ATE266635T1 - Verfahren zur herstellung von zofenopril- calciumsalz - Google Patents
Verfahren zur herstellung von zofenopril- calciumsalzInfo
- Publication number
- ATE266635T1 ATE266635T1 AT99939416T AT99939416T ATE266635T1 AT E266635 T1 ATE266635 T1 AT E266635T1 AT 99939416 T AT99939416 T AT 99939416T AT 99939416 T AT99939416 T AT 99939416T AT E266635 T1 ATE266635 T1 AT E266635T1
- Authority
- AT
- Austria
- Prior art keywords
- zofenopril
- calcium salt
- salt
- producing
- potassium salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI001833A IT1301993B1 (it) | 1998-08-04 | 1998-08-04 | Processo per la preparazione di zofenopril sale di calcio. |
PCT/EP1999/005461 WO2000007984A1 (en) | 1998-08-04 | 1999-07-30 | A process for the preparation of zofenopril calcium salt |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE266635T1 true ATE266635T1 (de) | 2004-05-15 |
Family
ID=11380611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99939416T ATE266635T1 (de) | 1998-08-04 | 1999-07-30 | Verfahren zur herstellung von zofenopril- calciumsalz |
Country Status (32)
Country | Link |
---|---|
US (2) | US6521760B1 (de) |
EP (1) | EP1102745B1 (de) |
JP (1) | JP2002522417A (de) |
KR (1) | KR100593428B1 (de) |
CN (1) | CN1146538C (de) |
AT (1) | ATE266635T1 (de) |
AU (1) | AU5372299A (de) |
BG (1) | BG65022B1 (de) |
BR (1) | BR9912842A (de) |
CA (1) | CA2339283C (de) |
CU (1) | CU23171A3 (de) |
CZ (1) | CZ301908B6 (de) |
DE (1) | DE69917282T2 (de) |
DK (1) | DK1102745T3 (de) |
EA (1) | EA003454B1 (de) |
EE (1) | EE04798B1 (de) |
ES (1) | ES2221417T3 (de) |
HK (1) | HK1039616B (de) |
HR (1) | HRP20010083B1 (de) |
HU (1) | HU227557B1 (de) |
IL (1) | IL141222A0 (de) |
IT (1) | IT1301993B1 (de) |
NO (1) | NO319773B1 (de) |
PL (1) | PL193828B1 (de) |
PT (1) | PT1102745E (de) |
RS (1) | RS49768B (de) |
SI (1) | SI1102745T1 (de) |
SK (1) | SK285527B6 (de) |
TR (1) | TR200100272T2 (de) |
UA (1) | UA65628C2 (de) |
WO (1) | WO2000007984A1 (de) |
ZA (1) | ZA200100907B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1899297E (pt) * | 2005-07-01 | 2016-03-21 | Generics Uk Ltd | Zofenopril de cálcio em forma polimórfica c |
EA012845B1 (ru) * | 2005-12-09 | 2009-12-30 | Менарини Интернэшнл Оперейшнс Люксембург С. А. | Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии |
CA2653333C (en) * | 2006-05-26 | 2012-07-31 | Generics (Uk) Limited | Zofenopril calcium |
GB0715626D0 (en) * | 2007-08-10 | 2007-09-19 | Generics Uk Ltd | Crystalline form of zofenopril calcium |
US8853421B2 (en) | 2008-02-27 | 2014-10-07 | Generics [Uk] Limited | Crystalline forms of zofenopril calcium |
AU2009219892B2 (en) * | 2008-02-27 | 2014-08-07 | Generics [Uk] Limited | Novel crystalline forms |
WO2010084515A2 (en) * | 2009-01-23 | 2010-07-29 | Glenmark Generics Limited | A process for the preparation of zofenopril and its pharmaceutically acceptable salts thereof |
SI23949A (sl) | 2011-12-19 | 2013-06-28 | Silverstone Pharma | Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji |
CN104138359B (zh) * | 2013-05-06 | 2016-03-02 | 扬子江药业集团上海海尼药业有限公司 | 佐芬普利钙片的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
US4316906A (en) * | 1978-08-11 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of substituted prolines |
-
1998
- 1998-08-04 IT IT1998MI001833A patent/IT1301993B1/it active IP Right Grant
-
1999
- 1999-07-30 EE EEP200100065A patent/EE04798B1/xx unknown
- 1999-07-30 JP JP2000563619A patent/JP2002522417A/ja active Pending
- 1999-07-30 DE DE69917282T patent/DE69917282T2/de not_active Expired - Lifetime
- 1999-07-30 TR TR2001/00272T patent/TR200100272T2/xx unknown
- 1999-07-30 CA CA002339283A patent/CA2339283C/en not_active Expired - Lifetime
- 1999-07-30 EP EP99939416A patent/EP1102745B1/de not_active Expired - Lifetime
- 1999-07-30 PT PT99939416T patent/PT1102745E/pt unknown
- 1999-07-30 CN CNB998105171A patent/CN1146538C/zh not_active Expired - Lifetime
- 1999-07-30 ES ES99939416T patent/ES2221417T3/es not_active Expired - Lifetime
- 1999-07-30 WO PCT/EP1999/005461 patent/WO2000007984A1/en active IP Right Grant
- 1999-07-30 AU AU53722/99A patent/AU5372299A/en not_active Abandoned
- 1999-07-30 AT AT99939416T patent/ATE266635T1/de active
- 1999-07-30 SI SI9930575T patent/SI1102745T1/xx unknown
- 1999-07-30 DK DK99939416T patent/DK1102745T3/da active
- 1999-07-30 SK SK163-2001A patent/SK285527B6/sk not_active IP Right Cessation
- 1999-07-30 CZ CZ20010408A patent/CZ301908B6/cs not_active IP Right Cessation
- 1999-07-30 BR BR9912842-0A patent/BR9912842A/pt not_active Application Discontinuation
- 1999-07-30 IL IL14122299A patent/IL141222A0/xx not_active IP Right Cessation
- 1999-07-30 HU HU0103826A patent/HU227557B1/hu unknown
- 1999-07-30 EA EA200100095A patent/EA003454B1/ru not_active IP Right Cessation
- 1999-07-30 RS YUP-75/01A patent/RS49768B/sr unknown
- 1999-07-30 KR KR1020017001379A patent/KR100593428B1/ko not_active IP Right Cessation
- 1999-07-30 PL PL99345814A patent/PL193828B1/pl unknown
- 1999-07-30 US US09/762,054 patent/US6521760B1/en not_active Expired - Fee Related
- 1999-07-30 UA UA2001010590A patent/UA65628C2/uk unknown
-
2001
- 2001-01-24 BG BG105176A patent/BG65022B1/bg unknown
- 2001-02-01 HR HR20010083A patent/HRP20010083B1/xx not_active IP Right Cessation
- 2001-02-01 ZA ZA200100907A patent/ZA200100907B/en unknown
- 2001-02-01 NO NO20010552A patent/NO319773B1/no not_active IP Right Cessation
- 2001-02-01 CU CU20010032A patent/CU23171A3/es unknown
-
2002
- 2002-02-21 HK HK02101248.6A patent/HK1039616B/zh not_active IP Right Cessation
- 2002-05-28 US US10/155,129 patent/US6515012B2/en not_active Expired - Fee Related
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Legal Events
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