HRP20010083B1 - A process for the preparation of zofenopril calcium salt - Google Patents
A process for the preparation of zofenopril calcium saltInfo
- Publication number
- HRP20010083B1 HRP20010083B1 HR20010083A HRP20010083A HRP20010083B1 HR P20010083 B1 HRP20010083 B1 HR P20010083B1 HR 20010083 A HR20010083 A HR 20010083A HR P20010083 A HRP20010083 A HR P20010083A HR P20010083 B1 HRP20010083 B1 HR P20010083B1
- Authority
- HR
- Croatia
- Prior art keywords
- zofenopril
- salt
- calcium salt
- preparation
- potassium salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI001833A IT1301993B1 (it) | 1998-08-04 | 1998-08-04 | Processo per la preparazione di zofenopril sale di calcio. |
| PCT/EP1999/005461 WO2000007984A1 (en) | 1998-08-04 | 1999-07-30 | A process for the preparation of zofenopril calcium salt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20010083A2 HRP20010083A2 (en) | 2002-02-28 |
| HRP20010083B1 true HRP20010083B1 (en) | 2005-02-28 |
Family
ID=11380611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20010083A HRP20010083B1 (en) | 1998-08-04 | 2001-02-01 | A process for the preparation of zofenopril calcium salt |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US6521760B1 (xx) |
| EP (1) | EP1102745B1 (xx) |
| JP (1) | JP2002522417A (xx) |
| KR (1) | KR100593428B1 (xx) |
| CN (1) | CN1146538C (xx) |
| AT (1) | ATE266635T1 (xx) |
| AU (1) | AU5372299A (xx) |
| BG (1) | BG65022B1 (xx) |
| BR (1) | BR9912842A (xx) |
| CA (1) | CA2339283C (xx) |
| CU (1) | CU23171A3 (xx) |
| CZ (1) | CZ301908B6 (xx) |
| DE (1) | DE69917282T2 (xx) |
| DK (1) | DK1102745T3 (xx) |
| EA (1) | EA003454B1 (xx) |
| EE (1) | EE04798B1 (xx) |
| ES (1) | ES2221417T3 (xx) |
| HK (1) | HK1039616B (xx) |
| HR (1) | HRP20010083B1 (xx) |
| HU (1) | HU227557B1 (xx) |
| IL (1) | IL141222A0 (xx) |
| IT (1) | IT1301993B1 (xx) |
| NO (1) | NO319773B1 (xx) |
| PL (1) | PL193828B1 (xx) |
| PT (1) | PT1102745E (xx) |
| RS (1) | RS49768B (xx) |
| SI (1) | SI1102745T1 (xx) |
| SK (1) | SK285527B6 (xx) |
| TR (1) | TR200100272T2 (xx) |
| UA (1) | UA65628C2 (xx) |
| WO (1) | WO2000007984A1 (xx) |
| ZA (1) | ZA200100907B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2560502T3 (es) * | 2005-07-01 | 2016-02-19 | Generics [Uk] Limited | Zofenopril calcio en forma de polimorfo C |
| EA012845B1 (ru) * | 2005-12-09 | 2009-12-30 | Менарини Интернэшнл Оперейшнс Люксембург С. А. | Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии |
| SI2041083T1 (sl) * | 2006-05-26 | 2015-02-27 | Generics (Uk) Limited | Metode za pripravo zofenopril kalcija |
| GB0715626D0 (en) * | 2007-08-10 | 2007-09-19 | Generics Uk Ltd | Crystalline form of zofenopril calcium |
| AU2009219892B2 (en) * | 2008-02-27 | 2014-08-07 | Generics [Uk] Limited | Novel crystalline forms |
| US8853421B2 (en) | 2008-02-27 | 2014-10-07 | Generics [Uk] Limited | Crystalline forms of zofenopril calcium |
| EP2389360A4 (en) * | 2009-01-23 | 2013-01-16 | Glenmark Generics Ltd | METHOD FOR PRODUCING ZOFENOPRIL AND PHARMACEUTICAL ACCEPTIC SALTS THEREFOR |
| SI23949A (sl) | 2011-12-19 | 2013-06-28 | Silverstone Pharma | Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji |
| CN104138359B (zh) * | 2013-05-06 | 2016-03-02 | 扬子江药业集团上海海尼药业有限公司 | 佐芬普利钙片的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
| US4316906A (en) * | 1978-08-11 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of substituted prolines |
-
1998
- 1998-08-04 IT IT1998MI001833A patent/IT1301993B1/it active IP Right Grant
-
1999
- 1999-07-30 KR KR1020017001379A patent/KR100593428B1/ko not_active IP Right Cessation
- 1999-07-30 RS YUP-75/01A patent/RS49768B/sr unknown
- 1999-07-30 ES ES99939416T patent/ES2221417T3/es not_active Expired - Lifetime
- 1999-07-30 AU AU53722/99A patent/AU5372299A/en not_active Abandoned
- 1999-07-30 SK SK163-2001A patent/SK285527B6/sk not_active IP Right Cessation
- 1999-07-30 PT PT99939416T patent/PT1102745E/pt unknown
- 1999-07-30 IL IL14122299A patent/IL141222A0/xx not_active IP Right Cessation
- 1999-07-30 EA EA200100095A patent/EA003454B1/ru not_active IP Right Cessation
- 1999-07-30 JP JP2000563619A patent/JP2002522417A/ja active Pending
- 1999-07-30 EP EP99939416A patent/EP1102745B1/en not_active Expired - Lifetime
- 1999-07-30 UA UA2001010590A patent/UA65628C2/uk unknown
- 1999-07-30 US US09/762,054 patent/US6521760B1/en not_active Expired - Fee Related
- 1999-07-30 BR BR9912842-0A patent/BR9912842A/pt not_active Application Discontinuation
- 1999-07-30 CN CNB998105171A patent/CN1146538C/zh not_active Expired - Lifetime
- 1999-07-30 WO PCT/EP1999/005461 patent/WO2000007984A1/en active IP Right Grant
- 1999-07-30 CZ CZ20010408A patent/CZ301908B6/cs not_active IP Right Cessation
- 1999-07-30 PL PL99345814A patent/PL193828B1/pl unknown
- 1999-07-30 EE EEP200100065A patent/EE04798B1/xx unknown
- 1999-07-30 AT AT99939416T patent/ATE266635T1/de active
- 1999-07-30 DK DK99939416T patent/DK1102745T3/da active
- 1999-07-30 CA CA002339283A patent/CA2339283C/en not_active Expired - Lifetime
- 1999-07-30 SI SI9930575T patent/SI1102745T1/xx unknown
- 1999-07-30 HU HU0103826A patent/HU227557B1/hu unknown
- 1999-07-30 TR TR2001/00272T patent/TR200100272T2/xx unknown
- 1999-07-30 DE DE69917282T patent/DE69917282T2/de not_active Expired - Lifetime
-
2001
- 2001-01-24 BG BG105176A patent/BG65022B1/bg unknown
- 2001-02-01 ZA ZA200100907A patent/ZA200100907B/en unknown
- 2001-02-01 CU CU20010032A patent/CU23171A3/es unknown
- 2001-02-01 NO NO20010552A patent/NO319773B1/no not_active IP Right Cessation
- 2001-02-01 HR HR20010083A patent/HRP20010083B1/xx not_active IP Right Cessation
-
2002
- 2002-02-21 HK HK02101248.6A patent/HK1039616B/zh not_active IP Right Cessation
- 2002-05-28 US US10/155,129 patent/US6515012B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| PPPP | Transfer of rights |
Owner name: MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A., |
|
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20180627 Year of fee payment: 20 |
|
| PB20 | Patent expired after termination of 20 years |
Effective date: 20190730 |