DK1102745T3 - Fremgangsmåde til fremstilling af zofenoprilcalciumsalt - Google Patents

Fremgangsmåde til fremstilling af zofenoprilcalciumsalt

Info

Publication number
DK1102745T3
DK1102745T3 DK99939416T DK99939416T DK1102745T3 DK 1102745 T3 DK1102745 T3 DK 1102745T3 DK 99939416 T DK99939416 T DK 99939416T DK 99939416 T DK99939416 T DK 99939416T DK 1102745 T3 DK1102745 T3 DK 1102745T3
Authority
DK
Denmark
Prior art keywords
zofenopril
salt
calcium salt
preparation
potassium salt
Prior art date
Application number
DK99939416T
Other languages
English (en)
Inventor
Raffaello Giorgi
Antonio Giachetti
Carlo Mannucci
Anita Falezza
Original Assignee
Menarini Int Operations Lu Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Int Operations Lu Sa filed Critical Menarini Int Operations Lu Sa
Application granted granted Critical
Publication of DK1102745T3 publication Critical patent/DK1102745T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01FCOMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00Compounds of calcium, strontium, or barium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99939416T 1998-08-04 1999-07-30 Fremgangsmåde til fremstilling af zofenoprilcalciumsalt DK1102745T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI001833A IT1301993B1 (it) 1998-08-04 1998-08-04 Processo per la preparazione di zofenopril sale di calcio.

Publications (1)

Publication Number Publication Date
DK1102745T3 true DK1102745T3 (da) 2004-08-02

Family

ID=11380611

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99939416T DK1102745T3 (da) 1998-08-04 1999-07-30 Fremgangsmåde til fremstilling af zofenoprilcalciumsalt

Country Status (32)

Country Link
US (2) US6521760B1 (da)
EP (1) EP1102745B1 (da)
JP (1) JP2002522417A (da)
KR (1) KR100593428B1 (da)
CN (1) CN1146538C (da)
AT (1) ATE266635T1 (da)
AU (1) AU5372299A (da)
BG (1) BG65022B1 (da)
BR (1) BR9912842A (da)
CA (1) CA2339283C (da)
CU (1) CU23171A3 (da)
CZ (1) CZ301908B6 (da)
DE (1) DE69917282T2 (da)
DK (1) DK1102745T3 (da)
EA (1) EA003454B1 (da)
EE (1) EE04798B1 (da)
ES (1) ES2221417T3 (da)
HK (1) HK1039616B (da)
HR (1) HRP20010083B1 (da)
HU (1) HU227557B1 (da)
IL (1) IL141222A0 (da)
IT (1) IT1301993B1 (da)
NO (1) NO319773B1 (da)
PL (1) PL193828B1 (da)
PT (1) PT1102745E (da)
RS (1) RS49768B (da)
SI (1) SI1102745T1 (da)
SK (1) SK285527B6 (da)
TR (1) TR200100272T2 (da)
UA (1) UA65628C2 (da)
WO (1) WO2000007984A1 (da)
ZA (1) ZA200100907B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2560502T3 (es) 2005-07-01 2016-02-19 Generics [Uk] Limited Zofenopril calcio en forma de polimorfo C
EA012845B1 (ru) * 2005-12-09 2009-12-30 Менарини Интернэшнл Оперейшнс Люксембург С. А. Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии
DK2041083T3 (da) * 2006-05-26 2015-01-26 Generics Uk Ltd Fremgangsmåder til fremstilling af zofenoprilkalcium
GB0715626D0 (en) 2007-08-10 2007-09-19 Generics Uk Ltd Crystalline form of zofenopril calcium
US8853421B2 (en) 2008-02-27 2014-10-07 Generics [Uk] Limited Crystalline forms of zofenopril calcium
CN101981004B (zh) * 2008-02-27 2014-09-17 基因里克斯(英国)有限公司 晶体形式
EP2389360A4 (en) * 2009-01-23 2013-01-16 Glenmark Generics Ltd METHOD FOR PRODUCING ZOFENOPRIL AND PHARMACEUTICAL ACCEPTIC SALTS THEREFOR
SI23949A (sl) 2011-12-19 2013-06-28 Silverstone Pharma Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji
CN104138359B (zh) * 2013-05-06 2016-03-02 扬子江药业集团上海海尼药业有限公司 佐芬普利钙片的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4154935A (en) * 1978-02-21 1979-05-15 E. R. Squibb & Sons, Inc. Halogen substituted mercaptoacylamino acids
US4316906A (en) 1978-08-11 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of substituted prolines

Also Published As

Publication number Publication date
HUP0103826A3 (en) 2002-03-28
CZ301908B6 (cs) 2010-07-28
PT1102745E (pt) 2004-08-31
IT1301993B1 (it) 2000-07-20
ITMI981833A1 (it) 2000-02-04
NO319773B1 (no) 2005-09-12
CU23171A3 (es) 2006-09-22
ES2221417T3 (es) 2004-12-16
SK1632001A3 (en) 2001-09-11
DE69917282D1 (de) 2004-06-17
CA2339283C (en) 2009-03-17
CN1316992A (zh) 2001-10-10
US6521760B1 (en) 2003-02-18
CZ2001408A3 (cs) 2001-07-11
BG65022B1 (bg) 2006-12-29
HU227557B1 (en) 2011-08-29
EE04798B1 (et) 2007-04-16
BG105176A (en) 2001-11-30
PL193828B1 (pl) 2007-03-30
HRP20010083A2 (en) 2002-02-28
ATE266635T1 (de) 2004-05-15
HK1039616A1 (en) 2002-05-03
TR200100272T2 (tr) 2001-05-21
ZA200100907B (en) 2001-10-04
HUP0103826A2 (hu) 2002-02-28
KR20010072171A (ko) 2001-07-31
NO20010552L (no) 2001-02-01
SK285527B6 (sk) 2007-03-01
UA65628C2 (uk) 2004-04-15
IL141222A0 (en) 2002-03-10
US20020156293A1 (en) 2002-10-24
EA003454B1 (ru) 2003-06-26
EP1102745B1 (en) 2004-05-12
BR9912842A (pt) 2001-10-16
KR100593428B1 (ko) 2006-06-28
RS49768B (sr) 2008-06-05
EE200100065A (et) 2002-06-17
AU5372299A (en) 2000-02-28
EP1102745A1 (en) 2001-05-30
US6515012B2 (en) 2003-02-04
ITMI981833A0 (it) 1998-08-04
EA200100095A1 (ru) 2001-08-27
HRP20010083B1 (en) 2005-02-28
CA2339283A1 (en) 2000-02-17
WO2000007984A1 (en) 2000-02-17
JP2002522417A (ja) 2002-07-23
NO20010552D0 (no) 2001-02-01
PL345814A1 (en) 2002-01-14
YU7501A (sh) 2005-06-10
SI1102745T1 (en) 2004-10-31
HK1039616B (zh) 2004-10-08
DE69917282T2 (de) 2005-05-25
CN1146538C (zh) 2004-04-21

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