BRPI0513237A - hidrolisados de proteìna para diminuição de pressão sanguìnea - Google Patents

hidrolisados de proteìna para diminuição de pressão sanguìnea

Info

Publication number
BRPI0513237A
BRPI0513237A BRPI0513237-1A BRPI0513237A BRPI0513237A BR PI0513237 A BRPI0513237 A BR PI0513237A BR PI0513237 A BRPI0513237 A BR PI0513237A BR PI0513237 A BRPI0513237 A BR PI0513237A
Authority
BR
Brazil
Prior art keywords
blood pressure
protein hydrolysates
lowering blood
protein
ipp
Prior art date
Application number
BRPI0513237-1A
Other languages
English (en)
Inventor
Luppo Edens
Andre Leonardus De Roos
Robertus Antonius Mijnd Hoeven
Philippus Antonius Deen
Original Assignee
Dsm Assets B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Assets B V filed Critical Dsm Assets B V
Publication of BRPI0513237A publication Critical patent/BRPI0513237A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

HIDROLISADOS DE PROTEìNA PARA DIMINUIçãO DE PRESSãO SANGUìNEA A presente invenção descreve um processo para produzir IPP a partir de uma fonte de proteína, pelo que a proporção de IPP e VPP produzidos pela proteína é de pelo menos 5, de preferência pelo menos 10 e mais preferivelmente pelo menos 20, o qual compreende o uso de uma endoprotease prolina específica.
BRPI0513237-1A 2004-07-12 2005-07-12 hidrolisados de proteìna para diminuição de pressão sanguìnea BRPI0513237A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP04077015 2004-07-12
EP04103593 2004-07-27
EP04106859 2004-12-22
PCT/EP2005/053336 WO2006005757A2 (en) 2004-07-12 2005-07-12 Blood pressure lowering oligopeptides

Publications (1)

Publication Number Publication Date
BRPI0513237A true BRPI0513237A (pt) 2008-04-29

Family

ID=35784222

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513237-1A BRPI0513237A (pt) 2004-07-12 2005-07-12 hidrolisados de proteìna para diminuição de pressão sanguìnea

Country Status (9)

Country Link
US (1) US20070207944A1 (pt)
EP (1) EP1774014A2 (pt)
JP (1) JP2008505653A (pt)
AU (1) AU2005261652A1 (pt)
BR (1) BRPI0513237A (pt)
CA (1) CA2569926A1 (pt)
EA (1) EA011865B1 (pt)
NZ (1) NZ552140A (pt)
WO (1) WO2006005757A2 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004098309A1 (en) 2003-05-05 2004-11-18 Unilever N.V. Hydrolysed casein product comprising tripeptides ipp and/ or vpp
DK1663298T3 (da) * 2003-09-23 2019-10-14 Dsm Ip Assets Bv Anvendelse af prolinspecifikke endoproteaser til hydrolyse af peptider og proteiner
JP5106117B2 (ja) * 2004-12-22 2012-12-26 ディーエスエム アイピー アセッツ ビー．ブイ． 単一の酵素工程における血圧降下ペプチド
ATE542896T1 (de) 2004-12-23 2012-02-15 Campina Nederland Holding Bv Mit dpp-iv hemmenden peptiden angereichertes proteinhydrolysat und deren verwendung
JP4732112B2 (ja) * 2005-01-20 2011-07-27 サッポロビール株式会社 発泡アルコール飲料の製造方法及びその方法を用いて製造された発泡アルコール飲料
ES2599859T3 (es) * 2005-02-24 2017-02-03 Dsm Ip Assets B.V. Proceso enzimático para producir I-P-P a partir de caseína kappa
ZA200709009B (en) * 2005-04-28 2009-01-28 Unilever Plc Peptides having an ace inhibiting effect
TW200803751A (en) 2005-11-30 2008-01-16 Campina Nederland Holding Bv Use of a protein hydrolysate for enhancing activity of glucagon-like peptide-1
RU2446210C2 (ru) * 2006-02-02 2012-03-27 ДСМ АйПи АССЕТС Б.В. Пищевой продукт, содержащий специфичную к пролину протеазу, способ его производства и его применение для расщепления токсичных или аллергенных пептидов глютена
KR101048663B1 (ko) * 2006-02-14 2011-07-12 칼피스가부시키가이샤 동맥경화 예방제, 혈관 내막의 비후 억제제 및 혈관 내피 기능 개선제
CA2652388A1 (en) 2006-05-15 2007-11-22 Valio Ltd New use of therapeutically useful peptides
MX2009010427A (es) * 2007-03-27 2009-10-20 Calpis Co Ltd Agente profilactico para la insuficiencia cardiaca.
TWI414305B (zh) * 2007-03-27 2013-11-11 Calpis Co Ltd 腎衰竭預防劑
JP5736533B2 (ja) * 2007-07-19 2015-06-17 学校法人北里研究所 抗ストレス作用と嗜好性向上効果を備えたペプチド性ペットフード素材
WO2009065862A1 (en) * 2007-11-23 2009-05-28 Dsm Ip Assets B.V. Improved bioactive peptide production
WO2010046298A2 (en) * 2008-10-21 2010-04-29 Dsm Ip Assets B.V. Improved peptide availability
JP2011136932A (ja) * 2009-12-28 2011-07-14 Calpis Co Ltd 脳機能改善用組成物および脳機能を改善する方法
NO20100370A1 (no) 2010-03-08 2011-09-09 Marine Bioproducts As Peptidmateriale, fôrsammensetninger og preparater, og anvendelser derav.
NO20100359A1 (no) 2010-03-08 2011-09-09 Marine Bioproducts As Peptidmateriale og preparater og anvendelser derav.
NO20100369A1 (no) 2010-03-08 2011-09-09 Marine Bioproducts As Peptidmateriale, fôrsammensetning og preparater og anvendelser derav.
JP5718741B2 (ja) * 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
CN103204909B (zh) * 2013-04-17 2014-09-03 苏州凯祥生物科技有限公司 一种抗高血压活性肽vppipp
US9530146B2 (en) * 2013-09-05 2016-12-27 Dsm Ip Assets B.V. Marketing the use of an acidic soft drink to enhance the efficacy of a gluten-digesting enzyme
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
US11918007B2 (en) * 2017-12-14 2024-03-05 Universidade Do Porto Foodstuff composition comprising a derivate of olive pomace

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486461A (en) * 1991-11-08 1996-01-23 Novo Nordisk A/S Casein hydrolyzate and method for production of such casein hydrolyzate
JP4727770B2 (ja) * 1997-09-26 2011-07-20 カルピス株式会社 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤
FI113741B (fi) * 1999-11-01 2004-06-15 Valio Oy Menetelmä verenpainetta alentavia peptidejä sisältävän tuotteen valmistamiseksi
JP4633876B2 (ja) * 1999-11-11 2011-02-16 カルピス株式会社 トリペプチドの製造方法
AU2001255501A1 (en) * 2000-04-21 2001-11-07 Monsanto Technology Llc Blood-pressure reducing polypeptides containing vpp derived from microorganisms
DE60222420T2 (de) * 2001-07-18 2008-06-12 Dsm Ip Assets B.V. Verfahren zur hydrolyse von milcheiweissen
WO2004098309A1 (en) * 2003-05-05 2004-11-18 Unilever N.V. Hydrolysed casein product comprising tripeptides ipp and/ or vpp

Also Published As

Publication number Publication date
WO2006005757A3 (en) 2007-03-15
EA200700215A1 (ru) 2007-06-29
AU2005261652A1 (en) 2006-01-19
CA2569926A1 (en) 2006-01-19
JP2008505653A (ja) 2008-02-28
WO2006005757A2 (en) 2006-01-19
NZ552140A (en) 2009-02-28
EA011865B1 (ru) 2009-06-30
EP1774014A2 (en) 2007-04-18
US20070207944A1 (en) 2007-09-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.