EE03774B1 - 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks - Google Patents

5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Info

Publication number
EE03774B1
EE03774B1 EE9800065A EE9800065A EE03774B1 EE 03774 B1 EE03774 B1 EE 03774B1 EE 9800065 A EE9800065 A EE 9800065A EE 9800065 A EE9800065 A EE 9800065A EE 03774 B1 EE03774 B1 EE 03774B1
Authority
EE
Estonia
Prior art keywords
preparation
methylerythronolide
desosaminyl
derivatives
bioactive products
Prior art date
Application number
EE9800065A
Other languages
English (en)
Estonian (et)
Other versions
EE9800065A (et
Inventor
Bonnet Alain
Delthil Michel
Mazurie Alain
Original Assignee
Hoechst Marion Roussel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9482423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03774(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel
Publication of EE9800065A publication Critical patent/EE9800065A/xx
Publication of EE03774B1 publication Critical patent/EE03774B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EE9800065A 1995-09-11 1996-09-10 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks EE03774B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9510601A FR2738571B1 (fr) 1995-09-11 1995-09-11 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001384 WO1997010251A1 (fr) 1995-09-11 1996-09-10 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number Publication Date
EE9800065A EE9800065A (et) 1998-08-17
EE03774B1 true EE03774B1 (et) 2002-06-17

Family

ID=9482423

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800065A EE03774B1 (et) 1995-09-11 1996-09-10 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Country Status (34)

Country Link
US (1) US5969161A (cs)
EP (1) EP0854880B1 (cs)
JP (1) JP4332218B2 (cs)
KR (1) KR100457755B1 (cs)
CN (2) CN1070498C (cs)
AP (1) AP887A (cs)
AR (1) AR004195A1 (cs)
AT (1) ATE266035T1 (cs)
AU (1) AU708811B2 (cs)
BG (1) BG63822B1 (cs)
BR (1) BR9610503A (cs)
CA (1) CA2228670C (cs)
CZ (3) CZ294866B6 (cs)
DE (1) DE69632405T2 (cs)
DK (1) DK0854880T3 (cs)
EA (1) EA000575B1 (cs)
EE (1) EE03774B1 (cs)
ES (1) ES2219698T3 (cs)
FR (1) FR2738571B1 (cs)
GE (1) GEP20022838B (cs)
HK (1) HK1041489B (cs)
HU (1) HU227565B1 (cs)
IL (1) IL123550A (cs)
MX (1) MX9801859A (cs)
NO (2) NO312678B1 (cs)
PL (1) PL183652B1 (cs)
PT (1) PT854880E (cs)
RO (1) RO120137B1 (cs)
SI (1) SI0854880T1 (cs)
SK (3) SK285853B6 (cs)
TR (1) TR199800438T1 (cs)
UA (1) UA53628C2 (cs)
WO (1) WO1997010251A1 (cs)
ZA (1) ZA966837B (cs)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
RU2192427C2 (ru) * 1996-09-04 2002-11-10 Абботт Лаборэтриз Производные эритромицина, обладающие антибактериальной активностью, способ их получения (варианты), фармацевтическая композиция и способ регулирования бактериальной инфекции у млекопитающего
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6420535B1 (en) 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
AU2003219770B2 (en) * 2002-02-15 2008-10-09 Merckle Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
JP2005536465A (ja) * 2002-05-13 2005-12-02 エナンタ ファーマシューティカルズ インコーポレイテッド ６，１１二環式エリスロマイシン誘導体
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US6753318B1 (en) * 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7064110B2 (en) * 2002-05-13 2006-06-20 Enanta Pharmaceuticals, Inc. 6-11 bicycle ketolide derivatives
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
WO2005070918A1 (en) * 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US7135573B2 (en) * 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
WO2005030227A1 (en) * 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
US7414030B2 (en) 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
JP2008522978A (ja) 2004-12-07 2008-07-03 エナンタ ファーマシューティカルズ インコーポレイテッド ３，６−ビシクロライド
US7229972B2 (en) 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
US7291602B2 (en) 2004-12-13 2007-11-06 Enanta Pharmaceuticals, Inc. 11,12-lactone bicyclolides
WO2006065743A2 (en) 2004-12-13 2006-06-22 Enanta Pharmaceuticals, Inc. Tetracylic bicyclolides
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
CN101228171A (zh) * 2005-07-26 2008-07-23 默克勒有限公司 作为5-脂氧化酶和环加氧酶抑制剂的吡咯里嗪和中氮茚化合物的大环内酯偶联物
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
CN104004039A (zh) * 2007-09-17 2014-08-27 英安塔制药有限公司 6,11-桥联的联芳大环内酯类
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
CN103232501A (zh) * 2013-04-11 2013-08-07 宜昌东阳光药业股份有限公司 阿奇霉素或阿奇霉素的中间体脱去克拉定糖化合物的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives

Also Published As

Publication number Publication date
RO120137B1 (ro) 2005-09-30
EP0854880B1 (fr) 2004-05-06
ATE266035T1 (de) 2004-05-15
US5969161A (en) 1999-10-19
JP4332218B2 (ja) 2009-09-16
ZA966837B (en) 1997-08-13
EA000575B1 (ru) 1999-12-29
HU227565B1 (en) 2011-08-29
BR9610503A (pt) 1999-07-06
CN1201462A (zh) 1998-12-09
SK285995B6 (sk) 2008-01-07
IL123550A (en) 2002-09-12
AU708811B2 (en) 1999-08-12
DE69632405D1 (de) 2004-06-09
NO20021111D0 (no) 2002-03-06
PL326274A1 (en) 1998-08-31
BG63822B1 (bg) 2003-02-28
EP0854880A1 (fr) 1998-07-29
CZ294866B6 (cs) 2005-04-13
NO312678B1 (no) 2002-06-17
BG102312A (en) 1998-09-30
SK285853B6 (sk) 2007-09-06
AP887A (en) 2000-11-10
CZ71798A3 (cs) 1998-07-15
SK283690B6 (sk) 2003-12-02
IL123550A0 (en) 1998-10-30
ES2219698T3 (es) 2004-12-01
HK1016187A1 (en) 1999-10-29
DK0854880T3 (da) 2004-08-16
HK1041489B (zh) 2006-09-08
KR100457755B1 (ko) 2005-02-28
NO981053D0 (no) 1998-03-10
NO981053L (no) 1998-03-10
PL183652B1 (pl) 2002-06-28
NO315048B1 (no) 2003-06-30
UA53628C2 (uk) 2003-02-17
HUP9802930A1 (hu) 1999-04-28
PT854880E (pt) 2004-09-30
CN1237069C (zh) 2006-01-18
CZ294865B6 (cs) 2005-04-13
SI0854880T1 (en) 2004-12-31
AR004195A1 (es) 1998-11-04
JPH11512416A (ja) 1999-10-26
AU6991096A (en) 1997-04-01
CZ289945B6 (cs) 2002-04-17
CN1070498C (zh) 2001-09-05
SK29498A3 (en) 1998-12-02
WO1997010251A1 (fr) 1997-03-20
FR2738571B1 (fr) 1997-10-17
EA199800288A1 (ru) 1998-08-27
GEP20022838B (en) 2002-11-25
HUP9802930A3 (en) 1999-12-28
CA2228670A1 (fr) 1997-03-20
NO20021111L (no) 1998-03-10
KR19990044543A (ko) 1999-06-25
CN1319602A (zh) 2001-10-31
TR199800438T1 (xx) 1998-05-21
AP9801210A0 (en) 1998-03-31
CA2228670C (fr) 2005-04-12
HK1041489A1 (en) 2002-07-12
MX9801859A (es) 1998-11-30
DE69632405T2 (de) 2005-05-19
FR2738571A1 (fr) 1997-03-14
EE9800065A (et) 1998-08-17

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