EG20333A - Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances - Google Patents

Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances

Info

Publication number
EG20333A
EG20333A EG1193A EG1193A EG20333A EG 20333 A EG20333 A EG 20333A EG 1193 A EG1193 A EG 1193A EG 1193 A EG1193 A EG 1193A EG 20333 A EG20333 A EG 20333A
Authority
EG
Egypt
Prior art keywords
pharmaceutical agent
urinary tract
benzothiopyran derivatives
tract disturbances
benzopyran
Prior art date
Application number
EG1193A
Inventor
Amedeo Leonardi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI920408A external-priority patent/IT1254469B/en
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of EG20333A publication Critical patent/EG20333A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
EG1193A 1992-02-25 1993-02-25 Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances EG20333A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI920408A IT1254469B (en) 1992-02-25 1992-02-25 BENZOPYRANIC AND BENZOTHIOPYRANIC DERIVATIVES
US07/888,775 US5403842A (en) 1992-02-25 1992-05-26 Benzopyran and benzothiopyran derivatives

Publications (1)

Publication Number Publication Date
EG20333A true EG20333A (en) 1998-10-31

Family

ID=26330842

Family Applications (1)

Application Number Title Priority Date Filing Date
EG1193A EG20333A (en) 1992-02-25 1993-02-25 Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances

Country Status (25)

Country Link
EP (1) EP0558245A1 (en)
JP (1) JPH069606A (en)
AU (2) AU3629693A (en)
BG (1) BG61946B1 (en)
CA (1) CA2090156A1 (en)
CZ (1) CZ205994A3 (en)
DZ (1) DZ1666A1 (en)
EE (1) EE03177B1 (en)
EG (1) EG20333A (en)
FI (1) FI943876A0 (en)
HR (1) HRP930210A2 (en)
HU (1) HUT72448A (en)
IL (1) IL104824A (en)
LT (1) LT3038B (en)
LV (1) LV10099B (en)
MX (1) MX9300977A (en)
NO (1) NO943140L (en)
NZ (1) NZ245995A (en)
PL (1) PL175556B1 (en)
SG (1) SG65570A1 (en)
SI (1) SI9300094A (en)
SK (1) SK280143B6 (en)
TW (1) TW382628B (en)
WO (1) WO1993017007A1 (en)
ZA (1) ZA931278B (en)

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IL112764A0 (en) * 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives
ES2101620B1 (en) * 1994-03-18 1998-04-01 Ferrer Int NEW COMPOUND DERIVED FROM CHROMENE.
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EP0748800B1 (en) * 1995-06-09 2001-05-09 F. Hoffmann-La Roche Ag Pyrimidinedione, pyrimidinetrione, triazinedione derivatives as alpha-1-adrenergic receptor antagonists
US5859014A (en) * 1995-06-09 1999-01-12 Syntex (U.S.A.) Inc. Pyrimidinedione, pyrimidinetrione, triazinedione and tetrahydroquinazolinedione derivatives as α1 -adrenergic receptor antagonists
JPH0967367A (en) * 1995-06-23 1997-03-11 Suntory Ltd Thiopyran derivative
WO1997014419A1 (en) * 1995-10-20 1997-04-24 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
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IT1282705B1 (en) * 1996-02-28 1998-03-31 Recordati Chem Pharm USE OF 5-HT | A SEROTONINERGIC RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE
JP2000506157A (en) * 1996-03-08 2000-05-23 サンテラボ (2-Aminoethyl) benzofuran derivatives, their production and their therapeutic use
FR2745815B1 (en) * 1996-03-08 1998-06-26 Synthelabo BENZOFURANE DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
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EA001904B1 (en) 1997-05-12 2001-10-22 ОРТО МакНЕЙЛ ФАРМАСЬЮТИКАЛ, ИНК. Arylsubstituted piperazines useful in the treatment of bening prostatic hyperplasia
AU2002300904B2 (en) * 1997-05-12 2004-12-23 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
EP1020443B1 (en) 1997-06-04 2003-09-10 Azwell Inc. Process for producing piperazinesulfonamide derivatives and salts thereof
AU8130298A (en) * 1997-07-15 1999-02-10 Sankyo Company Limited Piperazine derivatives
US6306861B1 (en) 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
IT1313581B1 (en) * 1999-07-30 2002-09-09 Recordati Chem Pharm TIENOPIRANCARBOSSAMIDICI DERIVATIVES.
US6387909B1 (en) 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
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JP2008507518A (en) 2004-07-22 2008-03-13 ピーティーシー セラピューティクス，インコーポレーテッド Thienopyridine for treating hepatitis C
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MX2011003373A (en) * 2008-09-29 2011-06-09 Sirtris Pharmaceuticals Inc Quinazolinone, quinolone and related analogs as sirtuin modulators.
CZ2012242A3 (en) 2012-04-10 2013-09-04 Univerzita Palackého Use of copper complexes containing 2-phenyl-3-hydroquinolin-4(1H)-one and derivatives of 1,10-fenanthrolin for preparing medicaments intended for treating tumor diseases
ES2880766T3 (en) 2016-02-09 2021-11-25 Pharmakea Inc Quinolinone lysyl oxidase inhibitors similar to type 2 and uses thereof
TW202031644A (en) * 2018-11-06 2020-09-01 日商第一三共股份有限公司 Benzimidazole derivative
US20210138359A1 (en) * 2019-11-11 2021-05-13 Southwest Research Institute Recrystallized HI-6 Dimethylsulfate
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Also Published As

Publication number Publication date
IL104824A (en) 1999-12-22
LTIP354A (en) 1994-04-25
NO943140D0 (en) 1994-08-25
LV10099A (en) 1994-05-10
AU660067B2 (en) 1995-06-08
FI943876A (en) 1994-08-23
LT3038B (en) 1994-09-25
MX9300977A (en) 1993-12-01
EP0558245A1 (en) 1993-09-01
IL104824A0 (en) 1993-06-10
SK100794A3 (en) 1995-04-12
HU9402443D0 (en) 1994-10-28
SI9300094A (en) 1993-09-30
NO943140L (en) 1994-08-25
FI943876A0 (en) 1994-08-23
NZ245995A (en) 1994-09-27
AU3377393A (en) 1993-08-26
WO1993017007A1 (en) 1993-09-02
ZA931278B (en) 1993-11-18
SK280143B6 (en) 1999-09-10
EE03177B1 (en) 1999-04-15
BG98990A (en) 1995-05-31
TW382628B (en) 2000-02-21
AU3629693A (en) 1993-09-13
PL175556B1 (en) 1999-01-29
BG61946B1 (en) 1998-10-30
HUT72448A (en) 1996-04-29
SG65570A1 (en) 1999-06-22
HRP930210A2 (en) 1995-06-30
CZ205994A3 (en) 1995-02-15
CA2090156A1 (en) 1993-08-26
LV10099B (en) 1995-02-20
DZ1666A1 (en) 2002-02-17
JPH069606A (en) 1994-01-18

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