CN1316992A - 佐芬普利钙盐的制备方法 - Google Patents
佐芬普利钙盐的制备方法 Download PDFInfo
- Publication number
- CN1316992A CN1316992A CN99810517A CN99810517A CN1316992A CN 1316992 A CN1316992 A CN 1316992A CN 99810517 A CN99810517 A CN 99810517A CN 99810517 A CN99810517 A CN 99810517A CN 1316992 A CN1316992 A CN 1316992A
- Authority
- CN
- China
- Prior art keywords
- zofenopril
- polymorphic form
- polymorph
- calcium
- zofenopril calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (15)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI001833A IT1301993B1 (it) | 1998-08-04 | 1998-08-04 | Processo per la preparazione di zofenopril sale di calcio. |
ITMI98A001833 | 1998-08-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1316992A true CN1316992A (zh) | 2001-10-10 |
CN1146538C CN1146538C (zh) | 2004-04-21 |
Family
ID=11380611
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB998105171A Expired - Lifetime CN1146538C (zh) | 1998-08-04 | 1999-07-30 | 佐芬普利钙盐的制备方法 |
Country Status (32)
Country | Link |
---|---|
US (2) | US6521760B1 (zh) |
EP (1) | EP1102745B1 (zh) |
JP (1) | JP2002522417A (zh) |
KR (1) | KR100593428B1 (zh) |
CN (1) | CN1146538C (zh) |
AT (1) | ATE266635T1 (zh) |
AU (1) | AU5372299A (zh) |
BG (1) | BG65022B1 (zh) |
BR (1) | BR9912842A (zh) |
CA (1) | CA2339283C (zh) |
CU (1) | CU23171A3 (zh) |
CZ (1) | CZ301908B6 (zh) |
DE (1) | DE69917282T2 (zh) |
DK (1) | DK1102745T3 (zh) |
EA (1) | EA003454B1 (zh) |
EE (1) | EE04798B1 (zh) |
ES (1) | ES2221417T3 (zh) |
HK (1) | HK1039616B (zh) |
HR (1) | HRP20010083B1 (zh) |
HU (1) | HU227557B1 (zh) |
IL (1) | IL141222A0 (zh) |
IT (1) | IT1301993B1 (zh) |
NO (1) | NO319773B1 (zh) |
PL (1) | PL193828B1 (zh) |
PT (1) | PT1102745E (zh) |
RS (1) | RS49768B (zh) |
SI (1) | SI1102745T1 (zh) |
SK (1) | SK285527B6 (zh) |
TR (1) | TR200100272T2 (zh) |
UA (1) | UA65628C2 (zh) |
WO (1) | WO2000007984A1 (zh) |
ZA (1) | ZA200100907B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101815702B (zh) * | 2007-08-10 | 2012-10-24 | 基因里克斯(英国)有限公司 | 新晶型 |
CN101981004B (zh) * | 2008-02-27 | 2014-09-17 | 基因里克斯(英国)有限公司 | 晶体形式 |
CN104138359A (zh) * | 2013-05-06 | 2014-11-12 | 扬子江药业集团上海海尼药业有限公司 | 佐芬普利钙片的制备方法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2560502T3 (es) | 2005-07-01 | 2016-02-19 | Generics [Uk] Limited | Zofenopril calcio en forma de polimorfo C |
EA012845B1 (ru) * | 2005-12-09 | 2009-12-30 | Менарини Интернэшнл Оперейшнс Люксембург С. А. | Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии |
DK2041083T3 (en) * | 2006-05-26 | 2015-01-26 | Generics Uk Ltd | Methods for the preparation of zofenopril calcium |
US8853421B2 (en) | 2008-02-27 | 2014-10-07 | Generics [Uk] Limited | Crystalline forms of zofenopril calcium |
EP2389360A4 (en) * | 2009-01-23 | 2013-01-16 | Glenmark Generics Ltd | METHOD FOR PRODUCING ZOFENOPRIL AND PHARMACEUTICAL ACCEPTIC SALTS THEREFOR |
SI23949A (sl) | 2011-12-19 | 2013-06-28 | Silverstone Pharma | Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
US4316906A (en) | 1978-08-11 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of substituted prolines |
-
1998
- 1998-08-04 IT IT1998MI001833A patent/IT1301993B1/it active IP Right Grant
-
1999
- 1999-07-30 CZ CZ20010408A patent/CZ301908B6/cs not_active IP Right Cessation
- 1999-07-30 RS YUP-75/01A patent/RS49768B/sr unknown
- 1999-07-30 EA EA200100095A patent/EA003454B1/ru not_active IP Right Cessation
- 1999-07-30 US US09/762,054 patent/US6521760B1/en not_active Expired - Fee Related
- 1999-07-30 SK SK163-2001A patent/SK285527B6/sk not_active IP Right Cessation
- 1999-07-30 HU HU0103826A patent/HU227557B1/hu unknown
- 1999-07-30 CN CNB998105171A patent/CN1146538C/zh not_active Expired - Lifetime
- 1999-07-30 BR BR9912842-0A patent/BR9912842A/pt not_active Application Discontinuation
- 1999-07-30 AU AU53722/99A patent/AU5372299A/en not_active Abandoned
- 1999-07-30 UA UA2001010590A patent/UA65628C2/uk unknown
- 1999-07-30 EP EP99939416A patent/EP1102745B1/en not_active Expired - Lifetime
- 1999-07-30 PT PT99939416T patent/PT1102745E/pt unknown
- 1999-07-30 ES ES99939416T patent/ES2221417T3/es not_active Expired - Lifetime
- 1999-07-30 KR KR1020017001379A patent/KR100593428B1/ko not_active IP Right Cessation
- 1999-07-30 WO PCT/EP1999/005461 patent/WO2000007984A1/en active IP Right Grant
- 1999-07-30 AT AT99939416T patent/ATE266635T1/de active
- 1999-07-30 EE EEP200100065A patent/EE04798B1/xx unknown
- 1999-07-30 CA CA002339283A patent/CA2339283C/en not_active Expired - Lifetime
- 1999-07-30 PL PL99345814A patent/PL193828B1/pl unknown
- 1999-07-30 SI SI9930575T patent/SI1102745T1/xx unknown
- 1999-07-30 TR TR2001/00272T patent/TR200100272T2/xx unknown
- 1999-07-30 DK DK99939416T patent/DK1102745T3/da active
- 1999-07-30 IL IL14122299A patent/IL141222A0/xx not_active IP Right Cessation
- 1999-07-30 JP JP2000563619A patent/JP2002522417A/ja active Pending
- 1999-07-30 DE DE69917282T patent/DE69917282T2/de not_active Expired - Lifetime
-
2001
- 2001-01-24 BG BG105176A patent/BG65022B1/bg unknown
- 2001-02-01 HR HR20010083A patent/HRP20010083B1/xx not_active IP Right Cessation
- 2001-02-01 CU CU20010032A patent/CU23171A3/es unknown
- 2001-02-01 NO NO20010552A patent/NO319773B1/no not_active IP Right Cessation
- 2001-02-01 ZA ZA200100907A patent/ZA200100907B/en unknown
-
2002
- 2002-02-21 HK HK02101248.6A patent/HK1039616B/zh not_active IP Right Cessation
- 2002-05-28 US US10/155,129 patent/US6515012B2/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101815702B (zh) * | 2007-08-10 | 2012-10-24 | 基因里克斯(英国)有限公司 | 新晶型 |
CN101981004B (zh) * | 2008-02-27 | 2014-09-17 | 基因里克斯(英国)有限公司 | 晶体形式 |
CN104138359A (zh) * | 2013-05-06 | 2014-11-12 | 扬子江药业集团上海海尼药业有限公司 | 佐芬普利钙片的制备方法 |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20200277266A1 (en) | Solid state forms of trisodium valsartan: sacubitril | |
US5843923A (en) | Glucosamine sulfate potassium chloride and process of preparation thereof | |
CN1146538C (zh) | 佐芬普利钙盐的制备方法 | |
NZ209962A (en) | Stable, crystalline form of prazosin hydrochloride | |
CN101981004B (zh) | 晶体形式 | |
KR20170060035A (ko) | 나트륨 글루코스 공동운반체 2 억제제의 l- 프롤린 화합물, 및 l- 프롤린 화합물의 모노하이드레이트 및 결정 | |
US6667420B2 (en) | Process for the preparation of sodium divalproate | |
JP4630549B2 (ja) | グルコサミン化合物の製造方法、及びその方法によって得られた化合物。 | |
MXPA01001253A (en) | A process for the preparation of zofenopril calcium salt | |
US20050113309A1 (en) | Crystalline forms(2s)-n-5[amino(imino)methyl]-2-thienylmethyl-1-(2r)-2[(carboxymethyl) amino]-3,3-diphenylpropanoyl-2-pyrrolidinecarboxamide nh2o | |
US20120046335A1 (en) | Solid states of atorvastatin potassium | |
JPH0597852A (ja) | プリン化合物の精製方法 | |
US20050165242A1 (en) | Process for the preparation of amorphous atorvastatin calcium | |
HUT66141A (en) | Cephalosporin salts and process for producing them | |
EP2794560A1 (en) | New crystal salts of zofenopril, process for obtaining them and their use in therapy |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: LUXEMBURG MEINALINI INTERNATIONAL OPERATION CO., Free format text: FORMER OWNER: MENARINI RICERCHE S.P.A. Effective date: 20040611 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20040611 Address after: Luxemburg Luxemburg Patentee after: Luxembourg Menarini International Operation Co., Ltd. Address before: Italy Pomezia Patentee before: Menarini Ricerche S. P. A. |
|
CX01 | Expiry of patent term |
Granted publication date: 20040421 |
|
CX01 | Expiry of patent term |