ES2151991T3 - Procedimiento para preparar un derivado de tieno(2,3-b)(1,5)benzodiacepina. - Google Patents

Procedimiento para preparar un derivado de tieno(2,3-b)(1,5)benzodiacepina.

Info

Publication number
ES2151991T3
ES2151991T3 ES96301999T ES96301999T ES2151991T3 ES 2151991 T3 ES2151991 T3 ES 2151991T3 ES 96301999 T ES96301999 T ES 96301999T ES 96301999 T ES96301999 T ES 96301999T ES 2151991 T3 ES2151991 T3 ES 2151991T3
Authority
ES
Spain
Prior art keywords
benzodiacepin
tenan
derivative
prepare
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96301999T
Other languages
English (en)
Inventor
Charles Arthur Bunnell
Barry Arnold Hendriksen
Terrence Michael Hotten
Samuel Dean Larsen
David Edward Tupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co Ltd
Eli Lilly and Co
Original Assignee
Eli Lilly and Co Ltd
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2151991(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/410,474 external-priority patent/US5631250A/en
Application filed by Eli Lilly and Co Ltd, Eli Lilly and Co filed Critical Eli Lilly and Co Ltd
Application granted granted Critical
Publication of ES2151991T3 publication Critical patent/ES2151991T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION PROPORCIONA SOLVATOS DE METANOL, ETANOL Y 1PROPANOL DE OLANZAPINA (FORMULA (I)) Y UN PROCESO PARA UTILIZAR DICHOS SOLVATOS.
ES96301999T 1995-03-24 1996-03-22 Procedimiento para preparar un derivado de tieno(2,3-b)(1,5)benzodiacepina. Expired - Lifetime ES2151991T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24
US08/410,474 US5631250A (en) 1995-03-24 1995-03-24 Process and solvate of 2-methyl-thieno-benzodiazepine

Publications (1)

Publication Number Publication Date
ES2151991T3 true ES2151991T3 (es) 2001-01-16

Family

ID=27020696

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96301999T Expired - Lifetime ES2151991T3 (es) 1995-03-24 1996-03-22 Procedimiento para preparar un derivado de tieno(2,3-b)(1,5)benzodiacepina.

Country Status (17)

Country Link
EP (1) EP0733634B1 (es)
AR (2) AR002721A1 (es)
AT (1) ATE197711T1 (es)
AU (1) AU5257896A (es)
CO (1) CO4700300A1 (es)
DE (1) DE69611003T2 (es)
DK (1) DK0733634T3 (es)
EG (1) EG24221A (es)
ES (1) ES2151991T3 (es)
GR (1) GR3035355T3 (es)
IL (1) IL117613A (es)
MY (1) MY116503A (es)
PE (1) PE38197A1 (es)
PT (1) PT733634E (es)
SI (1) SI0733634T1 (es)
WO (1) WO1996030374A1 (es)
YU (1) YU49276B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
CN1146567C (zh) * 1996-09-23 2004-04-21 伊莱利利公司 奥氮平二水合物d
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
WO2003101997A1 (en) 2002-05-31 2003-12-11 Geneva Pharmaceuticals, Inc. Process of preparation of olanzapine form i
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
EP1575962A1 (en) 2002-12-24 2005-09-21 Teva Pharmaceutical Industries Limited Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
CA2551806A1 (en) 2003-12-22 2005-07-14 Teva Pharmaceutical Industries, Ltd. Methods of preparing olanzapine
US20070072845A1 (en) * 2004-02-19 2007-03-29 Davuluri Rammohan Rao Process for the preparation of olanzapine form 1 useful as antipsychotic drug
ES2253091B1 (es) * 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
ATE511512T1 (de) 2005-01-05 2011-06-15 Lilly Co Eli Olanzapinpamoat-dihydrat
CA2593407A1 (en) * 2007-06-22 2008-12-22 Apotex Pharmachem Inc. Improved processes for the synthesis of olanzapine
CU20090172A6 (es) 2009-10-09 2011-10-05 Facultad De Quimica Universidad De La Habana Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
CA2097016A1 (en) * 1992-05-29 1993-11-30 John Fairhurst Pharmaceutical compounds
US5439888A (en) * 1994-03-04 1995-08-08 Eli Lilly And Company Antithrombotic agents
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use

Also Published As

Publication number Publication date
AR004169A1 (es) 1998-11-04
EG24221A (en) 2008-11-10
SI0733634T1 (en) 2001-06-30
YU17696A (sh) 1998-07-10
AR002721A1 (es) 1998-04-29
ATE197711T1 (de) 2000-12-15
EP0733634A1 (en) 1996-09-25
PT733634E (pt) 2001-04-30
DE69611003D1 (de) 2000-12-28
WO1996030374A1 (en) 1996-10-03
GR3035355T3 (en) 2001-05-31
YU49276B (sh) 2005-03-15
EP0733634B1 (en) 2000-11-22
MY116503A (en) 2004-02-28
DK0733634T3 (da) 2000-12-11
IL117613A0 (en) 1996-07-23
CO4700300A1 (es) 1998-12-29
AU5257896A (en) 1996-10-16
DE69611003T2 (de) 2001-05-10
IL117613A (en) 2000-07-16
PE38197A1 (es) 1997-10-16

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