BRPI0011135B8 - sistema de ministração terapêutica transdérmica contendo agente neuroléptico - Google Patents

sistema de ministração terapêutica transdérmica contendo agente neuroléptico

Info

Publication number
BRPI0011135B8
BRPI0011135B8 BRPI0011135A BR0011135A BRPI0011135B8 BR PI0011135 B8 BRPI0011135 B8 BR PI0011135B8 BR PI0011135 A BRPI0011135 A BR PI0011135A BR 0011135 A BR0011135 A BR 0011135A BR PI0011135 B8 BRPI0011135 B8 BR PI0011135B8
Authority
BR
Brazil
Prior art keywords
delivery system
transdermal therapeutic
therapeutic delivery
system containing
neuroleptic
Prior art date
Application number
BRPI0011135A
Other languages
English (en)
Other versions
BR0011135A (pt
BRPI0011135B1 (pt
Inventor
Horstmann Michael
Bracht Stefan
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of BR0011135A publication Critical patent/BR0011135A/pt
Publication of BRPI0011135B1 publication Critical patent/BRPI0011135B1/pt
Publication of BRPI0011135B8 publication Critical patent/BRPI0011135B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Abstract

"sistema de ministração terapêutica transdérmica, processo para ministrar um neuroléptico altamente potente a um indivíduo, e uso de um sistema de ministração terapêutica transdérmica". a presente invenção se refere a um sistema de ministração terapêutica transdérmica que consiste de uma camada base, pelo menos uma camada matriz contendo substância ativa que pode ao mesmo tempo possuir propriedades de adesivo sensível à pressão, assim como uma camada protetora removível, caracterizada pelo conteúdo de um neuroléptico, o conteúdo de pelo menos um realçante de permeabilidade, assim como por uma camada que é adesiva sensível à pressão no lado de face para a pele e com base em polímeros que são hidrocarbonetos puros.
BRPI0011135A 1999-04-22 2000-04-07 sistema de ministração terapêutica transdérmica contendo agente neuroléptico BRPI0011135B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19918105A DE19918105C1 (de) 1999-04-22 1999-04-22 Transdermales therapeutisches System mit einem stark wirksamen Neuroleptikum
PCT/EP2000/003113 WO2000064419A1 (de) 1999-04-22 2000-04-07 Transdermales therapeutisches system mit einem stark wirksamen neuroleptikum

Publications (3)

Publication Number Publication Date
BR0011135A BR0011135A (pt) 2003-07-29
BRPI0011135B1 BRPI0011135B1 (pt) 2016-09-27
BRPI0011135B8 true BRPI0011135B8 (pt) 2021-05-25

Family

ID=7905367

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0011135A BRPI0011135B8 (pt) 1999-04-22 2000-04-07 sistema de ministração terapêutica transdérmica contendo agente neuroléptico

Country Status (16)

Country Link
US (1) US7560121B1 (pt)
EP (1) EP1171105B1 (pt)
JP (1) JP4163859B2 (pt)
KR (1) KR100610626B1 (pt)
CN (1) CN1194672C (pt)
AR (1) AR025521A1 (pt)
AT (1) ATE270881T1 (pt)
AU (1) AU773905B2 (pt)
BR (1) BRPI0011135B8 (pt)
CA (1) CA2370023C (pt)
DE (2) DE19918105C1 (pt)
ES (1) ES2225126T3 (pt)
MX (1) MXPA01010503A (pt)
TR (1) TR200102915T2 (pt)
WO (1) WO2000064419A1 (pt)
ZA (1) ZA200108512B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027258C1 (de) 2000-05-31 2001-10-31 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit okklusiver wirkstoffhaltiger Schicht und nicht-okklusiver Rückschicht
DE10035891A1 (de) * 2000-07-24 2002-02-14 Lohmann Therapie Syst Lts Medizinischer Haftkleber mit einer zweiphasigen Klebermatrix aus Polyacrylaten und Polyaminsalzen
DE10110953A1 (de) * 2001-03-07 2002-09-19 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Verabreichung von partiellen Dopamin-D2-Agonisten
DE102006054732B4 (de) 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
DE102008034453A1 (de) * 2008-07-24 2010-02-11 Lts Lohmann Therapie-Systeme Ag Verfahren zum Herstellen eines Mehrschichtenverbundes auf einer CIP-fähigen Beschichtungsanlage und Verwendung des damit hergestellten Mehrschichtenverbundes für die transdermale Applikation oder die Applikation in Körperhöhlen
EP2594261A1 (en) * 2011-11-18 2013-05-22 Labtec GmbH Composition for transdermal administration of rivastigmine
WO2016059583A1 (en) * 2014-10-17 2016-04-21 Fidia Farmaceutici S.P.A. Dermal therapeutic system with high adhesivity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE42901T1 (de) * 1984-03-05 1989-05-15 Nitto Denko Corp Haftendes arzneimittelpraeparat fuer perkutane absorption.
JPH01265021A (ja) * 1987-10-29 1989-10-23 Hercon Lab Corp 薬理学的活性物質を含有する組成物を動物組織に制御放出および供給するための物品
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
JP2849937B2 (ja) * 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
US5120545A (en) 1990-08-03 1992-06-09 Alza Corporation Reduction or prevention of sensitization to drugs
US5882676A (en) * 1995-05-26 1999-03-16 Alza Corporation Skin permeation enhancer compositions using acyl lactylates
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
DE69936848T2 (de) * 1998-04-14 2008-05-15 The General Hospital Corp., Boston Verwendung von d-serin oder d-alanin zur behandlung von schizophrenie

Also Published As

Publication number Publication date
AU773905B2 (en) 2004-06-10
CN1194672C (zh) 2005-03-30
TR200102915T2 (tr) 2002-01-21
DE19918105C1 (de) 2000-09-21
ZA200108512B (en) 2002-08-06
ATE270881T1 (de) 2004-07-15
ES2225126T3 (es) 2005-03-16
BR0011135A (pt) 2003-07-29
EP1171105A1 (de) 2002-01-16
AR025521A1 (es) 2002-12-04
EP1171105B1 (de) 2004-07-14
BRPI0011135B1 (pt) 2016-09-27
AU4398600A (en) 2000-11-10
US7560121B1 (en) 2009-07-14
CA2370023C (en) 2009-06-23
DE50007077D1 (de) 2004-08-19
MXPA01010503A (es) 2002-05-14
JP2002542278A (ja) 2002-12-10
CA2370023A1 (en) 2000-11-02
JP4163859B2 (ja) 2008-10-08
KR20010112453A (ko) 2001-12-20
WO2000064419A1 (de) 2000-11-02
KR100610626B1 (ko) 2006-08-09
CN1348366A (zh) 2002-05-08

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/09/2016, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

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