ES2118249T3 - Parche que contiene dexpanthenol para la aplicacion percutanea de hormonas esteroideas. - Google Patents

Parche que contiene dexpanthenol para la aplicacion percutanea de hormonas esteroideas.

Info

Publication number
ES2118249T3
ES2118249T3 ES93919070T ES93919070T ES2118249T3 ES 2118249 T3 ES2118249 T3 ES 2118249T3 ES 93919070 T ES93919070 T ES 93919070T ES 93919070 T ES93919070 T ES 93919070T ES 2118249 T3 ES2118249 T3 ES 2118249T3
Authority
ES
Spain
Prior art keywords
dexpanthenol
steroid hormones
containing patch
percutaneous application
self
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93919070T
Other languages
English (en)
Inventor
Michael Roreger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2118249T3 publication Critical patent/ES2118249T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/16Nitrogen-containing compounds
    • C08K5/20Carboxylic acid amides
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09JADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J123/00Adhesives based on homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Adhesives based on derivatives of such polymers
    • C09J123/02Adhesives based on homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Adhesives based on derivatives of such polymers not modified by chemical after-treatment
    • C09J123/04Homopolymers or copolymers of ethene
    • C09J123/08Copolymers of ethene
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C08L2666/04Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN EMPLASTO AUTOADHESIVO PARA APLICACION TRANSDERMAL DE HORMONA ESTEROIDE ACTIVA DE FORMA SISTEMATICA, CON UNA CAPA ADHESIVA PERMEABLE A LA SUSTANCIA ACTIVA, UNA CAPA AUTOADHESIVA QUE CONTIENE LA SUSTANCIA ACTIVA Y UNA CAPA DE PROTECCION DESMONTABLE RECUBIERTA PARA LA APLICACION SOBRE LA PIEL. SE CARACTERIZA PORQUE LA CAPA AUTOADHESIVA, QUE CONTIENE SUSTANCIA ACTIVA, CONTIENE A SU VEZ UN PEGAMENTO DE ADHERENCIA CON UNA TEMPERATURA DE ELABORACION ENTRE 60 Y 100 Y DEXPANTENOL EN UNA CONCENTRACION DESDE 15 HASTA 25 % EN PESO.
ES93919070T 1992-09-12 1993-08-16 Parche que contiene dexpanthenol para la aplicacion percutanea de hormonas esteroideas. Expired - Lifetime ES2118249T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230588A DE4230588C1 (de) 1992-09-12 1992-09-12 Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
ES2118249T3 true ES2118249T3 (es) 1998-09-16

Family

ID=6467830

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93919070T Expired - Lifetime ES2118249T3 (es) 1992-09-12 1993-08-16 Parche que contiene dexpanthenol para la aplicacion percutanea de hormonas esteroideas.

Country Status (25)

Country Link
US (1) US5662923A (es)
EP (1) EP0659081B1 (es)
JP (1) JPH08508238A (es)
KR (1) KR100297548B1 (es)
AT (1) ATE163854T1 (es)
AU (1) AU683017B2 (es)
CZ (1) CZ283589B6 (es)
DE (2) DE4230588C1 (es)
DK (1) DK0659081T3 (es)
ES (1) ES2118249T3 (es)
FI (1) FI112322B (es)
GR (1) GR3026503T3 (es)
HR (1) HRP931107B1 (es)
HU (1) HUT75779A (es)
IL (1) IL106512A (es)
MY (1) MY110531A (es)
NO (1) NO308235B1 (es)
NZ (1) NZ255352A (es)
PH (1) PH31298A (es)
PL (1) PL174605B1 (es)
SI (1) SI9300471A (es)
SK (1) SK280493B6 (es)
WO (1) WO1994006436A1 (es)
YU (1) YU58393A (es)
ZA (1) ZA936687B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19700913C2 (de) * 1997-01-14 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Hormonen
DE19720777A1 (de) 1997-05-17 1998-11-19 Barbara Panzner Mehrphasenauflagesystem mit Verpackung
DE19828273B4 (de) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
US6241998B1 (en) 1999-02-02 2001-06-05 Acutek International Dermatological patch
DE19911262C2 (de) * 1999-03-13 2003-04-10 Scs Skin Care Systems Gmbh Vorrichtung zur Abgabe kosmetischer Wirkstoffe
KR100622332B1 (ko) * 1999-04-01 2006-09-13 알자 코포레이션 폴리우레탄 약물 리저버를 함유하는 경피 약물 수송 장치
US6465004B1 (en) * 1999-06-05 2002-10-15 Noven Pharmaceuticals, Inc. Solubility enhancement of drugs in transdermal drug delivery systems and methods of use
WO2001052823A2 (en) * 2000-01-20 2001-07-26 Noven Pharmaceuticals, Inc. Compositions to effect the release profile in the transdermal administration of drugs
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
DE10118282A1 (de) 2001-04-12 2002-12-05 Lohmann Therapie Syst Lts Haftkleber auf Basis von Ethylen-Vinylacetat-Copolymeren und Klebharzen, für medizinische Verwendungszwecke
DE10121471A1 (de) * 2001-05-02 2002-11-07 Beiersdorf Ag Oberflächendotierte wirkstoffhaltige Pflaster
CA2489865C (en) 2002-06-25 2012-05-08 Acrux Dds Pty Ltd Transdermal delivery rate control using amorphous pharmaceutical compositions
DE10256774A1 (de) * 2002-12-05 2004-06-24 Lts Lohmann Therapie-Systeme Ag Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption
DE10304988A1 (de) * 2003-02-07 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten
JP2004277345A (ja) * 2003-03-17 2004-10-07 Daikyo Yakuhin Kogyo Kk 硬膏剤及びその製造法
DE202004000552U1 (de) * 2004-01-15 2004-04-01 Ivoclar Vivadent Ag Mittel zum Bleichen von Zähnen
DE102008006210A1 (de) * 2008-01-26 2009-07-30 Lts Lohmann Therapie-Systeme Ag Kosmetisches Fixierpflaster
GB2502554B (en) * 2012-05-30 2016-02-03 Henkel Ireland Ltd Primers
CN103720677A (zh) * 2014-01-15 2014-04-16 桂林安和药业有限公司 可重复揭贴且可重复涂布药物的贴膏
US10226419B2 (en) * 2014-09-08 2019-03-12 ProMed Pharma, LLC Methods for manufacturing implants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS615012A (ja) * 1984-06-11 1986-01-10 Dai Ichi Seiyaku Co Ltd 貼付剤
AU4805085A (en) * 1984-09-05 1986-03-24 Schering Aktiengesellschaft Mittel zur behandlung von androgenisierungserscheinungen und verwendung von antiandrogenen zur herstellung des mittels
JPH0816053B2 (ja) * 1986-12-04 1996-02-21 大正製薬株式会社 貼付剤の製造方法
US4788062A (en) * 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
CH674618A5 (es) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US4814168A (en) * 1988-03-04 1989-03-21 Noven Pharmaceuticals, Inc. Transdermal multipolymer drug delivery system
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
DE3902013A1 (de) * 1989-01-25 1990-09-20 Knoll Ag Pflaster zur transdermalen anwendung
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster

Also Published As

Publication number Publication date
GR3026503T3 (en) 1998-07-31
JPH08508238A (ja) 1996-09-03
MY110531A (en) 1998-07-31
IL106512A (en) 1997-07-13
CZ63795A3 (en) 1995-10-18
FI951169L (fi) 1995-03-13
FI112322B (fi) 2003-11-28
PH31298A (en) 1998-07-06
NZ255352A (en) 1996-08-27
SK280493B6 (sk) 2000-03-13
AU4948493A (en) 1994-04-12
DK0659081T3 (da) 1999-01-04
KR950703343A (ko) 1995-09-20
ATE163854T1 (de) 1998-03-15
CZ283589B6 (cs) 1998-05-13
FI951169A0 (fi) 1995-03-13
IL106512A0 (en) 1993-11-15
NO950931D0 (no) 1995-03-10
SK32795A3 (en) 1995-07-11
DE59308256D1 (de) 1998-04-16
EP0659081A1 (de) 1995-06-28
EP0659081B1 (de) 1998-03-11
HRP931107A2 (en) 1994-12-31
US5662923A (en) 1997-09-02
AU683017B2 (en) 1997-10-30
DE4230588C1 (de) 1993-10-07
HRP931107B1 (en) 1999-12-31
PL174605B1 (pl) 1998-08-31
KR100297548B1 (ko) 2001-10-24
WO1994006436A1 (de) 1994-03-31
ZA936687B (en) 1994-04-29
NO308235B1 (no) 2000-08-21
HUT75779A (en) 1997-05-28
HU9500729D0 (en) 1995-04-28
PL307786A1 (en) 1995-06-26
NO950931L (no) 1995-03-10
SI9300471A (en) 1994-03-31
YU58393A (sh) 1996-07-24

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