DK3089991T3 - Forbedret proteinekspression - Google Patents
Forbedret proteinekspression Download PDFInfo
- Publication number
- DK3089991T3 DK3089991T3 DK14821382T DK14821382T DK3089991T3 DK 3089991 T3 DK3089991 T3 DK 3089991T3 DK 14821382 T DK14821382 T DK 14821382T DK 14821382 T DK14821382 T DK 14821382T DK 3089991 T3 DK3089991 T3 DK 3089991T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein expression
- improved protein
- improved
- expression
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361922613P | 2013-12-31 | 2013-12-31 | |
| PCT/US2014/069019 WO2015102814A1 (en) | 2013-12-31 | 2014-12-08 | Enhanced protein expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3089991T3 true DK3089991T3 (da) | 2019-12-02 |
Family
ID=52273531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14821382T DK3089991T3 (da) | 2013-12-31 | 2014-12-08 | Forbedret proteinekspression |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10287591B2 (da) |
| EP (1) | EP3089991B1 (da) |
| JP (1) | JP6585602B2 (da) |
| CN (1) | CN106068273B (da) |
| CA (1) | CA2935066C (da) |
| DK (1) | DK3089991T3 (da) |
| MX (1) | MX2016008595A (da) |
| WO (1) | WO2015102814A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106599611B (zh) * | 2016-12-09 | 2019-04-30 | 中南大学 | 蛋白质功能标注方法及系统 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302544A (en) | 1979-10-15 | 1981-11-24 | University Of Rochester | Asporogenous mutant of B. subtilis for use as host component of HV1 system |
| US4450235A (en) | 1982-04-21 | 1984-05-22 | Cpc International Inc. | Asporogenic mutant of bacillus subtilis useful as a host in a host-vector system |
| US5310675A (en) | 1983-06-24 | 1994-05-10 | Genencor, Inc. | Procaryotic carbonyl hydrolases |
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
| WO1985000382A1 (en) | 1983-07-06 | 1985-01-31 | Gist-Brocades N.V. | Molecular cloning and expression in industrial microorganism species |
| US5763257A (en) | 1984-05-29 | 1998-06-09 | Genencor International, Inc. | Modified subtilisins having amino acid alterations |
| US5264366A (en) | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| JP2599946B2 (ja) | 1986-01-15 | 1997-04-16 | アムジェン，インコーポレイテツド | ズブチリシン類似体 |
| US4980288A (en) | 1986-02-12 | 1990-12-25 | Genex Corporation | Subtilisin with increased thermal stability |
| GB8608194D0 (en) | 1986-04-03 | 1986-05-08 | Massey Ferguson Services Nv | Valve control system |
| US5322770A (en) | 1989-12-22 | 1994-06-21 | Hoffman-Laroche Inc. | Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription |
| AU620026B2 (en) | 1987-02-27 | 1992-02-13 | Genencor International, Inc. | Molecular cloning and expression of genes encoding proteolytic enzymes |
| US4914031A (en) | 1987-04-10 | 1990-04-03 | Amgen, Inc. | Subtilisin analogs |
| DK6488D0 (da) | 1988-01-07 | 1988-01-07 | Novo Industri As | Enzymer |
| PT89702B (pt) | 1988-02-11 | 1994-04-29 | Gist Brocades Nv | Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem |
| US5665587A (en) | 1989-06-26 | 1997-09-09 | Novo Nordisk A/S | Modified subtilisins and detergent compositions containing same |
| DK97190D0 (da) | 1990-04-19 | 1990-04-19 | Novo Nordisk As | Oxidationsstabile detergentenzymer |
| US5482849A (en) | 1990-12-21 | 1996-01-09 | Novo Nordisk A/S | Subtilisin mutants |
| JP3471797B2 (ja) | 1991-05-01 | 2003-12-02 | ノボザイムス アクティーゼルスカブ | 安定化酵素及び洗剤 |
| DE4411223A1 (de) | 1994-03-31 | 1995-10-05 | Solvay Enzymes Gmbh & Co Kg | Verwendung alkalischer Proteasen in gewerblichen Textilwaschverfahren |
| AR015977A1 (es) | 1997-10-23 | 2001-05-30 | Genencor Int | Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes |
| US6835550B1 (en) | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
| US6617148B2 (en) * | 2000-06-29 | 2003-09-09 | E. I. Du Pont De Nemours And Company | Natural promoters for gene expression and metabolic monitoring in bacillus species |
| ATE495245T1 (de) | 2002-02-15 | 2011-01-15 | Danisco Us Inc | Verbesserte proteinexpression in bacillus subtilis |
| BRPI0517908A (pt) * | 2004-11-26 | 2008-10-14 | Kyowa Hakko Kogyo Kk | cepa mutante de e. coli, e, método para produzir uma substáncia útil |
| EP2210898A1 (en) * | 2006-11-29 | 2010-07-28 | Novozymes Inc. | Bacillus Licheniformis chromosome |
| US20100022861A1 (en) | 2008-07-28 | 2010-01-28 | Medtronic, Inc. | Implantable optical hemodynamic sensor including an extension member |
| AR076941A1 (es) | 2009-06-11 | 2011-07-20 | Danisco Us Inc | Cepa de bacillus para una mayor produccion de proteina |
-
2014
- 2014-12-08 JP JP2016544103A patent/JP6585602B2/ja active Active
- 2014-12-08 CA CA2935066A patent/CA2935066C/en active Active
- 2014-12-08 DK DK14821382T patent/DK3089991T3/da active
- 2014-12-08 US US15/108,074 patent/US10287591B2/en active Active
- 2014-12-08 MX MX2016008595A patent/MX2016008595A/es unknown
- 2014-12-08 WO PCT/US2014/069019 patent/WO2015102814A1/en active Application Filing
- 2014-12-08 CN CN201480076332.6A patent/CN106068273B/zh active Active
- 2014-12-08 EP EP14821382.0A patent/EP3089991B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20160319288A1 (en) | 2016-11-03 |
| CA2935066C (en) | 2022-06-21 |
| MX2016008595A (es) | 2016-10-28 |
| CN106068273A (zh) | 2016-11-02 |
| JP2017500879A (ja) | 2017-01-12 |
| EP3089991A1 (en) | 2016-11-09 |
| CA2935066A1 (en) | 2015-07-09 |
| WO2015102814A1 (en) | 2015-07-09 |
| US10287591B2 (en) | 2019-05-14 |
| JP6585602B2 (ja) | 2019-10-02 |
| CN106068273B (zh) | 2021-01-08 |
| EP3089991B1 (en) | 2019-08-28 |
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