KR890701141A - 니트로글리세린 조절 공급기재(Apparatus for the controlled delivery), 그 제조방법 및 그 용도 - Google Patents

니트로글리세린 조절 공급기재(Apparatus for the controlled delivery), 그 제조방법 및 그 용도

Info

Publication number
KR890701141A
KR890701141A KR1019890700738A KR890700738A KR890701141A KR 890701141 A KR890701141 A KR 890701141A KR 1019890700738 A KR1019890700738 A KR 1019890700738A KR 890700738 A KR890700738 A KR 890700738A KR 890701141 A KR890701141 A KR 890701141A
Authority
KR
South Korea
Prior art keywords
weight
nitroglycerin
substrate
adhesive contact
hot melt
Prior art date
Application number
KR1019890700738A
Other languages
English (en)
Other versions
KR970006446B1 (ko
Inventor
할포 자에거
한스-라이너 호프만
라인홀트 메코니
로베르트-페터 클레인
Original Assignee
호프만,마쓰
엘테에스 로오만 데라피-지스테메 게엠베하 운트 콤퍼니 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25859261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR890701141(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 호프만,마쓰, 엘테에스 로오만 데라피-지스테메 게엠베하 운트 콤퍼니 카게 filed Critical 호프만,마쓰
Publication of KR890701141A publication Critical patent/KR890701141A/ko
Application granted granted Critical
Publication of KR970006446B1 publication Critical patent/KR970006446B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements

Abstract

내용 없음

Description

니트로글리세린 조절 공급기재(Apparatus for the controlled delivery), 그 제조방법 및 그 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 니트로글리세린 저장소가 비치된 본발명 기재의 단면도이고, 제 2 도는 니트로글리세린 저장소가 비치된 본 발명의 다른 공급기재의 단면도이고, 제 3 도는 니트로글리세린 저장소가 없는 본 발명의 다른 공급 기재의 단면도이다.

Claims (7)

  1. 40°내지 80℃, 바람직하기로는 40˚ 내지 60℃, 특히 바람직하기로는 40°내지 55℃의 처리온도를 가진 열용융 접착성 접촉물을 사용하여 제조한 저장소를 특징으로 하는, 니트로글리세린 불투과성 배면층과, 규칙 또는 불규칙 분포된 접착성 접촉물 니트로글리세린 저장소와 임의로 니트로글리세린 불투과성 제거용 보호층으로 이루어진, 사람 또는 동물 피부에 니트로글리세린을 조절 공급하는 기재.
  2. 제 1 항에 있어서, 열용융 접착성 접촉물이 스티렌 - 이소프렌 - 시티렌 블럭 중합체, 폴리카푸토락톤, 에틸렌 - 비닐아세테이트 코폴리머, 폴리우레탄, 폴리에폭시드, 폴리이소부텐, 폴리비닐에테르, 그리고 임의로 점착제(tackifier), 가소제, 충전제, 항에이저(antiager), 릭소트로피제(thixotropic agent)로 제조됨을 특징으로 하는 기재.
  3. 제 1 항 또는 제 2 항에 있어서, 열용융 접착성 접촉물이 중합체 10 내지 100중량%, 바람직하기로는 20 내지 80중량%, 특히 바람직하기로는 20 내지 50중량%, 가소제 10 내지 80중량%, 바람직하기로는 15 내지 60중량%, 점착제 10 내지 80중량%, 바람직하기로는 15 내지 60중량%, 그리고 임의로 항에이저 0.1 내지 5중량%와 임의로 충전제 0 내지 70중량%로 이루어지고 총량이 100중량% 되게함을 특징으로 하는 기재.
  4. 40°내지 80℃, 바람직하기로는 40℃ 내지 60℃, 특히 바람직하기로는 40°내지 55℃의 온도에서 니트로글리세린 함유 열용융 접착성 접촉물의 용융물을 담체에 연속 또는 불연속적으로 도입하고 임으로 보호층 물질을 적용함을 특징으로 하는 제 1 항 내지 제 3 항의 기재를 제조하는 방법.
  5. 40°내지 80℃, 바람직하기로는 40℃ 내지 60℃, 특히 바람직하기로는 45°내지 55℃의 온도에서 니트로글리세린 함유 열용융 접착성 접촉물의 용융물을 보호층 물질에 연속 또는 불연속적으로 도입하고 임의로 담체를 적용함을 특징으로 하는 제 1 항 내지 제 3 항의 기재.
  6. 기재의 조성성분, 열용융 접착성 접촉물을 50°내지 80℃의 처리온도에서 압출(extrusion), 주입(pouring), 롤러처리, 나이프 코팅(knife coating), 분무 또는 압착(press) 공정에 의해 형성시킴을 특징으로 하는 제 1 항 내지 제 3 항의 기재를 제조하는 방법.
  7. 제 1 항 또는 제 3 항의 기재를 사람 또는 동물의 치료기재로 사용하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890700738A 1987-09-01 1988-08-03 니트로글리세린 조절 공급기재(Apparatus for the controlled delivery) , 그 제조방법 및 그 용도 KR970006446B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE3729165 1987-09-01
DEP3729165.3 1987-09-01
DE19873743946 DE3743946A1 (de) 1987-09-01 1987-12-23 Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
DEP3743946.4 1987-12-23
PCT/DE1988/000478 WO1989001788A1 (en) 1987-09-01 1988-08-03 Device for release of nitroglycerine onto the skin, process for its manufacture and use thereof

Publications (2)

Publication Number Publication Date
KR890701141A true KR890701141A (ko) 1989-12-19
KR970006446B1 KR970006446B1 (ko) 1997-04-28

Family

ID=25859261

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890700738A KR970006446B1 (ko) 1987-09-01 1988-08-03 니트로글리세린 조절 공급기재(Apparatus for the controlled delivery) , 그 제조방법 및 그 용도

Country Status (25)

Country Link
US (1) US5126144A (ko)
EP (1) EP0305758B1 (ko)
JP (1) JP2795862B2 (ko)
KR (1) KR970006446B1 (ko)
AT (1) ATE98878T1 (ko)
AU (1) AU636836B2 (ko)
CA (1) CA1329363C (ko)
CZ (1) CZ282393B6 (ko)
DD (1) DD282182A5 (ko)
DE (2) DE3743946A1 (ko)
DK (1) DK210489D0 (ko)
ES (1) ES2047512T3 (ko)
FI (1) FI96578C (ko)
HU (1) HU205250B (ko)
IE (1) IE64538B1 (ko)
IL (1) IL87539A0 (ko)
MY (1) MY104914A (ko)
NO (1) NO178685C (ko)
NZ (1) NZ225916A (ko)
PH (1) PH25354A (ko)
PL (1) PL163711B1 (ko)
PT (1) PT88379B (ko)
SK (1) SK279297B6 (ko)
WO (1) WO1989001788A1 (ko)
YU (1) YU47290B (ko)

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Also Published As

Publication number Publication date
KR970006446B1 (ko) 1997-04-28
FI96578B (fi) 1996-04-15
DE3743946A1 (de) 1989-03-09
DE3743946C2 (ko) 1991-06-13
YU47290B (sh) 1995-01-31
DE3886478D1 (de) 1994-02-03
HUT53545A (en) 1990-11-28
YU166388A (sh) 1992-09-07
CZ282393B6 (cs) 1997-07-16
DK210489A (da) 1989-04-28
PH25354A (en) 1991-05-13
NO891508L (no) 1989-04-12
EP0305758A1 (de) 1989-03-08
FI96578C (fi) 1996-07-25
PL163711B1 (pl) 1994-04-29
PL274488A1 (en) 1989-05-02
IE882555L (en) 1989-03-01
IE64538B1 (en) 1995-08-23
PT88379A (pt) 1989-07-31
MY104914A (en) 1994-07-30
FI892054A (fi) 1989-04-28
NO178685B (no) 1996-02-05
WO1989001788A1 (en) 1989-03-09
HU884719D0 (en) 1990-02-28
ES2047512T3 (es) 1994-03-01
NZ225916A (en) 1990-03-27
CS587288A3 (en) 1992-12-16
JPH02500595A (ja) 1990-03-01
HU205250B (en) 1992-04-28
JP2795862B2 (ja) 1998-09-10
DK210489D0 (da) 1989-04-28
SK279297B6 (sk) 1998-09-09
ATE98878T1 (de) 1994-01-15
AU2253188A (en) 1989-03-31
NO891508D0 (no) 1989-04-12
NO178685C (no) 1996-05-15
PT88379B (pt) 1994-06-30
AU636836B2 (en) 1993-05-13
EP0305758B1 (de) 1993-12-22
DD282182A5 (de) 1990-09-05
US5126144A (en) 1992-06-30
CA1329363C (en) 1994-05-10
FI892054A0 (fi) 1989-04-28
IL87539A0 (en) 1989-01-31

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