EE04798B1 - Zofenopriili kaltsiumisoola valmistamise meetod - Google Patents

Zofenopriili kaltsiumisoola valmistamise meetod

Info

Publication number
EE04798B1
EE04798B1 EEP200100065A EEP200100065A EE04798B1 EE 04798 B1 EE04798 B1 EE 04798B1 EE P200100065 A EEP200100065 A EE P200100065A EE P200100065 A EEP200100065 A EE P200100065A EE 04798 B1 EE04798 B1 EE 04798B1
Authority
EE
Estonia
Prior art keywords
zofenopril
salt
calcium salt
preparation
potassium salt
Prior art date
Application number
EEP200100065A
Other languages
English (en)
Inventor
Giorgi Raffaello (Surnud)
Giachetti Antonio
Mannucci Carlo
Falezza Anita
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of EE200100065A publication Critical patent/EE200100065A/et
Publication of EE04798B1 publication Critical patent/EE04798B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00—Compounds of calcium, strontium, or barium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
EEP200100065A 1998-08-04 1999-07-30 Zofenopriili kaltsiumisoola valmistamise meetod EE04798B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001833A IT1301993B1 (it) 1998-08-04 1998-08-04 Processo per la preparazione di zofenopril sale di calcio.
PCT/EP1999/005461 WO2000007984A1 (en) 1998-08-04 1999-07-30 A process for the preparation of zofenopril calcium salt

Publications (2)

Publication Number Publication Date
EE200100065A EE200100065A (et) 2002-06-17
EE04798B1 true EE04798B1 (et) 2007-04-16

Family

ID=11380611

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100065A EE04798B1 (et) 1998-08-04 1999-07-30 Zofenopriili kaltsiumisoola valmistamise meetod

Country Status (32)

Country Link
US (2) US6521760B1 (et)
EP (1) EP1102745B1 (et)
JP (1) JP2002522417A (et)
KR (1) KR100593428B1 (et)
CN (1) CN1146538C (et)
AT (1) ATE266635T1 (et)
AU (1) AU5372299A (et)
BG (1) BG65022B1 (et)
BR (1) BR9912842A (et)
CA (1) CA2339283C (et)
CU (1) CU23171A3 (et)
CZ (1) CZ301908B6 (et)
DE (1) DE69917282T2 (et)
DK (1) DK1102745T3 (et)
EA (1) EA003454B1 (et)
EE (1) EE04798B1 (et)
ES (1) ES2221417T3 (et)
HK (1) HK1039616B (et)
HR (1) HRP20010083B1 (et)
HU (1) HU227557B1 (et)
IL (1) IL141222A0 (et)
IT (1) IT1301993B1 (et)
NO (1) NO319773B1 (et)
PL (1) PL193828B1 (et)
PT (1) PT1102745E (et)
RS (1) RS49768B (et)
SI (1) SI1102745T1 (et)
SK (1) SK285527B6 (et)
TR (1) TR200100272T2 (et)
UA (1) UA65628C2 (et)
WO (1) WO2000007984A1 (et)
ZA (1) ZA200100907B (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1899297T3 (pl) * 2005-07-01 2016-06-30 Generics Uk Ltd Zofenopryl wapnia w postaci polimorficznej c
EA012845B1 (ru) * 2005-12-09 2009-12-30 Менарини Интернэшнл Оперейшнс Люксембург С. А. Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии
RS53733B1 (en) * 2006-05-26 2015-06-30 Generics PROCEDURES FOR PREPARATION OF ZOFENOPRIL CALCIUM
GB0715626D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Crystalline form of zofenopril calcium
US8853421B2 (en) 2008-02-27 2014-10-07 Generics [Uk] Limited Crystalline forms of zofenopril calcium
US20110118328A1 (en) * 2008-02-27 2011-05-19 Vinayak Gore Novel crystalline forms
EP2389360A4 (en) * 2009-01-23 2013-01-16 Glenmark Generics Ltd METHOD FOR PRODUCING ZOFENOPRIL AND PHARMACEUTICAL ACCEPTIC SALTS THEREFOR
SI23949A (sl) 2011-12-19 2013-06-28 Silverstone Pharma Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji
CN104138359B (zh) * 2013-05-06 2016-03-02 扬子江药业集团上海海尼药业有限公司 佐芬普利钙片的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4154935A (en) * 1978-02-21 1979-05-15 E. R. Squibb & Sons, Inc. Halogen substituted mercaptoacylamino acids
US4316906A (en) * 1978-08-11 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of substituted prolines

Also Published As

Publication number Publication date
AU5372299A (en) 2000-02-28
IL141222A0 (en) 2002-03-10
CZ301908B6 (cs) 2010-07-28
EP1102745B1 (en) 2004-05-12
EA200100095A1 (ru) 2001-08-27
SK285527B6 (sk) 2007-03-01
WO2000007984A1 (en) 2000-02-17
HK1039616A1 (en) 2002-05-03
KR100593428B1 (ko) 2006-06-28
NO20010552D0 (no) 2001-02-01
CN1316992A (zh) 2001-10-10
US6515012B2 (en) 2003-02-04
CU23171A3 (es) 2006-09-22
HRP20010083A2 (en) 2002-02-28
HUP0103826A3 (en) 2002-03-28
YU7501A (sh) 2005-06-10
PL193828B1 (pl) 2007-03-30
BG105176A (en) 2001-11-30
ES2221417T3 (es) 2004-12-16
ATE266635T1 (de) 2004-05-15
BR9912842A (pt) 2001-10-16
DE69917282D1 (de) 2004-06-17
IT1301993B1 (it) 2000-07-20
RS49768B (sr) 2008-06-05
JP2002522417A (ja) 2002-07-23
ITMI981833A1 (it) 2000-02-04
BG65022B1 (bg) 2006-12-29
ZA200100907B (en) 2001-10-04
DE69917282T2 (de) 2005-05-25
SI1102745T1 (en) 2004-10-31
CA2339283C (en) 2009-03-17
EA003454B1 (ru) 2003-06-26
PL345814A1 (en) 2002-01-14
ITMI981833A0 (it) 1998-08-04
CA2339283A1 (en) 2000-02-17
NO20010552L (no) 2001-02-01
HRP20010083B1 (en) 2005-02-28
EE200100065A (et) 2002-06-17
EP1102745A1 (en) 2001-05-30
US20020156293A1 (en) 2002-10-24
NO319773B1 (no) 2005-09-12
TR200100272T2 (tr) 2001-05-21
US6521760B1 (en) 2003-02-18
SK1632001A3 (en) 2001-09-11
KR20010072171A (ko) 2001-07-31
CN1146538C (zh) 2004-04-21
HUP0103826A2 (hu) 2002-02-28
HK1039616B (zh) 2004-10-08
PT1102745E (pt) 2004-08-31
UA65628C2 (uk) 2004-04-15
DK1102745T3 (da) 2004-08-02
HU227557B1 (en) 2011-08-29
CZ2001408A3 (cs) 2001-07-11

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231