ES2320487T3 - Pirrolopirimidinas utiles como inhibidores de proteina quinasas. - Google Patents

Pirrolopirimidinas utiles como inhibidores de proteina quinasas. Download PDF

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Publication number
ES2320487T3
ES2320487T3 ES06734381T ES06734381T ES2320487T3 ES 2320487 T3 ES2320487 T3 ES 2320487T3 ES 06734381 T ES06734381 T ES 06734381T ES 06734381 T ES06734381 T ES 06734381T ES 2320487 T3 ES2320487 T3 ES 2320487T3
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compound according
disorder
disease
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optionally substituted
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Spanish (es)
Inventor
Mark W. Ledeboer
Albert C. Pierce
Guy W. Bemis
Luc J. Farmer
Tiansheng Wang
David Messersmith
John P. Duffy
Jian Wang
Francesco G. Salituro
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Immunology (AREA)
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  • Diabetes (AREA)
  • Rheumatology (AREA)
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ES06734381T 2005-02-03 2006-02-02 Pirrolopirimidinas utiles como inhibidores de proteina quinasas. Active ES2320487T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64978105P 2005-02-03 2005-02-03
US649781P 2005-02-03

Publications (1)

Publication Number Publication Date
ES2320487T3 true ES2320487T3 (es) 2009-05-22

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ID=36498734

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ES06734381T Active ES2320487T3 (es) 2005-02-03 2006-02-02 Pirrolopirimidinas utiles como inhibidores de proteina quinasas.

Country Status (16)

Country Link
US (2) US8633205B2 (enExample)
EP (1) EP1844050B1 (enExample)
JP (2) JP5227032B2 (enExample)
KR (1) KR20070104641A (enExample)
CN (1) CN101142218B (enExample)
AT (1) ATE420883T1 (enExample)
AU (1) AU2006221065A1 (enExample)
CA (1) CA2596830A1 (enExample)
DE (1) DE602006004844D1 (enExample)
ES (1) ES2320487T3 (enExample)
IL (1) IL184898A0 (enExample)
MX (1) MX2007009429A (enExample)
NO (1) NO20074431L (enExample)
RU (1) RU2434871C2 (enExample)
WO (1) WO2006096270A1 (enExample)
ZA (1) ZA200707342B (enExample)

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US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
WO2008043031A1 (en) 2006-10-04 2008-04-10 Pharmacopeia, Inc. 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
KR20090082453A (ko) 2006-11-01 2009-07-30 버텍스 파마슈티칼스 인코포레이티드 야누스 키나제의 억제제로서 유용한 트리사이클릭 헤테로아릴 화합물
MX2009005194A (es) * 2006-11-16 2009-11-10 Pharmacopeia Llc Derivados de purina 7-sustituidos para inmunosupresion.
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