ES2098398T3 - Procedimiento para la produccion fermentativa de aminoacidos. - Google Patents
Procedimiento para la produccion fermentativa de aminoacidos.Info
- Publication number
- ES2098398T3 ES2098398T3 ES92112903T ES92112903T ES2098398T3 ES 2098398 T3 ES2098398 T3 ES 2098398T3 ES 92112903 T ES92112903 T ES 92112903T ES 92112903 T ES92112903 T ES 92112903T ES 2098398 T3 ES2098398 T3 ES 2098398T3
- Authority
- ES
- Spain
- Prior art keywords
- amino acids
- fermentative production
- procedure
- branch
- amisticide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 4
- 238000012262 fermentative production Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000186146 Brevibacterium Species 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000186216 Corynebacterium Species 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4130867A DE4130867A1 (de) | 1991-09-17 | 1991-09-17 | Verfahren zur fermentativen herstellung von aminosaeuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2098398T3 true ES2098398T3 (es) | 1997-05-01 |
Family
ID=6440783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92112903T Expired - Lifetime ES2098398T3 (es) | 1991-09-17 | 1992-07-29 | Procedimiento para la produccion fermentativa de aminoacidos. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5770409A (OSRAM) |
| EP (1) | EP0532867B1 (OSRAM) |
| JP (1) | JP2965799B2 (OSRAM) |
| KR (1) | KR100254023B1 (OSRAM) |
| CN (1) | CN1038693C (OSRAM) |
| AT (1) | ATE149571T1 (OSRAM) |
| AU (1) | AU656416B2 (OSRAM) |
| BR (1) | BR9203587A (OSRAM) |
| CA (1) | CA2078364C (OSRAM) |
| CZ (1) | CZ263392A3 (OSRAM) |
| DE (2) | DE4130867A1 (OSRAM) |
| DK (1) | DK0532867T3 (OSRAM) |
| ES (1) | ES2098398T3 (OSRAM) |
| FI (1) | FI104836B (OSRAM) |
| GR (1) | GR3023364T3 (OSRAM) |
| MX (1) | MX9205248A (OSRAM) |
| RU (1) | RU2107097C1 (OSRAM) |
| SK (1) | SK279888B6 (OSRAM) |
| TW (1) | TW206984B (OSRAM) |
| UA (1) | UA27034C2 (OSRAM) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19547361A1 (de) * | 1995-12-19 | 1997-06-26 | Degussa | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation |
| CA2255130A1 (en) | 1997-12-16 | 1999-06-16 | Archer Daniels Midland Company | Process for making granular l-lysine feed supplement |
| RU2187942C2 (ru) * | 1998-06-17 | 2002-08-27 | Арчер Дэниелс Мидленд Компани | Способ получения гранулированной кормовой добавки l-лизина (варианты) |
| CN1236690C (zh) * | 1999-06-23 | 2006-01-18 | 德古萨股份公司 | 含有赖氨酸的含水动物饲料添加剂及其生产方法 |
| DE10021828A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das cdsA-Gen kodierende Nukleotidsequenzen |
| DE10021832A1 (de) * | 2000-05-04 | 2001-11-08 | Degussa | Neue für das cma-Gen kodierende Nukleotidsequenzen |
| JP4362959B2 (ja) * | 2000-08-24 | 2009-11-11 | 味の素株式会社 | 塩基性アミノ酸の製造方法 |
| JP2002284749A (ja) | 2001-03-23 | 2002-10-03 | Ajinomoto Co Inc | 塩基性アミノ酸溶液の製造方法 |
| US7718361B2 (en) | 2002-12-06 | 2010-05-18 | Roche Molecular Systems, Inc. | Quantitative test for bacterial pathogens |
| US20040115304A1 (en) * | 2002-12-16 | 2004-06-17 | Frank Dubner | Feesdstuffs additives containing L-lysine with improved abrasion resistance, and process for their production |
| WO2005021772A1 (en) * | 2003-08-29 | 2005-03-10 | Degussa Ag | Process for the preparation of l-lysine |
| WO2005021771A2 (en) * | 2003-08-29 | 2005-03-10 | Degussa Ag | Process for the production of l-lysine |
| WO2005021773A1 (en) * | 2003-08-29 | 2005-03-10 | Degussa Ag | Process for the preparation of l-lysine |
| DE102004026152A1 (de) | 2004-05-28 | 2005-12-15 | Basf Ag | Fermentative Herstellung von Feinchemikalien |
| CN103088080B (zh) | 2004-10-07 | 2016-02-17 | 味之素株式会社 | 生产碱性物质的方法 |
| DE102005032429A1 (de) | 2005-01-19 | 2006-07-20 | Degussa Ag | Allele des mqo-Gens aus coryneformen Bakterien |
| CN100371437C (zh) * | 2005-02-01 | 2008-02-27 | 湛江海洋大学 | 生产复合氨基酸的地衣芽孢杆菌菌株及养殖用氨基酸液肥制备方法 |
| DE102005013676A1 (de) | 2005-03-24 | 2006-09-28 | Degussa Ag | Allele des zwf-Gens aus coryneformen Bakterien |
| DE102005023829A1 (de) | 2005-05-24 | 2006-11-30 | Degussa Ag | Allele des opcA-Gens aus coryneformen Bakterien |
| US20070082031A1 (en) * | 2005-10-08 | 2007-04-12 | Hermann Lotter | L-lysine-containing feed additives |
| DE102005056668A1 (de) | 2005-11-28 | 2007-05-31 | Basf Ag | Fermentative Herstellung organischer Verbindungen |
| DE102006032634A1 (de) | 2006-07-13 | 2008-01-17 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren |
| DE102007019643A1 (de) | 2007-04-26 | 2008-10-30 | Evonik Degussa Gmbh | Verfahren zur Herstellung von zuckerhaltigen Hydrolysaten aus Lignocellulose |
| DE102009030342A1 (de) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen |
| EP2479279A1 (de) | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren |
| DE102011006716A1 (de) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
| DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
| RU2486248C2 (ru) * | 2011-06-29 | 2013-06-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет инженерной экологии" (ФГБОУ ВПО "МГУИЭ") | Способ биосинтеза l-лизина |
| EP2628792A1 (de) | 2012-02-17 | 2013-08-21 | Evonik Industries AG | Zelle mit verringerter ppGppase-Aktivität |
| BR112014021439B1 (pt) | 2012-04-27 | 2021-12-21 | Evonik Technochemie Gmbh | Polipeptídeo de isopropilmalato sintase e a sequência de nucleotídeos que o codifica, vetor, microrganismo do gênero corynebacterium e uso do mesmo, bem como processo fermentativo para a produção de kic ou l-leucina |
| PE20142304A1 (es) | 2012-05-09 | 2015-01-10 | Evonik Industries Ag | Aditivo para piensos que contienen l-aminoacido en forma de un material granular a base de caldo de fermentacion y metodo para produccion |
| PL2700715T3 (pl) | 2012-08-20 | 2019-03-29 | Evonik Degussa Gmbh | Sposób fermentacyjnego wytwarzania L-aminokwasów z zastosowaniem ulepszonych szczepów z rodziny Enterobacteriaceae |
| DE102012024435A1 (de) | 2012-12-14 | 2014-07-10 | Forschungszentrum Jülich GmbH | Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren |
| EP2762571A1 (de) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren |
| PL2811028T3 (pl) | 2013-06-03 | 2017-07-31 | Evonik Degussa Gmbh | Sposób wytwarzania L-waliny z zastosowaniem zrekombinowanych bakterii maczugowatych zawierających operon ilvBN indukowany propionianem |
| EP2865274B1 (de) | 2013-10-24 | 2020-03-04 | Evonik Operations GmbH | L-Aminosäure enthaltendes Futtermitteladditiv |
| DK2865275T3 (da) | 2013-10-24 | 2020-05-18 | Evonik Operations Gmbh | Foderstofadditiv indeholdende L-aminosyre |
| EP2940039A1 (de) | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems |
| EP2940144A1 (de) | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums |
| PL2940143T3 (pl) | 2014-04-30 | 2020-06-29 | Evonik Operations Gmbh | Sposób wytwarzania L-aminokwasów z użyciem bakterii bazofilowych |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| KR20180084756A (ko) | 2015-12-07 | 2018-07-25 | 지머젠 인코포레이티드 | 코리네박테리움 글루타미컴으로부터의 프로모터 |
| JP2019062742A (ja) | 2016-02-24 | 2019-04-25 | 味の素株式会社 | L−アミノ酸の製造法 |
| US10544411B2 (en) | 2016-06-30 | 2020-01-28 | Zymergen Inc. | Methods for generating a glucose permease library and uses thereof |
| KR102345899B1 (ko) | 2016-06-30 | 2021-12-31 | 지머젠 인코포레이티드 | 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도 |
| CN111601897A (zh) | 2016-12-30 | 2020-08-28 | 奎多公司 | 用于确定细菌对抗生素或益菌剂的易感性的噬菌体介导的免疫分析和方法 |
| CN110869504A (zh) | 2017-06-07 | 2020-03-06 | 齐默尔根公司 | 来自谷氨酸棒状杆菌的启动子及其在调节辅助基因表达中的用途 |
| EP3415622A1 (en) | 2017-06-14 | 2018-12-19 | Evonik Degussa GmbH | Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases |
| CN108018325B (zh) * | 2017-08-23 | 2020-10-09 | 江南大学 | 提高谷胱甘肽产量的方法 |
| EP3456833A1 (en) | 2017-09-18 | 2019-03-20 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
| CN111788314A (zh) | 2017-10-02 | 2020-10-16 | 奎多公司 | 用于抗微生物剂敏感性测试和细菌菌种确认的基于噬菌体的检测方法 |
| EP3467099A1 (en) | 2017-10-05 | 2019-04-10 | Evonik Degussa GmbH | Method for the fermentative production of l-amino acids |
| EP3498853A1 (en) | 2017-12-14 | 2019-06-19 | Evonik Degussa GmbH | Method for the fermentative production of l-lysine |
| EP3594355A1 (en) | 2018-07-12 | 2020-01-15 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| EP3599282B1 (en) | 2018-07-24 | 2021-03-17 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| RU2019128538A (ru) | 2018-09-26 | 2021-03-11 | Эвоник Оперейшенс ГмбХ | Способ ферментативного получения l-лизина |
| EP3660158A1 (en) | 2018-11-29 | 2020-06-03 | Evonik Operations GmbH | Method for the fermentative production of l-lysine |
| WO2022013287A1 (en) | 2020-07-15 | 2022-01-20 | Evonik Operations Gmbh | Polynucleotide encoding an amino acid sequence, encoding an oxidoreductase |
| CN117813315A (zh) | 2021-08-09 | 2024-04-02 | 赢创运营有限公司 | 用于生产重组细菌胶原样蛋白(clp)的方法 |
| WO2023016890A1 (en) | 2021-08-09 | 2023-02-16 | Evonik Operations Gmbh | Method for producing a recombinant bacterial collagen-like protein (clp) |
| CN117957242A (zh) | 2021-08-09 | 2024-04-30 | 赢创运营有限公司 | 编码细菌胶原样蛋白的多核苷酸 |
| WO2023041425A1 (en) | 2021-09-20 | 2023-03-23 | Evonik Operations Gmbh | Method for the fermentative production of l-lysine using c. glutamicum strains expressing modified gluconate repressor proteins gntr1 and gntr2 |
| WO2023041689A1 (en) | 2021-09-20 | 2023-03-23 | Evonik Operations Gmbh | Non-adhesive collagen-like hydrogels |
| KR102737643B1 (ko) | 2021-10-19 | 2024-12-04 | 씨제이제일제당 주식회사 | 아미노산 발효 공정에서 발생한 고농도 발효 부산물의 처리방법 |
| US20250195715A1 (en) | 2022-02-25 | 2025-06-19 | Evonik Operations Gmbh | Sponges based on collagen-like proteins |
| EP4486759A1 (en) | 2022-03-01 | 2025-01-08 | Evonik Operations GmbH | Biotechnological production of collagen proteins and bacterial collagen-like proteins by recombinant microorganisms |
| CN121263216A (zh) | 2023-06-06 | 2026-01-02 | 赢创运营有限公司 | 由胶原样蛋白(clp)制备的水凝胶贴剂 |
| WO2025016819A1 (en) | 2023-07-20 | 2025-01-23 | Evonik Operations Gmbh | Sponge comprising a recombinant collagen-like peptide (clp) and bioactive glass |
| EP4497818A1 (en) | 2023-07-25 | 2025-01-29 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains expressing heterologous nicotinamide nucleotide transhydrogenase pntab |
| WO2025186007A1 (en) | 2024-03-08 | 2025-09-12 | Evonik Operations Gmbh | Collagen-like protein coated medical devices and coating method thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE269167C (OSRAM) * | ||||
| FR2488273A1 (fr) * | 1980-08-07 | 1982-02-12 | Inst Mikrobiologii Im Avg | Procede microbiologique de preparation de l-lysine et l-lysine obtenue par ledit procede |
| JPS57115186A (en) * | 1980-12-29 | 1982-07-17 | Ajinomoto Co Inc | Preparation of l-lysine by fermentation |
| SU1157059A1 (ru) * | 1983-02-28 | 1985-05-23 | Белорусский Ордена Трудового Красного Знамени Технологический Институт Им.С.М.Кирова | Способ получени @ -лизина |
| DD268834A3 (de) * | 1983-06-03 | 1989-06-14 | Ve Forschungszentrum Biotechno | Verfahren zur fermentativen herstellung von l-lysin |
| FR2604447B1 (fr) * | 1986-09-29 | 1989-05-19 | Ajinomoto Kk | Procede de production de l-threonine par fermentation |
| DD269167A1 (de) * | 1987-07-30 | 1989-06-21 | Ve Forschungszentrum Biotechno | Verfahren zur mikrobiologischen herstellung von l-lysin |
| KR910002850B1 (ko) * | 1989-03-30 | 1991-05-06 | 제일제당 주식회사 | L-라이신을 생산하는 미생물 및 이를 이용한 l-라이신의 제조방법 |
| AU5600590A (en) * | 1989-06-01 | 1990-12-06 | Unisearch Limited | High lysine producing microorganisms |
-
1991
- 1991-09-17 DE DE4130867A patent/DE4130867A1/de not_active Withdrawn
-
1992
- 1992-07-29 AT AT92112903T patent/ATE149571T1/de active
- 1992-07-29 DK DK92112903.7T patent/DK0532867T3/da active
- 1992-07-29 ES ES92112903T patent/ES2098398T3/es not_active Expired - Lifetime
- 1992-07-29 DE DE59208102T patent/DE59208102D1/de not_active Expired - Lifetime
- 1992-07-29 EP EP92112903A patent/EP0532867B1/de not_active Expired - Lifetime
- 1992-08-26 CZ CS922633A patent/CZ263392A3/cs unknown
- 1992-08-26 SK SK2633-92A patent/SK279888B6/sk not_active IP Right Cessation
- 1992-09-15 BR BR929203587A patent/BR9203587A/pt not_active Application Discontinuation
- 1992-09-15 MX MX9205248A patent/MX9205248A/es unknown
- 1992-09-16 AU AU24559/92A patent/AU656416B2/en not_active Ceased
- 1992-09-16 CA CA002078364A patent/CA2078364C/en not_active Expired - Fee Related
- 1992-09-16 RU SU5052640A patent/RU2107097C1/ru not_active IP Right Cessation
- 1992-09-16 FI FI924146A patent/FI104836B/fi not_active IP Right Cessation
- 1992-09-16 CN CN92110718A patent/CN1038693C/zh not_active Expired - Lifetime
- 1992-09-17 KR KR1019920016885A patent/KR100254023B1/ko not_active Expired - Lifetime
- 1992-09-17 JP JP4247942A patent/JP2965799B2/ja not_active Expired - Lifetime
- 1992-10-13 TW TW081108136A patent/TW206984B/zh not_active IP Right Cessation
-
1993
- 1993-06-10 UA UA93002075A patent/UA27034C2/uk unknown
-
1996
- 1996-07-10 US US08/677,911 patent/US5770409A/en not_active Expired - Lifetime
-
1997
- 1997-05-09 GR GR970401016T patent/GR3023364T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU656416B2 (en) | 1995-02-02 |
| JPH05244969A (ja) | 1993-09-24 |
| FI924146A0 (fi) | 1992-09-16 |
| EP0532867A1 (de) | 1993-03-24 |
| FI104836B (fi) | 2000-04-14 |
| DE59208102D1 (de) | 1997-04-10 |
| KR100254023B1 (ko) | 2000-04-15 |
| MX9205248A (es) | 1993-05-01 |
| DE4130867A1 (de) | 1993-03-18 |
| KR930006157A (ko) | 1993-04-20 |
| US5770409A (en) | 1998-06-23 |
| EP0532867B1 (de) | 1997-03-05 |
| GR3023364T3 (en) | 1997-08-29 |
| CA2078364A1 (en) | 1993-03-18 |
| ATE149571T1 (de) | 1997-03-15 |
| CA2078364C (en) | 2003-05-06 |
| CN1070687A (zh) | 1993-04-07 |
| CZ263392A3 (en) | 1993-04-14 |
| TW206984B (OSRAM) | 1993-06-01 |
| JP2965799B2 (ja) | 1999-10-18 |
| SK263392A3 (en) | 1996-01-10 |
| SK279888B6 (sk) | 1999-05-07 |
| CN1038693C (zh) | 1998-06-10 |
| AU2455992A (en) | 1993-03-18 |
| RU2107097C1 (ru) | 1998-03-20 |
| BR9203587A (pt) | 1993-04-13 |
| FI924146L (fi) | 1993-03-18 |
| DK0532867T3 (da) | 1997-07-28 |
| UA27034C2 (uk) | 2000-02-28 |
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