FI113741B - Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi - Google Patents

Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi Download PDF

Info

Publication number
FI113741B
FI113741B FI992360A FI19992360A FI113741B FI 113741 B FI113741 B FI 113741B FI 992360 A FI992360 A FI 992360A FI 19992360 A FI19992360 A FI 19992360A FI 113741 B FI113741 B FI 113741B
Authority
FI
Finland
Prior art keywords
product
milk
fermentation
casein
peptides
Prior art date
Application number
FI992360A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI19992360A (fi
Inventor
Olli Tossavainen
Annika Maeyrae-Maekinen
Tarja Suomalainen
Janne Sahlsten
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FI992360A priority Critical patent/FI113741B/fi
Application filed by Valio Oy filed Critical Valio Oy
Priority to ES00972940T priority patent/ES2234686T3/es
Priority to EP00972940A priority patent/EP1226230B1/fr
Priority to AT00972941T priority patent/ATE266735T1/de
Priority to HU0203256A priority patent/HU226200B1/hu
Priority to HU0203185A priority patent/HUP0203185A3/hu
Priority to EEP200200230A priority patent/EE05461B1/xx
Priority to PL355670A priority patent/PL204119B1/pl
Priority to CNB008153353A priority patent/CN1164761C/zh
Priority to CZ20021431A priority patent/CZ302271B6/cs
Priority to AU11498/01A priority patent/AU777795B2/en
Priority to CNB008153930A priority patent/CN1197956C/zh
Priority to RU2002114359/13A priority patent/RU2276689C2/ru
Priority to JP2001535518A priority patent/JP3695648B2/ja
Priority to NZ518493A priority patent/NZ518493A/xx
Priority to PT00972941T priority patent/PT1226267E/pt
Priority to CA002388354A priority patent/CA2388354A1/fr
Priority to PCT/FI2000/000942 priority patent/WO2001032905A1/fr
Priority to US10/111,914 priority patent/US6890529B1/en
Priority to ES00972941T priority patent/ES2220557T3/es
Priority to EEP200200231A priority patent/EE200200231A/xx
Priority to DK00972941T priority patent/DK1226267T3/da
Priority to JP2001535586A priority patent/JP4172681B2/ja
Priority to PL00364790A priority patent/PL364790A1/xx
Priority to CZ20021369A priority patent/CZ294146B6/cs
Priority to DE60010742T priority patent/DE60010742T2/de
Priority to DE60016959T priority patent/DE60016959T2/de
Priority to DK00972940T priority patent/DK1226230T3/da
Priority to EP00972941A priority patent/EP1226267B1/fr
Priority to RU2002114327/13A priority patent/RU2270855C2/ru
Priority to KR1020027005618A priority patent/KR100718709B1/ko
Priority to AU11499/01A priority patent/AU769432B2/en
Priority to KR1020027005619A priority patent/KR100704441B1/ko
Priority to PCT/FI2000/000941 priority patent/WO2001032836A1/fr
Priority to NZ518470A priority patent/NZ518470A/xx
Priority to CA002387738A priority patent/CA2387738C/fr
Priority to PT00972940T priority patent/PT1226230E/pt
Priority to US10/111,942 priority patent/US6972282B1/en
Priority to AT00972940T priority patent/ATE285470T1/de
Publication of FI19992360A publication Critical patent/FI19992360A/fi
Priority to ZA200203172A priority patent/ZA200203172B/xx
Priority to ZA200203179A priority patent/ZA200203179B/xx
Priority to HR20020378A priority patent/HRP20020378B1/xx
Priority to HR20020377A priority patent/HRP20020377B1/xx
Priority to NO20022061A priority patent/NO330951B1/no
Priority to NO20022062A priority patent/NO20022062L/no
Application granted granted Critical
Publication of FI113741B publication Critical patent/FI113741B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/14Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1427Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by dialysis, reverse osmosis or hyperfiltration, e.g. for concentrating or desalting
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/30Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/147Helveticus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Water Supply & Treatment (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
FI992360A 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi FI113741B (fi)

Priority Applications (45)

Application Number Priority Date Filing Date Title
FI992360A FI113741B (fi) 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
CA002387738A CA2387738C (fr) 1999-11-01 2000-10-30 Procede de fabrication d'un produit contenant des tripeptides antihypertenseurs
AT00972941T ATE266735T1 (de) 1999-11-01 2000-10-30 Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält
HU0203256A HU226200B1 (en) 1999-11-01 2000-10-30 Process for producing a product containing antihypertensive tripeptides
HU0203185A HUP0203185A3 (en) 1999-11-01 2000-10-30 Lactobacillus helvetius producing antihypertensive di- and tripeptides
EEP200200230A EE05461B1 (et) 1999-11-01 2000-10-30 Antihpertensiivseid tripeptiide sisaldava toote valmistamise meetod
PL355670A PL204119B1 (pl) 1999-11-01 2000-10-30 Sposób wytwarzania produktu zawierającego trójpeptydy przeciw nadciśnieniu, produkt zawierający te trójpeptydy, produkt zawierający te trójpeptydy do zastosowania jako czynnik przeciw nadciścnieniu, produkt do zastosowania w wytwarzaniu substancji jadalnych, produkt do zastosowania w przemyśle i produkt jadalny
CNB008153353A CN1164761C (zh) 1999-11-01 2000-10-30 生产含抗高血压三肽产品的方法
CZ20021431A CZ302271B6 (cs) 1999-11-01 2000-10-30 Zpusob výroby produktu obsahujícího antihypertenzivní tripeptidy
AU11498/01A AU777795B2 (en) 1999-11-01 2000-10-30 Lactobacillus helveticus producing antihypertensive di- and tripeptides
CNB008153930A CN1197956C (zh) 1999-11-01 2000-10-30 产生抗高血压二和三肽的瑞士乳杆菌
RU2002114359/13A RU2276689C2 (ru) 1999-11-01 2000-10-30 Способ получения продукта, содержащего гипотензивные пептиды, продукт, полученный способом, и пищевой продукт
JP2001535518A JP3695648B2 (ja) 1999-11-01 2000-10-30 抗高血圧性ジペプチドおよびトリペプチドを産生するLactobacillus helveticus
NZ518493A NZ518493A (en) 1999-11-01 2000-10-30 Lactobacillus helvetius producing antihypertensive DI- and tripeptides
PT00972941T PT1226267E (pt) 1999-11-01 2000-10-30 Processo para produzir um produto tripeptidos anti-hipertensores
CA002388354A CA2388354A1 (fr) 1999-11-01 2000-10-30 Lactobacillus helveticus produisant des dipeptides et des tripeptides antihypertenseurs
PCT/FI2000/000942 WO2001032905A1 (fr) 1999-11-01 2000-10-30 Procede de fabrication d'un produit contenant des tripeptides antihypertenseurs
US10/111,914 US6890529B1 (en) 1999-11-01 2000-10-30 Lactobacillus helveticus producing antihypertensive di- and tripeptides
ES00972941T ES2220557T3 (es) 1999-11-01 2000-10-30 Procedimiento de fabricacion de un producto que contiene tripeptidos antihipertensores.
EEP200200231A EE200200231A (xx) 1999-11-01 2000-10-30 Antih�pertensiivseid di- ja tripeptiide produtseeriv Lactobacillus helveticus
DK00972941T DK1226267T3 (da) 1999-11-01 2000-10-30 Fremgangsmåde til fremstilling af et produkt, der indeholder antihypertensive tripeptider
JP2001535586A JP4172681B2 (ja) 1999-11-01 2000-10-30 抗高血圧性トリペプチドを含有する産物をつくる方法
ES00972940T ES2234686T3 (es) 1999-11-01 2000-10-30 Lactobacillus helveticus que produce dipeptidos y tripeptidos antihipertensivos.
PL00364790A PL364790A1 (en) 1999-11-01 2000-10-30 Lactobacillus helvetius producing antihypertensive di- and tripeptides
EP00972941A EP1226267B1 (fr) 1999-11-01 2000-10-30 Procede de fabrication d'un produit contenant des tripeptides antihypertenseurs
DE60016959T DE60016959T2 (de) 1999-11-01 2000-10-30 Lactobacillus helveticus, welches blutdrucksenkende di- und tripeptide herstellt
DK00972940T DK1226230T3 (da) 1999-11-01 2000-10-30 Lactobacillus helveticus, der producerer antihypertensive di- og tripeptider
DE60010742T DE60010742T2 (de) 1999-11-01 2000-10-30 Verfahren zur herstellung eines produktes, welches gegen bluthochdruck gerichtete tripeptide enthält
RU2002114327/13A RU2270855C2 (ru) 1999-11-01 2000-10-30 Штамм бактерий lactobacillus helveticus lbk-16 h, используемый для получения пробиотика, бактериальный пробиотический препарат и пищевой продукт
KR1020027005618A KR100718709B1 (ko) 1999-11-01 2000-10-30 항고혈압 트리펩타이드를 함유하는 제품의 생산 방법
AU11499/01A AU769432B2 (en) 1999-11-01 2000-10-30 Process for producing a product containing antihypertensive tripeptides
KR1020027005619A KR100704441B1 (ko) 1999-11-01 2000-10-30 항고혈압성 디펩타이드 및 트리펩타이드를 생산하는락토바실러스 헬베티쿠스
PCT/FI2000/000941 WO2001032836A1 (fr) 1999-11-01 2000-10-30 Lactobacillus helveticus produisant des dipeptides et des tripeptides antihypertenseurs
NZ518470A NZ518470A (en) 1999-11-01 2000-10-30 Process for producing a product containing antihypertensive peptides and the product formed by this process
EP00972940A EP1226230B1 (fr) 1999-11-01 2000-10-30 Lactobacillus helveticus produisant des dipeptides et des tripeptides antihypertenseurs
PT00972940T PT1226230E (pt) 1999-11-01 2000-10-30 Lactobacillus helvetius produtor de di e tripeptidos antihipertensores
US10/111,942 US6972282B1 (en) 1999-11-01 2000-10-30 Process for producing a product containing antihypertensive tripeptides
AT00972940T ATE285470T1 (de) 1999-11-01 2000-10-30 Lactobacillus helveticus, welches blutdrucksenkende di- und tripeptide herstellt
CZ20021369A CZ294146B6 (cs) 1999-11-01 2000-10-30 Lactobacillus helveticus LBK@�@ H a jeho použitíŹ bakteriální preparát a jedlý produkt
ZA200203172A ZA200203172B (en) 1999-11-01 2002-04-22 Lactobacillus helveticus producing antihypertensive di- and tripeptides.
ZA200203179A ZA200203179B (en) 1999-11-01 2002-04-22 Process for producing a product containing antihypertensive tripeptides.
HR20020378A HRP20020378B1 (en) 1999-11-01 2002-04-29 Lactobacillus helvetius producing antihypertensive di- and tripeptides
HR20020377A HRP20020377B1 (en) 1999-11-01 2002-04-29 Process for producing a product containing antihypertensive tripeptides
NO20022061A NO330951B1 (no) 1999-11-01 2002-04-30 Fremgangsmate for a fremstille produkter inneholdende antihypertensive tripeptider og produkter inneholdende disse
NO20022062A NO20022062L (no) 1999-11-01 2002-04-30 Lactobacillus helveticus som produserer antihypertensive di- og tripeptider

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI992360 1999-11-01
FI992360A FI113741B (fi) 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi

Publications (2)

Publication Number Publication Date
FI19992360A FI19992360A (fi) 2001-05-02
FI113741B true FI113741B (fi) 2004-06-15

Family

ID=8555541

Family Applications (1)

Application Number Title Priority Date Filing Date
FI992360A FI113741B (fi) 1999-11-01 1999-11-01 Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi

Country Status (23)

Country Link
US (2) US6972282B1 (fr)
EP (2) EP1226230B1 (fr)
JP (2) JP3695648B2 (fr)
KR (2) KR100718709B1 (fr)
CN (2) CN1164761C (fr)
AT (2) ATE266735T1 (fr)
AU (2) AU769432B2 (fr)
CA (2) CA2388354A1 (fr)
CZ (2) CZ302271B6 (fr)
DE (2) DE60010742T2 (fr)
DK (2) DK1226267T3 (fr)
EE (2) EE200200231A (fr)
ES (2) ES2220557T3 (fr)
FI (1) FI113741B (fr)
HR (2) HRP20020378B1 (fr)
HU (2) HU226200B1 (fr)
NO (2) NO20022062L (fr)
NZ (2) NZ518493A (fr)
PL (2) PL204119B1 (fr)
PT (2) PT1226230E (fr)
RU (2) RU2276689C2 (fr)
WO (2) WO2001032836A1 (fr)
ZA (2) ZA200203179B (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI113741B (fi) * 1999-11-01 2004-06-15 Valio Oy Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
FI112031B (fi) 2002-02-25 2003-10-31 Valio Oy Biologisesti aktiivisen tuotteen uusi käyttö
AU2003236689A1 (en) 2002-06-04 2003-12-19 Dsm Ip Assets B.V. Protein hydrolysate rich in tripeptides
CN100451127C (zh) * 2002-08-09 2009-01-14 科·汉森有限公司 制备具有抗高血压特性的肽的方法
PL378232A1 (pl) * 2003-01-06 2006-03-20 Unilever N.V. Fermentowany produkt mleczny, zawierający tripeptydy VPP i/albo IPP
TWI328457B (en) * 2003-03-18 2010-08-11 Suntory Holdings Ltd Angiotensin-converting enzyme inhibitory peptides
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
CA2523410A1 (fr) * 2003-05-05 2004-11-18 Unilever Plc Produit a base de caseine hydrolysee comportant des tripeptides ipp et/ou vpp
WO2005096847A1 (fr) * 2004-03-19 2005-10-20 Campina Nederland Holding B.V. Procede de preparation d'un ingredient alimentaire, produit alimentaire possedant des proprietes d'inhibition de l'enzyme de conversion de l'angiotensine i et produits ainsi obtenus
US20070224285A1 (en) * 2004-03-31 2007-09-27 Calpis Co., Ltd Agent for Preventing or Suppressing Hepatopathy and Functional Food for Preventing or Suppressing Hepatopathy
US7862808B2 (en) 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
JP4723501B2 (ja) * 2004-07-05 2011-07-13 カルピス株式会社 ペプチド混合物の製造法、抗高血圧ペプチド含有発酵乳の製造法及び抗高血圧ペプチド製剤の製造法
BRPI0513237A (pt) * 2004-07-12 2008-04-29 Dsm Assets B V hidrolisados de proteìna para diminuição de pressão sanguìnea
EP1685764A1 (fr) 2005-01-27 2006-08-02 Globus Egg Sciences B.V. Produits fonctionnels alimentaires hypotenseurs
NZ554278A (en) 2004-09-03 2009-11-27 Chr Hansen As Fermented milk or vegetable proteins comprising receoptor ligand and uses thereof
FR2876876B1 (fr) * 2004-10-22 2007-02-16 Gervais Danone Sa Protection d'ingredients alimentaires bioactifs par l'utilisation de microorganismes presentant une capacite de metabolisation reduite
FR2876874B1 (fr) * 2004-10-22 2007-02-16 Gervais Danone Sa Protection d'ingredients alimentaires bioactifs par l'utilisation d'ingredients leurres
US7879804B2 (en) * 2004-12-22 2011-02-01 Dsm Ip Assets B.V. Blood pressure lowering peptides in a single enzymatic step
WO2006084560A1 (fr) * 2005-02-09 2006-08-17 Unilever N.V. Composition comprenant un peptide
ES2599859T3 (es) * 2005-02-24 2017-02-03 Dsm Ip Assets B.V. Proceso enzimático para producir I-P-P a partir de caseína kappa
US7303745B2 (en) 2005-04-15 2007-12-04 Bristol-Myers Squibb Company Method for preventing or treating the development of respiratory allergies
EP2439266B1 (fr) 2005-11-28 2017-02-01 DSM IP Assets B.V. Préparations enzymatiques dans le but de diminuer un mauvais goût.
BRPI0707827A2 (pt) * 2006-02-14 2011-05-10 Calpis Co Ltd vasodilatador
DK1992352T3 (da) 2006-02-14 2014-06-10 Calpis Co Ltd Middel til anvendelse i forbyggelsen af aterosklerosis
ATE548445T1 (de) * 2006-02-20 2012-03-15 Gervais Danone Sa Laktose nicht fermentierende lactobacillus helveticus
EP1820849B1 (fr) * 2006-02-20 2009-01-21 Compagnie Gervais Danone Nouvelles souches de Lactobacillus helveticus
PT1820850E (pt) * 2006-02-20 2009-05-29 Gervais Danone Sa Novas estirpes de lactobacillus helveticus
CN100370019C (zh) * 2006-04-21 2008-02-20 江南大学 一种具有抗高血压作用的植物乳杆菌cw006
RU2457852C2 (ru) * 2006-05-15 2012-08-10 Валио Лтд Новое применение терапевтически эффективных пептидов
EP2040732A4 (fr) * 2006-05-15 2009-08-19 Valio Ltd Nouvelle utilisation de peptides thérapeutiquement utiles
CN101678051B (zh) * 2006-09-04 2012-12-12 雪印惠乳业株式会社 促进血中脂连蛋白浓度增加及/或抑制其减少的制剂及内脏脂肪蓄积抑制剂
PT1915913E (pt) 2006-10-23 2016-02-16 Nestec Sa Modulação do sabor e do aroma de produtos lácteos por biotransformação
ATE478568T1 (de) * 2007-02-02 2010-09-15 May Amadeus Alexander Produkt mit lebenden probiotischen mikroorganismen
US11759477B2 (en) 2007-02-26 2023-09-19 Heartbeet Ltd. Compositions of nitrates and methods of use thereof
US10842813B2 (en) 2007-02-26 2020-11-24 Heartbeet Ltd Compositions of nitrates and methods of use thereof
KR20090130303A (ko) * 2007-03-27 2009-12-22 칼피스가부시키가이샤 신부전 예방제
CA2725611A1 (fr) 2008-06-12 2009-12-17 Nestec S.A. Souches de lactobacillus helveticus produisant des peptides hypotenseurs
DE102008032828A1 (de) 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
FI122531B (fi) * 2009-09-30 2012-03-15 Valio Oy Juusto ja menetelmä sen valmistamiseksi
RU2453593C1 (ru) * 2011-04-21 2012-06-20 Общество с ограниченной ответственностью "Бифилюкс" Штамм lactobacillus helveticus, используемый для получения продукции, содержащей лактобактерии
CN102786580A (zh) * 2012-07-17 2012-11-21 上海交通大学 抗高血压活性肽ivp
CN102786579B (zh) * 2012-07-17 2014-07-09 上海交通大学 抗高血压活性肽vip
RU2580052C1 (ru) * 2014-12-24 2016-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм lactobacillus helveticus вкпм в-11176, полученный на доступных питательных средах
RU2577112C1 (ru) * 2014-12-25 2016-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм lactobacillus helveticus вкпм в-11175, полученный на доступных питательных средах
DK3788881T3 (da) 2016-12-02 2022-10-03 Fairlife Llc Ikke-brunfarvende laktosefrit mælkepulver og fremgangsmåder til fremstilling deraf
RU2685912C1 (ru) * 2018-03-14 2019-04-23 Федеральное государственное автономное научное учреждение "Научно-исследовательский институт хлебопекарной промышленности" Штамм бактерий lactobacillus amylolyticus, используемый для приготовления термофильной заквашенной заварки
RU2728171C2 (ru) * 2018-11-08 2020-07-28 Общество с ограниченной ответственностью "Инновационные биотехнологии" (ООО "Инбиотех") Штамм бактерий Lactobacillus helveticus T-5068, используемый в качестве закваски прямого внесения для приготовления кисломолочных продуктов
CN109517763B (zh) * 2018-12-27 2022-03-22 内蒙古农业大学 瑞士乳杆菌h11及其应用
TWI713972B (zh) * 2019-01-14 2020-12-21 大江生醫股份有限公司 改善呼吸道健康之益生菌株及其組合物與用途
WO2021195718A1 (fr) * 2020-04-02 2021-10-07 Ahtesh Fatah Bashir Procédé de fermentation lactique
CN112029784A (zh) * 2020-09-16 2020-12-04 内蒙古农业大学 一个与蛋白水解能力相关的基因及基于该基因的高蛋白水解能力瑞士乳杆菌的筛选方法
CN117986337A (zh) * 2024-02-02 2024-05-07 北京川晋生物科技有限公司 一种提高免疫力的益生菌组合物以及在治疗疾病中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2483748A1 (fr) * 1980-06-06 1981-12-11 Corning Glass Works Procede d'hydrolyse du lactose contenu dans les lactoserums a l'aide de lactase immobilisee
JPS6153216A (ja) * 1984-08-23 1986-03-17 Rikagaku Kenkyusho 高血圧症予防治療剤
JP2782142B2 (ja) * 1992-07-23 1998-07-30 カルピス株式会社 アンジオテンシン変換酵素阻害剤及びその製造法
JP2782153B2 (ja) 1992-11-09 1998-07-30 カルピス株式会社 アンジオテンシン変換酵素阻害ペプチドの製造法
JP2824821B2 (ja) 1993-11-04 1998-11-18 カルピス株式会社 乳酸菌及び発酵乳製品
GB2294191B (en) * 1994-10-06 1997-10-01 Waterford Creamery Ltd Cheese manufacture
JP3782837B2 (ja) * 1995-04-10 2006-06-07 カルピス株式会社 血圧降下剤及びその製造法
JPH09188694A (ja) 1996-01-10 1997-07-22 Otsuka Shokuhin Kk ペプチド、アンジオテンシン変換酵素阻害組成物及びその製法
JP3746556B2 (ja) 1996-02-09 2006-02-15 カルピス株式会社 プラスミド及びプラスミドベクター
US5854029A (en) * 1996-08-02 1998-12-29 Calpis Co., Ltd. Method for preparing antihypertensive agent
JP4727770B2 (ja) * 1997-09-26 2011-07-20 カルピス株式会社 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びFischer比低下の少なくとも1つの軽減剤
JP3028411B2 (ja) * 1997-09-26 2000-04-04 カルピス株式会社 トリペプチド高生産性ラクトバチルス・ヘルベチカス乳酸菌
FI104783B (fi) 1998-02-12 2000-04-14 Valio Oy Herasuolajauhe, menetelmä sen valmistamiseksi ja sen käyttö
FI113741B (fi) * 1999-11-01 2004-06-15 Valio Oy Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
US6514941B1 (en) * 1999-12-10 2003-02-04 Campina Melkunie B.V. Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides

Also Published As

Publication number Publication date
NO20022061L (no) 2002-06-28
KR100718709B1 (ko) 2007-05-16
AU1149901A (en) 2001-05-14
EP1226267A1 (fr) 2002-07-31
PL204119B1 (pl) 2009-12-31
NZ518493A (en) 2003-03-28
PT1226267E (pt) 2004-08-31
US6890529B1 (en) 2005-05-10
CN1387577A (zh) 2002-12-25
RU2276689C2 (ru) 2006-05-20
DE60010742T2 (de) 2005-05-12
EE05461B1 (et) 2011-08-15
ZA200203172B (en) 2003-09-23
CZ20021369A3 (cs) 2002-07-17
HU226200B1 (en) 2008-06-30
EE200200230A (et) 2003-06-16
HUP0203185A3 (en) 2005-07-28
ATE266735T1 (de) 2004-05-15
ZA200203179B (en) 2003-07-22
CZ294146B6 (cs) 2004-10-13
WO2001032905A1 (fr) 2001-05-10
CZ302271B6 (cs) 2011-01-19
AU777795B2 (en) 2004-10-28
DK1226267T3 (da) 2004-09-20
EP1226230A1 (fr) 2002-07-31
ES2220557T3 (es) 2004-12-16
PL355670A1 (en) 2004-05-04
NO330951B1 (no) 2011-08-22
KR100704441B1 (ko) 2007-04-24
KR20020064895A (ko) 2002-08-10
HUP0203256A2 (hu) 2003-01-28
PL364790A1 (en) 2004-12-13
CN1164761C (zh) 2004-09-01
HRP20020377B1 (en) 2005-06-30
PT1226230E (pt) 2005-04-29
CZ20021431A3 (cs) 2002-08-14
WO2001032836A1 (fr) 2001-05-10
CN1387564A (zh) 2002-12-25
EP1226267B1 (fr) 2004-05-12
NO20022061D0 (no) 2002-04-30
HUP0203256A3 (en) 2005-11-28
HRP20020378A2 (en) 2003-08-31
KR20020060220A (ko) 2002-07-16
RU2270855C2 (ru) 2006-02-27
NZ518470A (en) 2003-03-28
CN1197956C (zh) 2005-04-20
HUP0203185A2 (hu) 2003-01-28
DK1226230T3 (da) 2005-04-04
DE60016959T2 (de) 2005-12-22
EP1226230B1 (fr) 2004-12-22
JP4172681B2 (ja) 2008-10-29
NO20022062D0 (no) 2002-04-30
NO20022062L (no) 2002-06-28
DE60010742D1 (de) 2004-06-17
DE60016959D1 (de) 2005-01-27
CA2387738C (fr) 2008-09-16
JP3695648B2 (ja) 2005-09-14
EE200200231A (xx) 2003-06-16
CA2388354A1 (fr) 2001-05-10
JP2003513621A (ja) 2003-04-15
FI19992360A (fi) 2001-05-02
ATE285470T1 (de) 2005-01-15
CA2387738A1 (fr) 2001-05-10
HRP20020378B1 (en) 2005-06-30
JP2003513636A (ja) 2003-04-15
AU1149801A (en) 2001-05-14
AU769432B2 (en) 2004-01-29
ES2234686T3 (es) 2005-07-01
HRP20020377A2 (en) 2003-08-31
US6972282B1 (en) 2005-12-06

Similar Documents

Publication Publication Date Title
FI113741B (fi) Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
Takano Anti-hypertensive activity of fermented dairy products containing biogenic peptides
JP5888701B2 (ja) 高タンパク質分解活性を有するラクトバチルス・ヘルベティカス菌
JP2011504363A (ja) 改良された生理活性ペプチドの生成
MXPA05007267A (es) Producto de leche fermentada que comprende tripeptidos val-pro-pro (vpp) e ile-pro-pro (ipp).
WO2013046031A2 (fr) Souches de lactococcus lactis et ses préparations bactériennes, pour la production de peptides bioactifs ayant des effets antihypertenseurs et d'abaissement du cholestérol chez les mammifères ; produits nutritionnels et thérapeutiques dérivés
FI112031B (fi) Biologisesti aktiivisen tuotteen uusi käyttö
FI120267B (fi) Menetelmä terapeuttisesti käyttökelpoisten peptidien valmistamiseksi
JP4268785B2 (ja) カルシウム吸収促進及びリン酸カルシウム結晶成長促進剤
Acharya Production of functional food, Fruit ravioli with antihypertensive peptides
EP1820405A1 (fr) Nouvelles souches de Lactobacillus Helveticus

Legal Events

Date Code Title Description
MM Patent lapsed