IS8229A - Notkun á rótigótíni við meðferð á þugnlyndi - Google Patents
Notkun á rótigótíni við meðferð á þugnlyndiInfo
- Publication number
- IS8229A IS8229A IS8229A IS8229A IS8229A IS 8229 A IS8229 A IS 8229A IS 8229 A IS8229 A IS 8229A IS 8229 A IS8229 A IS 8229A IS 8229 A IS8229 A IS 8229A
- Authority
- IS
- Iceland
- Prior art keywords
- rotigotine
- depression
- treatment
- naphthol
- prodrugs
- Prior art date
Links
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 2
- 229960003179 rotigotine Drugs 0.000 title abstract 2
- 208000020401 Depressive disease Diseases 0.000 title 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334188A DE10334188B4 (de) | 2003-07-26 | 2003-07-26 | Verwendung von Rotigotin zur Behandlung von Depressionen |
| PCT/EP2004/008168 WO2005009424A1 (de) | 2003-07-26 | 2004-07-22 | Verwendung von rotigotin zur behandlung von depressionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS8229A true IS8229A (is) | 2006-01-12 |
Family
ID=34088862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS8229A IS8229A (is) | 2003-07-26 | 2006-01-12 | Notkun á rótigótíni við meðferð á þugnlyndi |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8754119B2 (is) |
| EP (1) | EP1648432B1 (is) |
| JP (1) | JP5001651B2 (is) |
| KR (1) | KR101140510B1 (is) |
| CN (1) | CN100430050C (is) |
| AT (1) | ATE478660T1 (is) |
| AU (1) | AU2004258697B2 (is) |
| BR (1) | BRPI0413000A (is) |
| CA (1) | CA2532859C (is) |
| DE (2) | DE10334188B4 (is) |
| DK (1) | DK1648432T3 (is) |
| EA (1) | EA009784B1 (is) |
| ES (1) | ES2351190T3 (is) |
| IL (1) | IL173028A (is) |
| IS (1) | IS8229A (is) |
| MX (1) | MXPA06000782A (is) |
| NO (1) | NO335666B1 (is) |
| NZ (1) | NZ545063A (is) |
| PL (1) | PL1648432T3 (is) |
| UA (1) | UA83493C2 (is) |
| WO (1) | WO2005009424A1 (is) |
| ZA (1) | ZA200600341B (is) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| PT1426049E (pt) | 2002-12-02 | 2005-09-30 | Sanol Arznei Schwarz Gmbh | Administracao iontoforetica de rotigotina para o tratamento da doenca de parkinson |
| DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| EP1547592A1 (en) | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Intranasal formulation of rotigotine |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| US8691277B2 (en) * | 2004-09-21 | 2014-04-08 | Shandong Luye Pharmaceutical Co., Ltd. | Long acting sustained-release formulation containing dopamine receptor agonist and the preparation method thereof |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| HUE027647T2 (en) | 2007-11-28 | 2016-10-28 | Ucb Pharma Gmbh | Polymorphic form of Rotigotine |
| UA106056C2 (uk) * | 2008-12-24 | 2014-07-25 | Астразенека Аб | Сполуки 2-метил-1-феніл-2-(піридин-2-іл)пропан-1-аміну та їх застосування для лікування депресії |
| EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
| EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| SMT202400353T1 (it) | 2009-12-22 | 2024-11-15 | UCB Biopharma SRL | Polivinilpirrolidone per la stabilizzazione di una dispersione solida della forma non cristallina della rotigotina |
| US8729306B2 (en) | 2010-02-05 | 2014-05-20 | Ucb Pharma Gmbh | Process for the preparation of nitrogen substituted aminotetralins derivatives |
| CA2798815C (en) | 2010-06-25 | 2017-01-03 | Ucb Pharma Gmbh | Novel process for the preparation of nitrogen substituted aminotetralins derivatives |
| EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| WO2013075822A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system (tts) with rotigotine |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
| ES2694662T3 (es) | 2013-07-03 | 2018-12-26 | Lts Lohmann Therapie-Systeme Ag | Sistema terapéutico transdérmico con componente electrónico |
| US11426359B2 (en) | 2014-05-20 | 2022-08-30 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
| CA2948220C (en) | 2014-05-20 | 2023-06-20 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
| CA2948221C (en) | 2014-05-20 | 2022-11-22 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| US9956201B2 (en) | 2014-07-21 | 2018-05-01 | Spriaso Llc | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms |
| US10603272B2 (en) | 2015-02-27 | 2020-03-31 | Kindred Biosciences, Inc. | Stimulation of appetite and treatment of anorexia in dogs and cats |
| EP4230648A3 (en) * | 2016-07-28 | 2023-10-18 | Regeneron Pharmaceuticals, Inc. | Gpr156 variants and uses thereof |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CA3138100A1 (en) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Treatment of depression and other various disorders with psilocybin |
| PT3854388T (pt) | 2020-01-24 | 2023-12-11 | Luye Pharma Switzerland Ag | Sistema terapêutico transdérmico com o princípio ativo rotigotina e pelo menos um adesivo de silicone não resistente a aminas |
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| PT1256339E (pt) * | 2001-05-08 | 2004-02-27 | Lohmann Therapie Syst Lts | Sistema terapeutico transdermico para doenca de parkinson que induz niveis plasmaticos altos de rotigotina |
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-
2003
- 2003-07-26 DE DE10334188A patent/DE10334188B4/de not_active Expired - Fee Related
-
2004
- 2004-07-22 UA UAA200600333A patent/UA83493C2/uk unknown
- 2004-07-22 DE DE502004011581T patent/DE502004011581D1/de not_active Expired - Lifetime
- 2004-07-22 AU AU2004258697A patent/AU2004258697B2/en not_active Ceased
- 2004-07-22 NZ NZ545063A patent/NZ545063A/en not_active IP Right Cessation
- 2004-07-22 CN CNB2004800217910A patent/CN100430050C/zh not_active Expired - Fee Related
- 2004-07-22 AT AT04741204T patent/ATE478660T1/de active
- 2004-07-22 BR BRPI0413000-6A patent/BRPI0413000A/pt active Search and Examination
- 2004-07-22 EP EP04741204A patent/EP1648432B1/de not_active Revoked
- 2004-07-22 KR KR1020067001785A patent/KR101140510B1/ko not_active Expired - Fee Related
- 2004-07-22 PL PL04741204T patent/PL1648432T3/pl unknown
- 2004-07-22 US US10/565,699 patent/US8754119B2/en not_active Expired - Fee Related
- 2004-07-22 WO PCT/EP2004/008168 patent/WO2005009424A1/de active Application Filing
- 2004-07-22 CA CA2532859A patent/CA2532859C/en not_active Expired - Fee Related
- 2004-07-22 MX MXPA06000782A patent/MXPA06000782A/es active IP Right Grant
- 2004-07-22 DK DK04741204.4T patent/DK1648432T3/da active
- 2004-07-22 JP JP2006521476A patent/JP5001651B2/ja not_active Expired - Fee Related
- 2004-07-22 ES ES04741204T patent/ES2351190T3/es not_active Expired - Lifetime
- 2004-07-22 EA EA200600222A patent/EA009784B1/ru not_active IP Right Cessation
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2006
- 2006-01-09 IL IL173028A patent/IL173028A/en not_active IP Right Cessation
- 2006-01-12 IS IS8229A patent/IS8229A/is unknown
- 2006-02-21 NO NO20060846A patent/NO335666B1/no not_active IP Right Cessation
- 2006-09-01 ZA ZA200600341A patent/ZA200600341B/xx unknown
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