ES2170573T3 - Sistema terapeutico percutaneo que contiene d2-agonista para el tratamiento del sindrome de parkinson y metodo para su fabricacion. - Google Patents

Sistema terapeutico percutaneo que contiene d2-agonista para el tratamiento del sindrome de parkinson y metodo para su fabricacion.

Info

Publication number
ES2170573T3
ES2170573T3 ES99910359T ES99910359T ES2170573T3 ES 2170573 T3 ES2170573 T3 ES 2170573T3 ES 99910359 T ES99910359 T ES 99910359T ES 99910359 T ES99910359 T ES 99910359T ES 2170573 T3 ES2170573 T3 ES 2170573T3
Authority
ES
Spain
Prior art keywords
system containing
therapeutic system
agonist
manufacturing
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99910359T
Other languages
English (en)
Inventor
Walter Muller
James V Peck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Discovery Therapeutics Inc
Original Assignee
LTS Lohmann Therapie Systeme AG
Discovery Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7862904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2170573(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LTS Lohmann Therapie Systeme AG, Discovery Therapeutics Inc filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2170573T3 publication Critical patent/ES2170573T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Sistema terapéutico percutáneo que contiene una capa posterior inerte a los componentes de la matriz, una capa-matriz autoadhesiva, que contiene (-)-5,6,7,8-tetrahidro-6-[propil[2-(2tienil)etil]amino]-1-naftol y una lámina protectora que se quita antes de usar, caracterizado porque la capa-matriz a) contiene como base un adhesivo de polímero acuoso, a base de acrilato y/o silicona, b) posee una solubilidad para la base libre (-)5, 6, 7, 8-tetrahidro-6-[propil[2-(2-tienil)etil]amino]-1-naftol de 5 % (g/g), y c) la base libre contiene, en cantidad eficaz, 5, 6, 7, 8-tetrahidro-6-[propil[2-(2-tienil)etil]amino]-1-naftol.
ES99910359T 1998-03-30 1999-03-18 Sistema terapeutico percutaneo que contiene d2-agonista para el tratamiento del sindrome de parkinson y metodo para su fabricacion. Expired - Lifetime ES2170573T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19814084A DE19814084B4 (de) 1998-03-30 1998-03-30 D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
ES2170573T3 true ES2170573T3 (es) 2002-08-01

Family

ID=7862904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99910359T Expired - Lifetime ES2170573T3 (es) 1998-03-30 1999-03-18 Sistema terapeutico percutaneo que contiene d2-agonista para el tratamiento del sindrome de parkinson y metodo para su fabricacion.

Country Status (31)

Country Link
US (4) US6884434B1 (es)
EP (1) EP1033978B1 (es)
JP (1) JP3984785B2 (es)
KR (1) KR100432276B1 (es)
CN (1) CN1142773C (es)
AR (1) AR014778A1 (es)
AT (1) ATE210973T1 (es)
AU (1) AU746856B2 (es)
BR (1) BRPI9909313B8 (es)
CA (1) CA2326630C (es)
CZ (1) CZ297889B6 (es)
DE (4) DE19814084B4 (es)
DK (1) DK1033978T3 (es)
ES (1) ES2170573T3 (es)
FR (1) FR06C0025I2 (es)
HK (1) HK1031196A1 (es)
HU (1) HU226733B1 (es)
ID (1) ID26646A (es)
IL (1) IL138722A (es)
LU (1) LU91269I2 (es)
MY (1) MY119660A (es)
NL (1) NL300236I2 (es)
NO (3) NO325766B1 (es)
NZ (1) NZ507066A (es)
PL (1) PL193074B1 (es)
PT (1) PT1033978E (es)
SK (1) SK284618B6 (es)
TR (1) TR200002829T2 (es)
TW (1) TW579299B (es)
WO (1) WO1999049852A1 (es)
ZA (1) ZA200005261B (es)

Families Citing this family (92)

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DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
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