DE69917282D1 - Verfahren zur herstellung von zofenopril-calciumsalz - Google Patents
Verfahren zur herstellung von zofenopril-calciumsalzInfo
- Publication number
- DE69917282D1 DE69917282D1 DE69917282T DE69917282T DE69917282D1 DE 69917282 D1 DE69917282 D1 DE 69917282D1 DE 69917282 T DE69917282 T DE 69917282T DE 69917282 T DE69917282 T DE 69917282T DE 69917282 D1 DE69917282 D1 DE 69917282D1
- Authority
- DE
- Germany
- Prior art keywords
- zofenopril
- salt
- zofenoprile
- producing
- potassium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI981833 | 1998-08-04 | ||
IT1998MI001833A IT1301993B1 (it) | 1998-08-04 | 1998-08-04 | Processo per la preparazione di zofenopril sale di calcio. |
PCT/EP1999/005461 WO2000007984A1 (en) | 1998-08-04 | 1999-07-30 | A process for the preparation of zofenopril calcium salt |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69917282D1 true DE69917282D1 (de) | 2004-06-17 |
DE69917282T2 DE69917282T2 (de) | 2005-05-25 |
Family
ID=11380611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69917282T Expired - Lifetime DE69917282T2 (de) | 1998-08-04 | 1999-07-30 | Verfahren zur herstellung von zofenopril-calciumsalz |
Country Status (32)
Country | Link |
---|---|
US (2) | US6521760B1 (de) |
EP (1) | EP1102745B1 (de) |
JP (1) | JP2002522417A (de) |
KR (1) | KR100593428B1 (de) |
CN (1) | CN1146538C (de) |
AT (1) | ATE266635T1 (de) |
AU (1) | AU5372299A (de) |
BG (1) | BG65022B1 (de) |
BR (1) | BR9912842A (de) |
CA (1) | CA2339283C (de) |
CU (1) | CU23171A3 (de) |
CZ (1) | CZ301908B6 (de) |
DE (1) | DE69917282T2 (de) |
DK (1) | DK1102745T3 (de) |
EA (1) | EA003454B1 (de) |
EE (1) | EE04798B1 (de) |
ES (1) | ES2221417T3 (de) |
HK (1) | HK1039616B (de) |
HR (1) | HRP20010083B1 (de) |
HU (1) | HU227557B1 (de) |
IL (1) | IL141222A0 (de) |
IT (1) | IT1301993B1 (de) |
NO (1) | NO319773B1 (de) |
PL (1) | PL193828B1 (de) |
PT (1) | PT1102745E (de) |
RS (1) | RS49768B (de) |
SI (1) | SI1102745T1 (de) |
SK (1) | SK285527B6 (de) |
TR (1) | TR200100272T2 (de) |
UA (1) | UA65628C2 (de) |
WO (1) | WO2000007984A1 (de) |
ZA (1) | ZA200100907B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1899297B1 (de) | 2005-07-01 | 2015-12-09 | Generics [UK] Limited | Zofenopril-calcium in der polymorphform c |
EA012845B1 (ru) * | 2005-12-09 | 2009-12-30 | Менарини Интернэшнл Оперейшнс Люксембург С. А. | Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии |
AU2007266837A1 (en) * | 2006-05-26 | 2007-12-06 | Generics [Uk] Limited | Zofenopril calcium |
GB0715626D0 (en) * | 2007-08-10 | 2007-09-19 | Generics Uk Ltd | Crystalline form of zofenopril calcium |
CN101981004B (zh) * | 2008-02-27 | 2014-09-17 | 基因里克斯(英国)有限公司 | 晶体形式 |
US8853421B2 (en) | 2008-02-27 | 2014-10-07 | Generics [Uk] Limited | Crystalline forms of zofenopril calcium |
WO2010084515A2 (en) * | 2009-01-23 | 2010-07-29 | Glenmark Generics Limited | A process for the preparation of zofenopril and its pharmaceutically acceptable salts thereof |
SI23949A (sl) | 2011-12-19 | 2013-06-28 | Silverstone Pharma | Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji |
CN104138359B (zh) * | 2013-05-06 | 2016-03-02 | 扬子江药业集团上海海尼药业有限公司 | 佐芬普利钙片的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
US4316906A (en) | 1978-08-11 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of substituted prolines |
-
1998
- 1998-08-04 IT IT1998MI001833A patent/IT1301993B1/it active IP Right Grant
-
1999
- 1999-07-30 EA EA200100095A patent/EA003454B1/ru not_active IP Right Cessation
- 1999-07-30 BR BR9912842-0A patent/BR9912842A/pt not_active Application Discontinuation
- 1999-07-30 EE EEP200100065A patent/EE04798B1/xx unknown
- 1999-07-30 AT AT99939416T patent/ATE266635T1/de active
- 1999-07-30 PL PL99345814A patent/PL193828B1/pl unknown
- 1999-07-30 JP JP2000563619A patent/JP2002522417A/ja active Pending
- 1999-07-30 TR TR2001/00272T patent/TR200100272T2/xx unknown
- 1999-07-30 CA CA002339283A patent/CA2339283C/en not_active Expired - Lifetime
- 1999-07-30 IL IL14122299A patent/IL141222A0/xx not_active IP Right Cessation
- 1999-07-30 PT PT99939416T patent/PT1102745E/pt unknown
- 1999-07-30 SK SK163-2001A patent/SK285527B6/sk not_active IP Right Cessation
- 1999-07-30 WO PCT/EP1999/005461 patent/WO2000007984A1/en active IP Right Grant
- 1999-07-30 US US09/762,054 patent/US6521760B1/en not_active Expired - Fee Related
- 1999-07-30 AU AU53722/99A patent/AU5372299A/en not_active Abandoned
- 1999-07-30 UA UA2001010590A patent/UA65628C2/uk unknown
- 1999-07-30 CZ CZ20010408A patent/CZ301908B6/cs not_active IP Right Cessation
- 1999-07-30 HU HU0103826A patent/HU227557B1/hu unknown
- 1999-07-30 ES ES99939416T patent/ES2221417T3/es not_active Expired - Lifetime
- 1999-07-30 RS YUP-75/01A patent/RS49768B/sr unknown
- 1999-07-30 CN CNB998105171A patent/CN1146538C/zh not_active Expired - Lifetime
- 1999-07-30 SI SI9930575T patent/SI1102745T1/xx unknown
- 1999-07-30 DK DK99939416T patent/DK1102745T3/da active
- 1999-07-30 DE DE69917282T patent/DE69917282T2/de not_active Expired - Lifetime
- 1999-07-30 EP EP99939416A patent/EP1102745B1/de not_active Expired - Lifetime
- 1999-07-30 KR KR1020017001379A patent/KR100593428B1/ko not_active IP Right Cessation
-
2001
- 2001-01-24 BG BG105176A patent/BG65022B1/bg unknown
- 2001-02-01 HR HR20010083A patent/HRP20010083B1/xx not_active IP Right Cessation
- 2001-02-01 ZA ZA200100907A patent/ZA200100907B/en unknown
- 2001-02-01 CU CU20010032A patent/CU23171A3/es unknown
- 2001-02-01 NO NO20010552A patent/NO319773B1/no not_active IP Right Cessation
-
2002
- 2002-02-21 HK HK02101248.6A patent/HK1039616B/zh not_active IP Right Cessation
- 2002-05-28 US US10/155,129 patent/US6515012B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE366725T1 (de) | Verfahren zur herstellung von gereinigten 1,3- substituierten imidazoliumsalzen | |
ATE354541T1 (de) | Verfahren zur gewinnung von natriumarmem salz aus bitterwässern | |
DE69917282D1 (de) | Verfahren zur herstellung von zofenopril-calciumsalz | |
DE59904258D1 (de) | Verfahren zur Herstellung von Salzen von Ascorbyl-2-phosphorsäureestern | |
CA2425615A1 (en) | Process for the purification of gabapentin using a strong cation exchange resin | |
DE69905381T2 (de) | Umweltschonendes verfahren zur herstellung von natriumchloridkristallen | |
JPH10237030A (ja) | 分岐鎖アミノ酸の精製法 | |
EA200501734A1 (ru) | Способ получения (4-гидрокси-6-оксотетрагидропиран-2-ил)ацетонитрила и его производных | |
ATE302749T1 (de) | Verfahren zur herstellung von 5-aminosalicylsäure | |
DE69712328D1 (de) | Verfahren zur produktion von glutaminsäure | |
ATE233255T1 (de) | Verfahren zur herstellung von substituierten 2- benzo(b)thiophenekarbonsäuren und deren salzen | |
DE50109873D1 (de) | Verfahren zur herstellung von 1-methyl-3-nitroguanidin | |
WO2004087939A8 (en) | A process for the preparation of fludarabine phosphate from 2-fluoroadenine and fludarabine phosphate salts with amines or ammonia | |
ATE417117T1 (de) | Verfahren zur herstellung von 2-keto-l-gulonsäure | |
ATE233728T1 (de) | Verfahren zur reinigung von kreatin | |
DE69902674D1 (de) | Verfahren zur herstellung von alkalimetall- oder alkalimetall-erdalkalimetallformiaten | |
KR960004365A (ko) | 5'-리보뉴클레오티드칼슘의 제조방법 | |
DE50001638D1 (de) | Verfahren zur herstellung von 4,6-dichlorpyrimidin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |