FI105695B - Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi - Google Patents
Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi Download PDFInfo
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- FI105695B FI105695B FI885719A FI885719A FI105695B FI 105695 B FI105695 B FI 105695B FI 885719 A FI885719 A FI 885719A FI 885719 A FI885719 A FI 885719A FI 105695 B FI105695 B FI 105695B
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- Prior art keywords
- subtilisin
- asn
- ser109
- ser218
- bacillus
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Detergent Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/036,872 US4914031A (en) | 1987-04-10 | 1987-04-10 | Subtilisin analogs |
| US3687287 | 1987-04-10 | ||
| US8801038 | 1988-03-28 | ||
| PCT/US1988/001038 WO1988008033A1 (en) | 1987-04-10 | 1988-03-28 | Subtilisin analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI885719L FI885719L (fi) | 1988-12-09 |
| FI885719A0 FI885719A0 (fi) | 1988-12-09 |
| FI105695B true FI105695B (fi) | 2000-09-29 |
Family
ID=21891131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI885719A FI105695B (fi) | 1987-04-10 | 1988-12-09 | Subtilisiinin analogeja, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä koodaava DNA-sekvenssi |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4914031A (de) |
| EP (1) | EP0309565B2 (de) |
| JP (1) | JP2590247B2 (de) |
| KR (1) | KR960006120B1 (de) |
| AT (1) | ATE119941T1 (de) |
| AU (1) | AU612653B2 (de) |
| CA (1) | CA1316473C (de) |
| DE (1) | DE3853328T3 (de) |
| DK (1) | DK175576B1 (de) |
| FI (1) | FI105695B (de) |
| IL (1) | IL85953A (de) |
| LV (1) | LV11043B (de) |
| NO (1) | NO179679C (de) |
| WO (1) | WO1988008033A1 (de) |
Families Citing this family (113)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185258A (en) * | 1984-05-29 | 1993-02-09 | Genencor International, Inc. | Subtilisin mutants |
| JP2599946B2 (ja) * | 1986-01-15 | 1997-04-16 | アムジェン，インコーポレイテツド | ズブチリシン類似体 |
| IE65767B1 (en) * | 1986-04-30 | 1995-11-15 | Genencor Int | Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors |
| US5260207A (en) * | 1987-04-06 | 1993-11-09 | Enzon Labs Inc. | Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins |
| DE353250T1 (de) * | 1987-04-06 | 1998-05-28 | Novonordisk As | Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen. |
| DK6488D0 (da) * | 1988-01-07 | 1988-01-07 | Novo Industri As | Enzymer |
| US6287841B1 (en) | 1988-02-11 | 2001-09-11 | Genencor International, Inc. | High alkaline serine protease |
| US5324653A (en) * | 1988-02-11 | 1994-06-28 | Gist-Brocades N.V. | Recombinant genetic means for the production of serine protease muteins |
| PT89702B (pt) * | 1988-02-11 | 1994-04-29 | Gist Brocades Nv | Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem |
| US5116741A (en) * | 1988-04-12 | 1992-05-26 | Genex Corporation | Biosynthetic uses of thermostable proteases |
| US5246849A (en) * | 1988-04-12 | 1993-09-21 | Enzon, Inc. | Thermally stable serine proteases |
| US5122449A (en) * | 1988-10-07 | 1992-06-16 | Eastman Kodak Company | Use of a protease in the extraction of chlamydial, gonococcal and herpes antigens |
| JPH03505976A (ja) * | 1989-05-17 | 1991-12-26 | アムジエン・インコーポレーテツド | 多重突然変異スブチリシン |
| US5665587A (en) * | 1989-06-26 | 1997-09-09 | Novo Nordisk A/S | Modified subtilisins and detergent compositions containing same |
| CA2034486A1 (en) * | 1989-06-26 | 1990-12-27 | Eric Casteleijn | Enzymatic detergent compositions |
| DK316989D0 (da) * | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| US5658871A (en) * | 1989-07-07 | 1997-08-19 | Lever Brothers Company, Division Of Conopco, Inc. | Microbial lipase muteins and detergent compositions comprising same |
| ES2144990T3 (es) * | 1989-08-25 | 2000-07-01 | Henkel Of America Inc | Enzima proteolitica alcalina y metodo de produccion. |
| US6271012B1 (en) * | 1989-10-11 | 2001-08-07 | Genencor International, Inc. | Protease muteins and their use in detergents |
| IT1239733B (it) * | 1990-02-23 | 1993-11-15 | Eniricerche Spa | Mutanti della proteasi neutra termostabili e mezzi e metodi per la loro preparazione |
| US5541062A (en) * | 1990-02-23 | 1996-07-30 | Arch Development Corporation | Methods and compositions for preparing protein processing enzymes |
| DK271490D0 (da) * | 1990-11-14 | 1990-11-14 | Novo Nordisk As | Detergentkomposition |
| US5340735A (en) * | 1991-05-29 | 1994-08-23 | Cognis, Inc. | Bacillus lentus alkaline protease variants with increased stability |
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| GB1240058A (en) * | 1968-04-12 | 1971-07-21 | Procter & Gamble | Enzyme-containing detergent compositions |
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1987
- 1987-04-10 US US07/036,872 patent/US4914031A/en not_active Expired - Lifetime
-
1988
- 1988-03-28 EP EP88904041A patent/EP0309565B2/de not_active Expired - Lifetime
- 1988-03-28 AT AT88904041T patent/ATE119941T1/de not_active IP Right Cessation
- 1988-03-28 DE DE3853328T patent/DE3853328T3/de not_active Expired - Lifetime
- 1988-03-28 JP JP63503622A patent/JP2590247B2/ja not_active Expired - Lifetime
- 1988-03-28 KR KR1019880701638A patent/KR960006120B1/ko not_active Expired - Fee Related
- 1988-03-28 WO PCT/US1988/001038 patent/WO1988008033A1/en not_active Ceased
- 1988-03-28 AU AU17016/88A patent/AU612653B2/en not_active Expired
- 1988-03-31 IL IL85953A patent/IL85953A/xx not_active IP Right Cessation
- 1988-03-31 CA CA000563171A patent/CA1316473C/en not_active Expired - Lifetime
- 1988-12-09 NO NO885484A patent/NO179679C/no not_active IP Right Cessation
- 1988-12-09 DK DK198806867A patent/DK175576B1/da not_active IP Right Cessation
- 1988-12-09 FI FI885719A patent/FI105695B/fi not_active IP Right Cessation
-
1995
- 1995-06-21 LV LVP-95-188A patent/LV11043B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3853328T3 (de) | 2002-06-06 |
| JP2590247B2 (ja) | 1997-03-12 |
| HK1007168A1 (en) | 1999-04-01 |
| EP0309565B1 (de) | 1995-03-15 |
| CA1316473C (en) | 1993-04-20 |
| EP0309565B2 (de) | 2001-08-22 |
| KR890700668A (ko) | 1989-04-26 |
| DK175576B1 (da) | 2004-12-13 |
| NO179679B (no) | 1996-08-19 |
| FI885719L (fi) | 1988-12-09 |
| EP0309565A1 (de) | 1989-04-05 |
| DE3853328D1 (de) | 1995-04-20 |
| NO179679C (no) | 1996-11-27 |
| DE3853328T2 (de) | 1995-07-27 |
| ATE119941T1 (de) | 1995-04-15 |
| US4914031A (en) | 1990-04-03 |
| NO885484L (no) | 1989-02-09 |
| DK686788A (da) | 1988-12-09 |
| AU1701688A (en) | 1988-11-04 |
| WO1988008033A1 (en) | 1988-10-20 |
| NO885484D0 (no) | 1988-12-09 |
| LV11043B (en) | 1996-06-20 |
| FI885719A0 (fi) | 1988-12-09 |
| LV11043A (lv) | 1996-02-20 |
| KR960006120B1 (ko) | 1996-05-09 |
| AU612653B2 (en) | 1991-07-18 |
| JPH01502957A (ja) | 1989-10-12 |
| IL85953A0 (en) | 1988-09-30 |
| IL85953A (en) | 1993-01-31 |
| EP0309565A4 (de) | 1990-02-05 |
| DK686788D0 (da) | 1988-12-09 |
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| FG | Patent granted |
Owner name: AMGEN INC. |
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| MA | Patent expired |