ES2177290T3 - Sistema de administracion transdermica con hormonas e inhibidores de cristalizacion. - Google Patents
Sistema de administracion transdermica con hormonas e inhibidores de cristalizacion.Info
- Publication number
- ES2177290T3 ES2177290T3 ES99927904T ES99927904T ES2177290T3 ES 2177290 T3 ES2177290 T3 ES 2177290T3 ES 99927904 T ES99927904 T ES 99927904T ES 99927904 T ES99927904 T ES 99927904T ES 2177290 T3 ES2177290 T3 ES 2177290T3
- Authority
- ES
- Spain
- Prior art keywords
- transdermal administration
- administration system
- hormones
- crystallization inhibitors
- estradiol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
- Y10S977/939—Electron emitter, e.g. spindt emitter tip coated with nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Sistema de administración transdérmica en forma de apósito para la transferencia controlada de estradiol en combinación con acetato de noretisterona, constituido por una capa superior, un reservorio sobresaturado de principios activos unido a ella, que contiene estradiol y acetato de noretisterona, el cual está fabricado a base de adhesivos de contacto de poliacrilato e inhibidores de cristalización, y una capa protectora amovible, caracterizado por ser el inhibidor de cristalización un polímero que contiene grupos amino.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19828273A DE19828273B4 (de) | 1998-06-25 | 1998-06-25 | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2177290T3 true ES2177290T3 (es) | 2002-12-01 |
Family
ID=7871950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99927904T Expired - Lifetime ES2177290T3 (es) | 1998-06-25 | 1999-06-08 | Sistema de administracion transdermica con hormonas e inhibidores de cristalizacion. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6899894B1 (es) |
EP (1) | EP1089719B1 (es) |
JP (1) | JP2002518430A (es) |
KR (1) | KR100550888B1 (es) |
CN (1) | CN1148172C (es) |
AR (1) | AR019715A1 (es) |
AT (1) | ATE215819T1 (es) |
AU (1) | AU768755B2 (es) |
BR (1) | BR9912210A (es) |
CA (1) | CA2335582C (es) |
CZ (1) | CZ300707B6 (es) |
DE (2) | DE19828273B4 (es) |
DK (1) | DK1089719T3 (es) |
ES (1) | ES2177290T3 (es) |
HU (1) | HUP0102498A3 (es) |
IL (2) | IL140434A0 (es) |
NZ (1) | NZ509015A (es) |
PL (1) | PL193080B1 (es) |
PT (1) | PT1089719E (es) |
TR (1) | TR200003839T2 (es) |
TW (1) | TW533084B (es) |
WO (1) | WO1999066901A2 (es) |
ZA (1) | ZA200007751B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE10025971B4 (de) * | 2000-05-25 | 2004-09-02 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System in Plasterform mit verminderter Tendenz zur Wirkstoffkristallisation und seine Verwendung |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US6750291B2 (en) * | 2002-04-12 | 2004-06-15 | Pacific Corporation | Film-forming agent for drug delivery and preparation for percutaneous administration containing the same |
DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US20040086551A1 (en) * | 2002-10-30 | 2004-05-06 | Miller Kenneth J. | Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl |
ES2239196T3 (es) * | 2002-12-02 | 2005-09-16 | Schwarz Pharma Ag | Suministro iontoforetico de rotigotina para el tratamiento de la enfermedad de parkinson. |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
US20080226698A1 (en) * | 2007-03-16 | 2008-09-18 | Mylan Technologies, Inc. | Amorphous drug transdermal systems, manufacturing methods, and stabilization |
US20080286348A1 (en) * | 2007-05-16 | 2008-11-20 | Todhunter John A | Secured transdermal delivery system |
US9155725B2 (en) * | 2008-02-27 | 2015-10-13 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive skin patch and packaged product |
JP6054013B2 (ja) * | 2008-02-27 | 2016-12-27 | 久光製薬株式会社 | 貼付製剤 |
JP5547065B2 (ja) | 2008-05-15 | 2014-07-09 | 久光製薬株式会社 | パロノセトロンを含有する経皮吸収製剤 |
US8366600B2 (en) * | 2008-06-19 | 2013-02-05 | Nupathe Inc. | Polyamine enhanced formulations for triptan compound iontophoresis |
CN103933018A (zh) * | 2013-01-18 | 2014-07-23 | 江苏康倍得药业有限公司 | 一种透皮给药系统 |
EP3395336A1 (en) * | 2017-04-28 | 2018-10-31 | Nitto Denko Corporation | Transdermal absorption preparation |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0745400B2 (ja) * | 1986-03-29 | 1995-05-17 | 日東電工株式会社 | 外用医薬製剤 |
US4954343A (en) * | 1986-03-29 | 1990-09-04 | Nitto Electric Industrial Co., Ltd. | Dermal pharmaceutical preparations |
DE3743946A1 (de) | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung |
US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
JP2857882B2 (ja) * | 1988-11-02 | 1999-02-17 | 富山化学工業株式会社 | ピロキシカムのプラスター剤 |
DE3933460A1 (de) * | 1989-10-06 | 1991-04-18 | Lohmann Therapie Syst Lts | Oestrogenhaltiges wirkstoffpflaster |
DE3939376C1 (es) * | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
GB9021674D0 (en) * | 1990-10-05 | 1990-11-21 | Ethical Pharma Ltd | Transdermal device |
JPH04261119A (ja) * | 1991-02-13 | 1992-09-17 | Lintec Corp | 経皮吸収型貼付剤 |
CA2077369A1 (en) | 1991-09-09 | 1993-03-10 | Hitoshi Akemi | Acrylic gel material and gel-based medical preparation for percutaneous absorption employing the same |
US5676968A (en) * | 1991-10-31 | 1997-10-14 | Schering Aktiengesellschaft | Transdermal therapeutic systems with crystallization inhibitors |
US5286810A (en) * | 1992-08-07 | 1994-02-15 | Srchem Incorporated | Salt of polymer from maleic acid, polyamind and ammonia |
DE4230588C1 (de) * | 1992-09-12 | 1993-10-07 | Lohmann Therapie Syst Lts | Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung |
DE4238223C1 (de) * | 1992-11-12 | 1994-05-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung |
DE4309830C1 (de) * | 1993-03-26 | 1994-05-05 | Lohmann Therapie Syst Lts | Wirkstoffpflaster für die Abgabe von Estradiol an die Haut |
DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
DE59405277D1 (de) * | 1993-04-20 | 1998-03-26 | Hexal Ag | Wirkstoffplaster |
DE4336557C2 (de) | 1993-05-06 | 1997-07-17 | Lohmann Therapie Syst Lts | Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
DE4333595A1 (de) * | 1993-10-01 | 1995-04-06 | Labtec Gmbh | Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut |
DE4405898A1 (de) * | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
WO1995030409A1 (en) | 1994-05-05 | 1995-11-16 | Merck Frosst Canada Inc. | Topical polymeric drug delivery system |
US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
DE19548332A1 (de) * | 1995-12-22 | 1997-07-10 | Rotta Res Bv | Hormonpflaster |
DE19701949A1 (de) * | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
US5951999A (en) * | 1997-02-21 | 1999-09-14 | Adhesives Research, Inc. | Transdermal pressure sensitive adhesive drug delivery system |
DE19728517C2 (de) * | 1997-07-04 | 1999-11-11 | Sanol Arznei Schwarz Gmbh | TTS zur Verabreichung von Sexualsteroidhormonen und Verfahren zu seiner Herstellung |
-
1998
- 1998-06-25 DE DE19828273A patent/DE19828273B4/de not_active Expired - Fee Related
-
1999
- 1999-06-08 DE DE59901202T patent/DE59901202D1/de not_active Expired - Lifetime
- 1999-06-08 TR TR2000/03839T patent/TR200003839T2/xx unknown
- 1999-06-08 PT PT99927904T patent/PT1089719E/pt unknown
- 1999-06-08 WO PCT/EP1999/003922 patent/WO1999066901A2/de active IP Right Grant
- 1999-06-08 EP EP99927904A patent/EP1089719B1/de not_active Expired - Lifetime
- 1999-06-08 HU HU0102498A patent/HUP0102498A3/hu unknown
- 1999-06-08 JP JP2000555587A patent/JP2002518430A/ja active Pending
- 1999-06-08 ES ES99927904T patent/ES2177290T3/es not_active Expired - Lifetime
- 1999-06-08 KR KR1020007014673A patent/KR100550888B1/ko not_active IP Right Cessation
- 1999-06-08 AT AT99927904T patent/ATE215819T1/de active
- 1999-06-08 CA CA002335582A patent/CA2335582C/en not_active Expired - Fee Related
- 1999-06-08 PL PL345455A patent/PL193080B1/pl not_active IP Right Cessation
- 1999-06-08 US US09/720,287 patent/US6899894B1/en not_active Expired - Fee Related
- 1999-06-08 AU AU45086/99A patent/AU768755B2/en not_active Ceased
- 1999-06-08 NZ NZ509015A patent/NZ509015A/en not_active IP Right Cessation
- 1999-06-08 IL IL14043499A patent/IL140434A0/xx active IP Right Grant
- 1999-06-08 DK DK99927904T patent/DK1089719T3/da active
- 1999-06-08 BR BR9912210-3A patent/BR9912210A/pt not_active Application Discontinuation
- 1999-06-08 CZ CZ20004798A patent/CZ300707B6/cs not_active IP Right Cessation
- 1999-06-08 CN CNB998088706A patent/CN1148172C/zh not_active Expired - Fee Related
- 1999-06-22 TW TW088110455A patent/TW533084B/zh not_active IP Right Cessation
- 1999-06-25 AR ARP990103056A patent/AR019715A1/es active IP Right Grant
-
2000
- 2000-12-20 IL IL140434A patent/IL140434A/en not_active IP Right Cessation
- 2000-12-21 ZA ZA200007751A patent/ZA200007751B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE19828273B4 (de) | 2005-02-24 |
AR019715A1 (es) | 2002-03-13 |
IL140434A0 (en) | 2002-02-10 |
DE19828273A1 (de) | 1999-12-30 |
CN1310616A (zh) | 2001-08-29 |
AU4508699A (en) | 2000-01-10 |
NZ509015A (en) | 2004-01-30 |
WO1999066901A3 (de) | 2000-03-23 |
DK1089719T3 (da) | 2002-08-05 |
DE59901202D1 (de) | 2002-05-16 |
JP2002518430A (ja) | 2002-06-25 |
IL140434A (en) | 2006-10-05 |
CA2335582A1 (en) | 1999-12-29 |
AU768755B2 (en) | 2004-01-08 |
HUP0102498A2 (hu) | 2001-11-28 |
EP1089719A2 (de) | 2001-04-11 |
KR20010053132A (ko) | 2001-06-25 |
CZ20004798A3 (en) | 2001-05-16 |
HUP0102498A3 (en) | 2002-01-28 |
EP1089719B1 (de) | 2002-04-10 |
CA2335582C (en) | 2006-04-11 |
CN1148172C (zh) | 2004-05-05 |
TR200003839T2 (tr) | 2001-06-21 |
CZ300707B6 (cs) | 2009-07-22 |
PL193080B1 (pl) | 2007-01-31 |
ZA200007751B (en) | 2001-07-18 |
TW533084B (en) | 2003-05-21 |
PL345455A1 (en) | 2001-12-17 |
KR100550888B1 (ko) | 2006-02-10 |
ATE215819T1 (de) | 2002-04-15 |
BR9912210A (pt) | 2001-04-10 |
WO1999066901A2 (de) | 1999-12-29 |
PT1089719E (pt) | 2002-09-30 |
US6899894B1 (en) | 2005-05-31 |
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