FI885719A0 - Analoger av subtilisin. - Google Patents

Analoger av subtilisin.

Info

Publication number
FI885719A0
FI885719A0 FI885719A FI885719A FI885719A0 FI 885719 A0 FI885719 A0 FI 885719A0 FI 885719 A FI885719 A FI 885719A FI 885719 A FI885719 A FI 885719A FI 885719 A0 FI885719 A0 FI 885719A0
Authority
FI
Finland
Prior art keywords
subtilisin
asn
calcium binding
gly
analogs
Prior art date
Application number
FI885719A
Other languages
English (en)
Other versions
FI105695B (fi
FI885719A (fi
Inventor
Mark M Zukowski
Yitzhak Stabinsky
Michael Levitt
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21891131&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI885719(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI885719A0 publication Critical patent/FI885719A0/fi
Publication of FI885719A publication Critical patent/FI885719A/fi
Application granted granted Critical
Publication of FI105695B publication Critical patent/FI105695B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FI885719A 1987-04-10 1988-12-09 Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi FI105695B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/036,872 US4914031A (en) 1987-04-10 1987-04-10 Subtilisin analogs
US3687287 1987-04-10
PCT/US1988/001038 WO1988008033A1 (en) 1987-04-10 1988-03-28 Subtilisin analogs
US8801038 1988-03-28

Publications (3)

Publication Number Publication Date
FI885719A0 true FI885719A0 (fi) 1988-12-09
FI885719A FI885719A (fi) 1988-12-09
FI105695B FI105695B (fi) 2000-09-29

Family

ID=21891131

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885719A FI105695B (fi) 1987-04-10 1988-12-09 Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi

Country Status (15)

Country Link
US (1) US4914031A (fi)
EP (1) EP0309565B2 (fi)
JP (1) JP2590247B2 (fi)
KR (1) KR960006120B1 (fi)
AT (1) ATE119941T1 (fi)
AU (1) AU612653B2 (fi)
CA (1) CA1316473C (fi)
DE (1) DE3853328T3 (fi)
DK (1) DK175576B1 (fi)
FI (1) FI105695B (fi)
HK (1) HK1007168A1 (fi)
IL (1) IL85953A (fi)
LV (1) LV11043B (fi)
NO (1) NO179679C (fi)
WO (1) WO1988008033A1 (fi)

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JP2015500006A (ja) * 2011-11-25 2015-01-05 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体およびこれをコードするポリヌクレオチド
JP6585602B2 (ja) 2013-12-31 2019-10-02 ダニスコ・ユーエス・インク タンパク質発現の増大
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US11866713B2 (en) 2017-02-24 2024-01-09 Danisco Us Inc. Compositions and methods for increased protein production in bacillus licheniformis
EP3655537A1 (en) 2017-08-23 2020-05-27 Danisco US Inc. Methods and compositions for efficient genetic modifications of bacillus licheniformis strains
EP3682010A1 (en) 2017-09-13 2020-07-22 Danisco US Inc. Modified 5'-untranslated region (utr) sequences for increased protein production in bacillus
WO2019089898A1 (en) 2017-11-02 2019-05-09 Danisco Us Inc Freezing point depressed solid matrix compositions for melt granulation of enzymes
DK3735478T3 (da) 2018-01-03 2023-10-30 Danisco Us Inc Mutante og genmodificerede bacillus-celler og fremgangsmåder dertil til forøget proteinproduktion
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JP2023524334A (ja) 2020-01-15 2023-06-12 ダニスコ・ユーエス・インク バチルス・リケニフォルミス（ｂａｃｉｌｌｕｓ ｌｉｃｈｅｎｉｆｏｒｍｉｓ）における強化したタンパク質産生のための組成物及び方法
KR20230057391A (ko) 2020-08-24 2023-04-28 노보자임스 에이/에스 프럭타나제를 포함하는 구강 관리 조성물
CN117881772A (zh) 2021-08-20 2024-04-12 丹尼斯科美国公司 编码新型核酸酶的多核苷酸、其组合物及其从蛋白质制剂中消除dna的方法

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ATE184316T1 (de) * 1987-04-06 1999-09-15 Novo Nordisk As Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen

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IL85953A0 (en) 1988-09-30
KR960006120B1 (ko) 1996-05-09
LV11043A (lv) 1996-02-20
NO179679B (no) 1996-08-19
EP0309565B2 (en) 2001-08-22
DE3853328D1 (de) 1995-04-20
FI105695B (fi) 2000-09-29
WO1988008033A1 (en) 1988-10-20
US4914031A (en) 1990-04-03
JP2590247B2 (ja) 1997-03-12
AU612653B2 (en) 1991-07-18
ATE119941T1 (de) 1995-04-15
EP0309565A4 (fi) 1990-02-05
DK686788D0 (da) 1988-12-09
DK686788A (da) 1988-12-09
NO179679C (no) 1996-11-27
DK175576B1 (da) 2004-12-13
NO885484D0 (no) 1988-12-09
JPH01502957A (ja) 1989-10-12
AU1701688A (en) 1988-11-04
DE3853328T3 (de) 2002-06-06
EP0309565A1 (en) 1989-04-05
FI885719A (fi) 1988-12-09
KR890700668A (ko) 1989-04-26
DE3853328T2 (de) 1995-07-27
NO885484L (no) 1989-02-09
CA1316473C (en) 1993-04-20
LV11043B (en) 1996-06-20
EP0309565B1 (en) 1995-03-15
HK1007168A1 (en) 1999-04-01
IL85953A (en) 1993-01-31

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