EG20333A - Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances - Google Patents

Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances

Info

Publication number
EG20333A
EG20333A EG1193A EG1193A EG20333A EG 20333 A EG20333 A EG 20333A EG 1193 A EG1193 A EG 1193A EG 1193 A EG1193 A EG 1193A EG 20333 A EG20333 A EG 20333A
Authority
EG
Egypt
Prior art keywords
pharmaceutical agent
urinary tract
benzothiopyran derivatives
tract disturbances
benzopyran
Prior art date
Application number
EG1193A
Other languages
English (en)
Inventor
Amedeo Leonardi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI920408A external-priority patent/IT1254469B/it
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of EG20333A publication Critical patent/EG20333A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/322,3-Dihydro derivatives, e.g. flavanones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
EG1193A 1992-02-25 1993-02-25 Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances EG20333A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI920408A IT1254469B (it) 1992-02-25 1992-02-25 Derivati benzopiranici e benzotiopiranici
US07/888,775 US5403842A (en) 1992-02-25 1992-05-26 Benzopyran and benzothiopyran derivatives

Publications (1)

Publication Number Publication Date
EG20333A true EG20333A (en) 1998-10-31

Family

ID=26330842

Family Applications (1)

Application Number Title Priority Date Filing Date
EG1193A EG20333A (en) 1992-02-25 1993-02-25 Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances

Country Status (25)

Country Link
EP (1) EP0558245A1 (hu)
JP (1) JPH069606A (hu)
AU (2) AU3629693A (hu)
BG (1) BG61946B1 (hu)
CA (1) CA2090156A1 (hu)
CZ (1) CZ205994A3 (hu)
DZ (1) DZ1666A1 (hu)
EE (1) EE03177B1 (hu)
EG (1) EG20333A (hu)
FI (1) FI943876A0 (hu)
HR (1) HRP930210A2 (hu)
HU (1) HUT72448A (hu)
IL (1) IL104824A (hu)
LT (1) LT3038B (hu)
LV (1) LV10099B (hu)
MX (1) MX9300977A (hu)
NO (1) NO943140D0 (hu)
NZ (1) NZ245995A (hu)
PL (1) PL175556B1 (hu)
SG (1) SG65570A1 (hu)
SI (1) SI9300094A (hu)
SK (1) SK280143B6 (hu)
TW (1) TW382628B (hu)
WO (1) WO1993017007A1 (hu)
ZA (1) ZA931278B (hu)

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FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
GB9317071D0 (en) * 1993-08-17 1993-09-29 Univ Strathclyde Flavonoids
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FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
ES2101620B1 (es) * 1994-03-18 1998-04-01 Ferrer Int Nuevo compuesto derivado del cromeno.
IL112764A0 (en) * 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives
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US5503843A (en) * 1994-04-22 1996-04-02 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
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US5859014A (en) * 1995-06-09 1999-01-12 Syntex (U.S.A.) Inc. Pyrimidinedione, pyrimidinetrione, triazinedione and tetrahydroquinazolinedione derivatives as α1 -adrenergic receptor antagonists
ATE201016T1 (de) * 1995-06-09 2001-05-15 Hoffmann La Roche Pyrimidindion-, pyrimidintrion-, triazindion- derivate als alpha-1-adrenergische rezeptorantagonisten
JPH0967367A (ja) 1995-06-23 1997-03-11 Suntory Ltd チオピラン誘導体
WO1997014419A1 (en) * 1995-10-20 1997-04-24 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
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FR2745815B1 (fr) * 1996-03-08 1998-06-26 Synthelabo Derives de benzofurane, leur preparations et compositions pharmaceutiques les comprenant
JP2000506157A (ja) * 1996-03-08 2000-05-23 サンテラボ (2―アミノエチル)ベンゾフラン誘導体、その製造およびその治療的使用
KR20000068255A (ko) * 1996-08-22 2000-11-25 게리 디. 스트리트, 스티븐 엘. 네스비트 선택성 도파민 d4 수용체 리간드로서의 트로포닐 피페라진
AU2002300904B2 (en) * 1997-05-12 2004-12-23 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
DE69818255T2 (de) * 1997-05-12 2004-12-23 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituierte piperazine die bei der behandlung von gutartiger prostatischer hyperlasie nützlich sind
DE69818079T2 (de) 1997-06-04 2004-06-03 Azwell Inc. Verfahren zur herstellung von piperazinsulfonamid-derivaten und ihren salzen
WO1999003833A1 (en) * 1997-07-15 1999-01-28 Sankyo Company, Limited Piperazine derivatives
US6306861B1 (en) 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
US6387909B1 (en) 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
IT1313581B1 (it) * 1999-07-30 2002-09-09 Recordati Chem Pharm Derivati tienopirancarbossamidici.
DE19941657A1 (de) * 1999-09-01 2001-03-08 Schwabe Willmar Gmbh & Co Zimtsäurenitrile, Verfahren zu ihrer Herstellung und Verwendung
IT1314192B1 (it) * 1999-10-18 2002-12-06 Recordati Chem Pharm Derivati benzopiranici
US6403594B1 (en) 1999-10-18 2002-06-11 Recordati, S.A. Chemical And Pharmaceutical Company Benzopyran derivatives
JP2002113006A (ja) 2000-10-10 2002-04-16 Toshiba Medical System Co Ltd 診断機器設定方法および診断装置
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JP5611957B2 (ja) * 2008-09-29 2014-10-22 サートリス ファーマシューティカルズ, インコーポレイテッド サーチュインモジュレーターとしてのキナゾリノン、キノロンおよび関連するアナログ
CZ304045B6 (cs) 2012-04-10 2013-09-04 Univerzita Palackého Pouzití komplexu medi obsahujících 2-fenyl-3-hydroxychinolin-4(1H)-on a deriváty 1,10-fenanthrolinu pro prípravu léciv pro lécbu nádorových onemocnení
ES2880766T3 (es) 2016-02-09 2021-11-25 Pharmakea Inc Inhibidores de quinolinona lisil oxidasa similar al tipo 2 y usos de los mismos
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CA3160428A1 (en) * 2019-11-11 2021-05-20 Southwest Research Institute Recrystallized hi-6 dimethylsulfate
PE20230300A1 (es) 2019-12-06 2023-02-13 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio
IL308953A (en) 2021-06-04 2024-01-01 Vertex Pharma N-Hydroalkyl(Hetero)Aryl)Tetrahydrofuran Carboxamides as Natrene Channel Modulators
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Also Published As

Publication number Publication date
TW382628B (en) 2000-02-21
AU3629693A (en) 1993-09-13
BG98990A (bg) 1995-05-31
WO1993017007A1 (en) 1993-09-02
EP0558245A1 (en) 1993-09-01
FI943876A (fi) 1994-08-23
SK280143B6 (sk) 1999-09-10
IL104824A (en) 1999-12-22
JPH069606A (ja) 1994-01-18
SK100794A3 (en) 1995-04-12
LTIP354A (lt) 1994-04-25
AU3377393A (en) 1993-08-26
IL104824A0 (en) 1993-06-10
LV10099A (lv) 1994-05-10
AU660067B2 (en) 1995-06-08
MX9300977A (es) 1993-12-01
PL175556B1 (pl) 1999-01-29
LT3038B (en) 1994-09-25
NO943140L (no) 1994-08-25
BG61946B1 (bg) 1998-10-30
ZA931278B (en) 1993-11-18
SI9300094A (en) 1993-09-30
NO943140D0 (no) 1994-08-25
HU9402443D0 (en) 1994-10-28
EE03177B1 (et) 1999-04-15
SG65570A1 (en) 1999-06-22
CZ205994A3 (en) 1995-02-15
NZ245995A (en) 1994-09-27
HRP930210A2 (en) 1995-06-30
FI943876A0 (fi) 1994-08-23
HUT72448A (en) 1996-04-29
CA2090156A1 (en) 1993-08-26
DZ1666A1 (fr) 2002-02-17
LV10099B (en) 1995-02-20

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