor, Inc. | Compositions comprising zopiclone derivatives and methods of making and using the same |
US6909002B2 (en) * | 2002-11-22 | 2005-06-21 | Merck & Co., Inc. | Method of preparing inhibitors of phosphodiesterase-4 |
AR042194A1 (es) * | 2002-11-22 | 2005-06-15 | Merck & Co Inc | Metodo para preparar inhibidores de fosfodiesterasa - 4 |
CN1326856C (zh) * | 2002-11-22 | 2007-07-18 | 麦克公司 | 制备磷酸二酯酶-4抑制剂的方法 |
AU2004305563C1 (en) | 2003-12-11 | 2011-07-07 | Sunovion Pharmaceuticals Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
WO2005105061A2 (en) * | 2004-04-14 | 2005-11-10 | Indevus Pharmaceuticals, Inc. | Transdermal patch |
AU2006264317B2 (en) | 2005-07-06 | 2012-02-23 | Sunovion Pharmaceuticals Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
MX2008000249A (es) * | 2005-07-06 | 2008-03-18 | Sepracor Inc | Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos. |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
US20080305171A1 (en) * | 2007-06-07 | 2008-12-11 | Kristin Anne Arnold | Pyrrolopyrazine, formulations, methods of manufacture, and methods of use there |
CN100569775C (zh) * | 2007-12-19 | 2009-12-16 | 齐鲁天和惠世制药有限公司 | 佐匹克隆的晶型转换的方法 |
CA2750059C (en) | 2009-01-30 | 2014-11-18 | Sunovion Pharmaceuticals Inc. | Coated tablets of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine and methods for measuring effectiveness of coating |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
WO2018216406A1 (ja) * | 2017-05-25 | 2018-11-29 | 信越化学工業株式会社 | フルオロポリエーテル基含有ポリマー変性有機ケイ素化合物、表面処理剤及び物品 |
CN108129476A (zh) * | 2017-11-27 | 2018-06-08 | 华中农业大学 | 一种杂环内酰胺衍生物及其用于作物病原菌杀菌剂的用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1312427A (fr) * | 1961-04-12 | 1962-12-21 | Science Union Et Compagnie Soc | Nouveaux dérivés de la pipérazine et leurs préparations |
FR2101081B1 (es) * | 1970-08-19 | 1974-01-11 | Rhone Poulenc Sa | |
BE790408A (fr) * | 1971-10-22 | 1973-04-20 | Rhone Poulenc Sa | Nouveaux derives de la pyrrolo (3,4-b) pyridine, leur preparation et les compositions medicinales qui les |
OA04285A (fr) * | 1972-01-07 | 1979-12-31 | Rhone Poulenc Sa | Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation. |
BE793851A (fr) * | 1972-01-10 | 1973-07-10 | Rhone Poulenc Sa | Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent |
AR207555A1 (es) * | 1972-12-04 | 1976-10-15 | Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles | |
OA04700A (fr) * | 1973-05-15 | 1980-07-31 | Rhone Poulenc Sa | Nouveaux dérivés de la naphtyridine et leur procédé de préparation. |
-
1975
- 1975-01-01 AR AR261091A patent/AR208414A1/es active
- 1975-10-23 OA OA55663A patent/OA05162A/xx unknown
- 1975-10-30 NL NLAANVRAGE7512732,A patent/NL177405C/xx not_active IP Right Cessation
- 1975-11-03 CA CA238,909A patent/CA1057755A/fr not_active Expired
- 1975-11-05 JP JP75132198A patent/JPS5422996B2/ja not_active Expired
- 1975-11-05 DD DD189261A patent/DD122684A5/xx unknown
- 1975-11-05 IL IL48423A patent/IL48423A/xx unknown
- 1975-11-05 HU HU75RO868A patent/HU173108B/hu unknown
- 1975-11-05 IE IE2414/75A patent/IE41928B1/en unknown
- 1975-11-05 AU AU86331/75A patent/AU503200B2/en not_active Expired
- 1975-11-06 SE SE7512477A patent/SE407063B/xx not_active IP Right Cessation
- 1975-11-06 CH CH1437875A patent/CH609057A5/xx not_active IP Right Cessation
- 1975-11-06 BE BE161652A patent/BE835325A/xx not_active IP Right Cessation
- 1975-11-06 CY CY1045A patent/CY1045A/xx unknown
- 1975-11-06 GB GB4610375A patent/GB1468497A/en not_active Expired
- 1975-11-06 NO NO753713A patent/NO143576C/no unknown
- 1975-11-06 SU SU752186208A patent/SU673173A3/ru active
- 1975-11-06 DK DK499275AA patent/DK141098B/da not_active IP Right Cessation
- 1975-11-06 LU LU73738A patent/LU73738A1/xx unknown
- 1975-11-07 PL PL1975199797A patent/PL101248B1/pl unknown
- 1975-11-07 CS CS757510A patent/CS231957B2/cs unknown
- 1975-11-07 FI FI753127A patent/FI60707C/fi not_active IP Right Cessation
- 1975-11-07 DE DE2550111A patent/DE2550111C2/de not_active Expired
- 1975-11-07 YU YU2815/75A patent/YU39583B/xx unknown
- 1975-11-07 AT AT848675A patent/AT343123B/de not_active IP Right Cessation
-
1976
- 1976-07-02 AR AR263835A patent/AR208800A1/es active
- 1976-08-02 SU SU762385529A patent/SU604496A3/ru active
-
1977
- 1977-04-25 US US05/790,801 patent/US4220646A/en not_active Expired - Lifetime
- 1977-06-07 AT AT401977A patent/AT343666B/de not_active IP Right Cessation
- 1977-09-14 CS CS775983A patent/CS231958B2/cs unknown
-
1978
- 1978-10-13 JP JP12525778A patent/JPS5498790A/ja active Granted
-
1980
- 1980-04-10 HK HK193/80A patent/HK19380A/xx unknown
-
1982
- 1982-08-26 YU YU1921/82A patent/YU40087B/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: RHONE- POULENC INDUSTRIES |