FI105695B - Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi - Google Patents

Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi Download PDF

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Publication number
FI105695B
FI105695B FI885719A FI885719A FI105695B FI 105695 B FI105695 B FI 105695B FI 885719 A FI885719 A FI 885719A FI 885719 A FI885719 A FI 885719A FI 105695 B FI105695 B FI 105695B
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FI
Finland
Prior art keywords
subtilisin
asn
ser
analog
asp
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FI885719A
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English (en)
Finnish (fi)
Swedish (sv)
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FI885719A0 (fi
FI885719A (fi
Inventor
Yitzhak Stabinsky
Mark M Zukowski
Michael Levitt
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Amgen Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI885719A 1987-04-10 1988-12-09 Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi FI105695B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3687287 1987-04-10
US07/036,872 US4914031A (en) 1987-04-10 1987-04-10 Subtilisin analogs
PCT/US1988/001038 WO1988008033A1 (en) 1987-04-10 1988-03-28 Subtilisin analogs
US8801038 1988-03-28

Publications (3)

Publication Number Publication Date
FI885719A0 FI885719A0 (fi) 1988-12-09
FI885719A FI885719A (fi) 1988-12-09
FI105695B true FI105695B (fi) 2000-09-29

Family

ID=21891131

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885719A FI105695B (fi) 1987-04-10 1988-12-09 Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi

Country Status (15)

Country Link
US (1) US4914031A (xx)
EP (1) EP0309565B2 (xx)
JP (1) JP2590247B2 (xx)
KR (1) KR960006120B1 (xx)
AT (1) ATE119941T1 (xx)
AU (1) AU612653B2 (xx)
CA (1) CA1316473C (xx)
DE (1) DE3853328T3 (xx)
DK (1) DK175576B1 (xx)
FI (1) FI105695B (xx)
HK (1) HK1007168A1 (xx)
IL (1) IL85953A (xx)
LV (1) LV11043B (xx)
NO (1) NO179679C (xx)
WO (1) WO1988008033A1 (xx)

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EP3703661A1 (en) 2017-11-02 2020-09-09 Danisco US Inc. Freezing point depressed solid matrix compositions for melt granulation of enzymes
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CN116322625A (zh) 2020-08-24 2023-06-23 诺维信公司 包含果聚糖酶的口腔护理组合物
CN117881772A (zh) 2021-08-20 2024-04-12 丹尼斯科美国公司 编码新型核酸酶的多核苷酸、其组合物及其从蛋白质制剂中消除dna的方法

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Publication number Publication date
KR960006120B1 (ko) 1996-05-09
NO179679B (no) 1996-08-19
NO179679C (no) 1996-11-27
DK175576B1 (da) 2004-12-13
EP0309565B1 (en) 1995-03-15
LV11043B (en) 1996-06-20
NO885484L (no) 1989-02-09
JP2590247B2 (ja) 1997-03-12
EP0309565A4 (xx) 1990-02-05
HK1007168A1 (en) 1999-04-01
FI885719A0 (fi) 1988-12-09
EP0309565A1 (en) 1989-04-05
ATE119941T1 (de) 1995-04-15
US4914031A (en) 1990-04-03
EP0309565B2 (en) 2001-08-22
NO885484D0 (no) 1988-12-09
CA1316473C (en) 1993-04-20
DE3853328T2 (de) 1995-07-27
DE3853328T3 (de) 2002-06-06
IL85953A (en) 1993-01-31
DE3853328D1 (de) 1995-04-20
AU1701688A (en) 1988-11-04
AU612653B2 (en) 1991-07-18
JPH01502957A (ja) 1989-10-12
IL85953A0 (en) 1988-09-30
FI885719A (fi) 1988-12-09
WO1988008033A1 (en) 1988-10-20
DK686788A (da) 1988-12-09
DK686788D0 (da) 1988-12-09
KR890700668A (ko) 1989-04-26
LV11043A (lv) 1996-02-20

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