EE05442B1 - V„ikeses annuses entekaviiri sisaldav ravimkoostis B-hepatiidi viirusinfektsiooni raviks ning meetod selle valmistamiseks - Google Patents

V„ikeses annuses entekaviiri sisaldav ravimkoostis B-hepatiidi viirusinfektsiooni raviks ning meetod selle valmistamiseks

Info

Publication number
EE05442B1
EE05442B1 EEP200200484A EEP200200484A EE05442B1 EE 05442 B1 EE05442 B1 EE 05442B1 EE P200200484 A EEP200200484 A EE P200200484A EE P200200484 A EEP200200484 A EE P200200484A EE 05442 B1 EE05442 B1 EE 05442B1
Authority
EE
Estonia
Prior art keywords
hepatitis
preparation
treatment
pharmaceutical composition
virus infection
Prior art date
Application number
EEP200200484A
Other languages
English (en)
Estonian (et)
Inventor
J. Colonno Richard
L. Sprockel Omar
Harianawala Abizer
S. Desai Divyakant
G. Fakes Michael
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26881354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE05442(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of EE200200484A publication Critical patent/EE200200484A/xx
Publication of EE05442B1 publication Critical patent/EE05442B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
EEP200200484A 2000-02-29 2001-01-26 V„ikeses annuses entekaviiri sisaldav ravimkoostis B-hepatiidi viirusinfektsiooni raviks ning meetod selle valmistamiseks EE05442B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18567200P 2000-02-29 2000-02-29
US22131300P 2000-07-28 2000-07-28
PCT/US2001/002630 WO2001064221A1 (en) 2000-02-29 2001-01-26 Low dose entecavir formulation and use

Publications (2)

Publication Number Publication Date
EE200200484A EE200200484A (et) 2004-04-15
EE05442B1 true EE05442B1 (et) 2011-08-15

Family

ID=26881354

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200484A EE05442B1 (et) 2000-02-29 2001-01-26 V„ikeses annuses entekaviiri sisaldav ravimkoostis B-hepatiidi viirusinfektsiooni raviks ning meetod selle valmistamiseks

Country Status (35)

Country Link
US (1) US6627224B2 (cs)
EP (2) EP1642582A1 (cs)
JP (3) JP5140222B2 (cs)
KR (1) KR100757155B1 (cs)
AR (1) AR027965A1 (cs)
AT (1) ATE312613T1 (cs)
AU (1) AU2001229775A1 (cs)
BG (1) BG65815B1 (cs)
BR (1) BRPI0108435B8 (cs)
CA (1) CA2401569C (cs)
CO (1) CO5261593A1 (cs)
CZ (1) CZ303395B6 (cs)
DE (1) DE60115870T3 (cs)
DK (1) DK1267880T4 (cs)
EA (1) EA006181B1 (cs)
EE (1) EE05442B1 (cs)
EG (1) EG24408A (cs)
ES (1) ES2253403T5 (cs)
GE (1) GEP20053504B (cs)
HK (1) HK1048771A1 (cs)
HR (1) HRP20020649A2 (cs)
HU (1) HU230698B1 (cs)
IL (1) IL150447A0 (cs)
MX (1) MXPA02008359A (cs)
MY (1) MY127422A (cs)
NO (1) NO324014B1 (cs)
NZ (1) NZ520024A (cs)
PE (1) PE20020770A1 (cs)
PL (1) PL201411B1 (cs)
RS (1) RS51561B (cs)
SI (1) SI1267880T2 (cs)
SK (1) SK288008B6 (cs)
TW (1) TWI287988B (cs)
UA (1) UA84534C2 (cs)
WO (1) WO2001064221A1 (cs)

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CA2460340C (en) 2001-09-21 2011-02-15 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
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TWI275392B (en) * 2002-04-08 2007-03-11 Bristol Myers Squibb Co Low dose liquid entecavir formulations and use
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CN103908436B (zh) * 2012-12-29 2016-02-10 安徽贝克生物制药有限公司 一种速释型恩替卡韦组合物
KR101512895B1 (ko) 2013-08-09 2015-04-16 대화제약 주식회사 엔테카비어를 포함하는 약학적 조성물의 제조방법
CN106573003B (zh) * 2014-06-20 2022-04-01 西梯茜生命工学股份有限公司 含有恩替卡韦作为活性成分的药物制剂及其制备方法
JP6625878B2 (ja) * 2015-01-26 2019-12-25 沢井製薬株式会社 エンテカビル含有錠剤、その製造方法及びそれを用いた口腔内崩壊錠
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WO2021058021A1 (zh) 2019-09-29 2021-04-01 正大天晴药业集团股份有限公司 包含tlr7激动剂的药物组合
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Also Published As

Publication number Publication date
EA006181B1 (ru) 2005-10-27
SI1267880T2 (sl) 2010-04-30
PE20020770A1 (es) 2002-09-06
EE200200484A (et) 2004-04-15
CA2401569A1 (en) 2001-09-07
SK11652002A3 (sk) 2003-09-11
YU63002A (sh) 2005-03-15
IL150447A0 (en) 2002-12-01
SK288008B6 (sk) 2012-10-02
KR20020082230A (ko) 2002-10-30
BRPI0108435B8 (pt) 2021-05-25
JP2015178523A (ja) 2015-10-08
RS51561B (sr) 2011-08-31
EA200200812A1 (ru) 2003-12-25
EG24408A (en) 2009-05-20
JP2012255017A (ja) 2012-12-27
HRP20020649A2 (en) 2004-12-31
EP1267880B1 (en) 2005-12-14
JP5140222B2 (ja) 2013-02-06
HU230698B1 (hu) 2017-09-28
AU2001229775A1 (en) 2001-09-12
US20010033864A1 (en) 2001-10-25
NO324014B1 (no) 2007-07-30
BG65815B1 (bg) 2010-01-29
DK1267880T4 (da) 2010-05-17
BR0108435A (pt) 2004-06-15
JP5921746B2 (ja) 2016-05-24
ES2253403T5 (es) 2010-04-22
NO20024099D0 (no) 2002-08-28
PL366102A1 (en) 2005-01-24
EP1267880A1 (en) 2003-01-02
HUP0500558A3 (en) 2012-08-28
DE60115870D1 (de) 2006-01-19
BG106905A (bg) 2003-04-30
HK1048771A1 (zh) 2003-04-17
UA84534C2 (uk) 2008-11-10
KR100757155B1 (ko) 2007-09-07
EP1267880B2 (en) 2010-01-20
MY127422A (en) 2006-11-30
DE60115870T2 (de) 2006-08-17
US6627224B2 (en) 2003-09-30
CZ303395B6 (cs) 2012-08-29
ATE312613T1 (de) 2005-12-15
PL201411B1 (pl) 2009-04-30
GEP20053504B (en) 2005-05-10
JP2004503467A (ja) 2004-02-05
DK1267880T3 (da) 2006-03-06
EP1642582A1 (en) 2006-04-05
WO2001064221A1 (en) 2001-09-07
CA2401569C (en) 2009-08-18
BRPI0108435B1 (pt) 2019-02-05
NO20024099L (no) 2002-08-28
DE60115870T3 (de) 2010-07-29
MXPA02008359A (es) 2003-02-12
ES2253403T3 (es) 2006-06-01
SI1267880T1 (sl) 2006-06-30
AR027965A1 (es) 2003-04-16
HUP0500558A2 (hu) 2005-09-28
CO5261593A1 (es) 2003-03-31
NZ520024A (en) 2005-03-24
TWI287988B (en) 2007-10-11

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