BR0309259A - Terapia combinada para o tratamento de doença de parkinson com inibidores de ciclooxigenase-2 (cox 2) - Google Patents

Terapia combinada para o tratamento de doença de parkinson com inibidores de ciclooxigenase-2 (cox 2)

Info

Publication number
BR0309259A
BR0309259A BR0309259-3A BR0309259A BR0309259A BR 0309259 A BR0309259 A BR 0309259A BR 0309259 A BR0309259 A BR 0309259A BR 0309259 A BR0309259 A BR 0309259A
Authority
BR
Brazil
Prior art keywords
cyclooxygenase
inhibitors
treatment
cox
parkinson
Prior art date
Application number
BR0309259-3A
Other languages
English (en)
Inventor
Diane T Stephenson
Peter C Isakson
Timothy J Maziasz
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0309259A publication Critical patent/BR0309259A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"TERAPIA COMBINADA PARA O TRATAMENTO DE DOENçA DE PARKINSON COM INIBIDORES DE CICLOOXIGENASE-2 (COX 2)". A invenção refere-se a um método de tratamento, prevenção ou inibição da DP, num indivíduo que necessite de tal tratamento, inibição ou prevenção. O método compreende o tratamento do indivíduo com um ou mais inibidores seletivos de ciclooxigenase-2, ou isómeros, sais farmaceuticamente aceitáveis, ésteres, ou prodrogas dos mesmos, em combinação com um ou mais segundos fármacos, em que a quantidade de inibidor(es) seletivo(s) de ciclooxigenase-2, ou isómero(s) ou sal(ais) farmaceuticamente aceitável(eis), éster(es), ou prodroga(s) do(s) mesmo(s), em combinação com a quantidade do(s) segundo(s) fármaco(s), constitui uma quantidade eficaz para tratamento, inibição ou prevenção da DP.
BR0309259-3A 2002-04-18 2003-04-14 Terapia combinada para o tratamento de doença de parkinson com inibidores de ciclooxigenase-2 (cox 2) BR0309259A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37331102P 2002-04-18 2002-04-18
PCT/US2003/011269 WO2003088958A2 (en) 2002-04-18 2003-04-14 Combinations of cox-2 inhibitors and other agents for the treatment of parkinson’s disease

Publications (1)

Publication Number Publication Date
BR0309259A true BR0309259A (pt) 2005-02-09

Family

ID=29251013

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0309259-3A BR0309259A (pt) 2002-04-18 2003-04-14 Terapia combinada para o tratamento de doença de parkinson com inibidores de ciclooxigenase-2 (cox 2)

Country Status (8)

Country Link
US (1) US20040034083A1 (pt)
EP (1) EP1494664A2 (pt)
JP (1) JP2005528403A (pt)
AU (1) AU2003223579A1 (pt)
BR (1) BR0309259A (pt)
CA (1) CA2481934A1 (pt)
MX (1) MXPA04009352A (pt)
WO (1) WO2003088958A2 (pt)

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SI1663197T1 (sl) 2003-09-09 2008-06-30 Biogen Idec Internat Gmbh Uporaba derivatov fumarne kisline za zdravljenje sräśne insuficience in astme
DE10359528A1 (de) * 2003-12-18 2005-07-28 Schwarz Pharma Ag (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
EP1547592A1 (en) * 2003-12-23 2005-06-29 Schwarz Pharma Ag Intranasal formulation of rotigotine
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
WO2006071184A1 (en) * 2004-12-28 2006-07-06 Astrazeneca Ab Aryl sulphonamide modulators
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Also Published As

Publication number Publication date
WO2003088958A2 (en) 2003-10-30
CA2481934A1 (en) 2003-10-30
JP2005528403A (ja) 2005-09-22
AU2003223579A1 (en) 2003-11-03
AU2003223579A8 (en) 2003-11-03
EP1494664A2 (en) 2005-01-12
MXPA04009352A (es) 2005-01-25
US20040034083A1 (en) 2004-02-19
WO2003088958A3 (en) 2004-08-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]