ES2047512T3 - Procedimiento de preparacion de un parche para la liberacion transdermal retardada de nitroglicerina. - Google Patents

Procedimiento de preparacion de un parche para la liberacion transdermal retardada de nitroglicerina.

Info

Publication number
ES2047512T3
ES2047512T3 ES88112632T ES88112632T ES2047512T3 ES 2047512 T3 ES2047512 T3 ES 2047512T3 ES 88112632 T ES88112632 T ES 88112632T ES 88112632 T ES88112632 T ES 88112632T ES 2047512 T3 ES2047512 T3 ES 2047512T3
Authority
ES
Spain
Prior art keywords
nitroglycerin
pct
nitroglycerine
patch
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88112632T
Other languages
English (en)
Inventor
Halvor Jaeger
Hans-Rainer Hoffmann
Reinhold Meconi
Robert-Peter Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25859261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2047512(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2047512T3 publication Critical patent/ES2047512T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Materials Engineering (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL INVENTO SE REFIERE A UN DISPOSITIVO PARA LA CESION CONTROLADA DE NITROGLICERINA EN LA PIEL ANIMAL O HUMANA EN FORMA DE EMPLASTO CON UNA CPA TRASERA IMPERMEABLE PARA LA NITROGLICERINA, UN DEPOSITO DE UNA O VARIAS PARTES CONTENIENDO DISTRIBUCIONES REGULARES O IRREGULARES DE NITROGLICERINA ADHESIVA Y UNA CAPA PROTECTORA DESPRENDIBLE IMPERMEABLE PARA LA NITROGLICERINA. EL DEPOSITO CON APLICACION DE GLUTEN FUNDIDO ADHESIVO SE PREPARA CON UNA TEMPERATURA DE ELABORACION ENTRE 40 Y 80 C, ASI COMO UN PROCEDIMIENTO PARA SU PREPARACION CON APLICACION CONTINUA O DISCONTINUA DE UNOS GLUTEN ADHESIVOS FUNDIDOS QUE CONTIENEN NITROGLICERINA Y A UNA TEMPERATURA ENTRE 40 Y 80 C SOBRE EL MATERIAL Y EN TODO CASO APLICACION DE UNAS CAPAS PROTECTORAS.
ES88112632T 1987-09-01 1988-08-03 Procedimiento de preparacion de un parche para la liberacion transdermal retardada de nitroglicerina. Expired - Lifetime ES2047512T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3729165 1987-09-01
DE19873743946 DE3743946A1 (de) 1987-09-01 1987-12-23 Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung

Publications (1)

Publication Number Publication Date
ES2047512T3 true ES2047512T3 (es) 1994-03-01

Family

ID=25859261

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88112632T Expired - Lifetime ES2047512T3 (es) 1987-09-01 1988-08-03 Procedimiento de preparacion de un parche para la liberacion transdermal retardada de nitroglicerina.

Country Status (25)

Country Link
US (1) US5126144A (es)
EP (1) EP0305758B1 (es)
JP (1) JP2795862B2 (es)
KR (1) KR970006446B1 (es)
AT (1) ATE98878T1 (es)
AU (1) AU636836B2 (es)
CA (1) CA1329363C (es)
CZ (1) CZ282393B6 (es)
DD (1) DD282182A5 (es)
DE (2) DE3743946A1 (es)
DK (1) DK210489D0 (es)
ES (1) ES2047512T3 (es)
FI (1) FI96578C (es)
HU (1) HU205250B (es)
IE (1) IE64538B1 (es)
IL (1) IL87539A0 (es)
MY (1) MY104914A (es)
NO (1) NO178685C (es)
NZ (1) NZ225916A (es)
PH (1) PH25354A (es)
PL (1) PL163711B1 (es)
PT (1) PT88379B (es)
SK (1) SK279297B6 (es)
WO (1) WO1989001788A1 (es)
YU (1) YU47290B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
US5306502A (en) * 1987-09-01 1994-04-26 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for delivering nitroglycerin to the skin, processes for the production thereof and the use thereof
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
DE4031881C2 (de) * 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
DE4110027C2 (de) * 1991-03-27 1996-08-29 Lohmann Therapie Syst Lts Verfahren zur Konfektionierung transdermaler therapeutischer Pflaster
CA2075517C (en) * 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
US6010715A (en) * 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
DE4224325C1 (de) * 1992-07-23 1994-02-10 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung
DE4301781C2 (de) * 1993-01-23 1995-07-20 Lohmann Therapie Syst Lts Nitroglycerinhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung
DE4313928C2 (de) * 1993-04-28 1996-09-19 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur kontrollierten Abgabe von Pilocarpin an die Haut, Verfahren zu seiner Herstellung und seine Verwendung
DE4336557C2 (de) * 1993-05-06 1997-07-17 Lohmann Therapie Syst Lts Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung
DE4332094C2 (de) * 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
US5380760A (en) * 1993-11-19 1995-01-10 Minnesota Mining And Manufacturing Company Transdermal prostaglandin composition
DE4400770C1 (de) * 1994-01-13 1995-02-02 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster zur Abgabe von Estradiol mit mindestens einem Penetrationsverstärker, Verfahren zu seiner Herstellung und seine Verwendung
DE4403487C2 (de) * 1994-02-04 2003-10-16 Lohmann Therapie Syst Lts Arznei-Pflaster mit UV-vernetzbaren Acrylat-Copolymeren
MX9702750A (es) 1994-10-28 1997-09-30 Kimberly Clark Wordlwide Inc Articulo absorbente autoadherente.
DE19500662C2 (de) * 1995-01-12 2001-04-26 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster und seine Verwendung
US5688523A (en) * 1995-03-31 1997-11-18 Minnesota Mining And Manufacturing Company Method of making a pressure sensitive skin adhesive sheet material
AU6264198A (en) * 1997-02-06 1998-08-26 Crysteco, Inc. Method and apparatus for growing crystals
DE19825499C2 (de) 1998-06-08 2003-07-17 Beiersdorf Ag Wirkstoffhaltige Pflaster
DE19828273B4 (de) 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
DE19834007C1 (de) 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
US6328988B1 (en) * 1999-04-23 2001-12-11 Rutgers, The State University Of New Jersey Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules
DE10001546A1 (de) 2000-01-14 2001-07-19 Beiersdorf Ag Verfahren zur kontinuierlichen Herstellung und Beschichtung von Selbstlebemassen auf Basis von Polyisobutylen mit mindestens einem pharmazeutischen Wirkstoff
CA2453216A1 (en) * 2001-07-12 2003-01-23 Rutgers, The State University Of New Jersey Amphiphilic star-like macromolecules for drug delivery
US20070050883A1 (en) * 2002-01-18 2007-03-08 Matich Ronald D Face mask with seal and neutralizer
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
DE10236319A1 (de) * 2002-08-08 2004-02-19 Beiersdorf Ag Hautfreundliche Wirkstoffpflaster auf der Basis von SBC mit mindestens einem pharmazeutischen Wirkstoff mit einem Gehalt von mindestens 34 Gew.-% und dessen Herstellung
US20050191339A1 (en) * 2002-08-08 2005-09-01 Beiersdorf Ag Skin friendly active ingredient plaster based on SBC, containing at least 34 WT.% of a pharmaceutical active ingredient and production thereof
JP2004277345A (ja) * 2003-03-17 2004-10-07 Daikyo Yakuhin Kogyo Kk 硬膏剤及びその製造法
DE102005053909A1 (de) * 2005-05-13 2006-11-16 Beiersdorf Ag Selbstklebende Hautauflage und Kombinationsset zur kosmetischen Hautpflege

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD145004A3 (de) * 1978-09-25 1980-11-19 Reinhard Huettenrauch Verfahren zur herstellung fester a zneiformen
GB2118040A (en) * 1982-02-15 1983-10-26 Hoechst Uk Ltd Oral anti-diabetic preparation
JPS58141225A (ja) * 1982-02-16 1983-08-22 Takasago Corp 芳香材用樹脂組成物
AU560710B2 (en) * 1983-04-27 1987-04-16 Lohmann Gmbh & Co. Kg. Pharmaceutical product
US4564364A (en) * 1983-05-26 1986-01-14 Alza Corporation Active agent dispenser
GB8328279D0 (en) * 1983-10-22 1983-11-23 Smith & Nephew Res Polymer blend films
US4701509A (en) * 1984-09-17 1987-10-20 Johnson & Johnson Products, Inc. N-vinyl caprolactam-containing hot melt adhesives
DE3587616D1 (de) * 1984-12-22 1993-11-11 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster.
EP0204968B1 (de) * 1985-05-24 1989-09-27 Beiersdorf Aktiengesellschaft Nitro-Pflaster
JPS6249848A (ja) * 1985-08-30 1987-03-04 三金工業株式会社 口腔内装着物
US4797284A (en) * 1986-03-12 1989-01-10 Merck & Co., Inc. Transdermal drug delivery system
DE3629304A1 (de) * 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
US4840796A (en) * 1988-04-22 1989-06-20 Dow Corning Corporation Block copolymer matrix for transdermal drug release

Also Published As

Publication number Publication date
DK210489A (da) 1989-04-28
MY104914A (en) 1994-07-30
NO891508L (no) 1989-04-12
FI892054A0 (fi) 1989-04-28
YU166388A (sh) 1992-09-07
WO1989001788A1 (en) 1989-03-09
PL163711B1 (pl) 1994-04-29
AU2253188A (en) 1989-03-31
US5126144A (en) 1992-06-30
NO178685C (no) 1996-05-15
EP0305758B1 (de) 1993-12-22
CZ282393B6 (cs) 1997-07-16
AU636836B2 (en) 1993-05-13
CA1329363C (en) 1994-05-10
DE3743946C2 (es) 1991-06-13
JPH02500595A (ja) 1990-03-01
DD282182A5 (de) 1990-09-05
KR970006446B1 (ko) 1997-04-28
ATE98878T1 (de) 1994-01-15
FI96578B (fi) 1996-04-15
PT88379A (pt) 1989-07-31
NO891508D0 (no) 1989-04-12
NO178685B (no) 1996-02-05
DE3743946A1 (de) 1989-03-09
IE64538B1 (en) 1995-08-23
IL87539A0 (en) 1989-01-31
SK279297B6 (sk) 1998-09-09
HU884719D0 (en) 1990-02-28
FI892054A (fi) 1989-04-28
HUT53545A (en) 1990-11-28
KR890701141A (ko) 1989-12-19
EP0305758A1 (de) 1989-03-08
IE882555L (en) 1989-03-01
YU47290B (sh) 1995-01-31
DK210489D0 (da) 1989-04-28
PH25354A (en) 1991-05-13
DE3886478D1 (de) 1994-02-03
FI96578C (fi) 1996-07-25
JP2795862B2 (ja) 1998-09-10
CS587288A3 (en) 1992-12-16
NZ225916A (en) 1990-03-27
PL274488A1 (en) 1989-05-02
HU205250B (en) 1992-04-28
PT88379B (pt) 1994-06-30

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