IT1254469B - Derivati benzopiranici e benzotiopiranici - Google Patents
Derivati benzopiranici e benzotiopiraniciInfo
- Publication number
- IT1254469B IT1254469B ITMI920408A ITMI920408A IT1254469B IT 1254469 B IT1254469 B IT 1254469B IT MI920408 A ITMI920408 A IT MI920408A IT MI920408 A ITMI920408 A IT MI920408A IT 1254469 B IT1254469 B IT 1254469B
- Authority
- IT
- Italy
- Prior art keywords
- compounds
- benzothiopyranic
- benzopyranic
- derivatives
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Abstract
Vengono descritti nuovi derivati benzopiranici e benzotiopiranici dotati di elevata affinità per i recettori ?-adrenergici e serotoninergici 5HT1A. Tali composti possono essere utili agenti terapeutici per il trattamento delle patologie legate a detti sistemi recettoriali. A differenza degli ?-antagonisti noti, tali composti hanno scarsa attività sulla pressione e sono di bassa tossicità. Possono quindi risultare particolarmente utili come agenti terapeutici per il trattamento dei disturbi della minzione associati a disfunzioni ostruttive del basso tratto urinario, quali l'ipertrofia prostatica benigna, nonché per altre malattie di questo distretto. Vengono anche descritti i procedimenti per ottenere detti composti.
Priority Applications (33)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI920408A IT1254469B (it) | 1992-02-25 | 1992-02-25 | Derivati benzopiranici e benzotiopiranici |
US07/888,775 US5403842A (en) | 1992-02-25 | 1992-05-26 | Benzopyran and benzothiopyran derivatives |
SG1996004802A SG65570A1 (en) | 1992-02-25 | 1993-02-22 | Heterobicyclic compounds |
HR930210A HRP930210A2 (en) | 1992-02-25 | 1993-02-22 | Heterobicyclic compounds and pharmaceutical preparations containing them |
EP93301264A EP0558245A1 (en) | 1992-02-25 | 1993-02-22 | Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors |
MX9300977A MX9300977A (es) | 1992-02-25 | 1993-02-23 | Compuetos heterobiciclicos. |
AU36296/93A AU3629693A (en) | 1992-02-25 | 1993-02-23 | Heterobicyclic compounds |
IL10482493A IL104824A (en) | 1992-02-25 | 1993-02-23 | Heterobicyclic compounds and pharmaceutical compositions containing them |
PCT/EP1993/000420 WO1993017007A1 (en) | 1992-02-25 | 1993-02-23 | Heterobicyclic compounds |
HU9402443A HUT72448A (en) | 1992-02-25 | 1993-02-23 | O-, n- ors-containing heterobicyclic compounds, pharmaceutical compositions comprising them and process for their preparation |
CA002090156A CA2090156A1 (en) | 1992-02-25 | 1993-02-23 | Heterobicyclic compounds |
SK1007-94A SK280143B6 (sk) | 1992-02-25 | 1993-02-23 | Heterobicyklické zlúčeniny, spôsoby ich prípravy a |
RO94-01404A RO112111B1 (ro) | 1992-02-25 | 1993-02-23 | Compuşi heterobiciclici, procedee pentru prepararea acestora şi compoziţii farmaceutice care îi conţin |
RU94043324A RU2128656C1 (ru) | 1992-02-25 | 1993-02-23 | Гетеробициклическое соединение, фармацевтическая композиция, способы получения гетеробициклического соединения |
PL93304889A PL175556B1 (pl) | 1992-02-25 | 1993-02-23 | Pochodne benzopiranu, benzotiopiranu i benzofuranu oraz sposób ich wytwarzania |
CZ942059A CZ205994A3 (en) | 1992-02-25 | 1993-02-23 | Heterobicyclic compounds |
AU33773/93A AU660067B2 (en) | 1992-02-25 | 1993-02-24 | Benzopyranone derivatives and analogues |
ZA931278A ZA931278B (en) | 1992-02-25 | 1993-02-24 | Heterobicyclic compounds |
LTIP354A LT3038B (en) | 1992-02-25 | 1993-02-24 | Heterobicyclic compounds |
LVP-93-136A LV10099B (en) | 1992-02-25 | 1993-02-24 | Bicyclic heterocyclic compounds |
DZ930019A DZ1666A1 (fr) | 1992-02-25 | 1993-02-24 | Composés hétérobicycliques. |
JP5036605A JPH069606A (ja) | 1992-02-25 | 1993-02-25 | ヘテロビサイクリック化合物 |
SI19939300094A SI9300094A (en) | 1992-02-25 | 1993-02-25 | Heterocyclic compounds |
NZ245995A NZ245995A (en) | 1992-02-25 | 1993-02-25 | Benzopyran, benzothiopyran and benzofuran derivatives and pharmaceutical compositions |
TNTNSN93020A TNSN93020A1 (fr) | 1992-02-25 | 1993-02-25 | Composes heterobicycliques |
EG1193A EG20333A (en) | 1992-02-25 | 1993-02-25 | Process for preparing benzopyran and benzothiopyran derivatives and their use as pharmaceutical agent for urinary tract disturbances |
TW082103988A TW382628B (en) | 1992-02-25 | 1993-05-20 | Heterobicyclic compounds and the use for the treatment of hypertension and urinary tract troubles |
KR1019940702823A KR950700276A (ko) | 1992-02-25 | 1994-08-17 | 헤테로고리 화합물(heterobicyclic compounds) |
BG98990A BG61946B1 (bg) | 1992-02-25 | 1994-08-19 | Хетеробициклични съединения |
FI943876A FI943876A0 (fi) | 1992-02-25 | 1994-08-23 | Heterobisykliset yhdisteet |
NO943140A NO943140L (no) | 1992-02-25 | 1994-08-25 | Heterobicykliske forbindelser |
US08/299,188 US5605896A (en) | 1992-02-25 | 1994-08-31 | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities |
EE9400374A EE03177B1 (et) | 1992-02-25 | 1994-11-10 | Heterobitsüklilised ühendid, nende saamismeetod ja nimetatud ühendeid sisaldavad farmatseutilised kompositsioonid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI920408A IT1254469B (it) | 1992-02-25 | 1992-02-25 | Derivati benzopiranici e benzotiopiranici |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI920408A0 ITMI920408A0 (it) | 1992-02-25 |
ITMI920408A1 ITMI920408A1 (it) | 1993-08-25 |
IT1254469B true IT1254469B (it) | 1995-09-25 |
Family
ID=11362122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI920408A IT1254469B (it) | 1992-02-25 | 1992-02-25 | Derivati benzopiranici e benzotiopiranici |
Country Status (6)
Country | Link |
---|---|
US (1) | US5403842A (it) |
KR (1) | KR950700276A (it) |
IT (1) | IT1254469B (it) |
RO (1) | RO112111B1 (it) |
RU (1) | RU2128656C1 (it) |
TN (1) | TNSN93020A1 (it) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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US6015819A (en) | 1992-11-13 | 2000-01-18 | Synaptic Pharmaceutical Corporation | Use of alpha-1C specific compounds to treat benign prostatic hyperplasia |
US5578611A (en) * | 1992-11-13 | 1996-11-26 | Synaptic Pharmaceutical Corporation | Use of α-1C specific compounds to treat benign prostatic hyperplasia |
US5503843A (en) * | 1994-04-22 | 1996-04-02 | Flora Inc. | Transdermal delivery of alpha adrenoceptor blocking agents |
DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
US6087366A (en) * | 1996-03-07 | 2000-07-11 | The Trustees Of Columbia University In The City Of New York | Use of flavopiridol or a pharmaceutically acceptable salt thereof for inhibiting cell damage or cell death |
US6410554B1 (en) | 1998-03-23 | 2002-06-25 | Merck & Co., Inc. | Combination therapy for the treatment of benign prostatic hyperplasia |
EP1075486A1 (en) * | 1998-05-06 | 2001-02-14 | Duke University | Method of treating bladder and lower urinary tract syndromes |
IT1312310B1 (it) | 1999-05-07 | 2002-04-15 | Recordati Ind Chimica E Farma | Uso di antagonisti selettivi del recettore adrenergico a 1b per ilmiglioramento della disfunzione sessuale |
DE60006954T2 (de) | 1999-05-10 | 2004-10-21 | Warner Lambert Co | Aromatische amide |
US6387909B1 (en) | 1999-07-30 | 2002-05-14 | Recordati S.A. Chemical And Pharmaceutical Company | Thienopyranecarboxamide derivatives |
US6306861B1 (en) | 1999-07-30 | 2001-10-23 | Recordati S.A. Chemical And Pharmaceutical Company | Thienopyrancecarboxamide derivatives |
US6403594B1 (en) | 1999-10-18 | 2002-06-11 | Recordati, S.A. Chemical And Pharmaceutical Company | Benzopyran derivatives |
IT1314191B1 (it) * | 1999-10-18 | 2002-12-06 | Recordati Chem Pharm | Derivati isossazolcarbossamidici |
US6365591B1 (en) | 1999-10-18 | 2002-04-02 | Recordati, S.A., Chemical And Pharmacueticals Company | Isoxazolecarboxamide derivatives |
SE0103650D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
SE0103647D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic chromone compounds |
NZ526697A (en) * | 2001-01-16 | 2005-05-27 | Astrazeneca Ab | Therapeutic heterocyclic compounds |
MXPA03006268A (es) | 2001-01-16 | 2003-09-22 | Astrazeneca Ab | Compuestos terapeuticos de cromano. |
US7247725B2 (en) * | 2002-10-30 | 2007-07-24 | Merck & Co., Inc. | Gamma-aminoamide modulators of chemokine receptor activity |
US6916831B2 (en) * | 2003-02-24 | 2005-07-12 | The University Of North Carolina At Chapel Hill | Flavone acetic acid analogs and methods of use thereof |
US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
WO2010037129A1 (en) * | 2008-09-29 | 2010-04-01 | Sirtris Pharmaceuticals Inc. | Quinazolinone, quinolone and related analogs as sirtuin modulators |
CN103819464B (zh) * | 2014-03-11 | 2015-10-07 | 南京工业大学 | 硫色满类化合物及其合成方法和制备抗真菌药物的应用 |
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KR20220124176A (ko) | 2019-12-06 | 2022-09-13 | 버텍스 파마슈티칼스 인코포레이티드 | 나트륨 채널의 조절제로서의 치환된 테트라하이드로푸란 |
CA3221259A1 (en) | 2021-06-04 | 2022-12-08 | Vertex Pharmaceuticals Incorporated | N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels |
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FR2637596B1 (fr) * | 1988-10-11 | 1992-09-04 | Irceba | Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant |
IE62890B1 (en) * | 1988-12-06 | 1995-03-08 | Hafslund Nycomed Pharma | New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure |
DE3918543A1 (de) * | 1989-06-07 | 1990-12-13 | Boehringer Mannheim Gmbh | Verwendung von naftopidil zur therapie der dysurie bei benigner prostata-hypertrophie |
JPH03173885A (ja) * | 1989-12-01 | 1991-07-29 | Mitsui Toatsu Chem Inc | ピリミジンジオン誘導体化合物、該化合物の製造法および該化合物を含む抗不整脈剤 |
FR2656609B1 (fr) * | 1989-12-28 | 1992-03-27 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
WO1991019707A2 (en) * | 1990-06-20 | 1991-12-26 | The Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
KR960014797B1 (ko) * | 1990-07-25 | 1996-10-19 | 이다가끼 히로시 | 벤조피란 유도체, 그의 제조법 및 그것을 함유하는 의약 조성물 |
ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
JPH05125024A (ja) * | 1991-11-05 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアリールオキシアルキルアミン誘導体又はその塩 |
-
1992
- 1992-02-25 IT ITMI920408A patent/IT1254469B/it active IP Right Grant
- 1992-05-26 US US07/888,775 patent/US5403842A/en not_active Expired - Fee Related
-
1993
- 1993-02-23 RU RU94043324A patent/RU2128656C1/ru active
- 1993-02-23 RO RO94-01404A patent/RO112111B1/ro unknown
- 1993-02-25 TN TNTNSN93020A patent/TNSN93020A1/fr unknown
-
1994
- 1994-08-17 KR KR1019940702823A patent/KR950700276A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ITMI920408A0 (it) | 1992-02-25 |
RU94043324A (ru) | 1996-08-20 |
TNSN93020A1 (fr) | 1994-03-17 |
US5403842A (en) | 1995-04-04 |
KR950700276A (ko) | 1995-01-16 |
ITMI920408A1 (it) | 1993-08-25 |
RU2128656C1 (ru) | 1999-04-10 |
RO112111B1 (ro) | 1997-05-30 |
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Legal Events
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970129 |